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1GN4
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H145E mutant of Mycobacterium tuberculosis iron-superoxide dismutase.
分子名称: MANGANESE (II) ION, SUPEROXIDE DISMUTASE
著者Bunting, K.A, Cooper, J.B, Badasso, M.O, Tickle, I.J, Newton, M, Wood, S.P, Zhang, Y, Young, D.B.
登録日2001-10-02
公開日2001-10-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Engineering a Change in the Metal-Ion Specificity of the Iron-Depedent Superoxide Dismutase from Mycobacterium Tuberculosis. X-Ray Structure Analysis of Site-Directed Mutants
Eur.J.Biochem., 251, 1998
1GN2
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S123C mutant of the iron-superoxide dismutase from Mycobacterium tuberculosis.
分子名称: FE (III) ION, SUPEROXIDE DISMUTASE
著者Bunting, K.A, Cooper, J.B, Tickle, I.J, Young, D.B.
登録日2001-10-02
公開日2001-10-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Engineering of an Intersubunit Disulfide Bridge in the Iron-Superoxide Dismutase of Mycobacterium Tuberculosis.
Arch.Biochem.Biophys., 397, 2002
1GN3
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H145Q mutant of Mycobacterium tuberculosis iron-superoxide dismutase.
分子名称: FE (III) ION, SUPEROXIDE DISMUTASE
著者Bunting, K.A, Cooper, J.B, Badasso, M.O, Tickle, I.J, Newton, M, Wood, S.P, Zhang, Y, Young, D.B.
登録日2001-10-02
公開日2001-10-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Engineering a Change in the Metal-Ion Specificity of the Iron-Depedent Superoxide Dismutase from Mycobacterium Tuberculosis. X-Ray Structure Analysis of Site-Directed Mutants.
Eur.J.Biochem., 251, 1998
1P3H
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BU of 1p3h by Molmil
Crystal Structure of the Mycobacterium tuberculosis chaperonin 10 tetradecamer
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 10 kDa chaperonin, CALCIUM ION
著者Roberts, M.M, Coker, A.R, Fossati, G, Mascagni, P, Coates, A.R.M, Wood, S.P, TB Structural Genomics Consortium (TBSGC)
登録日2003-04-17
公開日2003-07-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mycobacterium tuberculosis chaperonin 10 heptamers self-associate through their biologically active loops
J.BACTERIOL., 185, 2003
1V0M
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Xylanase Xyn10a from Streptomyces lividans in complex with xylobio-deoxynojirimycin at pH 7.5
分子名称: ENDO-1,4-BETA-XYLANASE A, IMIDAZOLE, PIPERIDINE-3,4,5-TRIOL, ...
著者Gloster, T.M, Williams, S.J, Roberts, S, Tarling, C.A, Wicki, J, Withers, S.G, Davies, G.J.
登録日2004-03-31
公開日2004-08-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Atomic Resolution Analyses of the Binding of Xylobiose-Derived Deoxynojirimycin and Isofagomine to Xylanase Xyn10A
Chem.Commun.(Camb.), 16, 2004
1V0K
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Xylanase Xyn10A from Streptomyces lividans in complex with xylobio-deoxynojirimycin at pH 5.8
分子名称: ENDO-1,4-BETA-XYLANASE A, PIPERIDINE-3,4,5-TRIOL, beta-D-xylopyranose
著者Gloster, T.M, Williams, S.J, Roberts, S, Tarling, C.A, Wicki S, J, Withers, G, Davies, G.J.
登録日2004-03-31
公開日2004-08-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Atomic Resolution Analyses of the Binding of Xylobiose-Derived Deoxynojirimycin and Isofagomine to Xylanase Xyn10A
Chem.Commun.(Camb.), 16, 2004
2QJ3
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BU of 2qj3 by Molmil
Mycobacterium tuberculosis FabD
分子名称: Malonyl CoA-acyl carrier protein transacylase, NICKEL (II) ION
著者Ghadbane, H, Brown, A.K, Kremer, L, Besra, G.S, Futterer, K.
登録日2007-07-06
公開日2007-09-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT).
Acta Crystallogr.,Sect.F, 63, 2007
7W58
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Crystal structure of acyl-carrier protein synthase from Mycobacterium smegmatis
分子名称: 1,2-ETHANEDIOL, 4'-phosphopantetheinyl transferase, NICKEL (II) ION
著者Yadav, S, Bhatia, I, Biswal, B.K.
登録日2021-11-29
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Identification, structure determination and analysis of Mycobacterium smegmatis acyl-carrier protein synthase (AcpS) crystallized serendipitously.
Acta Crystallogr.,Sect.F, 78, 2022
1Z9W
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BU of 1z9w by Molmil
Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis
分子名称: Dihydroneopterin aldolase
著者Goulding, C.W, Apostol, M.I, Sawaya, M.R, Philips, M, Parseghian, A, Eisenberg, D, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-04-05
公開日2005-04-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
8QKK
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Cryo-EM structure of MmpL3 from Mycobacterium smegmatis reconstituted into peptidiscs
分子名称: Trehalose monomycolate exporter MmpL3
著者Couston, J, Guo, Z, Wang, K, Gourdon, P.E, Blaise, M.
登録日2023-09-15
公開日2023-11-15
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Cryo-EM structure of the trehalose monomycolate transporter, MmpL3, reconstituted into peptidiscs.
Curr Res Struct Biol, 6, 2023
1SFR
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BU of 1sfr by Molmil
Crystal Structure of the Mycobacterium tuberculosis Antigen 85A Protein
分子名称: Antigen 85-A
著者Ronning, D.R, Vissa, V, Besra, G.S, Belisle, J.T, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2004-02-20
公開日2004-07-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mycobacterium tuberculosis Antigen 85A and 85C Structures Confirm Binding Orientation and Conserved Substrate Specificity
J.Biol.Chem., 279, 2004
4KB5
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Crystal structure of MycP1 from Mycobacterium smegmatis
分子名称: GLYCEROL, Membrane-anchored mycosin mycp1
著者Sun, D.M, He, Y, Tian, C.L.
登録日2013-04-23
公開日2014-02-05
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stability.
Protein Cell, 4, 2013
7E51
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Structure of PEP bound Enolase from Mycobacterium tuberculosis
分子名称: Enolase, MAGNESIUM ION, PHOSPHOENOLPYRUVATE
著者Bose, S, Vinothkumar, K.R.
登録日2021-02-16
公開日2022-02-16
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural snapshots of Mycobacterium tuberculosis enolase reveal dual mode of 2PG binding and its implication in enzyme catalysis.
Iucrj, 10, 2023
7ENS
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BU of 7ens by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Indolmycin and ATP
分子名称: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-04-19
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7E4X
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BU of 7e4x by Molmil
Structure of Enolase from Mycobacterium tuberculosis
分子名称: Enolase
著者Bose, S, Vinothkumar, K.R.
登録日2021-02-15
公開日2022-02-16
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structural snapshots of Mycobacterium tuberculosis enolase reveal dual mode of 2PG binding and its implication in enzyme catalysis.
Iucrj, 10, 2023
2M4V
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BU of 2m4v by Molmil
Mycobacterium tuberculosis RNA polymerase binding protein A (RbpA) and its interactions with sigma factors
分子名称: Putative uncharacterized protein
著者Bortoluzzi, A, Muskett, F.W, Waters, L.C, Addis, P.W, Rieck, B, Munder, T, Schleier, S, Forti, F, Ghisotti, D, Carr, M.D, O'Hare, H.M.
登録日2013-02-11
公開日2013-04-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Mycobacterium tuberculosis RNA polymerase-binding protein A (RbpA) and its interactions with sigma factors.
J.Biol.Chem., 288, 2013
4J94
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Crystal structure of MycP1 from the ESX-1 type VII secretion system
分子名称: Membrane-anchored mycosin mycp1
著者Solomonson, M, Wasney, G.A, Watanabe, N, Gruninger, R.J, Prehna, G, Strynadka, N.C.J.
登録日2013-02-15
公開日2013-05-01
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.857 Å)
主引用文献Structure of the Mycosin-1 Protease from the Mycobacterial ESX-1 Protein Type VII Secretion System.
J.Biol.Chem., 288, 2013
2CIG
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Dihydrofolate reductase from Mycobacterium tuberculosis inhibited by the acyclic 4R isomer of INH-NADP a derivative of the prodrug isoniazid.
分子名称: (4R)-ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE, DIHYDROFOLATE REDUCTASE, GLYCEROL, ...
著者Argyrou, A, Vetting, M.W, Aladegbami, B, Blanchard, J.S.
登録日2006-03-20
公開日2006-04-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mycobacterium Tuberculosis Dihydrofolate Reductase is a Target for Isoniazid
Nat.Struct.Mol.Biol., 13, 2006
4HVL
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Structure of a serine protease MycP1, an essential component of the type VII (ESX-1) secretion system
分子名称: ACETATE ION, CHLORIDE ION, IMIDAZOLE, ...
著者Korotkov, K.V, Evans, T.J.
登録日2012-11-06
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis.
J.Struct.Biol., 184, 2013
4KPG
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BU of 4kpg by Molmil
Crystal structure of MycP1 from the ESX-1 type VII secretion system
分子名称: Membrane-anchored mycosin mycp1
著者Solomonson, M, Wasney, G.A, Watanabe, N, Gruninger, R.J, Prehna, G, Strynadka, N.C.J.
登録日2013-05-13
公開日2013-05-22
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.148 Å)
主引用文献Structure of the Mycosin-1 Protease from the Mycobacterial ESX-1 Protein Type VII Secretion System.
J.Biol.Chem., 288, 2013
5ECV
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BU of 5ecv by Molmil
Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-hydroxy-4-(4-methyl-1H-indol-5-yl)-4-oxobut-2-enoic acid
分子名称: (~{Z})-4-(4-methyl-1~{H}-indol-5-yl)-2-oxidanyl-4-oxidanylidene-but-2-enoic acid, MAGNESIUM ION, Malate synthase G
著者Krieger, I.V, Huang, H.-L, Sacchettini, J.C.
登録日2015-10-20
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.085 Å)
主引用文献Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange.
J. Biol. Chem., 291, 2016
2NC8
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BU of 2nc8 by Molmil
NMR structure of the Mycobacterium tuberculosis LppM (Rv2171) protein folded domain
分子名称: Lipoprotein LppM
著者Barthe, P, Cohen-Gonsaud, M.
登録日2016-03-22
公開日2016-09-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization.
Structure, 24, 2016
2E3J
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The crystal structure of epoxide hydrolase B (Rv1938) from mycobacterium tuberculosis at 2.1 angstrom
分子名称: ACETATE ION, EPOXIDE HYDROLASE EPHB
著者Biswal, B.K, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2006-11-27
公開日2007-12-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor.
J.Mol.Biol., 381, 2008
1IDR
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BU of 1idr by Molmil
CRYSTAL STRUCTURE OF THE TRUNCATED-HEMOGLOBIN-N FROM MYCOBACTERIUM TUBERCULOSIS
分子名称: HEMOGLOBIN HBN, OXYGEN MOLECULE, PHOSPHATE ION, ...
著者Milani, M, Pesce, A, Ascenzi, P, Guertin, M, Bolognesi, M.
登録日2001-04-05
公開日2001-08-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mycobacterium tuberculosis hemoglobin N displays a protein tunnel suited for O2 diffusion to the heme.
EMBO J., 20, 2001
7CL5
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The crystal structure of KanJ in complex with kanamycin B and N-oxalylglycine
分子名称: (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, Kanamycin B dioxygenase, N-OXALYLGLYCINE, ...
著者Kitayama, Y, Miyanaga, A, Kudo, F, Eguchi, T.
登録日2020-07-20
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Stepwise Post-glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis.
Chembiochem, 22, 2021

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