7FIR
 
 | | The crystal structure of beta-1,2-mannobiose phosphorylase in complex with 1,4-mannobiose | | 分子名称: | Beta-1,2-mannobiose phosphorylase, PENTAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | | 著者 | Dai, L, Chang, Z, Yang, J, Liu, W, Yang, Y, Chen, C.-C, Zhang, L, Huang, J, Sun, Y, Guo, R.-T. | | 登録日 | 2021-08-01 | | 公開日 | 2022-01-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural investigation of a thermostable 1,2-beta-mannobiose phosphorylase from Thermoanaerobacter sp. X-514.
Biochem.Biophys.Res.Commun., 579, 2021
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7WUQ
 | | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | | 分子名称: | Adhesion G-protein coupled receptor G2,mCherry, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | He, Q.T, Guo, S.C, Xiao, P, Sun, J.P, Yu, X, Gou, L, Kong, L.L, Zhang, L. | | 登録日 | 2022-02-09 | | 公開日 | 2022-04-27 | | 最終更新日 | 2022-05-11 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4.
Nature, 604, 2022
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5B0K
 | | Structure of MoeN5-Sso7d fusion protein in complex with beta-decyl maltoside | | 分子名称: | DECYL-BETA-D-MALTOPYRANOSIDE, MoeN5,DNA-binding protein 7d | | 著者 | Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T. | | 登録日 | 2015-10-30 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
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7CAL
 | | Cryo-EM Structure of the Hyperpolarization-Activated Inwardly Rectifying Potassium Channel KAT1 from Arabidopsis | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Potassium channel KAT1 | | 著者 | Li, S.Y, Yang, F, Sun, D.M, Zhang, Y, Zhang, M.G, Zhou, P, Liu, S.L, Zhang, Y.N, Zhang, L.H, Tian, C.L. | | 登録日 | 2020-06-09 | | 公開日 | 2020-07-29 | | 最終更新日 | 2020-11-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis.
Cell Res., 30, 2020
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6AHF
 | | CryoEM Reconstruction of Hsp104 N728A Hexamer | | 分子名称: | Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Zhang, X, Zhang, L, Zhang, S. | | 登録日 | 2018-08-17 | | 公開日 | 2019-02-13 | | 最終更新日 | 2019-04-10 | | 実験手法 | ELECTRON MICROSCOPY (6.78 Å) | | 主引用文献 | Heat shock protein 104 (HSP104) chaperones soluble Tau via a mechanism distinct from its disaggregase activity.
J. Biol. Chem., 294, 2019
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7QFV
 | | Crystal structure of KLK6 in complex with compound 17a | | 分子名称: | KLK6 Activity-Based Probe (Ahx-DPhe-Ser(Z)-Dht-Arg-DPP), Kallikrein-6 | | 著者 | Jagtap, P.K.A, Zhang, L, De Vita, E, Tate, E.W, Hennig, J. | | 登録日 | 2021-12-06 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion.
J.Am.Chem.Soc., 144, 2022
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8GX9
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7VJN
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7VJO
 | | Pectobacterium phage ZF40 apo-Aca2 | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, anti-CRISPR-associated protein Aca2 | | 著者 | Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D. | | 登録日 | 2021-09-28 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2.
J.Biol.Chem., 297, 2021
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7VJM
 | | Aca1 in complex with 19bp palindromic DNA substrate | | 分子名称: | DNA (5'-D(*AP*TP*TP*AP*GP*GP*CP*AP*CP*AP*TP*TP*GP*TP*GP*CP*CP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*GP*GP*CP*AP*CP*AP*AP*TP*GP*TP*GP*CP*CP*TP*AP*A)-3'), anti-CRISPR-associated protein Aca1 | | 著者 | Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D. | | 登録日 | 2021-09-28 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2.
J.Biol.Chem., 297, 2021
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7VJP
 | | Selenomethionine-derived Pectobacterium phage ZF40 apo-Aca2 | | 分子名称: | SULFATE ION, anti-CRISPR-associated protein Aca2 | | 著者 | Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D. | | 登録日 | 2021-09-28 | | 公開日 | 2021-10-20 | | 最終更新日 | 2022-02-02 | | 実験手法 | X-RAY DIFFRACTION (1.594 Å) | | 主引用文献 | Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2.
J.Biol.Chem., 297, 2021
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3ZWV
 | | Crystal structure of ADP-ribosyl cyclase complexed with ara-2'F-ADP- ribose at 2.3 angstrom | | 分子名称: | ADP-RIBOSYL CYCLASE, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | | 著者 | Kotaka, M, Graeff, R, Zhang, L.H, Lee, H.C, Hao, Q. | | 登録日 | 2011-08-03 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural studies of intermediates along the cyclization pathway of Aplysia ADP-ribosyl cyclase.
J. Mol. Biol., 415, 2012
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3ZWP
 | | Crystal structure of ADP ribosyl cyclase complexed with ara-2'F-ADP- ribose at 2.1 angstrom | | 分子名称: | ADP-RIBOSYL CYCLASE, GLYCEROL, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | | 著者 | Kotaka, M, Graeff, R, Zhang, L.H, Lee, H.C, Hao, Q. | | 登録日 | 2011-08-02 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Structural Studies of Intermediates Along the Cyclization Pathway of Aplysia Adp-Ribosyl Cyclase.
J.Mol.Biol., 415, 2012
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4GPZ
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8H7P
 | | Crystal structure of aqualigase bound with Suc-AAPF | | 分子名称: | 5,6-DIHYDRO-BENZO[H]CINNOLIN-3-YLAMINE, CALCIUM ION, Subtilisin, ... | | 著者 | Li, H, Ma, M.Z, Zhang, L.J, Dai, L, Chen, C.-C, Guo, R.-T. | | 登録日 | 2022-10-20 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal structure of aqualigase bound with Suc-AAPF
To Be Published
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8H7O
 | | Crystal structure of aqualigase | | 分子名称: | CALCIUM ION, ISOPROPYL ALCOHOL, Subtilisin | | 著者 | Li, H, Ma, M.Z, Zhang, L.J, Dai, L, Chen, C.-C, Guo, R.-T. | | 登録日 | 2022-10-20 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of aqualigase
To Be Published
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7RAV
 | | Cryo-EM structure of the unliganded form of NLR family apoptosis inhibitory protein 5 (NAIP5) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Baculoviral IAP repeat-containing protein 1e | | 著者 | Paidimuddala, B, Cao, J, Xie, Q, Wu, H, Zhang, L. | | 登録日 | 2021-07-02 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-03-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Mechanism of NAIP-NLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5.
Nat.Struct.Mol.Biol., 30, 2023
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4X2A
 | | Crystal structure of mouse glyoxalase I complexed with baicalein | | 分子名称: | 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, Lactoylglutathione lyase, ZINC ION | | 著者 | Zhang, H, Zhai, J, Zhang, L, Li, C, Zhao, Y, Hu, X. | | 登録日 | 2014-11-26 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | In Vitro Inhibition of Glyoxalase І by Flavonoids: New Insights from Crystallographic Analysis.
Curr Top Med Chem, 16, 2016
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4GWG
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4WNA
 | | Structure of the Nitrogenase MoFe Protein from Azotobacter vinelandii Pressurized with Xenon | | 分子名称: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | 著者 | Morrison, C.N, Hoy, J.A, Zhang, L, Einsle, O, Rees, D.C. | | 登録日 | 2014-10-11 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Substrate Pathways in the Nitrogenase MoFe Protein by Experimental Identification of Small Molecule Binding Sites.
Biochemistry, 54, 2015
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5DP4
 | | Crystal Structure of EV71 3C Proteinase in complex with compound 3 | | 分子名称: | 3C proteinase, ethyl (2Z,4S)-4-{[(2S)-2-methyl-3-phenylpropanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | | 著者 | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | | 登録日 | 2015-09-12 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochim.Biophys.Acta, 1860, 2016
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4GWK
 | | Crystal structure of 6-phosphogluconate dehydrogenase complexed with 3-phosphoglyceric acid | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-PHOSPHOGLYCERIC ACID, 6-phosphogluconate dehydrogenase, ... | | 著者 | He, C, Zhou, L, Zhang, L. | | 登録日 | 2012-09-03 | | 公開日 | 2012-11-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.534 Å) | | 主引用文献 | Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
Cancer Cell, 22, 2012
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3ZWW
 | | Crystal structure of ADP-ribosyl cyclase complexed with ara-2'F-ADP- ribose at 2.3 angstrom | | 分子名称: | ADP-RIBOSYL CYCLASE, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | | 著者 | Kotaka, M, Graeff, R, Zhang, L.H, Lee, H.C, Hao, Q. | | 登録日 | 2011-08-03 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Studies of Intermediates Along the Cyclization Pathway of Aplysia Adp-Ribosyl Cyclase.
J.Mol.Biol., 415, 2012
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3ZWX
 | | Crystal structure of ADP-ribosyl cyclase complexed with 8-bromo-ADP- ribose | | 分子名称: | ADP-RIBOSYL CYCLASE, CHLORIDE ION, [(2R,3S,4R,5R)-5-(6-amino-8-bromo-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3S,4S)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | | 著者 | Kotaka, M, Graeff, R, Zhang, L.H, Lee, H.C, Hao, Q. | | 登録日 | 2011-08-03 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Studies of Intermediates Along the Cyclization Pathway of Aplysia Adp-Ribosyl Cyclase.
To be Published
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5B0I
 | | Structure of MoeN5-Sso7d fusion protein in complex with beta-octyl glucoside | | 分子名称: | MoeN5,DNA-binding protein 7d, octyl beta-D-glucopyranoside | | 著者 | Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O. | | 登録日 | 2015-10-30 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Angew.Chem.Int.Ed.Engl., 55, 2016
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