PDB: 94 resultsInfo pagesStatus searchChemie searchBIRD

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8TWI	Cryo-EM structure of the PP2A:B55-FAM122A complex, PP2Ac body Descriptor: FE (III) ION, PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... Authors: Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. Deposit date: 2023-08-21 Release date: 2023-11-01 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.69 Å) Cite: Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
8TWE	Cryo-EM structure of the PP2A:B55-FAM122A complex, B55 body Descriptor: PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... Authors: Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. Deposit date: 2023-08-21 Release date: 2023-11-01 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.55 Å) Cite: Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
8TTB	Cryo-EM structure of the PP2A:B55-ARPP19 complex Descriptor: FE (III) ION, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... Authors: Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. Deposit date: 2023-08-13 Release date: 2023-10-25 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.77 Å) Cite: Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
8U89	The structure of the PP2A-B56Delta holoenzyme mutant - E197K Descriptor: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... Authors: Wu, C.G, Xing, Y. Deposit date: 2023-09-16 Release date: 2024-01-10 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. Proc.Natl.Acad.Sci.USA, 121, 2024
8U1X	The structure of the PP2A-B56Delta holoenzyme mutant - E197K Descriptor: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... Authors: Wu, C.G, Xing, Y. Deposit date: 2023-09-04 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. Proc.Natl.Acad.Sci.USA, 121, 2024
3C5W	Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme Descriptor: PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1 Authors: Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y. Deposit date: 2008-02-01 Release date: 2008-04-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural mechanism of demethylation and inactivation of protein phosphatase 2A. Cell(Cambridge,Mass.), 133, 2008
2NPP	Structure of the Protein Phosphatase 2A Holoenzyme Descriptor: MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ... Authors: Xu, Y, Chen, Y, Xing, Y, Chao, Y, Shi, Y. Deposit date: 2006-10-28 Release date: 2006-12-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure of the protein phosphatase 2A holoenzyme Cell(Cambridge,Mass.), 127, 2006
2NYL	Crystal structure of Protein Phosphatase 2A (PP2A) holoenzyme with the catalytic subunit carboxyl terminus truncated Descriptor: MANGANESE (II) ION, Protein phosphatase 2, regulatory subunit A (PR 65), ... Authors: Xing, Y, Xu, Y, Chen, Y, Chao, Y, Lin, Z, Shi, Y. Deposit date: 2006-11-20 Release date: 2006-12-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structure of the Protein Phosphatase 2A Holoenzyme. Cell(Cambridge,Mass.), 127, 2006
2PF4	Crystal structure of the full-length simian virus 40 small t antigen complexed with the protein phosphatase 2A Aalpha subunit Descriptor: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Small T antigen, ZINC ION Authors: Cho, U, Morrone, S, Xu, W. Deposit date: 2007-04-03 Release date: 2007-08-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis of PP2A inhibition by small t antigen. Plos Biol., 5, 2007
2PKG	Structure of a complex between the A subunit of protein phosphatase 2A and the small t antigen of SV40 Descriptor: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Small T antigen, ZINC ION Authors: Jeffrey, P.D, Shi, Y. Deposit date: 2007-04-17 Release date: 2007-05-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Nat.Struct.Mol.Biol., 14, 2007
2NYM	Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit Descriptor: MANGANESE (II) ION, Protein phosphatase 2, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ... Authors: Chen, Y, Xing, Y, Xu, Y, Chao, Y, Lin, Z, Jeffrey, P.D, Shi, Y. Deposit date: 2006-11-21 Release date: 2006-12-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structure of the Protein Phosphatase 2A Holoenzyme. Cell(Cambridge,Mass.), 127, 2006
8SGH	Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS Descriptor: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, Transportin-1 Authors: Gonzalez, A, Fung, H.Y.J, Chook, Y.M. Deposit date: 2023-04-12 Release date: 2023-06-14 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: A new Karyopherin-beta 2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders. Structure, 31, 2023
8RCH	CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, overall refinement Descriptor: Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Anandapadamanaban, M, Hay, I.M, Perisic, O, Williams, R.L. Deposit date: 2023-12-06 Release date: 2024-09-11 Method: ELECTRON MICROSCOPY (4 Å) Cite: cryoEM structure of mTORC1 with the cancer-associated 1455-EWED-1458 duplication variant, overall refinement To Be Published
8RCK	CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused on one protomer copy. Descriptor: Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Anandapadamanaban, M, Hay, I.M, Perisic, O, Williams, R.L. Deposit date: 2023-12-06 Release date: 2024-09-11 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused on one protomer copy. To Be Published
8RC4	Structure of Integrator-PP2A complex Descriptor: DSS1, Integrator complex subunit 1, Integrator complex subunit 10, ... Authors: Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. Deposit date: 2023-12-06 Release date: 2024-02-07 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
8RBX	Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. Deposit date: 2023-12-05 Release date: 2024-02-07 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
8RBZ	Structure of Integrator-PP2A-SOSS-CTD post-termination complex Descriptor: DNA-directed RNA polymerase subunit, DSS1, Integrator complex subunit 1, ... Authors: Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. Deposit date: 2023-12-05 Release date: 2024-02-07 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
8RCN	CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused region of mTOR and RAPTOR on one protomer copy. Descriptor: Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Anandapadamanaban, M, Hay, I.M, Perisic, O, Williams, R.L. Deposit date: 2023-12-06 Release date: 2024-09-11 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused region of mTOR and RAPTOR on one protomer copy. To Be Published
8SO0	Cryo-EM structure of the PP2A:B55-FAM122A complex Descriptor: FE (III) ION, PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, ... Authors: Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. Deposit date: 2023-04-28 Release date: 2023-10-25 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.79961 Å) Cite: Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024

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