6H7O
 
 | | ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND WEAK PARTIAL AGONIST CYANOPINDOLOL AND NANOBODY Nb6B9 | | 分子名称: | 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, ... | | 著者 | Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G. | | 登録日 | 2018-07-31 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019
|
|
6CGP
 | | Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with MAIP-032 | | 分子名称: | 1,2-ETHANEDIOL, Hdac6 protein, N-hydroxy-4-[(2-propylimidazo[1,2-a]pyridin-3-yl)amino]benzamide, ... | | 著者 | Osko, J.D, Christianson, D.W. | | 登録日 | 2018-02-20 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Multicomponent Synthesis and Binding Mode of Imidazo[1,2- a]pyridine-Capped Selective HDAC6 Inhibitors.
Org. Lett., 20, 2018
|
|
7L4Z
 | | Structure of SARS-CoV-2 spike RBD in complex with cyclic peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-DTY-LYS-ALA-GLY-VAL-VAL-TYR-GLY-TYR-ASN-ALA-TRP-ILE-ARG-CYS-NH2, Spike protein S1 | | 著者 | Christie, M, Mackay, J.P, Passioura, T, Payne, R.J. | | 登録日 | 2020-12-21 | | 公開日 | 2021-06-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.96 Å) | | 主引用文献 | Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display.
Acs Cent.Sci., 7, 2021
|
|
6IVQ
 | | Crystal structure of a membrane protein S19A | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | | 著者 | Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. | | 登録日 | 2018-12-04 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
|
|
6RA9
 | | Novel structural features and post-translational modifications in eukaryotic elongation factor 1A2 from Oryctolagus cuniculus | | 分子名称: | Elongation factor 1-alpha 2, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Carriles, A.A, Hermoso, J, Gago, F. | | 登録日 | 2019-04-05 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Cues for Understanding eEF1A2 Moonlighting.
Chembiochem, 22, 2021
|
|
6IOV
 | | The ligand binding domain of Mlp37 with arginine | | 分子名称: | ARGININE, Methyl-accepting chemotaxis (MCP) signaling domain protein | | 著者 | Takahashi, Y, Sumita, K, Nishiyama, S, Kawagishi, I, Imada, K. | | 登録日 | 2018-10-31 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.351 Å) | | 主引用文献 | Structural basis of the binding affinity of chemoreceptors Mlp24p and Mlp37p for various amino acids.
Biochem.Biophys.Res.Commun., 523, 2020
|
|
6CEU
 | | MBD3 MBD in complex with methylated, non-palindromic CpG DNA: alternative interpretation of crystallographic data | | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*CP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*GP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 3, ... | | 著者 | Liu, K, Tempel, W, Wernimont, A.K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2018-02-12 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | | 主引用文献 | Structural analyses reveal that MBD3 is a methylated CG binder.
Febs J., 286, 2019
|
|
5WMX
 | | Structural Insights into Substrate and Inhibitor Binding Sites in Human Indoleamine 2,3-Dioxygenase 1 | | 分子名称: | 2-(1H-indol-3-yl)ethanol, CYANIDE ION, Indoleamine 2,3-dioxygenase 1, ... | | 著者 | Lewis-Ballester, A, Yeh, S.R, Pham, K.N, Batabyal, D, Karkashon, S, Bonanno, J.B, Poulos, T.M. | | 登録日 | 2017-07-31 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1.
Nat Commun, 8, 2017
|
|
6GYH
 | | Crystal structure of the light-driven proton pump Coccomyxa subellipsoidea Rhodopsin CsR | | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Family A G protein-coupled receptor-like protein, ... | | 著者 | Szczepek, M, Schmidt, A, Scheerer, P. | | 登録日 | 2018-06-29 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Design of a light-gated proton channel based on the crystal structure ofCoccomyxarhodopsin.
Sci.Signal., 12, 2019
|
|
6CH4
 | |
5WO3
 | | Chaperone Spy bound to Im7 (Im7 un-modeled) | | 分子名称: | CHLORIDE ION, IMIDAZOLE, Periplasmic chaperone Spy, ... | | 著者 | Horowitz, S, Koldewey, P, Martin, R, Bardwell, J.C.A. | | 登録日 | 2017-08-01 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Visualizing chaperone-assisted protein folding.
Nat. Struct. Mol. Biol., 23, 2016
|
|
7KIL
 | |
5HUD
 | | Non-covalent complex of and DAHP synthase and chorismate mutase from Corynebacterium glutamicum with bound transition state analog | | 分子名称: | 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, Chorismate mutase, ... | | 著者 | Burschowsky, D, Heim, J.B, Thorbjoernsrud, H.V, Krengel, U. | | 登録日 | 2016-01-27 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp.
Biochemistry, 57, 2018
|
|
6RC0
 | |
5WOP
 | | High Resolution Structure of Mutant CA09-PB2cap | | 分子名称: | GLYCEROL, Polymerase PB2 | | 著者 | Constantinides, A.E, Gumpper, R.H, Severin, C, Luo, M. | | 登録日 | 2017-08-02 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | High-resolution structure of the Influenza A virus PB2cap binding domain illuminates the changes induced by ligand binding.
Acta Crystallogr F Struct Biol Commun, 74, 2018
|
|
8T51
 | |
5HYM
 | | 3-Hydroxybenzoate 6-hydroxylase from Rhodococcus jostii in complex with phosphatidylinositol | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Phosphatidylinositol, ... | | 著者 | Orru, R, Montersino, S, Mattevi, A, van Berkel, W.J.H. | | 登録日 | 2016-02-01 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | 3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor.
Front Microbiol, 8, 2017
|
|
6RCL
 | | Crystal structure of REXO2-D199A-AA | | 分子名称: | MAGNESIUM ION, Oligoribonuclease, mitochondrial, ... | | 著者 | Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M. | | 登録日 | 2019-04-11 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.
Mol.Cell, 76, 2019
|
|
8C7U
 | |
6GZW
 | |
7KIH
 | |
8C7O
 | |
8TCS
 | | Structure of trehalose bound Alistipes sp. 3-Keto-beta-glucopyranoside-1,2-Lyase AL1 | | 分子名称: | ACETATE ION, COBALT (II) ION, Xylose isomerase-like TIM barrel domain-containing protein, ... | | 著者 | Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J. | | 登録日 | 2023-07-02 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
|
|
5WPJ
 | |
6IA7
 | | T. brucei IFT22 GTP-bound crystal structure | | 分子名称: | CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, Intraflagellar transport protein 22, ... | | 著者 | Wachter, S, Basquin, J, Lorentzen, E. | | 登録日 | 2018-11-26 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly.
Embo J., 38, 2019
|
|
