PDB: 7386 resultsInfo pagesStatus searchChemie searchBIRD

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4FXA	Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina with N-acetyl arginine at 1.7 Angstrom resolution Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, N-ALPHA-L-ACETYL-ARGININE, ... Authors: Singh, A, Pandey, S, Kushwaha, G.S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2012-07-03 Release date: 2012-07-25 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina with N-acetyl arginine at 1.7 Angstrom resolution To be Published
2UU9	Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUG-codon in the A-site and paromomycin. Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... Authors: Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V. Deposit date: 2007-03-01 Release date: 2007-05-15 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines. Nat. Struct. Mol. Biol., 14, 2007
4WWW	Crystal structure of the E. coli ribosome bound to CEM-101 Descriptor: (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S rRNA, 23S rRNA, ... Authors: Dunkle, J.A, Zhang, W, Cate, J.H.D, Mankin, A.S. Deposit date: 2014-11-12 Release date: 2014-12-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis. Antimicrob. Agents Chemother., 54, 2010
4WOI	4,5-linked aminoglycoside antibiotics regulate the bacterial ribosome by targeting dynamic conformational processes within intersubunit bridge B2 Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Pulk, A, Cate, J.H.D, Blanchard, S, Wasserman, M, Altman, R, Zhou, Z, Zinder, J, Green, K, Garneau-Tsodikova, S. Deposit date: 2014-10-15 Release date: 2015-08-05 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3 Å) Cite: Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions. Nat Commun, 6, 2015
5TGM	Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... Authors: Melnikov, S, Mailliot, J, Yusupov, M. Deposit date: 2016-09-28 Release date: 2017-01-18 Last modified: 2022-12-07 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
4OTP	Crystal structure of the catalytic domain of the human RioK1 atypical protein kinase in complex with ADP/Mg2+ Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase RIO1 Authors: LaRonde, N.A, Kiburu, I.N. Deposit date: 2014-02-14 Release date: 2014-07-02 Last modified: 2014-08-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes. Nucleic Acids Res., 42, 2014
7SYJ	Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 4(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYL	Structure of the HCV IRES bound to the 40S ribosomal subunit, closed conformation. Structure 6(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYK	Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYI	Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 3(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYO	Structure of the HCV IRES bound to the 40S ribosomal subunit, head open. Structure 9(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S2, HCV IRES, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-27 Last modified: 2022-08-24 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
5TGA	Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... Authors: Melnikov, S, Mailliot, J. Deposit date: 2016-09-27 Release date: 2016-11-23 Last modified: 2016-12-14 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
6T83	Structure of yeast disome (di-ribosome) stalled on poly(A) tract. Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... Authors: Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. Deposit date: 2019-10-24 Release date: 2019-12-25 Last modified: 2020-02-12 Method: ELECTRON MICROSCOPY (4 Å) Cite: Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
4V5R	The crystal structure of EF-Tu and Trp-tRNA-Trp bound to a cognate codon on the 70S ribosome. Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... Authors: Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. Deposit date: 2010-12-07 Release date: 2014-07-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.1 Å) Cite: How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding. Nat.Struct.Mol.Biol., 18, 2011
4V5S	The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a cognate codon on the 70S ribosome. Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... Authors: Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. Deposit date: 2010-12-07 Release date: 2014-07-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.1 Å) Cite: How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding. Nat.Struct.Mol.Biol., 18, 2011
3FRX	Crystal Structure of the Yeast Orthologue of RACK1, Asc1. Descriptor: Guanine nucleotide-binding protein subunit beta-like protein, MANGANESE (II) ION Authors: Coyle, S.M, Gilbert, W.V, Doudna, J.A. Deposit date: 2009-01-08 Release date: 2009-02-17 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Direct link between RACK1 function and localization at the ribosome in vivo Mol.Cell.Biol., 29, 2009
9C4G	Cutibacterium acnes 50S ribosomal subunit with Clindamycin bound Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... Authors: Lomakin, I.B, Devarkar, S.C, Bunick, C.G. Deposit date: 2024-06-04 Release date: 2024-08-21 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: Mechanistic basis for the translation inhibition of Cutibacterium acnes by Clindamycin. J Invest Dermatol., 2024
4V5Q	The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a near- cognate codon on the 70S ribosome Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... Authors: Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. Deposit date: 2010-12-07 Release date: 2014-07-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.1 Å) Cite: How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding. Nat.Struct.Mol.Biol., 18, 2011
6T7I	Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination. Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. Deposit date: 2019-10-22 Release date: 2019-12-25 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
6T7T	Structure of yeast 80S ribosome stalled on poly(A) tract. Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... Authors: Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. Deposit date: 2019-10-23 Release date: 2019-12-25 Last modified: 2020-02-19 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
6T4Q	Structure of yeast 80S ribosome stalled on the CGA-CCG inhibitory codon combination. Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... Authors: Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. Deposit date: 2019-10-14 Release date: 2019-12-25 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
6W6L	Cryo-EM structure of the human ribosome-TMCO1 translocon Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... Authors: Keenan, R.J, McGilvray, P.T. Deposit date: 2020-03-17 Release date: 2020-09-02 Method: ELECTRON MICROSCOPY (3.84 Å) Cite: An ER translocon for multi-pass membrane protein biogenesis. Elife, 9, 2020
6FTJ	Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Non-programmed 80S Ribosome Descriptor: 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... Authors: Braunger, K, Becker, T, Beckmann, R. Deposit date: 2018-02-22 Release date: 2018-03-21 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum. Science, 360, 2018
6FTG	Subtomogram average of OST-containing ribosome-translocon complexes from canine rough microsomal membranes Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... Authors: Pfeffer, S, Foerster, F. Deposit date: 2018-02-22 Release date: 2018-03-21 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (9.1 Å) Cite: Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum. Science, 360, 2018
4Z8C	Crystal structure of the Thermus thermophilus 70S ribosome bound to translation inhibitor oncocin Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Roy, R.N, Lomakin, I.B, Gagnon, M.G, Steitz, T.A. Deposit date: 2015-04-08 Release date: 2015-05-20 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin. Nat.Struct.Mol.Biol., 22, 2015

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