4JTR
 
 | | AKR1C2 complex with ibuprofen | | Descriptor: | (2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid, 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member C2, ... | | Authors: | Yosaatmadja, Y, Flanagan, J.U, Squire, C.J. | | Deposit date: | 2013-03-24 | | Release date: | 2014-04-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structural basis of NSAID selectivity for the AKR1C family
To be Published
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1T47
 | | Structure of fe2-HPPD bound to NTBC | | Descriptor: | 2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHYLENE}CYCLOHEXANE-1,3-DIONE, 4-hydroxyphenylpyruvate dioxygenase, FE (II) ION | | Authors: | Brownlee, J, Johnson-Winters, K, Harrison, D.H.T, Moran, G.R. | | Deposit date: | 2004-04-28 | | Release date: | 2004-06-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the Ferrous Form of (4-Hydroxyphenyl)pyruvate Dioxygenase from Streptomyces avermitilis in Complex with the Therapeutic Herbicide, NTBC
Biochemistry, 43, 2004
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1T4T
 | | arginase-dinor-NOHA complex | | Descriptor: | 3-{[(E)-AMINO(HYDROXYIMINO)METHYL]AMINO}ALANINE, Arginase 1, MANGANESE (II) ION | | Authors: | Cama, E, Pethe, S, Boucher, J.-L, Shoufa, H, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W. | | Deposit date: | 2004-04-30 | | Release date: | 2005-04-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Inhibitor coordination interactions in the binuclear manganese cluster of arginase
Biochemistry, 43, 2004
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7Z1N
 | | Structure of yeast RNA Polymerase III Delta C53-C37-C11 | | Descriptor: | CHAPSO, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Girbig, M, Mueller, C.W. | | Deposit date: | 2022-02-24 | | Release date: | 2022-08-31 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Cell Rep, 40, 2022
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1BXG
 | | PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ AND BETA-PHENYLPROPIONATE | | Descriptor: | HYDROCINNAMIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHENYLALANINE DEHYDROGENASE, ... | | Authors: | Vanhooke, J.L, Thoden, J.B, Brunhuber, N.M.W, Blanchard, J.L, Holden, H.M. | | Deposit date: | 1998-10-02 | | Release date: | 1999-05-18 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Phenylalanine dehydrogenase from Rhodococcus sp. M4: high-resolution X-ray analyses of inhibitory ternary complexes reveal key features in the oxidative deamination mechanism.
Biochemistry, 38, 1999
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7Z1O
 | | Structure of yeast RNA Polymerase III PTC + NTPs | | Descriptor: | CHAPSO, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | | Authors: | Girbig, M, Mueller, C.W. | | Deposit date: | 2022-02-24 | | Release date: | 2022-08-31 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Cell Rep, 40, 2022
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1QCR
 | | CRYSTAL STRUCTURE OF BOVINE MITOCHONDRIAL CYTOCHROME BC1 COMPLEX, ALPHA CARBON ATOMS ONLY | | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, UBIQUINOL CYTOCHROME C OXIDOREDUCTASE | | Authors: | Xia, D, Yu, C.A, Kim, H, Xia, J.Z, Kachurin, A, Zhang, L, Yu, L, Deisenhofer, J. | | Deposit date: | 1997-05-17 | | Release date: | 1998-10-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria.
Science, 277, 1997
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1BLC
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1T8G
 | | Crystal structure of phage T4 lysozyme mutant L32A/L33A/T34A/C54T/C97A/E108V | | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ... | | Authors: | He, M.M, Wood, Z.A, Baase, W.A, Xiao, H, Matthews, B.W. | | Deposit date: | 2004-05-12 | | Release date: | 2004-10-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation.
Protein Sci., 13, 2004
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1CDK
 | | CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT (E.C.2.7.1.37) (PROTEIN KINASE A) COMPLEXED WITH PROTEIN KINASE INHIBITOR PEPTIDE FRAGMENT 5-24 (PKI(5-24) ISOELECTRIC VARIANT CA) AND MN2+ ADENYLYL IMIDODIPHOSPHATE (MNAMP-PNP) AT PH 5.6 AND 7C AND 4C | | Descriptor: | CAMP-DEPENDENT PROTEIN KINASE, MANGANESE (II) ION, MYRISTIC ACID, ... | | Authors: | Bossemeyer, D, Engh, R.A, Kinzel, V, Ponstingl, H, Huber, R. | | Deposit date: | 1994-07-04 | | Release date: | 1995-10-15 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Phosphotransferase and substrate binding mechanism of the cAMP-dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5-24).
EMBO J., 12, 1993
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1H2G
 | | Altered substrate specificity mutant of penicillin acylase | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, PENICILLIN G ACYLASE ALPHA SUBUNIT, ... | | Authors: | McVey, C.E, Morillas, M, Brannigan, J.A, Ladurner, A.G, Forney, L.J, Virden, R. | | Deposit date: | 2002-08-08 | | Release date: | 2003-07-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mutations of Penicillin Acylase Residue B71 Extend Substrate Specificity by Decreasing Steric Constraints for Substrate Binding
Biochem.J., 371, 2003
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3OE0
 | | Crystal structure of the CXCR4 chemokine receptor in complex with a cyclic peptide antagonist CVX15 | | Descriptor: | C-X-C chemokine receptor type 4, Lysozyme Chimera, Polyphemusin analog, ... | | Authors: | Wu, B, Mol, C.D, Han, G.W, Katritch, V, Chien, E.Y.T, Liu, W, Cherezov, V, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR) | | Deposit date: | 2010-08-12 | | Release date: | 2010-10-27 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.
Science, 330, 2010
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3B9X
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4JX1
 | | Crystal structure of reduced Cytochrome P450cam-putidaredoxin complex bound to camphor and 5-exo-hydroxycamphor | | Descriptor: | 1,1'-hexane-1,6-diyldipyrrolidine-2,5-dione, 5-EXO-HYDROXYCAMPHOR, CALCIUM ION, ... | | Authors: | Tripathi, S.M, Li, H, Poulos, T.L. | | Deposit date: | 2013-03-27 | | Release date: | 2013-06-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.087 Å) | | Cite: | Structural basis for effector control and redox partner recognition in cytochrome P450.
Science, 340, 2013
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3B96
 | | Structural Basis for Substrate Fatty-Acyl Chain Specificity: Crystal Structure of Human Very-Long-Chain Acyl-CoA Dehydrogenase | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, TETRADECANOYL-COA, Very long-chain specific acyl-CoA dehydrogenase | | Authors: | McAndrew, R.P, Wang, Y, Mohsen, A.W, He, M, Vockley, J, Kim, J.J. | | Deposit date: | 2007-11-02 | | Release date: | 2008-02-12 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase.
J.Biol.Chem., 283, 2008
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7Z1M
 | | Structure of yeast RNA Polymerase III Elongation Complex (EC) | | Descriptor: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | | Authors: | Girbig, M, Mueller, C.W. | | Deposit date: | 2022-02-24 | | Release date: | 2022-08-31 | | Last modified: | 2022-09-21 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Cell Rep, 40, 2022
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3B9O
 | | long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN | | Descriptor: | Alkane monooxygenase, FLAVIN MONONUCLEOTIDE | | Authors: | Li, L, Yang, W, Xu, F, Bartlam, M, Rao, Z. | | Deposit date: | 2007-11-06 | | Release date: | 2008-01-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase
J.Mol.Biol., 376, 2008
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1QKU
 | | WILD TYPE ESTROGEN NUCLEAR RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH ESTRADIOL | | Descriptor: | ESTRADIOL, ESTRADIOL RECEPTOR | | Authors: | Ruff, M, Gangloff, M, Eiler, S, Duclaud, S, Wurtz, J.M, Moras, D. | | Deposit date: | 1999-08-05 | | Release date: | 2000-08-18 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of a mutant hERalpha ligand-binding domain reveals key structural features for the mechanism of partial agonism.
J. Biol. Chem., 276, 2001
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1H33
 | | Oxidised SoxAX complex from Rhodovulum sulfidophilum | | Descriptor: | CYTOCHROME C, DIHEME CYTOCHROME C, HEME C | | Authors: | Bamford, V.A, Bruno, S, Rasmussen, T, Appia-Ayme, C, Cheesman, M.R, Berks, B.C, Hemmings, A.M. | | Deposit date: | 2002-08-21 | | Release date: | 2002-11-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural Basis for the Oxidation of Thiosulfate by a Sulfur Cycle Enzyme
Embo J., 21, 2002
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3OEC
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1TBH
 | | H141D mutant of rat liver arginase I | | Descriptor: | Arginase 1, MANGANESE (II) ION | | Authors: | Cama, E, Cox, J.D, Ash, D.E, Christianson, D.W. | | Deposit date: | 2004-05-20 | | Release date: | 2005-08-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Probing the role of the hyper-reactive histidine residue of arginase.
Arch.Biochem.Biophys., 444, 2005
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3BG7
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1TDZ
 | | Crystal Structure Complex Between the Lactococcus Lactis FPG (Mutm) and a FAPY-dG Containing DNA | | Descriptor: | 5'-D(*CP*TP*CP*TP*TP*TP*(FOX)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', GLYCEROL, ... | | Authors: | Coste, F, Ober, M, Carell, T, Boiteux, S, Zelwer, C, Castaing, B. | | Deposit date: | 2004-05-24 | | Release date: | 2004-09-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase
J.Biol.Chem., 279, 2004
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6FBB
 | | Crystal structure of 14-3-3 sigma in complex with wild-type Shroom3 | | Descriptor: | 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Leysen, S, Meijer, F.A, Milroy, L.G, Ottmann, C. | | Deposit date: | 2017-12-18 | | Release date: | 2018-03-14 | | Last modified: | 2018-05-09 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Characterization of Coding/Noncoding Variants forSHROOM3in Patients with CKD.
J. Am. Soc. Nephrol., 29, 2018
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1TE7
 | | Solution NMR Structure of Protein yqfB from Escherichia coli. Northeast Structural Genomics Consortium Target ET99 | | Descriptor: | Hypothetical UPF0267 protein yqfB | | Authors: | Atreya, H.S, Shen, Y, Yee, A, Arrowsmith, C, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-05-24 | | Release date: | 2005-01-04 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | G-Matrix Fourier Transform NOESY-Based Protocol for High-Quality Protein Structure Determination
J.Am.Chem.Soc., 127, 2005
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