PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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8T59	Crystal structure of Para.09 bound to TREM2 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Para.09 heavy chain, ... 著者 Wallweber, H, Hsu, P.L. 登録日 2023-06-12 公開日 2024-07-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining To Be Published
8TRV	Structure of the EphA2 LBDCRD bound to FabS1C_C1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Ephrin type-A receptor 2, ... 著者 Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. 登録日 2023-08-10 公開日 2024-07-17 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Synthetic Antibodies targeting EPHA2 Induce Diverse Signaling-Competent Clusters with Differential Activation To be Published
6DBZ	Crystal structure of Nudix 1 from Arabidopsis thaliana complexed with isopentenyl diphosphate 分子名称: ISOPENTYL PYROPHOSPHATE, MAGNESIUM ION, Nudix hydrolase 1 著者 Noel, J.P, Thomas, S.T, Dudareva, N, Henry, L.K. 登録日 2018-05-03 公開日 2018-09-19 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Contribution of isopentenyl phosphate to plant terpenoid metabolism. Nat Plants, 4, 2018
6DC1	Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-nitro-2-oxidanyl-benzenecarbonitrile, ... 著者 Jackson, C.J, Hong, N.-S, Carr, P.D. 登録日 2018-05-03 公開日 2018-08-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9, 2018
8TRR	T cell recognition of citrullinated vimentin peptide presented by HLA-DR4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Loh, T.J, Lim, J.J, Reid, H.H, Rossjohn, J. 登録日 2023-08-10 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4. Nat Commun, 15, 2024
5TG0	Crystal structure of the dimethylsulfoniopropionate (DMSP) lyase DddK complexed with iron and zinc 分子名称: FE (III) ION, ZINC ION, dimethylsulfoniopropionate lyase DddK 著者 Schnicker, N.J, Dey, M. 登録日 2016-09-27 公開日 2017-06-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Structural and Biochemical Insights into Dimethylsulfoniopropionate Cleavage by Cofactor-Bound DddK from the Prolific Marine Bacterium Pelagibacter. Biochemistry, 56, 2017
6DKE	The X-ray crystal structure of Streptococcus pneumoniae Fatty Acid Kinase (Fak) B1 protein loaded with palmitic acid (C16:0) to 1.76 Angstrom resolution 分子名称: Fatty Acid Kinase (Fak) B1 protein, PALMITIC ACID 著者 Cuypers, M.G, Subramanian, C, White, S.W, Rock, C.O. 登録日 2018-05-29 公開日 2019-05-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 The X-ray crystal structure of Streptococcus pneumoniae Fatty Acid Kinase (Fak) B1 protein loaded with palmitic acid (C16:0) to 1.76 Angstrom resolution To Be Published
8TTT	Structure of SNX27 FERM complexed with Fam21A repeat 15 (1124-1140) 分子名称: DI(HYDROXYETHYL)ETHER, Fam21A repeat 15 peptide, GLYCEROL, ... 著者 Guo, Q, Chen, K.-E, Collins, B.M. 登録日 2023-08-15 公開日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex. Proc.Natl.Acad.Sci.USA, 121, 2024
6IFF	Crystal structure of M1 zinc metallopeptidase E323A mutant from Deinococcus radiodurans 分子名称: SODIUM ION, TYROSINE, ZINC ION, ... 著者 Agrawal, R, Kumar, A, Kumar, A, Gaur, N.K, Makde, R.D. 登録日 2018-09-20 公開日 2019-09-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structural basis for the unusual substrate specificity of unique two-domain M1 metallopeptidase. Int.J.Biol.Macromol., 147, 2020
6DG5	Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... 著者 Jude, K.M, Silva, D.-A, Yu, S, Baker, D, Garcia, K.C. 登録日 2018-05-16 公開日 2019-01-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.516 Å) 主引用文献 De novo design of potent and selective mimics of IL-2 and IL-15. Nature, 565, 2019
5G01	An unusual natural product primary sulfonamide: synthesis, carbonic anhydrase inhibition and protein x-ray structure of Psammaplin C 分子名称: CARBONIC ANHYDRASE 2, PSAMMAPLIN C, SODIUM ION, ... 著者 Mujumdar, P, Supuran, C.T, Peat, T.S, Poulsen, S.A. 登録日 2016-03-16 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition and Protein X-Ray Structures of Psammaplin C. J.Med.Chem., 59, 2016
8TQF	Crystal structure of Soybean SHMT8 in complex with PLP-glycine and diglutamylated 5-formyltetrahydrofolate 分子名称: 1,2-ETHANEDIOL, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N-[4-({[(6R)-2-amino-5-formyl-4-hydroxy-5,6,7,8-tetrahydropteridin-6-yl]methyl}amino)benzoyl]-L-gamma-glutamyl-L-glutamic acid, ... 著者 Owuocha, L.F, Beamer, L.J. 登録日 2023-08-07 公開日 2024-08-21 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structural insights into high affinity binding of polyglutamylated tetrahydrofolate to soybean serine hydroxymethyltransferase To Be Published
5FNR	Structure of the Keap1 Kelch domain in complex with a small molecule inhibitor. 分子名称: (3S)-3-(4-chlorophenyl)-3-(1-methylbenzotriazol-5-yl)propanoic acid, KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 著者 Davies, T.G, Wixted, W.E, Coyle, J.E, Griffiths-Jones, C, Hearn, K, McMenamin, R, Norton, D, Rich, S.J, Richardson, C, Saxty, G, Willems, H.M.G, Woolford, A.J, Cottom, J.E, Kou, J, Yonchuk, J.G, Feldser, H.G, Sanchez, Y, Foley, J.P, Bolognese, B.J, Logan, G, Podolin, P.L, Yan, H, Callahan, J.F, Heightman, T.D, Kerns, J.K. 登録日 2015-11-16 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Mono-Acidic Inhibitors of the Kelch-Like Ech-Associated Protein 1 : Nuclear Factor Erythroid 2-Related Factor 2 (Keap1:Nrf2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. J.Med.Chem., 59, 2016
6KGL	LSD1-CoREST-S2101 N5 adduct model 分子名称: 3-[3,5-bis(fluoranyl)-2-phenylmethoxy-phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Niwa, H, Sato, S, Sengoku, S, Umehara, T, Yokoyama, S. 登録日 2019-07-12 公開日 2020-03-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Development and Structural Evaluation of N-Alkylated trans-2-Phenylcyclopropylamine-Based LSD1 Inhibitors. Chemmedchem, 15, 2020
5WZT	Crystal structure of human secreted phospholipase A2 group IIE with Compound 14 分子名称: 2-[1-[(3-bromophenyl)methyl]-2-methyl-3-oxamoyl-indol-4-yl]oxyethanoic acid, CALCIUM ION, DIMETHYL SULFOXIDE, ... 著者 Hou, S, Xu, J, Xu, T, Liu, J. 登録日 2017-01-18 公開日 2018-01-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE Sci Rep, 7, 2017
8TTV	Structure of SNX27 FERM complexed with Fam21A repeat 20 (1289-1302) 分子名称: DI(HYDROXYETHYL)ETHER, Fam21A repeat 20 peptide, Sorting nexin-27 著者 Guo, Q, Chen, K.-E, Collins, B.M. 登録日 2023-08-15 公開日 2024-08-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex. Proc.Natl.Acad.Sci.USA, 121, 2024
7LTD	X-ray radiation damage series on Proteinase K at 100K, crystal structure, dataset 1 分子名称: CALCIUM ION, NITRATE ION, Proteinase K 著者 Yabukarski, F, Doukov, T, Herschlag, D. 登録日 2021-02-19 公開日 2022-08-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (0.9 Å) 主引用文献 Evaluating the impact of X-ray damage on conformational heterogeneity in room-temperature (277 K) and cryo-cooled protein crystals. Acta Crystallogr D Struct Biol, 78, 2022
6JW9	Crystal structure of E-64 inhibited falcipain 2 from Plasmodium falciparum, strain 3D7 分子名称: Cysteine protease falcipain-2, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE 著者 Chakraborty, S, Alam, B, Biswas, S. 登録日 2019-04-18 公開日 2020-04-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 New insights of falcipain 2 structure from Plasmodium falciparum 3D7 strain. Biochem.Biophys.Res.Commun., 590, 2022
8TOZ	Class III PreQ1 riboswitch double mutant U8C/A85G 分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, Class-III preQ1 riboswitch 著者 Srivastava, Y, Jenkins, J.L, Wedekind, J.E. 登録日 2023-08-04 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 New insights into Class III PreQ1 metabolite binding To Be Published
5FTH	Crystal structure of the GluA2 K738M-T744K LBD in complex with glutamate (zinc form) 分子名称: GLUTAMATE RECEPTOR 2, GLUTAMIC ACID, ZINC ION 著者 Nayeem, N, Green, T. 登録日 2016-01-13 公開日 2016-02-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Distinct Structural Pathways Coordinate the Activation of Ampa Receptor-Auxiliary Subunit Complexes. Neuron, 89, 2016
6DOB	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 200 s at 21 C 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.343 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
7LTI	X-ray radiation damage series on Proteinase K at 100K, crystal structure, dataset 2 分子名称: CALCIUM ION, NITRATE ION, Proteinase K 著者 Yabukarski, F, Doukov, T, Herschlag, D. 登録日 2021-02-19 公開日 2022-08-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (0.91 Å) 主引用文献 Evaluating the impact of X-ray damage on conformational heterogeneity in room-temperature (277 K) and cryo-cooled protein crystals. Acta Crystallogr D Struct Biol, 78, 2022
7LTV	X-ray radiation damage series on Proteinase K at 100K, crystal structure, dataset 3 分子名称: CALCIUM ION, NITRATE ION, Proteinase K 著者 Yabukarski, F, Doukov, T, Herschlag, D. 登録日 2021-02-20 公開日 2022-08-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Evaluating the impact of X-ray damage on conformational heterogeneity in room-temperature (277 K) and cryo-cooled protein crystals. Acta Crystallogr D Struct Biol, 78, 2022
6DOL	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 25 mM K+ for 120 s at 21 C (dataset 2) 分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), 5'-R(P*CP*G)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.433 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
7LU0	X-ray radiation damage series on Proteinase K at 100K, crystal structure, dataset 4 分子名称: CALCIUM ION, NITRATE ION, Proteinase K 著者 Yabukarski, F, Doukov, T, Herschlag, D. 登録日 2021-02-20 公開日 2022-08-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.01 Å) 主引用文献 Evaluating the impact of X-ray damage on conformational heterogeneity in room-temperature (277 K) and cryo-cooled protein crystals. Acta Crystallogr D Struct Biol, 78, 2022

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