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6MZF
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BU of 6mzf by Molmil
Structural Basis of Tubulin Recruitment and Assembly by Microtubule Polymerases with Tumor Overexpressed Gene (TOG) Domain Arrays
Descriptor: Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Nithianantham, S, Al-Bassam, J.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structural basis of tubulin recruitment and assembly by microtubule polymerases with Tumor Overexpressed Gene (TOG) domain arrays.
Elife, 7, 2018
5WJF
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BU of 5wjf by Molmil
Crystal structure of murine 4-1BB from HEK293T cells in P21212 space group
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor receptor superfamily member 9
Authors:Zajonc, D.M, Doukov, T, Bitra, A.
Deposit date:2017-07-21
Release date:2017-12-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
J. Biol. Chem., 293, 2018
5WA0
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BU of 5wa0 by Molmil
Crystal Structure of the sulfite dehydrogenase, SorT R78Q mutant from Sinorhizobium meliloti
Descriptor: (MOLYBDOPTERIN-S,S)-OXO-MOLYBDENUM, Putative sulfite oxidase
Authors:Maher, M.J.
Deposit date:2017-06-24
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The central active site arginine in sulfite oxidizing enzymes alters kinetic properties by controlling electron transfer and redox interactions.
Biochim. Biophys. Acta, 1859, 2017
6N1C
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BU of 6n1c by Molmil
Crystal structure of Inorganic pyrophosphatase from Legionella pneumophila Philadelphia 1
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ALANINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-11-08
Release date:2018-12-19
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characterization of a family I inorganic pyrophosphatase from Legionella pneumophila Philadelphia 1.
Acta Crystallogr.,Sect.F, 79, 2023
5WM7
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BU of 5wm7 by Molmil
Crystal Structure of CahJ in Complex with AMP
Descriptor: ACETATE ION, ADENOSINE MONOPHOSPHATE, GLYCEROL, ...
Authors:Sikkema, A.P, Smith, J.L.
Deposit date:2017-07-28
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.777 Å)
Cite:A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ.
Chembiochem, 19, 2018
5WAY
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BU of 5way by Molmil
MgaSpn protein, Mga regulator from Streptococcus pneumoniae
Descriptor: GLYCEROL, NICKEL (II) ION, POTASSIUM ION, ...
Authors:Osipiuk, J.
Deposit date:2017-06-27
Release date:2017-07-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:MgaSpn protein, Mga regulator from Streptococcus pneumoniae
To Be Published
5WBJ
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BU of 5wbj by Molmil
Crystal structure of the arabidopsis thaliana Raptor in complex with the TOS peptide of human 4EBP1
Descriptor: Eukaryotic translation initiation factor 4E-binding protein 1, Regulatory-associated protein of TOR 1
Authors:Pavletich, N.P, Jiang, X.
Deposit date:2017-06-29
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
5WBY
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BU of 5wby by Molmil
Crystal structure of mTOR(deltaN)-mLST8-PRAS40(beta-strand) complex
Descriptor: Proline-rich AKT1 substrate 1, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8
Authors:Pavletich, N.P, Yang, H.
Deposit date:2017-06-29
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
6N3Y
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BU of 6n3y by Molmil
Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound 5'-O-[(3-Indolyl)-1-Ethyl]Carbamoyl Guanosine
Descriptor: 5'-O-{[2-(1H-indol-3-yl)ethyl]carbamoyl}guanosine, CHLORIDE ION, Histidine triad nucleotide-binding protein 1
Authors:Strom, A.M, Finzel, B.C.
Deposit date:2018-11-16
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice.
Acs Chem Neurosci, 10, 2019
6N43
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BU of 6n43 by Molmil
Crystal structure of cysteine, nitric oxide-bound ferrous form of the crosslinked human cysteine dioxygenase in the anaerobic condition
Descriptor: CYSTEINE, Cysteine dioxygenase type 1, FE (III) ION, ...
Authors:Liu, A, Li, J.
Deposit date:2018-11-16
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.289 Å)
Cite:Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine.
Biochemistry, 58, 2019
8AJY
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BU of 8ajy by Molmil
Ruminococcus flavefaciens Cohesin-Dockerin structure: dockerin from ScaH adaptor scaffoldin in complex with the cohesin from ScaE anchoring scaffoldin
Descriptor: CALCIUM ION, Cell-wall anchoring protein, Dockerin from ScaH, ...
Authors:Alves, V.D, Bule, P, Fontes, C.M.G.A, Carvalho, A.L.M, Najmudin, S, Duarte, M.
Deposit date:2022-07-28
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structure-function studies can improve binding affinity of cohesin-dockerin interactions for multi-protein assemblies.
Int.J.Biol.Macromol., 224, 2023
5WPS
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BU of 5wps by Molmil
Crystal structure HpiC1 Y101F
Descriptor: 1,2-ETHANEDIOL, 12-epi-hapalindole C/U synthase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Newmister, S.A, Li, S, Garcia-Borras, M, Sanders, J.N, Yang, S, Lowell, A.N, Yu, F, Smith, J.L, Williams, R.M, Houk, K.N, Sherman, D.H.
Deposit date:2017-08-07
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.389 Å)
Cite:Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis.
Nat. Chem. Biol., 14, 2018
5WUM
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BU of 5wum by Molmil
Crystal structure of mouse importin-alpha1 bound to S385-phosphorylated NLS of EBNA1
Descriptor: Epstein-Barr nuclear antigen 1, Importin subunit alpha-1
Authors:Nakada, R, Hirano, H, Matsuura, Y.
Deposit date:2016-12-19
Release date:2017-01-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the regulation of nuclear import of Epstein-Barr virus nuclear antigen 1 (EBNA1) by phosphorylation of the nuclear localization signal.
Biochem. Biophys. Res. Commun., 484, 2017
5WYF
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BU of 5wyf by Molmil
Structure of amino acid racemase, 2.12 A
Descriptor: CADMIUM ION, Isoleucine 2-epimerase, N-[O-PHOSPHONO-PYRIDOXYL]-ISOLEUCINE
Authors:Sakuraba, H, Mutaguchi, Y, Hayashi, J, Ohshima, T.
Deposit date:2017-01-12
Release date:2017-04-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of the novel amino-acid racemase isoleucine 2-epimerase from Lactobacillus buchneri.
Acta Crystallogr D Struct Biol, 73, 2017
3L7E
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BU of 3l7e by Molmil
Crystal structure of ANTI-IL-13 antibody C836
Descriptor: ACETATE ION, C836 HEAVY CHAIN, C836 LIGHT CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2009-12-28
Release date:2010-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Antigen recognition by antibody C836 through adjustment of VL/VH packing
Acta Crystallogr.,Sect.F, 67, 2011
3LS3
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BU of 3ls3 by Molmil
Padron0.9-ON (fluorescent state)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ...
Authors:Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S.
Deposit date:2010-02-12
Release date:2010-03-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron.
J.Biol.Chem., 285, 2010
3L7R
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BU of 3l7r by Molmil
crystal structure of MetE from streptococcus mutans
Descriptor: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, SULFATE ION, ZINC ION
Authors:Fu, T.M, Liang, Y.H, Su, X.D.
Deposit date:2009-12-29
Release date:2011-01-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model
J.Mol.Biol., 412, 2011
5WCT
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BU of 5wct by Molmil
Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 6c (SRI-29775)
Descriptor: 2-{(2S)-1-[(4-chlorophenyl)acetyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein
Authors:Kumar, G, White, S.W.
Deposit date:2017-07-01
Release date:2018-01-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.
Sci Rep, 7, 2017
5WDN
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BU of 5wdn by Molmil
Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 6d (SRI-29680)
Descriptor: 5-hydroxy-6-oxo-2-[(2S)-1-(phenoxyacetyl)pyrrolidin-2-yl]-1,6-dihydropyrimidine-4-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein
Authors:Kumar, G, White, S.W.
Deposit date:2017-07-05
Release date:2018-01-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.
Sci Rep, 7, 2017
3L7F
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BU of 3l7f by Molmil
Structure of IL-13 antibody H2L6, A humanized variant OF C836
Descriptor: CALCIUM ION, H2L6 HEAVY CHAIN, H2L6 LIGHT CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2009-12-28
Release date:2010-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human framework adaptation of a mouse anti-human IL-13 antibody.
J.Mol.Biol., 398, 2010
4PR7
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BU of 4pr7 by Molmil
KdgM porin in complex with disordered oligogalacturonate
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, N-OCTANE, Oligogalacturonate-specific porin KdgM, ...
Authors:Hutter, C, Peneff, C.M, Wirth, C, Schirmer, T.
Deposit date:2014-03-05
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the oligogalacturonate-specific KdgM porin.
Acta Crystallogr.,Sect.D, 70, 2014
6N6F
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BU of 6n6f by Molmil
Vibrio cholerae Oligoribonuclease bound to pGC
Descriptor: Oligoribonuclease, RNA (5'-R(P*GP*C)-3'), SODIUM ION
Authors:Lormand, J.D, Sondermann, H.
Deposit date:2018-11-26
Release date:2019-06-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.735 Å)
Cite:A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation.
Elife, 8, 2019
3LAU
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BU of 3lau by Molmil
Crystal Structure of Aurora2 kinase in complex with a GSK3beta inhibitor
Descriptor: N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]butanamide, Serine/threonine-protein kinase 6
Authors:Maignan, S, Guilloteau, J.P, Pouzieux, S.
Deposit date:2010-01-07
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2.
Bioorg.Med.Chem.Lett., 20, 2010
5X1H
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BU of 5x1h by Molmil
Structure of Legionella pneumophila DotN
Descriptor: IcmJ (DotN), ZINC ION
Authors:Kwak, M.J, Oh, B.H.
Deposit date:2017-01-26
Release date:2017-06-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Architecture of the type IV coupling protein complex of Legionella pneumophila
Nat Microbiol, 2, 2017
5WTU
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BU of 5wtu by Molmil
Crystal structure of DndE G21/24K mutant involved in DNA phosphorothioation
Descriptor: DNA sulfur modification protein DndE
Authors:Yao, P, Liu, Y, Wang, C, Cao, C.
Deposit date:2016-12-14
Release date:2018-02-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of DndE G21/24K mutant involved in DNA phosphorothioation
To Be Published

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