9EM6
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9C81
| X-ray crystal structure of AmpC beta-lactamase with inhibitor | Descriptor: | (2R)-2-phenoxy-3-{[(1S,2S,4S)-spiro[bicyclo[2.2.1]heptane-7,1'-cyclopropane]-2-carbonyl]amino}propanoic acid, AmpC Beta-lactamase | Authors: | Liu, F, Shoichet, B.K, Bassim, V. | Deposit date: | 2024-06-11 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Improved correlations with score, hit-rate, and affinity as docking library and testing scale increase To Be Published
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9GLE
| Jumonji domain-containing protein 2A with crystallization epitope mutations A91T:T93S | Descriptor: | 1,2-ETHANEDIOL, Lysine-specific demethylase 4A, NICKEL (II) ION, ... | Authors: | Fairhead, M, Strain-Damerell, C, Ye, M, Mackinnon, S.R, Pinkas, D, MacLean, E.M, Koekemoer, L, Damerell, D, Krojer, T, Arrowsmith, C.H, Edwards, A, Bountra, C, Yue, W, Burgess-Brown, N, Marsden, B, von Delft, F, Structural Genomics Consortium (SGC) | Deposit date: | 2024-08-27 | Release date: | 2024-09-18 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | A fast, parallel method for efficiently exploring crystallization behaviour of large numbers of protein variants To be published
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9BEI
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9CC8
| Hexameric state of the NRC4 resistosome | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, NLR-required for cell death 4 | Authors: | Liu, F, Yang, Z, Nogales, E, Staskawicz, B.J. | Deposit date: | 2024-06-21 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Activation of the helper NRC4 immune receptor forms a hexameric resistosome. Cell, 187, 2024
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9CC9
| Dodecameric state of the NRC4 resistosome | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, NLR-required for cell death 4 | Authors: | Liu, F, Yang, Z, Nogales, E, Staskawicz, B.J. | Deposit date: | 2024-06-21 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Activation of the helper NRC4 immune receptor forms a hexameric resistosome. Cell, 187, 2024
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9BKE
| STRUCTURE OF 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE (HPAB), OXYGENASE COMPONENT FROM ESCHERICHIA COLI MUTANT XS6 WITH AMP BOUND | Descriptor: | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component, ADENOSINE MONOPHOSPHATE | Authors: | Zhou, D, Chen, L, Rose, J.P, Wang, B.C. | Deposit date: | 2024-04-27 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | STRUCTURE OF 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE (HPAB), OXYGENASE COMPONENT FROM ESCHERICHIA COLI MUTANT XS6 WITH AMP BOUND To Be Published
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9EM7
| Oligomeric structure of SynDLP in presence of GTP | Descriptor: | Slr0869 protein | Authors: | Junglas, B, Gewehr, L, Schoennenbeck, P, Schneider, D, Sachse, C. | Deposit date: | 2024-03-07 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for GTPase activity and conformational changes of the bacterial dynamin-like protein SynDLP. Cell Rep, 43, 2024
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9BJF
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9C83
| X-ray crystal structure of AmpC beta-lactamase with inhibitor | Descriptor: | AmpC Beta-lactamase, N-[(3M)-3-(5-chloro-1,2,3-thiadiazol-4-yl)phenyl]-5-methyl-3-oxo-2,3-dihydro-1,2-oxazole-4-sulfonamide | Authors: | Liu, F, Shoichet, B.K. | Deposit date: | 2024-06-11 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Improved correlations with score, hit-rate, and affinity as docking library and testing scale increase To Be Published
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9FJK
| Omicron BA.1 Spike protein with neutralizing NTD specific mAb K501SP6 | Descriptor: | K501SP6 Fv Heavy Chain, K501SP6 Fv Light Chain, Spike glycoprotein,Fibritin | Authors: | Bjoernsson, K.H, Walker, M.R, Raghavan, S.S.R, Ward, A.B, Barfod, L.K. | Deposit date: | 2024-05-31 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Omicron BA.1 Spike protein with neutralizing NTD specific mAb K501SP6 To Be Published
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9CRW
| Crystal structure of the Candida albicans kinesin-8 proximal tail domain | Descriptor: | Kinesin-like protein | Authors: | Trofimova, D, Doubleday, C, Hunter, B, Serrano Arevalo, J, Davison, E, Wen, E, Munro, K, Allingham, J.S. | Deposit date: | 2024-07-22 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Crystal structure of the Candida albicans kinesin-8 proximal tail domain To Be Published
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9FYP
| Cryo EM structure of the type 3B polymorph of alpha-synuclein at low pH. | Descriptor: | Alpha-synuclein, CHLORIDE ION | Authors: | Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. | Deposit date: | 2024-07-03 | Release date: | 2024-07-17 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.23 Å) | Cite: | On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation. Elife, 12, 2024
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9B0C
| Crystal structure of GenB2 in complex with gentamicin X2. | Descriptor: | (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 6'-epimerase, ... | Authors: | Bury, P.S, Araujo, N.C, Oliveira, G.S, Dias, M.V.B. | Deposit date: | 2024-03-11 | Release date: | 2024-09-11 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis. Acs Chem.Biol., 2024
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9CGI
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8YD3
| Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol | Descriptor: | (2S)-decane-1,2,10-triol, GLYCEROL, Superoxide dismutase [Cu-Zn], ... | Authors: | Aouti, S, Padmanabhan, B. | Deposit date: | 2024-02-19 | Release date: | 2024-08-21 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol To Be Published
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9EUP
| Inhibitor-free outward-open structure of Drosophila dopamine transporter | Descriptor: | 9D5 ANTIBODY, HEAVY CHAIN, LIGHT CHAIN, ... | Authors: | Pedersen, C.N, Yang, F, Ita, S, Xu, Y, Akunuri, R, Trampari, S, Neumann, C.M.T, Desdorf, L.M, Schioett, B, Salvino, J.M, Mortensen, O.V, Nissen, P, Shahsavar, A. | Deposit date: | 2024-03-27 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structure of the dopamine transporter with a novel atypical non-competitive inhibitor bound to the orthosteric site. J.Neurochem., 2024
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7SA5
| Two-state solution NMR structure of Apo Pin1 | Descriptor: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Authors: | Born, A, Vogeli, B. | Deposit date: | 2021-09-22 | Release date: | 2021-10-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Reconstruction of Coupled Intra- and Interdomain Protein Motion from Nuclear and Electron Magnetic Resonance. J.Am.Chem.Soc., 143, 2021
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9EM9
| Structure of SynDLP MGD with GMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Slr0869 protein | Authors: | Junglas, B, Gewehr, L, Schoennenbeck, P, Schneider, D, Sachse, C. | Deposit date: | 2024-03-07 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Structural basis for GTPase activity and conformational changes of the bacterial dynamin-like protein SynDLP. Cell Rep, 43, 2024
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9BK4
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9EM2
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9BEO
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9C8J
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9FWC
| Coxsackievirus B3 3C protease in C121 spacegroup | Descriptor: | Genome polyprotein | Authors: | Fairhead, M, Lithgo, R.M, MacLean, E.M, Bowesman-Jones, H, Aschenbrenner, J.C, Balcomb, B.H, Capkin, E, Chandran, A.V, Godoy, A.S, Marples, P.G, Fearon, D, von Delft, F, Koekemoer, L. | Deposit date: | 2024-06-28 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Coxsackievirus B3 3C protease in C121 spacegroup To Be Published
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8Y6V
| Near-atomic structure of icosahedrally averaged jumbo bacteriophage PhiKZ capsid | Descriptor: | gp119, gp120, gp162, ... | Authors: | Yang, Y, Shao, Q, Guo, M, Han, L, Zhao, X, Wang, A, Li, X, Wang, B, Pan, J, Chen, Z, Fokine, A, Sun, L, Fang, Q. | Deposit date: | 2024-02-03 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Capsid structure of bacteriophage Phi KZ provides insights into assembly and stabilization of jumbo phages. Nat Commun, 15, 2024
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