2V1U
| STRUCTURE OF THE AEROPYRUM PERNIX ORC1 PROTEIN IN COMPLEX WITH DNA | 分子名称: | 5'-D(*AP*CP*CP*CP*CP*TP*CP*CP*GP*TP *TP*TP*CP*CP*TP*GP*TP*GP*GP*AP*GP*A)-3', 5'-D(*TP*CP*TP*CP*CP*AP*CP*AP*GP*GP *AP*AP*AP*CP*GP*GP*AP*GP*GP*GP*GP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Gaudier, M, Schuwirth, B.S, Westcott, S.L, Wigley, D.B. | 登録日 | 2007-05-30 | 公開日 | 2007-09-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Basis of DNA Replication Origin Recognition by an Orc Protein. Science, 317, 2007
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1FNN
| CRYSTAL STRUCTURE OF CDC6P FROM PYROBACULUM AEROPHILUM | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CELL DIVISION CONTROL PROTEIN 6, MAGNESIUM ION | 著者 | Liu, J, Smith, C.L, DeRyckere, D, DeAngelis, K, Martin, G.S, Berger, J.M. | 登録日 | 2000-08-22 | 公開日 | 2000-10-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control. Mol.Cell, 6, 2000
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2QBY
| Crystal structure of a heterodimer of Cdc6/Orc1 initiators bound to origin DNA (from S. solfataricus) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 6 homolog 1, Cell division control protein 6 homolog 3, ... | 著者 | Cunningham Dueber, E.L, Corn, J.E, Bell, S.D, Berger, J.M. | 登録日 | 2007-06-18 | 公開日 | 2007-09-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Replication origin recognition and deformation by a heterodimeric archaeal Orc1 complex. Science, 317, 2007
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1W5T
| Structure of the Aeropyrum Pernix ORC2 protein (ADPNP-ADP complexes) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ORC2, ... | 著者 | Singleton, M.R, Morales, R, Grainge, I, Cook, N, Isupov, M.N, Wigley, D.B. | 登録日 | 2004-08-09 | 公開日 | 2004-10-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Conformational Changes Induced by Nucleotide Binding in Cdc6/Orc from Aeropyrum Pernix J.Mol.Biol., 343, 2004
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1W5S
| Structure of the Aeropyrum Pernix ORC2 protein (ADP form) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORC2, SULFATE ION | 著者 | Singleton, M.R, Morales, R, Grainge, I, Cook, N, Isupov, M.N, Wigley, D.B. | 登録日 | 2004-08-09 | 公開日 | 2004-10-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Conformational Changes Induced by Nucleotide Binding in Cdc6/Orc from Aeropyrum Pernix J.Mol.Biol., 343, 2004
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4XGC
| Crystal structure of the eukaryotic origin recognition complex | 分子名称: | CHLORIDE ION, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | 著者 | Bleichert, F, Botchan, M.R, Berger, J.M. | 登録日 | 2014-12-30 | 公開日 | 2015-04-01 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structure of the eukaryotic origin recognition complex. Nature, 519, 2015
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7MCA
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7CTF
| Human origin recognition complex 1-5 State II | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | 著者 | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | 登録日 | 2020-08-18 | 公開日 | 2021-01-06 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020
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7CTG
| Human Origin Recognition Complex, ORC1-5 State I | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | 著者 | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | 登録日 | 2020-08-18 | 公開日 | 2021-01-06 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020
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6WGG
| Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) | 分子名称: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (41-MER), ... | 著者 | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | 登録日 | 2020-04-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | 主引用文献 | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WGC
| Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) | 分子名称: | Cell division control protein 6, DNA (41-MER), DNA replication licensing factor MCM3, ... | 著者 | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | 登録日 | 2020-04-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
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5UJM
| Structure of the active form of human Origin Recognition Complex and its ATPase motor module | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ... | 著者 | Tocilj, A, On, K, Yuan, Z, Sun, J, Elkayam, E, Li, H, Stillman, B, Joshua-Tor, L. | 登録日 | 2017-01-18 | 公開日 | 2017-02-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (18 Å) | 主引用文献 | Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6, 2017
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5UJ7
| Structure of the active form of human Origin Recognition Complex ATPase motor module, complex subunitS 1, 4, 5 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ... | 著者 | Tocilj, A, Elkayam, E, On, K.F, Joshua-Tor, L. | 登録日 | 2017-01-17 | 公開日 | 2017-02-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.394 Å) | 主引用文献 | Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6, 2017
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6WGI
| Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution | 分子名称: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ... | 著者 | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | 登録日 | 2020-04-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
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5V8F
| Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1 | 分子名称: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (39-MER), ... | 著者 | Yuan, Z, Riera, A, Bai, L, Sun, J, Spanos, C, Chen, Z.A, Barbon, M, Rappsilber, J, Stillman, B, Speck, C, Li, H. | 登録日 | 2017-03-21 | 公開日 | 2017-05-10 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1. Nat. Struct. Mol. Biol., 24, 2017
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7TJK
| S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with docked Orc6 N-terminal domain | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | 著者 | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | 登録日 | 2022-01-16 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
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7TJJ
| S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with docked Orc6 N-terminal domain | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | 著者 | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | 登録日 | 2022-01-16 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
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7TJI
| S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with flexible Orc6 N-terminal domain | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | 著者 | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | 登録日 | 2022-01-16 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
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7TJH
| S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with flexible Orc6 N-terminal domain | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | 著者 | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | 登録日 | 2022-01-16 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
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7JPP
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7JK4
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7JGS
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7JPR
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7JPO
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7JPS
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