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PDB: 149 件
7DG7
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DPBB domain of VCP-like ATPase from Methanopyrus kandleri
分子名称: ATPase of the AAA+ class, IMIDAZOLE, ZINC ION
著者Yagi, S, Tagami, S.
登録日2020-11-11
公開日2021-09-29
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.604 Å)
主引用文献Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.
J.Am.Chem.Soc., 143, 2021
7DBO
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BU of 7dbo by Molmil
DPBB domain of VCP-like ATPase from Thermoplasma acidophilum
分子名称: SULFATE ION, VCP-like ATPase
著者Yagi, S, Tagami, S.
登録日2020-10-21
公開日2021-09-29
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.
J.Am.Chem.Soc., 143, 2021
7DG9
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DPBB domain of VCP-like ATPase from Aeropyrum pernix
分子名称: Cell division control protein 48, AAA family, ZINC ION
著者Yagi, S, Tagami, S.
登録日2020-11-11
公開日2021-09-29
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.
J.Am.Chem.Soc., 143, 2021
2PJH
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BU of 2pjh by Molmil
Strctural Model of the p97 N domain- npl4 UBD complex
分子名称: Nuclear protein localization protein 4 homolog, Transitional endoplasmic reticulum ATPase
著者Isaacson, R, Pye, V.E, Simpson, S, Meyer, H.H, Zhang, X, Freemont, P.
登録日2007-04-16
公開日2007-05-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Detailed structural insights into the p97-Npl4-Ufd1 interface.
J.Biol.Chem., 282, 2007
4RV0
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BU of 4rv0 by Molmil
Crystal structure of TN complex
分子名称: Nuclear protein localization protein 4 homolog, SULFATE ION, Transitional endoplasmic reticulum ATPase TER94
著者Hao, Q, Jiao, S, Shi, Z.B, Zhou, Z.C.
登録日2014-11-23
公開日2015-11-25
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Crystal structure of TN complex
To be Published
3QQ7
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BU of 3qq7 by Molmil
Crystal Structure of the p97 N-terminal domain
分子名称: CHLORIDE ION, COBALT (II) ION, GLYCEROL, ...
著者Haenzelmann, P, Schindelin, H.
登録日2011-02-15
公開日2011-06-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Hierarchical Binding of Cofactors to the AAA ATPase p97.
Structure, 19, 2011
1QCS
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BU of 1qcs by Molmil
N-TERMINAL DOMAIN OF N-ETHYLMALEIMIDE SENSITIVE FACTOR (NSF)
分子名称: N-ETHYLMALEIMIDE SENSITIVE FACTOR (NSF-N), SULFATE ION
著者Yu, R.C, Jahn, R, Brunger, A.T.
登録日1999-05-14
公開日1999-05-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献NSF N-terminal domain crystal structure: models of NSF function.
Mol.Cell, 4, 1999
1QDN
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BU of 1qdn by Molmil
AMINO TERMINAL DOMAIN OF THE N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF)
分子名称: BETA-MERCAPTOETHANOL, PROTEIN (N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF)), SULFATE ION
著者May, A.P, Misura, K.M.S, Whiteheart, S.W, Weis, W.I.
登録日1999-05-21
公開日1999-06-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the amino-terminal domain of N-ethylmaleimide-sensitive fusion protein.
Nat.Cell Biol., 1, 1999
1CZ5
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BU of 1cz5 by Molmil
NMR STRUCTURE OF VAT-N: THE N-TERMINAL DOMAIN OF VAT (VCP-LIKE ATPASE OF THERMOPLASMA)
分子名称: VCP-LIKE ATPASE
著者Coles, M, Diercks, T, Liermann, J, Groeger, A, Rockel, B, Baumeister, W, Koretke, K, Lupas, A, Peters, J, Kessler, H.
登録日1999-09-01
公開日1999-10-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of VAT-N reveals a 'missing link' in the evolution of complex enzymes from a simple betaalphabetabeta element.
Curr.Biol., 9, 1999
3TIW
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BU of 3tiw by Molmil
Crystal structure of p97N in complex with the C-terminus of gp78
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase AMFR, Transitional endoplasmic reticulum ATPase
著者Haenzelmann, P, Schindelin, H.
登録日2011-08-22
公開日2011-09-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97.
J.Biol.Chem., 286, 2011
1CZ4
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BU of 1cz4 by Molmil
NMR STRUCTURE OF VAT-N: THE N-TERMINAL DOMAIN OF VAT (VCP-LIKE ATPASE OF THERMOPLASMA)
分子名称: VCP-LIKE ATPASE
著者Coles, M, Diercks, T, Liermann, J, Groeger, A, Rockel, B, Baumeister, W, Koretke, K, Lupas, A, Peters, J, Kessler, H.
登録日1999-09-01
公開日1999-10-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of VAT-N reveals a 'missing link' in the evolution of complex enzymes from a simple betaalphabetabeta element.
Curr.Biol., 9, 1999
4KDL
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BU of 4kdl by Molmil
Crystal structure of p97/VCP N in complex with OTU1 UBXL
分子名称: Transitional endoplasmic reticulum ATPase, Ubiquitin thioesterase OTU1
著者Kim, S.J, Kim, E.E.
登録日2013-04-25
公開日2014-03-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP).
J.Biol.Chem., 289, 2014
4KDI
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BU of 4kdi by Molmil
Crystal structure of p97/VCP N in complex with OTU1 UBXL
分子名称: Transitional endoplasmic reticulum ATPase, Ubiquitin thioesterase OTU1
著者Kim, S.J, Kim, E.E.
登録日2013-04-25
公開日2014-03-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP).
J.Biol.Chem., 289, 2014
5B6C
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BU of 5b6c by Molmil
Structural Details of Ufd1 binding to p97
分子名称: Peptide from Ubiquitin fusion degradation protein 1 homolog, Transitional endoplasmic reticulum ATPase
著者Le, L.T.M, Yang, J.K.
登録日2016-05-26
公開日2017-01-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural Details of Ufd1 Binding to p97 and Their Functional Implications in ER-Associated Degradation
PLoS ONE, 11, 2016
5GLF
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BU of 5glf by Molmil
Structural insights into the interaction of p97 N-terminal domain and SHP motif in Derlin-1 rhomboid pseudoprotease
分子名称: Derlin-1, Transitional endoplasmic reticulum ATPase
著者Lim, J.J, Lee, Y, Yoon, S.Y, Ly, T.T, Kang, J.Y, Youn, H.-S, An, J.Y, Lee, J.-G, Park, K.R, Kim, T.G, Yang, J.K, Jun, Y, Eom, S.H.
登録日2016-07-11
公開日2016-11-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural insights into the interaction of human p97 N-terminal domain and SHP motif in Derlin-1 rhomboid pseudoprotease.
FEBS Lett., 590, 2016
5EPP
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BU of 5epp by Molmil
Structural Insights into the Interaction of p97 N-terminus Domain and VBM Motif in Rhomboid Protease, RHBDL4
分子名称: Rhomboid-related protein 4, Transitional endoplasmic reticulum ATPase
著者Lim, J.J, Lee, Y, Ly, T.T, Kang, J.Y, Lee, J.-G, An, J.Y, Youn, H.-S, Park, K.R, Kim, T.G, Yang, J.K, Jun, Y, Eom, S.H.
登録日2015-11-12
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural insights into the interaction of p97 N-terminus domain and VBM in rhomboid protease, RHBDL4.
Biochem.J., 473, 2016
9BOQ
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BU of 9boq by Molmil
Human p97/VCP structure with a triazole inhibitor (NSC799462/dodecamer)
分子名称: 3-(2,6-difluoro-4-{[(4P)-5-{[(2S)-hexan-2-yl]sulfanyl}-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl (1-methylpiperidin-4-yl)carbamate, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Nandi, P, DeVore, K, Chiu, P.-L.
登録日2024-05-05
公開日2024-08-21
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Mechanism of allosteric inhibition of human p97/VCP ATPase and its disease mutant by triazole inhibitors.
Commun Chem, 7, 2024
5X4L
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BU of 5x4l by Molmil
Crystal structure of the UBX domain of human UBXD7 in complex with p97 N domain
分子名称: Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 7
著者Jiang, T, Li, Z, Wang, Y, Xu, M.
登録日2017-02-13
公開日2017-03-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase
Biochem. Biophys. Res. Commun., 486, 2017
7OAT
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BU of 7oat by Molmil
Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Petrovic, S, Heinemann, U, Roske, Y.
登録日2021-04-20
公開日2022-08-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.995 Å)
主引用文献Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
Proc.Natl.Acad.Sci.USA, 120, 2023
5IFW
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BU of 5ifw by Molmil
Quantitative interaction mapping reveals an extended ubiquitin regulatory domain in ASPL that disrupts functional p97 hexamers and induces cell death
分子名称: ADENOSINE-5'-DIPHOSPHATE, Tether containing UBX domain for GLUT4, Transitional endoplasmic reticulum ATPase
著者Roske, Y, Heinemann, U.
登録日2016-02-26
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Nat Commun, 7, 2016
8B5R
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BU of 8b5r by Molmil
p97-p37-SPI substrate complex
分子名称: I3 sequence being threaded through the p97 channel, Protein phosphatase 1 regulatory subunit 7, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, ...
著者van den Boom, J, Marini, G, Meyer, H, Saibil, H.
登録日2022-09-24
公開日2023-06-07
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Structural basis of ubiquitin-independent PP1 complex disassembly by p97.
Embo J., 42, 2023
6CHS
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BU of 6chs by Molmil
Cdc48-Npl4 complex in the presence of ATP-gamma-S
分子名称: MAGNESIUM ION, Npl4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Kim, K.H, Bodnar, N.O, Walz, T, Rapoport, T.A.
登録日2018-02-22
公開日2018-07-04
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4.
Nat. Struct. Mol. Biol., 25, 2018
1S3S
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BU of 1s3s by Molmil
Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin containing protein) (VCP) [Contains: Valosin], p47 protein
著者Dreveny, I, Kondo, H, Uchiyama, K, Shaw, A, Zhang, X, Freemont, P.S.
登録日2004-01-14
公開日2004-03-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47.
Embo J., 23, 2004
3QC8
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BU of 3qc8 by Molmil
Crystal Structure of FAF1 UBX Domain In Complex with p97/VCP N Domain Reveals The Conserved FcisP Touch-Turn Motif of UBX Domain Suffering Conformational Change
分子名称: FAS-associated factor 1, Transitional endoplasmic reticulum ATPase
著者Kim, K.H, Kang, W, Suh, S.W, Yang, J.K.
登録日2011-01-15
公開日2011-07-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of FAF1 UBX domain in complex with p97/VCP N domain reveals a conformational change in the conserved FcisP touch-turn motif of UBX domain
Proteins, 79, 2011
3QQ8
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BU of 3qq8 by Molmil
Crystal structure of p97-N in complex with FAF1-UBX
分子名称: CHLORIDE ION, FAS-associated factor 1, Transitional endoplasmic reticulum ATPase
著者Haenzelmann, P, Schindelin, H.
登録日2011-02-15
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Hierarchical Binding of Cofactors to the AAA ATPase p97.
Structure, 19, 2011

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