PDB: 98041 resultsInfo pagesStatus searchChemie searchBIRD

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7BPH	Crystal structure of GppNHp-bound GNAS in complex with the cyclic peptide inhibitor GN13 Descriptor: CHLORIDE ION, GLYCEROL, GN13, ... Authors: Hu, Q, Dai, S, Shokat, K.M. Deposit date: 2020-03-22 Release date: 2021-03-31 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.57 Å) Cite: State-selective modulation of heterotrimeric G alpha s signaling with macrocyclic peptides. Cell, 2022
4ECU	Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 200 sec Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.949 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
4ED6	Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 6.7 for 15 hr, Sideway translocation Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-27 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.211 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
7THJ	Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. Deposit date: 2022-01-11 Release date: 2022-02-16 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
1JHB	HUMAN GLUTAREDOXIN IN FULLY REDUCED FORM, NMR, 20 STRUCTURES Descriptor: GLUTAREDOXIN Authors: Sun, C, Bushweller, J.H. Deposit date: 1998-02-17 Release date: 1998-08-26 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: The NMR solution structure of human glutaredoxin in the fully reduced form. J.Mol.Biol., 280, 1998
7EV3	Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-10 and ATP Descriptor: (5S)-5-[(1R)-1-(4-fluoranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Xu, M, Chen, S. Deposit date: 2021-05-20 Release date: 2022-02-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents. Acs Chem.Biol., 17, 2022
6VXW	NMR solution structure of natural scorpion toxin Cl13 Descriptor: Beta-toxin Cl13 Authors: del Rio Portilla, F, Delepierre, M, Lopez Giraldo, A.E. Deposit date: 2020-02-24 Release date: 2020-07-08 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: The three-dimensional structure of the toxic peptide Cl13 from the scorpion Centruroides limpidus. Toxicon, 184, 2020
7EV2	Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-11 and ATP Descriptor: (5S)-5-[(1R)-1-(4-chloranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Xu, M, Chen, S. Deposit date: 2021-05-20 Release date: 2022-02-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents. Acs Chem.Biol., 17, 2022
1U0N	The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex Descriptor: Botrocetin, Platelet glycoprotein Ib, Von Willebrand factor Authors: Fukuda, K, Liddington, R.C. Deposit date: 2004-07-13 Release date: 2005-04-19 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2.95 Å) Cite: The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation Nat.Struct.Mol.Biol., 12, 2005
7BUZ	Crystal structure of Pennisetum glaucum monodehydroascorbate reductase Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pennisetum glaucum monodehydroascorbate reductase Authors: Sonkar, K.S, Arulandu, A, Achary, M.M, Reddy, M.K. Deposit date: 2020-04-08 Release date: 2021-04-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.288 Å) Cite: Crystal structure of Pennisetum glaucum monodehydroascorbate reductase To Be Published
7TZJ	SARS CoV-2 PLpro in complex with inhibitor 3k Descriptor: DIMETHYL SULFOXIDE, N-[(3-fluorophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Papain-like protease, ... Authors: Calleja, D.J, Klemm, T, Lechtenberg, B.C, Kuchel, N.W, Lessene, G, Komander, D. Deposit date: 2022-02-15 Release date: 2022-03-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.66 Å) Cite: Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors. Front Chem, 10, 2022
8D82	Cryo-EM structure of human IL-6 signaling complex in detergent: model containing full extracellular domains Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ... Authors: Zhou, Y, Franklin, M.C. Deposit date: 2022-06-07 Release date: 2023-03-29 Method: ELECTRON MICROSCOPY (3.22 Å) Cite: Structural insights into the assembly of gp130 family cytokine signaling complexes. Sci Adv, 9, 2023
1PJK	Crystal Structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit Descriptor: CHLORIDE ION, Casein kinase II, alpha chain, ... Authors: Ermakova, I, Boldyreff, B, Issinger, O.-G, Niefind, K. Deposit date: 2003-06-03 Release date: 2003-06-24 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit J.Mol.Biol., 330, 2003
1U0X	Crystal structure of nitrophorin 4 under pressure of xenon (200 psi) Descriptor: AMMONIA, Nitrophorin 4, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Nienhaus, K, Maes, E.M, Weichsel, A, Montfort, W.R, Nienhaus, G.U. Deposit date: 2004-07-14 Release date: 2004-07-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Structural dynamics controls nitric oxide affinity in nitrophorin 4 J.Biol.Chem., 279, 2004
4ED3	Human DNA polymerase eta - DNA ternary complex: AT crystal at pH 7.5 (Na+ HEPES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.791 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
5TXY	Identification of a New Zinc Binding Chemotype of by Fragment Screening on human carbonic anhydrase Descriptor: (5R)-5-phenyl-1,3-oxazolidine-2,4-dione, Carbonic anhydrase 2, FORMIC ACID, ... Authors: Ren, B, Peat, T.S, Poulsen, S.-A. Deposit date: 2016-11-17 Release date: 2017-08-30 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.206 Å) Cite: Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
6WHI	Cryo-electron microscopy structure of the type I-F CRISPR RNA-guided surveillance complex bound to the anti-CRISPR AcrIF9 Descriptor: CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy3, ... Authors: Hirschi, M, Santiago-Frangos, A, Wilkinson, R, Golden, S.M, Wiedenheft, B, Lander, G. Deposit date: 2020-04-08 Release date: 2020-05-13 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex. Nat Commun, 11, 2020
5TYA	Identification of a New Zinc Binding Chemotype by Fragment Screening Descriptor: (5R)-5-phenyl-1,3-thiazolidine-2,4-dione, Carbonic anhydrase 2, ZINC ION Authors: Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. Deposit date: 2016-11-18 Release date: 2017-08-30 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
7TPR	Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants Descriptor: Nanobody 7A3, Nanobody 8A2, Spike glycoprotein Authors: Butay, K.J, Zhu, J, Dandey, V.P, Hong, J, Kwon, H.J, Chen, C.Z, Duan, Z, Li, D, Ren, H, Liang, T, Martin, N, Esposito, D, Ortega-Rodriguez, U, Xu, M, Xie, H, Ho, M, Cachau, R, Borgnia, M.J. Deposit date: 2022-01-25 Release date: 2022-04-20 Method: ELECTRON MICROSCOPY (2.39 Å) Cite: Camel nanobodies broadly neutralize SARS-CoV-2 variants bioRxiv, 2021
4ED2	Human DNA polymerase eta - DNA ternary complex: AT crystal at pH 7.2 (Na+ HEPES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Nakamura, T, Zhao, Y, Yang, W. Deposit date: 2012-03-26 Release date: 2012-07-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.711 Å) Cite: Watching DNA polymerase eta make a phosphodiester bond Nature, 487, 2012
7L1Y	Unlocking the structural features for the exo-xylobiosidase activity of an unusual GH11 member identified in a compost-derived consortium-xylobiose complex Descriptor: 1,2-ETHANEDIOL, Exo-B-1,4-beta-xylanase, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose Authors: Kadowaki, M.A.S, Polikarpov, I, Briganti, L, Evangelista, D.E. Deposit date: 2020-12-15 Release date: 2021-07-28 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Unlocking the structural features for the xylobiohydrolase activity of an unusual GH11 member identified in a compost-derived consortium. Biotechnol.Bioeng., 118, 2021
7L1W	Unlocking the structural features for the exo-xylobiosidase activity of an unusual GH11 member identified in a compost-derived consortium Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Exo-B-1,4-beta-xylanase Authors: Kadowaki, M.A.S, Polikarpov, I, Briganti, L, Evangelista, D.E. Deposit date: 2020-12-15 Release date: 2021-07-28 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Unlocking the structural features for the xylobiohydrolase activity of an unusual GH11 member identified in a compost-derived consortium. Biotechnol.Bioeng., 118, 2021
7U72	Human DNA polymerase eta-DNA ternary mismatch complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.53 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U76	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 300s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*())-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.69 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
8D33	Human mitochondrial DNA polymerase gamma ternary complex with GC basepair Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (25-MER), ... Authors: Park, J, Yin, Y.W. Deposit date: 2022-05-31 Release date: 2023-05-24 Last modified: 2023-07-05 Method: ELECTRON MICROSCOPY (2.46 Å) Cite: Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity. Nat.Struct.Mol.Biol., 30, 2023

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