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PDB: 89 件
3V98
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S663D Stable-5-LOX
分子名称: Arachidonate 5-lipoxygenase, FE (II) ION
著者Gilbert, N.C, Rui, Z, Neau, D.B, Waight, M, Bartlett, S.G, Boeglin, W.E, Brash, A.R, Newcomer, M.E.
登録日2011-12-23
公開日2012-05-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.
Faseb J., 26, 2012
5EEO
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soybean lipoxygenase(L1)-T756R
分子名称: FE (II) ION, Seed linoleate 13S-lipoxygenase-1
著者Mikami, B, Nagaya, T, Hioki, Y.
登録日2015-10-23
公開日2015-11-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structural basis for specificity in lipoxygenase catalysis
To Be Published
1ETH
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BU of 1eth by Molmil
TRIACYLGLYCEROL LIPASE/COLIPASE COMPLEX
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, BETA-MERCAPTOETHANOL, CALCIUM ION, ...
著者Hermoso, J, Pignol, D, Kerfelec, B, Crenon, I, Chapus, C, Fontecilla-Camps, J.C.
登録日1995-09-13
公開日1996-12-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Lipase activation by nonionic detergents. The crystal structure of the porcine lipase-colipase-tetraethylene glycol monooctyl ether complex.
J.Biol.Chem., 271, 1996
6A70
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BU of 6a70 by Molmil
Structure of the human PKD1/PKD2 complex
分子名称: Polycystin-1, Polycystin-2
著者Su, Q, Hu, F, Ge, X, Lei, J, Yu, S, Wang, T, Zhou, Q, Mei, C, Shi, Y.
登録日2018-06-29
公開日2018-08-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of the human PKD1-PKD2 complex.
Science, 361, 2018
3CWZ
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BU of 3cwz by Molmil
Structure of RAB6(GTP)-R6IP1 complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab6-interacting protein 1, ...
著者Recacha, R, Houdusse, A, Goud, B, Khan, A.R.
登録日2008-04-23
公開日2008-11-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain.
Structure, 17, 2009
8I6Y
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Crystal structure of Arabidopsis thaliana LOX1
分子名称: FE (III) ION, Linoleate 9S-lipoxygenase 1
著者Liu, X, Liu, L.
登録日2023-01-30
公開日2024-02-07
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献UV-B light signal mediates stomatal closure by activating the 9-lipoxygenase pathway
To Be Published
4WHA
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BU of 4wha by Molmil
Lipoxygenase-1 (soybean) L546A/L754A mutant
分子名称: 1,2-ETHANEDIOL, ACETATE ION, FE (III) ION, ...
著者Scouras, A.D, Carr, C.A.M, Hu, S, Klinman, J.P.
登録日2014-09-21
公開日2014-11-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Extremely elevated room-temperature kinetic isotope effects quantify the critical role of barrier width in enzymatic C-H activation.
J.Am.Chem.Soc., 136, 2014
6U7M
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BU of 6u7m by Molmil
Cryo-EM Structure of Helical Lipoprotein Lipase
分子名称: Lipoprotein lipase
著者Gunn, K.H, Wang, F, Egelman, E.H, Neher, S.B.
登録日2019-09-03
公開日2020-04-08
最終更新日2020-05-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage.
Proc.Natl.Acad.Sci.USA, 117, 2020
7SOJ
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Structure of V750A Soybean Lipoxygenase at 277K
分子名称: FE (III) ION, Lipoxygenase
著者Gee, C.L, Offenbacher, A.R, Hu, S.
登録日2021-10-31
公開日2022-11-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase.
Proc.Natl.Acad.Sci.USA, 120, 2023
6E7K
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Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride hydrolysis
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Birrane, G, Meiyappan, M.
登録日2018-07-26
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
7LAF
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15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor
分子名称: 3-{[(4-methylphenyl)methyl]sulfanyl}-1-phenyl-1H-1,2,4-triazole, MANGANESE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX15B
著者Newcomer, M.E, Gilbert, N.C, Neau, D.B.
登録日2021-01-06
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2.
Bioorg.Med.Chem., 46, 2021
4QWT
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Anaerobic crystal structure of delta413-417:GS LOX in complex with arachidonate
分子名称: ACETATE ION, ARACHIDONIC ACID, Allene oxide synthase-lipoxygenase protein, ...
著者Neau, D.B, Newcomer, M.E.
登録日2014-07-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Crystal Structure of a Lipoxygenase in Complex with Substrate: THE ARACHIDONIC ACID-BINDING SITE OF 8R-LIPOXYGENASE.
J.Biol.Chem., 289, 2014
4WFO
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BU of 4wfo by Molmil
manganese-substituted soybean lipoxygenase-1
分子名称: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ...
著者Carr, C.A.M, Scouras, A.D, Klinman, J.P.
登録日2014-09-16
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Direct detection of active-site geometries in soybean lipoxygenase-1 by ENDOR
To Be Published
2FNQ
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BU of 2fnq by Molmil
Insights from the X-ray crystal structure of coral 8R-lipoxygenase: calcium activation via A C2-like domain and a structural basis of product chirality
分子名称: Allene oxide synthase-lipoxygenase protein, CALCIUM ION, FE (II) ION
著者Oldham, M.L, Brash, A.R, Newcomer, M.E.
登録日2006-01-11
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Insights from the X-ray crystal structure of coral 8R-lipoxygenase: calcium activation via a C2-like domain and a structural basis of product chirality.
J.Biol.Chem., 280, 2005
8ERL
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BU of 8erl by Molmil
CryoEM Structure of Lipoprotein Lipase Dimer
分子名称: Lipoprotein lipase
著者Gunn, K.H, Neher, S.B.
登録日2022-10-12
公開日2023-05-03
最終更新日2023-05-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure of dimeric lipoprotein lipase reveals a pore adjacent to the active site.
Nat Commun, 14, 2023
4NRE
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BU of 4nre by Molmil
The structure of human 15-lipoxygenase-2 with a substrate mimic
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Arachidonate 15-lipoxygenase B, CALCIUM ION, ...
著者Kobe, M.J, Neau, D.B, Mitchell, C.E, Bartlett, S.G, Newcomer, M.E.
登録日2013-11-26
公開日2014-02-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献The structure of human 15-lipoxygenase-2 with a substrate mimic.
J.Biol.Chem., 289, 2014
1W52
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BU of 1w52 by Molmil
Crystal structure of a proteolyzed form of pancreatic lipase related protein 2 from horse
分子名称: CALCIUM ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, PANCREATIC LIPASE RELATED PROTEIN 2
著者Mancheno, J.M, Jayne, S, Kerfelec, B, Chapus, C, Crenon, I, Hermoso, J.A.
登録日2004-08-04
公開日2006-07-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Crystalization of a Proteolyzed Form of the Horse Pancreatic Lipase-Related Protein 2: Structural Basis for the Specific Detergent Requirement.
Acta Crystallogr.,Sect.D, 60, 2004
1N8S
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BU of 1n8s by Molmil
Structure of the pancreatic lipase-colipase complex
分子名称: Triacylglycerol lipase, pancreatic, colipase II
著者van Tilbeurgh, H, Sarda, L, Verger, R, Cambillau, C.
登録日2002-11-21
公開日2002-12-18
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Structure of the pancreatic lipase-procolipase complex
Nature, 359, 1992
2IUK
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BU of 2iuk by Molmil
Crystal structure of Soybean Lipoxygenase-D
分子名称: FE (III) ION, SEED LIPOXYGENASE
著者Youn, B, Sellhorn, G.E, Mirchel, R.J, Gaffney, B.J, Grimes, H.D, Kang, C.
登録日2006-06-05
公開日2006-10-11
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Vegetative Soybean Lipoxygenase Vlx-B and Vlx-D, and Comparisons with Seed Isoforms Lox-1 and Lox-3.
Proteins, 65, 2006
1NO3
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BU of 1no3 by Molmil
REFINED STRUCTURE OF SOYBEAN LIPOXYGENASE-3 WITH 4-NITROCATECHOL AT 2.15 ANGSTROM RESOLUTION
分子名称: 4-NITROCATECHOL, FE (III) ION, Lipoxygenase-3
著者Skrzypczak-Jankun, E, Borbulevych, O.Y, Jankun, J.
登録日2003-01-15
公開日2003-06-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Soybean lipoxygenase-3 in complex with 4-nitrocatechol.
Acta Crystallogr.,Sect.D, 60, 2004
3O8Y
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Stable-5-Lipoxygenase
分子名称: Arachidonate 5-lipoxygenase, FE (II) ION
著者Newcomer, M.E, Gilbert, N.C, Bartlett, S.G, Waight, M.T, Neau, D.B, Boeglin, W.E, Brash, A.R.
登録日2010-08-03
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.389 Å)
主引用文献The structure of human 5-lipoxygenase.
Science, 331, 2011
1BU8
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BU of 1bu8 by Molmil
RAT PANCREATIC LIPASE RELATED PROTEIN 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (PANCREATIC LIPASE RELATED PROTEIN 2)
著者Roussel, A, Cambillau, C.
登録日1998-09-14
公開日1998-12-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and activity of rat pancreatic lipase-related protein 2.
J.Biol.Chem., 273, 1998
2IUJ
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BU of 2iuj by Molmil
Crystal Structure of Soybean Lipoxygenase-B
分子名称: FE (III) ION, LIPOXYGENASE L-5
著者Youn, B, Sellhorn, G.E, Mirchel, R.J, Gaffney, B.J, Grimes, H.D, Kang, C.
登録日2006-06-05
公開日2006-10-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Vegetative Soybean Lipoxygenase Vlx-B and Vlx-D, and Comparisons with Seed Isoforms Lox-1 and Lox-3.
Proteins, 65, 2006
1YGE
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BU of 1yge by Molmil
LIPOXYGENASE-1 (SOYBEAN) AT 100K
分子名称: FE (III) ION, LIPOXYGENASE-1
著者Minor, W, Steczko, J, Stec, B, Otwinowski, Z, Bolin, J.T, Walter, R, Axelrod, B.
登録日1996-06-04
公開日1997-07-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution.
Biochemistry, 35, 1996
1CA1
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BU of 1ca1 by Molmil
ALPHA-TOXIN FROM CLOSTRIDIUM PERFRINGENS
分子名称: ALPHA-TOXIN, CADMIUM ION, ZINC ION
著者Naylor, C.E, Basak, A.K, Titball, R.W.
登録日1998-04-22
公開日1999-05-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the key toxin in gas gangrene.
Nat.Struct.Biol., 5, 1998

 

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