2JV2
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1CR5
| N-TERMINAL DOMAIN OF SEC18P | 分子名称: | 1-ETHYL-PYRROLIDINE-2,5-DIONE, SEC18P (RESIDUES 22 - 210) | 著者 | Babor, S.M, Fass, D. | 登録日 | 1999-08-13 | 公開日 | 1999-12-22 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the Sec18p N-terminal domain. Proc.Natl.Acad.Sci.USA, 96, 1999
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4UZR
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2M3X
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9BOQ
| Human p97/VCP structure with a triazole inhibitor (NSC799462/dodecamer) | 分子名称: | 3-(2,6-difluoro-4-{[(4P)-5-{[(2S)-hexan-2-yl]sulfanyl}-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl (1-methylpiperidin-4-yl)carbamate, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Nandi, P, DeVore, K, Chiu, P.-L. | 登録日 | 2024-05-05 | 公開日 | 2024-08-21 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Mechanism of allosteric inhibition of human p97/VCP ATPase and its disease mutant by triazole inhibitors. Commun Chem, 7, 2024
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5X4L
| Crystal structure of the UBX domain of human UBXD7 in complex with p97 N domain | 分子名称: | Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 7 | 著者 | Jiang, T, Li, Z, Wang, Y, Xu, M. | 登録日 | 2017-02-13 | 公開日 | 2017-03-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase Biochem. Biophys. Res. Commun., 486, 2017
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7OAT
| Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Petrovic, S, Heinemann, U, Roske, Y. | 登録日 | 2021-04-20 | 公開日 | 2022-08-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.995 Å) | 主引用文献 | Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D. Proc.Natl.Acad.Sci.USA, 120, 2023
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5IFW
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8B5R
| p97-p37-SPI substrate complex | 分子名称: | I3 sequence being threaded through the p97 channel, Protein phosphatase 1 regulatory subunit 7, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, ... | 著者 | van den Boom, J, Marini, G, Meyer, H, Saibil, H. | 登録日 | 2022-09-24 | 公開日 | 2023-06-07 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structural basis of ubiquitin-independent PP1 complex disassembly by p97. Embo J., 42, 2023
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2PJH
| Strctural Model of the p97 N domain- npl4 UBD complex | 分子名称: | Nuclear protein localization protein 4 homolog, Transitional endoplasmic reticulum ATPase | 著者 | Isaacson, R, Pye, V.E, Simpson, S, Meyer, H.H, Zhang, X, Freemont, P. | 登録日 | 2007-04-16 | 公開日 | 2007-05-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Detailed structural insights into the p97-Npl4-Ufd1 interface. J.Biol.Chem., 282, 2007
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6CHS
| Cdc48-Npl4 complex in the presence of ATP-gamma-S | 分子名称: | MAGNESIUM ION, Npl4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Kim, K.H, Bodnar, N.O, Walz, T, Rapoport, T.A. | 登録日 | 2018-02-22 | 公開日 | 2018-07-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4. Nat. Struct. Mol. Biol., 25, 2018
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4RV0
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1S3S
| Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin containing protein) (VCP) [Contains: Valosin], p47 protein | 著者 | Dreveny, I, Kondo, H, Uchiyama, K, Shaw, A, Zhang, X, Freemont, P.S. | 登録日 | 2004-01-14 | 公開日 | 2004-03-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47. Embo J., 23, 2004
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3QC8
| Crystal Structure of FAF1 UBX Domain In Complex with p97/VCP N Domain Reveals The Conserved FcisP Touch-Turn Motif of UBX Domain Suffering Conformational Change | 分子名称: | FAS-associated factor 1, Transitional endoplasmic reticulum ATPase | 著者 | Kim, K.H, Kang, W, Suh, S.W, Yang, J.K. | 登録日 | 2011-01-15 | 公開日 | 2011-07-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of FAF1 UBX domain in complex with p97/VCP N domain reveals a conformational change in the conserved FcisP touch-turn motif of UBX domain Proteins, 79, 2011
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3QQ7
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3QQ8
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5IFS
| Quantitative interaction mapping reveals an extended ubiquitin regulatory domain in ASPL that disrupts functional p97 hexamers and induces cell death | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Roske, Y, Arumughan, A, Heinemann, U, Wanker, E. | 登録日 | 2016-02-26 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers. Nat Commun, 7, 2016
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3QWZ
| Crystal structure of FAF1 UBX-p97N-domain complex | 分子名称: | FAS-associated factor 1, Transitional endoplasmic reticulum ATPase | 著者 | Park, J.K, Jeon, H, Lee, J.J, Kim, K.H, Lee, K.J, Kim, E.E. | 登録日 | 2011-02-28 | 公開日 | 2012-05-09 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Dissection of the interaction between FAF1 UBX and p97 To be Published
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1QCS
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6HD0
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1QDN
| AMINO TERMINAL DOMAIN OF THE N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF) | 分子名称: | BETA-MERCAPTOETHANOL, PROTEIN (N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF)), SULFATE ION | 著者 | May, A.P, Misura, K.M.S, Whiteheart, S.W, Weis, W.I. | 登録日 | 1999-05-21 | 公開日 | 1999-06-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the amino-terminal domain of N-ethylmaleimide-sensitive fusion protein. Nat.Cell Biol., 1, 1999
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6HD3
| Common mode of remodeling AAA ATPases p97/CDC48 by their disassembly cofactors ASPL/PUX1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 48 homolog A, PHOSPHATE ION | 著者 | Heinemann, U, Roske, Y, Banchenko, S, Arumughan, A, Petrovic, S. | 登録日 | 2018-08-17 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Common Mode of Remodeling AAA ATPases p97/CDC48 by Their Disassembling Cofactors ASPL/PUX1. Structure, 27, 2019
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8KG2
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8OOI
| Full composite cryo-EM map of p97/VCP in ADP.Pi state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Cheng, T.C, Sakata, E, Schuetz, A.K. | 登録日 | 2023-04-05 | 公開日 | 2024-01-31 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | 主引用文献 | Characterizing ATP processing by the AAA+ protein p97 at the atomic level. Nat.Chem., 16, 2024
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5KIW
| p97 ND1-L198W in complex with VIMP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Selenoprotein S, ... | 著者 | Tang, W.K, Xia, D. | 登録日 | 2016-06-17 | 公開日 | 2018-03-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | 主引用文献 | Structural basis for nucleotide-modulated p97 association with the ER membrane. Cell Discov, 3, 2017
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