7YAN
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8K1O
| mycobacterial efflux pump, AMPPNP bound state | Descriptor: | CARDIOLIPIN, MAGNESIUM ION, Multidrug efflux system ATP-binding protein Rv1218c, ... | Authors: | Wang, Y, Wu, F, Zhang, L, Rao, Z. | Deposit date: | 2023-07-11 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | mycobacterial efflux pump, AMPPNP bound state To Be Published
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8K1N
| mycobacterial efflux pump, substrate-bound state | Descriptor: | CARDIOLIPIN, Multidrug efflux system ATP-binding protein Rv1218c, Multidrug efflux system permease protein Rv1217c, ... | Authors: | Wang, Y, Wu, F, Zhang, L, Rao, Z. | Deposit date: | 2023-07-11 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | mycobacterial efflux pump, substrate-bound state To Be Published
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8K1M
| mycobacterial efflux pump, apo state | Descriptor: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CARDIOLIPIN, Multidrug efflux system ATP-binding protein Rv1218c, ... | Authors: | Wang, Y, Wu, F, Zhang, L, Rao, Z. | Deposit date: | 2023-07-11 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | mycobacterial efflux pump, apo state To Be Published
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8K1P
| mycobacterial efflux pump, ADP+vanadate bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, ... | Authors: | Wang, Y, Wu, F, Zhang, L, Rao, Z. | Deposit date: | 2023-07-11 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | mycobacterial efflux pump, ADP+vanadate bound state To Be Published
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7D5Z
| Crystal structure of EBV gH/gL bound with neutralizing antibody 1D8 | Descriptor: | Envelope glycoprotein H, Envelope glycoprotein L, heavy chain of 1D8, ... | Authors: | Zhu, Q, Shan, S, Yu, J, Wang, X, Zhang, L, Zeng, M. | Deposit date: | 2020-09-28 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | A Neutralizing Antibody Targeting a New Site of Vulnerability on Epstein-Barr Virus gH/gL Protects against Dual-Tropic Infection To Be Published
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6IJX
| Crystal Structure of AKR1C1 complexed with meclofenamic acid | Descriptor: | 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid, Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zheng, X, Zhao, Y, Zhang, L, Zhang, H, Chen, Y, Hu, X. | Deposit date: | 2018-10-12 | Release date: | 2019-10-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Screening, synthesis, crystal structure, and molecular basis of 6-amino-4-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles as novel AKR1C3 inhibitors. Bioorg.Med.Chem., 26, 2018
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3S57
| ABH2 cross-linked with undamaged dsDNA-1 containing cofactors | Descriptor: | 2-OXOGLUTARIC ACID, 5'-D(*CP*TP*GP*TP*CP*AP*TP*CP*AP*CP*TP*GP*CP*G)-3', 5'-D(*TP*CP*GP*CP*AP*GP*TP*GP*AP*TP*GP*AP*CP*A)-3', ... | Authors: | Yi, C, Chen, B, Qi, B, Ramirez, B, Zhang, W, Jia, G, Zhang, L, Li, C.Q, Dinner, A.R, Yang, C.-G, He, C. | Deposit date: | 2011-05-20 | Release date: | 2012-06-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Duplex interrogation by a direct DNA repair protein in search of base damage Nat.Struct.Mol.Biol., 19, 2012
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4MC6
| HIV protease in complex with SA499 | Descriptor: | 1,2-ETHANEDIOL, 1-tert-butyl-3-{(2S,3R)-4-[(4R)-7-fluoro-1,1-dioxido-4-(propan-2-yl)-4,5-dihydro-1,2-benzothiazepin-2(3H)-yl]-3-hydroxy-1-phenylbutan-2-yl}urea, CHLORIDE ION, ... | Authors: | Ganguly, A.K, Alluri, S.S, Wang, C, Antropow, A, White, A, Caroccia, D, Biswas, D, Kang, E, Zhang, L, Carroll, S.S, Burlein, C, Munshi, V, Orth, P, Strickland, C. | Deposit date: | 2013-08-21 | Release date: | 2014-04-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Structural Optimization of Cyclic Sulfonamide based Novel HIV-1 Protease Inhibitors to Pico Molar Affinities guided by X-ray Crystallographic Analysis Tetrahedron, 2014
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6J8V
| Structure of MOEN5-SSO7D fusion protein in complex with ligand 2 | Descriptor: | FARNESYL, MoeN5,DNA-binding protein 7d | Authors: | Ko, T.P, Zhang, L.L, Chen, C.C, Guo, R.T. | Deposit date: | 2019-01-21 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism. Biochem. Biophys. Res. Commun., 511, 2019
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4KYK
| Crystal structure of mouse glyoxalase I complexed with indomethacin | Descriptor: | INDOMETHACIN, Lactoylglutathione lyase, ZINC ION | Authors: | Zhai, J, Yuan, M, Zhang, L, Chen, Y, Zhang, H, Chen, S, Zhao, Y. | Deposit date: | 2013-05-29 | Release date: | 2013-08-07 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Zopolrestat as a human glyoxalase I inhibitor and its structural basis. Chemmedchem, 8, 2013
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6J8W
| Structure of MOEN5-SSO7D fusion protein in complex with lig 1 | Descriptor: | (2S)-3-dimethoxyphosphoryloxy-2-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoxy]propanoic acid, MoeN5,DNA-binding protein 7d | Authors: | Ko, T.P, Zhang, L.L, Chen, C.C, Guo, R.T. | Deposit date: | 2019-01-21 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism. Biochem. Biophys. Res. Commun., 511, 2019
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6J5A
| Cryo-EM structure of the mammalian DP-state ATP synthase FO section | Descriptor: | ATP synthase membrane subunit 6.8PL, ATP synthase membrane subunit DAPIT, ATP synthase peripheral stalk-membrane subunit b, ... | Authors: | Gu, J, Zhang, L, Yi, J, Yang, M. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.35 Å) | Cite: | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
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6J5K
| Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit alpha, ... | Authors: | Gu, J, Zhang, L, Yi, J, Yang, M. | Deposit date: | 2019-01-11 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
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7Y9M
| Crystal structure of P450 BM3-2F from Bacillus megaterium | Descriptor: | Bifunctional cytochrome P450/NADPH--P450 reductase, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-06-25 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal structure of P450 BM3-2F from Bacillus megaterium to be published
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7Y9L
| Crystal structure of P450 BM3-2F from Bacillus megaterium in complex with 2-Hydroxy-5-Nitrobenzonitrile | Descriptor: | 5-nitro-2-oxidanyl-benzenecarbonitrile, Bifunctional cytochrome P450/NADPH--P450 reductase, NICKEL (II) ION, ... | Authors: | Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-06-25 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of P450 BM3-2F from Bacillus megaterium in complex with 2-Hydroxy-5-Nitrobenzonitrile to be published
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6M54
| Human apo ferritin frozen on TEM grid with Amorphous nickel titanium alloy supporting film | Descriptor: | FE (II) ION, Ferritin heavy chain | Authors: | Huang, X, Zhang, L, Wen, Z, Chen, H, Li, S, Ji, G, Yin, C, Sun, F. | Deposit date: | 2020-03-09 | Release date: | 2020-05-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation. Prog.Biophys.Mol.Biol., 156, 2020
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3E66
| Crystal structure of the beta-finger domain of yeast Prp8 | Descriptor: | PRP8 | Authors: | Yang, K, Zhang, L, Xu, T, Heroux, A, Zhao, R. | Deposit date: | 2008-08-14 | Release date: | 2008-10-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins. Proc.Natl.Acad.Sci.Usa, 105, 2008
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6M52
| Human apo ferritin frozen on TEM grid with amorphous carbon supporting film | Descriptor: | FE (II) ION, Ferritin heavy chain | Authors: | Huang, X, Zhang, L, Wen, Z, Chen, H, Li, S, Ji, G, Yin, C, Sun, F. | Deposit date: | 2020-03-09 | Release date: | 2020-05-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation. Prog.Biophys.Mol.Biol., 156, 2020
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6J5J
| Cryo-EM structure of the mammalian E-state ATP synthase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit epsilon, ... | Authors: | Gu, J, Zhang, L, Yi, J, Yang, M. | Deposit date: | 2019-01-11 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
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2PVP
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6J5I
| Cryo-EM structure of the mammalian DP-state ATP synthase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit epsilon, ... | Authors: | Gu, J, Zhang, L, Yi, J, Yang, M. | Deposit date: | 2019-01-11 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
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6J54
| Cryo-EM structure of the mammalian E-state ATP synthase FO section | Descriptor: | ATP synthase membrane subunit 6.8PL, ATP synthase membrane subunit DAPIT, ATP synthase peripheral stalk-membrane subunit b, ... | Authors: | Gu, J, Zhang, L, Yi, J, Yang, M. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
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3V36
| Aldose reductase complexed with glceraldehyde | Descriptor: | Aldose reductase, D-Glyceraldehyde, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Zheng, X, Zhang, L, Chen, Y, Luo, H, Hu, X. | Deposit date: | 2011-12-13 | Release date: | 2012-08-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Partial inhibition of aldose reductase by nitazoxanide and its molecular basis. Chemmedchem, 7, 2012
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7KUF
| Transcription activation subcomplex with WhiB7 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA | Descriptor: | DNA (5'-D(*CP*AP*GP*AP*AP*AP*AP*TP*CP*GP*GP*TP*TP*GP*TP*GP*GP*T)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*AP*AP*CP*CP*GP*AP*TP*TP*TP*TP*CP*T)-3'), IRON/SULFUR CLUSTER, ... | Authors: | Wan, T, Horova, M, Beltran, D.G, Li, S.R, Zhang, L.M. | Deposit date: | 2020-11-24 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into the functional divergence of WhiB-like proteins in Mycobacterium tuberculosis. Mol.Cell, 81, 2021
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