PDB: 47902 件ウェブページステータス検索Chemie searchBIRD

---

1LRM	Crystal structure of binary complex of the catalytic domain of human phenylalanine hydroxylase with dihydrobiopterin (BH2) 分子名称: 7,8-DIHYDROBIOPTERIN, FE (III) ION, Phenylalanine-4-hydroxylase 著者 Andersen, O.A. 登録日 2002-05-15 公開日 2002-06-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献
5CB5	Structural Insights into the Mechanism of Escherichia coli Ymdb 分子名称: ACETATE ION, ADENOSINE-5-DIPHOSPHORIBOSE, O-acetyl-ADP-ribose deacetylase, ... 著者 Zhang, W, Wang, C, Song, Y, Shao, C, Zhang, X, Zang, J. 登録日 2015-06-30 公開日 2015-11-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural insights into the mechanism of Escherichia coli YmdB: A 2'-O-acetyl-ADP-ribose deacetylase J.Struct.Biol., 192, 2015
4YHW	Yeast Prp3 (296-469) in complex with fragment of U4/U6 di-snRNA 分子名称: U4 snRNA fragment, U4/U6 small nuclear ribonucleoprotein PRP3, U6 snRNA fragment 著者 Liu, S, Wahl, M.C. 登録日 2015-02-27 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing. Elife, 4, 2015
6XHG	Far-red absorbing dark state of JSC1_58120g3 with bound biliverdin IXa (BV) 分子名称: 1,2-ETHANEDIOL, 3-[2-[(~{Z})-[5-[(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-2-ylidene]methyl]-5-[(~{Z})-(3-ethyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, JSC1_58120g3 著者 Moreno, M.V, Rockwell, N.C, Fisher, A.J, Lagarias, J.C. 登録日 2020-06-18 公開日 2020-10-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A far-red cyanobacteriochrome lineage specific for verdins. Proc.Natl.Acad.Sci.USA, 117, 2020
5CCV	Crystal structure of full-length NS5 from dengue virus type 3 分子名称: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Klema, V.J, Choi, K.H. 登録日 2015-07-02 公開日 2016-02-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface. Plos Pathog., 12, 2016
4YJ4	Crystal structure of Bcl-xL in complex with the BIM BH3 domain containing Ile155-to-Arg and Glu158-to-phosphoserine mutations 分子名称: ACETATE ION, Bcl-2-like protein 1, BIM BH3 domain, ... 著者 Ku, B, Ha, N.-C, Oh, B.-H. 登録日 2015-03-03 公開日 2015-07-29 最終更新日 2017-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Conversion of cell-survival activity of Akt into apoptotic death of cancer cells by two mutations on the BIM BH3 domain. Cell Death Dis, 6, 2015
6XCB	Structure of the C. botulinum neurotoxin serotype A light chain protease in complex with covalent inhibitor 20 分子名称: Botulinum neurotoxin type A, N-hydroxy-6-sulfanylhexanamide, ZINC ION 著者 Tararina, M.A, Allen, K.N. 登録日 2020-06-08 公開日 2020-09-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A. J.Med.Chem., 63, 2020
6AUA	CRYSTAL STRUCTURE OF BRUTON'S TYROSINE KINASE IN COMPLEX WITH INHIBITOR CGI2625 分子名称: GLYCEROL, N-{3-[(2R)-6-{[3-amino-4-(morpholine-4-carbonyl)phenyl]amino}-5-oxo-2,5-dihydropyrazin-2-yl]-2-methylphenyl}-4-(piperidin-1-yl)benzamide, SULFATE ION, ... 著者 Davies, D.R, Staker, B.L. 登録日 2017-08-31 公開日 2018-09-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 To Be Determined TO BE PUBLISHED
1LDL	THREE-DIMENSIONAL STRUCTURE OF A CYSTEINE-RICH REPEAT FROM THE LOW-DENSITY LIPOPROTEIN RECEPTOR 分子名称: LOW-DENSITY LIPOPROTEIN RECEPTOR 著者 Daly, N.L, Scanlon, M.J, Kroon, P.A, Smith, R. 登録日 1995-03-20 公開日 1996-03-08 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor. Proc.Natl.Acad.Sci.USA, 92, 1995
6XCM	Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2020-06-08 公開日 2020-07-01 最終更新日 2020-09-02 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies. Cell, 182, 2020
4J7X	Crystal structure of human sepiapterin reductase in complex with sulfasalazine 分子名称: 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Groenlund Pedersen, M, Pojer, F, Johnsson, K. 登録日 2013-02-14 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of human sepiapterin reductase in complex with sulfasalazine To be Published
6AUP	Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox 分子名称: GLYCEROL, Potassium channel toxin gamma-KTx 2.2, SULFATE ION 著者 Gewe, M.M, Rupert, P, Strong, R.K. 登録日 2017-09-01 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25, 2018
2XDQ	Dark Operative Protochlorophyllide Oxidoreductase (ChlN-ChlB)2 Complex 分子名称: 1-METHYLGUANIDINE, IRON/SULFUR CLUSTER, LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B, ... 著者 Broecker, M.J, Schomburg, S, Heinz, D.W, Jahn, D, Schubert, W.-D, Moser, J. 登録日 2010-05-06 公開日 2010-06-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Nitrogenase-Like Dark Operative Protochlorophyllide Oxidoreductase Catalytic Complex (Chln/Chlb)2. J.Biol.Chem., 285, 2010
6AV0	Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5-(3-(methylamino)propyl)benzonitrile 分子名称: 3-[2-(6-amino-4-methylpyridin-2-yl)ethyl]-5-[3-(methylamino)propyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric oxide synthase, ... 著者 LI, H, Poulos, T.L. 登録日 2017-09-01 公開日 2018-07-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.996 Å) 主引用文献 Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker. J. Med. Chem., 60, 2017
6AUM	Crystal structure of human soluble epoxide hydrolase complexed with trans-4-[4-(3-trifluoromethoxyphenyl-l-ureido)-cyclohexyloxy]-benzoic acid. 分子名称: 4-{[trans-4-({[4-(trifluoromethoxy)phenyl]carbamoyl}amino)cyclohexyl]oxy}benzoic acid, Bifunctional epoxide hydrolase 2, CHLORIDE ION, ... 著者 Kodani, S.D, Bahkta, S, Hwang, S.H, Pakhomova, S, Newcomer, M.E, Morisseau, C, Hammock, B. 登録日 2017-09-01 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorg. Med. Chem. Lett., 28, 2018
1L6U	NMR STRUCTURE OF OXIDIZED ADRENODOXIN 分子名称: Adrenodoxin 1, FE2/S2 (INORGANIC) CLUSTER 著者 Beilke, D, Weiss, R, Lohr, F, Pristovsek, P, Hannemann, F, Bernhardt, R, Rueterjans, H. 登録日 2002-03-14 公開日 2002-06-26 最終更新日 2020-02-05 実験手法 SOLUTION NMR 主引用文献 A new electron transport mechanism in mitochondrial steroid hydroxylase systems based on structural changes upon the reduction of adrenodoxin. Biochemistry, 41, 2002
2E01	Crystal structure of H369A mutant of yeast bleomycin hydrolase 分子名称: Cysteine proteinase 1 著者 O'Farrell, P.A, Joshua-Tor, L. 登録日 2006-10-01 公開日 2007-08-14 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure Biochem.J., 401, 2007
6AV1	Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(Dimethylamino)propyl)-5-fluorophenethyl)-4-methylpyridin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-(2-{3-[3-(dimethylamino)propyl]-5-fluorophenyl}ethyl)-4-methylpyridin-2-amine, Nitric oxide synthase, ... 著者 Li, H, Poulos, T.L. 登録日 2017-09-01 公開日 2018-07-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker. J. Med. Chem., 60, 2017
5CJ0	Crystal Structure of Amino Acids 1631-1692 of MYH7 分子名称: Xrcc4-MYH7-(1631-1692) chimera protein 著者 Korkmaz, N.E, Taylor, K.C, Andreas, M.P, Ajay, G, Heinze, N.T, Cui, Q, Rayment, I. 登録日 2015-07-13 公開日 2015-12-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A composite approach towards a complete model of the myosin rod. Proteins, 84, 2016
3DP6	Crystal structure of the binding domain of the AMPA subunit GluR2 bound to glutamate 分子名称: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION 著者 Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E. 登録日 2008-07-07 公開日 2008-11-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure of the S1S2 glutamate binding domain of GLuR3. Proteins, 75, 2008
5CJY	Crystal structure of a B-form DNA duplex containing 5-hydroxylmethylcytidine 分子名称: DNA (5'-D(*CP*GP*(5HC)P*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION 著者 Sheng, J. 登録日 2015-07-15 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of a B-form DNA duplex containing 5-hydroxylmethylcytidine To Be Published
3DQB	Crystal structure of the active G-protein-coupled receptor opsin in complex with a C-terminal peptide derived from the Galpha subunit of transducin 分子名称: 11meric peptide form Guanine nucleotide-binding protein G(t) subunit alpha-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... 著者 Scheerer, P, Park, J.H, Hildebrand, P.W, Kim, Y.J, Krauss, N, Choe, H.-W, Hofmann, K.P, Ernst, O.P. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of opsin in its G-protein-interacting conformation Nature, 455, 2008
2XC3	X-ray structure of Mycobacterium tuberculosis cyp125 bound to the reverse type I inhibitor 分子名称: NALPHA-[(TRANS-4-METHYLCYCLOHEXYL)CARBONYL]-N-PYRIDIN-4-YL-D-TRYPTOPHANAMIDE, PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 125 著者 Ouellet, H, Kells, P.M, Ortiz de Montellano, P.R, Podust, L.M. 登録日 2010-04-16 公開日 2010-11-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Reverse Type I Inhibitor of Mycobacteriumtuberculosis Cyp125A1. Bioorg.Med.Chem.Lett., 21, 2011
5CGD	Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator 3-chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile - (HTL14242) 分子名称: 3-chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile, Metabotropic glutamate receptor 5,Endolysin,Metabotropic glutamate receptor 5, OLEIC ACID 著者 Christopher, J.A, Aves, S.J, Bennett, K.A, Dore, A.S, Errey, J.C, Jazayeri, A, Marshall, F.H, Okrasa, K, Serrano-Vega, M.J, Tehan, B.G, Wiggin, G.R, Congreve, M. 登録日 2015-07-09 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.603 Å) 主引用文献 Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile). J.Med.Chem., 58, 2015
6AXF	Structure of RasGRP2 in complex with Rap1B 分子名称: RAS guanyl-releasing protein 2, Ras-related protein Rap-1b 著者 Kondo, Y, Iwig, J.S, Kuriyan, J. 登録日 2017-09-06 公開日 2017-10-11 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1. Elife, 6, 2017

<1020102110221023102410251026102710281029103010311032103310341035>