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2XHM
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BU of 2xhm by Molmil
Crystal structure of AnCE-K26 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ANGIOTENSIN CONVERTING ENZYME, ...
Authors:Akif, M, Ntai, I, Sturrock, E.D, Isaac, R.E, Bachmann, B.O, Acharya, K.R.
Deposit date:2010-06-18
Release date:2010-07-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal Structure of a Phosphonotripeptide K-26 in Complex with Angiotensin Converting Enzyme Homologue (Ance) from Drosophila Melanogaster.
Biochem.Biophys.Res.Commun., 398, 2010
5D6T
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BU of 5d6t by Molmil
Crystal Structure of Aspergillus clavatus Sph3 in complex with GalNAc
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, CHLORIDE ION, SPHERULIN-4, ...
Authors:Bamford, N.C, Little, D.J, Howell, P.L.
Deposit date:2015-08-12
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus.
J.Biol.Chem., 290, 2015
8X83
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BU of 8x83 by Molmil
The cryo-EM structure of insect gustatory receptor Gr43a I418A from Drosophila melanogaster in complex with fructose
Descriptor: Gustatory receptor for sugar taste 43a, SODIUM ION, beta-D-fructofuranose
Authors:Ma, D, Guo, J.
Deposit date:2023-11-27
Release date:2024-02-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for sugar perception by Drosophila gustatory receptors.
Science, 383, 2024
4ZA5
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BU of 4za5 by Molmil
Structure of A. niger Fdc1 with the prenylated-flavin cofactor in the iminium and ketimine forms.
Descriptor: 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, 1-deoxy-5-O-phosphono-1-[(10aR)-2,2,3,4-tetramethyl-8,10-dioxo-1,2,8,9,10,10a-hexahydro-6H-indeno[1,7-ef]pyrimido[4,5-b][1,4]diazepin-6-yl]-D-ribitol, Fdc1, ...
Authors:Payne, K.A.P, Leys, D.
Deposit date:2015-04-13
Release date:2015-06-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:New cofactor supports alpha , beta-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition.
Nature, 522, 2015
6F0B
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BU of 6f0b by Molmil
Cytochrome P450 TxtC employs substrate conformational switching for sequential aliphatic and aromatic thaxtomin hydroxylation
Descriptor: (3~{S},6~{S})-1,4-dimethyl-3-[(4-nitro-1~{H}-indol-3-yl)methyl]-6-(phenylmethyl)piperazine-2,5-dione, Cytochrome P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Fulop, V.
Deposit date:2017-11-17
Release date:2018-12-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC.
J.Am.Chem.Soc., 141, 2019
8X84
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BU of 8x84 by Molmil
The cryo-EM structure of insect gustatory receptor Gr43a I418A from Drosophila melanogaster in complex with fructose and calcium
Descriptor: CALCIUM ION, Gustatory receptor for sugar taste 43a, beta-D-fructofuranose
Authors:Ma, D, Guo, J.
Deposit date:2023-11-27
Release date:2024-02-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for sugar perception by Drosophila gustatory receptors.
Science, 383, 2024
7CYV
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BU of 7cyv by Molmil
Crystal structure of FD20, a neutralizing single-chain variable fragment (scFv) in complex with SARS-CoV-2 Spike receptor-binding domain (RBD)
Descriptor: Spike protein S1, The heavy chain variable region of the scFv FD20,The light chain variable region of the scFv FD20, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Li, Y, Li, T, Lai, Y, Cai, H, Yao, H, Li, D.
Deposit date:2020-09-04
Release date:2021-09-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody.
Embo Mol Med, 13, 2021
8R2H
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BU of 8r2h by Molmil
Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Plasmodium falciparum
Descriptor: 1-deoxy-D-xylulose-5-phosphate synthase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
Authors:Gawriljuk, V.O, Godoy, A.S, Oerlemans, R, Groves, M.R.
Deposit date:2023-11-06
Release date:2024-06-12
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (2.42 Å)
Cite:Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain.
Nat Commun, 15, 2024
5F96
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BU of 5f96 by Molmil
Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235.12 in complex with HIV-1 clade A/E 93TH057 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY CH235.12, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2015-12-09
Release date:2016-03-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2407 Å)
Cite:Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell, 165, 2016
6B3P
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BU of 6b3p by Molmil
Crystal structure of CBMbc (family CBM26) from Eubacterium rectale Amy13K in Complex with Maltoheptaose
Descriptor: 1,2-ETHANEDIOL, Amy13K, FORMIC ACID, ...
Authors:Cockburn, D.W, Wawrzak, Z, Perez Medina, K, Koropatkin, N.M.
Deposit date:2017-09-22
Release date:2017-11-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Novel carbohydrate binding modules in the surface anchored alpha-amylase of Eubacterium rectale provide a molecular rationale for the range of starches used by this organism in the human gut.
Mol. Microbiol., 107, 2018
6SWR
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BU of 6swr by Molmil
Crystal structure of the lysosomal potassium channel MtTMEM175 T38A mutant soaked with zinc
Descriptor: DODECYL-BETA-D-MALTOSIDE, Nanobody, Maltose/maltodextrin-binding periplasmic protein,Maltodextrin-binding protein,Maltose/maltodextrin-binding periplasmic protein, ...
Authors:Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S.
Deposit date:2019-09-23
Release date:2020-04-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for ion selectivity in TMEM175 K + channels.
Elife, 9, 2020
6GLD
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BU of 6gld by Molmil
Intercalation of [Ru(TAP)2(11-Br-dppz)]2+ bound to d(TCGGCGCCGA)2
Descriptor: BARIUM ION, Ruthenium (bis-(tetraazaphenanthrene)) (11-bromo-dipyridophenazine), d(TCGGCGCCGA)2
Authors:McQuaid, K.T, Hall, J.P, Cardin, C.J.
Deposit date:2018-05-23
Release date:2019-06-19
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.061 Å)
Cite:X-ray Crystal Structures Show DNA Stacking Advantage of Terminal Nitrile Substitution in Ru-dppz Complexes.
Chemistry, 24, 2018
5FSG
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BU of 5fsg by Molmil
Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation and a template for drug design
Descriptor: MALTOSE-BINDING PERIPLASMIC PROTEIN, HANTAVIRUS NUCLEOPROTEIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Olal, D, Daumke, O.
Deposit date:2016-01-05
Release date:2016-04-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.209 Å)
Cite:Structure of the Hantavirus Nucleoprotein Provides Insights Into the Mechanism of RNA Encapsidation.
Cell Rep., 14, 2016
4RFN
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BU of 4rfn by Molmil
Crystal structure of ADCC-potent Rhesus macaque ANTIBODY JR4 in complex with HIV-1 CLADE A/E GP120 and M48
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, FAB LIGHT CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, ...
Authors:Gohain, N, Tolbert, W.D, Pazgier, M.
Deposit date:2014-09-26
Release date:2015-07-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1.
J.Virol., 89, 2015
8D6K
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BU of 8d6k by Molmil
Sco GlgEI-V279S in complex with cyclohexyl carbasugar
Descriptor: (1R,4S,5S,6R)-4-(cyclohexylamino)-5,6-dihydroxy-2-(hydroxymethyl)cyclohex-2-en-1-yl alpha-D-glucopyranoside, Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, DI(HYDROXYETHYL)ETHER
Authors:Jayasinghe, T.J, Ronning, D.R.
Deposit date:2022-06-06
Release date:2022-10-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Synthesis of C 7 /C 8 -cyclitols and C 7 N-aminocyclitols from maltose and X-ray crystal structure of Streptomyces coelicolor GlgEI V279S in a complex with an amylostatin GXG-like derivative.
Front Chem, 10, 2022
2X8Y
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BU of 2x8y by Molmil
Crystal structure of AnCE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN CONVERTING ENZYME, CITRATE ANION, ...
Authors:Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R.
Deposit date:2010-03-14
Release date:2010-06-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs.
J.Mol.Biol., 400, 2010
2WR0
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BU of 2wr0 by Molmil
Structures of influenza H2 Hemagglutinins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, ...
Authors:Liu, J, Stevens, D, Haire, L, Coombs, P, Russell, R, Gamblin, S, Skehel, J.
Deposit date:2009-08-28
Release date:2009-09-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
4RHN
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BU of 4rhn by Molmil
HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN (HINT) FROM RABBIT COMPLEXED WITH ADENOSINE
Descriptor: HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN, alpha-D-ribofuranose
Authors:Brenner, C, Garrison, P, Gilmour, J, Peisach, D, Ringe, D, Petsko, G.A, Lowenstein, J.M.
Deposit date:1997-02-26
Release date:1997-06-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins.
Nat.Struct.Biol., 4, 1997
4Y7P
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BU of 4y7p by Molmil
Structure of alkaline D-peptidase from Bacillus cereus
Descriptor: Alkaline D-peptidase, THIOCYANATE ION
Authors:Nakano, S, Okazaki, S, Ishitsubo, E, Kawahara, N, Komeda, H, Tokiwa, H, Asano, Y.
Deposit date:2015-02-15
Release date:2015-10-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and computational analysis of peptide recognition mechanism of class-C type penicillin binding protein, alkaline D-peptidase from Bacillus cereus DF4-B
Sci Rep, 5, 2015
7LS0
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BU of 7ls0 by Molmil
Structure of the Human ALK GRD bound to AUG
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor fused with ALK and LTK ligand 2, CITRIC ACID
Authors:Stayrook, S, Li, T, Klein, D.E.
Deposit date:2021-02-17
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
7LI9
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BU of 7li9 by Molmil
5-HT bound serotonin transporter reconstituted in lipid nanodisc in KCl
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LIA
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BU of 7lia by Molmil
5-HT bound serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in outward facing conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CHOLESTEROL, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LI8
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BU of 7li8 by Molmil
apo serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in inward open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, DODECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
5DFM
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BU of 5dfm by Molmil
Structure of Tetrahymena telomerase p19 fused to MBP
Descriptor: GLYCEROL, Maltose-binding periplasmic protein,Telomerase-associated protein 19, SULFATE ION, ...
Authors:Chan, H, Cascio, D, Sawaya, M.R, Feigon, J.
Deposit date:2015-08-27
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.
Science, 350, 2015
7MPG
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BU of 7mpg by Molmil
Cryo-EM structure of Prefusion-stabilized RSV F (DS-Cav1) in complex with Fab AM14
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AM14 Fab Heavy Chain, AM14 Fab Light Chain, ...
Authors:Abeyrathne, P.D, Malito, E, Harshbarger, W.D.
Deposit date:2021-05-04
Release date:2021-09-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Improved epitope resolution of the prefusion trimer-specific antibody AM14 bound to the RSV F glycoprotein.
Mabs, 13

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