3FDK
| Crystal structure of hydrolase DR0930 with promiscuous catalytic activity | 分子名称: | HYDROLASE DR0930, ZINC ION | 著者 | Fedorov, A.A, Fedorov, L.V, Xiang, D.F, Raushel, F.M, Almo, S.C. | 登録日 | 2008-11-25 | 公開日 | 2009-06-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily. Biochemistry, 48, 2009
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2WTF
| DNA polymerase eta in complex with the cis-diammineplatinum (II) 1,3- GTG intrastrand cross-link | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*TP*GP*GP*TP*GP*AP*GP*CP)-3', 5'-D(*TP*CP*TP*TP*CP*TP*GP*TP*GP*CP *TP*CP*AP*CP*CP*AP*CP)-3', ... | 著者 | Reissner, T, Schneider, S, Ziv, O, Schorr, S, Livneh, Z, Carell, T. | 登録日 | 2009-09-16 | 公開日 | 2010-03-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of a Cisplatin-(1,3-Gtg) Cross-Link within DNA Polymerase Eta. Angew.Chem.Int.Ed.Engl., 49, 2010
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4H2H
| Crystal structure of an enolase (mandalate racemase subgroup, target EFI-502101) from Pelagibaca bermudensis htcc2601, with bound mg and l-4-hydroxyproline betaine (betonicine) | 分子名称: | (2S,4R)-4-hydroxy-1,1-dimethylpyrrolidinium-2-carboxylate, (4S)-2-METHYL-2,4-PENTANEDIOL, IODIDE ION, ... | 著者 | Vetting, M.W, Morisco, L.L, Wasserman, S.R, Sojitra, S, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-09-12 | 公開日 | 2012-10-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of new enzymes and metabolic pathways by using structure and genome context. Nature, 502, 2013
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4YXO
| Human Carbonic Anhydrase II complexed with an inhibitor with a benzenesulfonamide group (3). | 分子名称: | 4-ethylbenzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... | 著者 | Rechlin, C, Heine, A, Klebe, G. | 登録日 | 2015-03-23 | 公開日 | 2016-02-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | Kinetic and Structural Insights into the Mechanism of Binding of Sulfonamides to Human Carbonic Anhydrase by Computational and Experimental Studies. J.Med.Chem., 59, 2016
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2CKJ
| Human milk xanthine oxidoreductase | 分子名称: | ACETIC ACID, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Pearson, A.R, Godber, B.L.J, Eisenthal, R, Taylor, G.L, Harrison, R. | 登録日 | 2006-04-19 | 公開日 | 2007-05-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | 主引用文献 | Human Milk Xanthine Dehydrogenase is Incompletely Converted to the Oxidase Form in the Absence of Proteolysis. A Structural Explanation. To be Published
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2CX9
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3FH6
| Crystal structure of the resting state maltose transporter from E. coli | 分子名称: | Maltose transport system permease protein malF, Maltose transport system permease protein malG, Maltose/maltodextrin import ATP-binding protein malK | 著者 | Khare, D, Oldham, M.L, Orelle, C, Davidson, A.L, Chen, J. | 登録日 | 2008-12-08 | 公開日 | 2009-03-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | Alternating access in maltose transporter mediated by rigid-body rotations. Mol.Cell, 33, 2009
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3FID
| LpxR from Salmonella typhimurium | 分子名称: | GLYCEROL, PENTAETHYLENE GLYCOL MONODECYL ETHER, Putative outer membrane protein (LpxR), ... | 著者 | Rutten, L, Gros, P. | 登録日 | 2008-12-11 | 公開日 | 2009-02-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Active-site architecture and catalytic mechanism of the lipid A deacylase LpxR of Salmonella typhimurium Proc.Natl.Acad.Sci.USA, 106, 2009
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5B26
| Crystal structure of mouse SEL1L | 分子名称: | Protein sel-1 homolog 1 | 著者 | Jeong, H, Lee, C. | 登録日 | 2016-01-09 | 公開日 | 2016-04-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway Sci Rep, 6, 2016
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3FJJ
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4Z0I
| Crystal structure of a tetramer of GluA2 ligand binding domains bound with glutamate at 1.45 Angstrom resolution | 分子名称: | DI(HYDROXYETHYL)ETHER, GLUTAMIC ACID, Glutamate receptor 2,Glutamate receptor 2, ... | 著者 | Baranovic, J, Chebli, M, Salazar, H, Carbone, A.L, Ghisi, V, Faelber, K, Lau, A.Y, Daumke, O, Plested, A.J.R. | 登録日 | 2015-03-26 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal structure of the tetrameric wt GluA2 ligand-binding domain bound to glutamate at 1.45 Angstroms resolution To Be Published
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1KAT
| Solution Structure of a Phage-Derived Peptide Antagonist in Complex with Vascular Endothelial Growth Factor | 分子名称: | Phage-Derived Peptide Antagonist, Vascular Endothelial Growth Factor | 著者 | Pan, B, Li, B, Russell, S.J, Tom, J.Y.K, Cochran, A.G, Fairbrother, W.J. | 登録日 | 2001-11-02 | 公開日 | 2002-11-02 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of a Phage-derived Peptide Antagonist in Complex with Vascular Endothelial Growth Factor J.Mol.Biol., 316, 2002
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4Z14
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2X4R
| Crystal structure of MHC CLass I HLA-A2.1 bound to Cytomegalovirus (CMV) pp65 epitope | 分子名称: | 65 KDA PHOSPHOPROTEIN, BETA-2-MICROGLOBULIN, GLYCEROL, ... | 著者 | Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M. | 登録日 | 2010-02-02 | 公開日 | 2010-03-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals. J.Am.Chem.Soc., 131, 2009
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4H1Y
| Human ecto-5'-nucleotidase (CD73): crystal form II (open) in complex with PSB11552 | 分子名称: | 2,2'-[(2-{[2-({[(2S,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]carbonyl}amino)ethyl]amino}-2-oxoethyl)imino]diacetic acid (non-preferred name), 5'-nucleotidase, CALCIUM ION, ... | 著者 | Pippel, J, Zebisch, M, Knapp, K, Straeter, N. | 登録日 | 2012-09-11 | 公開日 | 2012-11-28 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Crystal Structure of the Human Ecto-5'-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling. Structure, 20, 2012
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5B3D
| Structure of a flagellar type III secretion chaperone, FlgN | 分子名称: | Flagella synthesis protein FlgN | 著者 | Nakanishi, Y, Kinoshita, M, Namba, K, Minamino, T, Imada, K. | 登録日 | 2016-02-15 | 公開日 | 2016-06-01 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Rearrangements of alpha-helical structures of FlgN chaperone control the binding affinity for its cognate substrates during flagellar type III export Mol.Microbiol., 101, 2016
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2D00
| Subunit F of V-type ATPase/synthase | 分子名称: | CALCIUM ION, V-type ATP synthase subunit F | 著者 | Makyio, H, Iino, R, Ikeda, C, Imamura, H, Tamakoshi, M, Iwata, M, Stock, D, Bernal, R.A, Carpenter, E.P, Yoshida, M, Yokoyama, K, Iwata, S. | 登録日 | 2005-07-21 | 公開日 | 2005-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of a central stalk subunit F of prokaryotic V-type ATPase/synthase from Thermus thermophilus Embo J., 24, 2005
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5B4N
| Structure analysis of function associated loop mutant of substrate recognition domain of Fbs1 ubiquitin ligase | 分子名称: | F-box only protein 2 | 著者 | Nishio, K, Yoshida, Y, Tanaka, K, Mizushima, T. | 登録日 | 2016-04-06 | 公開日 | 2016-09-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural analysis of a function-associated loop mutant of the substrate-recognition domain of Fbs1 ubiquitin ligase Acta Crystallogr.,Sect.F, 72, 2016
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3FLP
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4ZM5
| Shigella flexneri lipopolysaccharide O-antigen chain-length regulator WzzBSF - A107P mutant | 分子名称: | CHLORIDE ION, Chain length determinant protein, MAGNESIUM ION | 著者 | Ericsson, D.J, Chang, C.-W, Lonhienne, T, Casey, L, Benning, F, Kobe, B, Tran, E.N.H, Morona, R. | 登録日 | 2015-05-02 | 公開日 | 2016-03-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Structural and Biochemical Analysis of a Single Amino-Acid Mutant of WzzBSF That Alters Lipopolysaccharide O-Antigen Chain Length in Shigella flexneri. Plos One, 10, 2015
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6BQD
| TAF1-BD2 bromodomain in complex with (E)-3-(6-(but-2-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,N-dimethylbenzamide | 分子名称: | 3-{6-[(2E)-but-2-en-1-yl]-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl}-N,N-dimethylbenzamide, Transcription initiation factor TFIID subunit 1 | 著者 | Murray, J.M, Tang, Y. | 登録日 | 2017-11-27 | 公開日 | 2019-02-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.136 Å) | 主引用文献 | Water molecules in protein-ligand interfaces. Evaluation of software tools and SAR comparison. J. Comput. Aided Mol. Des., 33, 2019
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6BSC
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5AP0
| Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. | 分子名称: | 1,2-ETHANEDIOL, 9-CYCLOPENTYL-2-[[2-METHOXY-4-[(1-METHYLPIPERIDIN-4-YL)OXY]-PHENYL]AMINO]-7-METHYL-7,9-DIHYDRO-8H-PURIN-8-ONE, DIMETHYL SULFOXIDE, ... | 著者 | Gurden, M.D, Westwood, I.M, Faisal, A, Naud, S, Cheung, K.J, McAndrew, C, Wood, A, Schmitt, J, Boxall, K, Mak, G, Workman, P, Burke, R, Hoelder, S, Blagg, J, van Montfort, R.L.M, Linardopoulos, S. | 登録日 | 2015-09-14 | 公開日 | 2015-09-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Naturally Occurring Mutations in the Mps1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. Cancer Res., 75, 2015
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4Z6E
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3FJG
| Crystal structure of 3PG bound PEB3 | 分子名称: | 3-PHOSPHOGLYCERIC ACID, Major antigenic peptide PEB3 | 著者 | Min, T, Matte, A, Cygler, M. | 登録日 | 2008-12-14 | 公開日 | 2009-03-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Specificity of Campylobacter jejuni adhesin PEB3 for phosphates and structural differences among its ligand complexes. Biochemistry, 48, 2009
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