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PDB: 34735 件

4UW1
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X-ray crystal structure of human TNKS in complex with a small molecule inhibitor
分子名称: 1,2-ETHANEDIOL, 3-{4-[(dimethylamino)methyl]phenyl}-5-methoxyisoquinolin-1(2H)-one, GLYCEROL, ...
著者Oliver, A.W, Rajasekaran, M.B, Pearl, L.H.
登録日2014-08-08
公開日2015-07-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献Design and Discovery of 3-Aryl-5-Substituted-Isoquinolin-1-Ones as Potent and Selective Tankyrase Inhibitors
Medchemcommm, 6, 2015
4URE
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Molecular Genetic and Crystal Structural Analysis of 1-(4- Hydroxyphenyl)-Ethanol Dehydrogenase from Aromatoleum aromaticum EbN1
分子名称: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ACETATE ION, CYCLOHEXANOL DEHYDROGENASE, ...
著者Buesing, I, Hoeffken, H.W, Breuer, M, Woehlbrand, L, Hauer, B, Rabus, R.
登録日2014-06-28
公開日2015-07-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular Genetic and Crystal Structural Analysis of 1-(4-Hydroxyphenyl)-Ethanol Dehydrogenase from 'Aromatoleum Aromaticum' Ebn1.
J.Mol.Microbiol.Biotechnol., 25, 2015
4V50
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Crystal Structure of Ribosome with messenger RNA and the Anticodon stem-loop of P-site tRNA.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Berk, V, Zhang, W, Pai, R.D, Cate, J.H.D.
登録日2006-08-16
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Structural basis for mRNA and tRNA positioning on the ribosome.
Proc.Natl.Acad.Sci.Usa, 103, 2006
4V1O
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Architecture of the RNA polymerase II-Mediator core transcription initiation complex
分子名称: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
著者Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P.
登録日2014-09-29
公開日2015-02-04
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
4V4L
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Structure of the Drosophila apoptosome
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apaf-1 related killer DARK, MAGNESIUM ION
著者Yuan, S, Topf, M, Akey, C.W, Ludtke, S.J.
登録日2010-10-04
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Structure of the Drosophila apoptosome at 6.9 angstrom resolution
Structure, 19, 2011
4V6E
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Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, W, Dunkle, J.A, Cate, J.H.D.
登録日2009-06-28
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3.712 Å)
主引用文献Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
9BRT
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Intact V-ATPase State 1 and synaptophysin complex in mouse brain isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRZ
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V0-only V-ATPase and synaptophysin complex in mouse brain isolated synaptic vesicles
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-12
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
6CLA
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2.80 A MicroED structure of proteinase K at 6.0 e- / A^2
分子名称: Proteinase K
著者Hattne, J, Shi, D, Glynn, C, Zee, C.-T, Gallagher-Jones, M, Martynowycz, M.W, Rodriguez, J.A, Gonen, T.
登録日2018-03-02
公開日2018-05-16
最終更新日2023-10-04
実験手法ELECTRON CRYSTALLOGRAPHY (2.8 Å)
主引用文献Analysis of Global and Site-Specific Radiation Damage in Cryo-EM.
Structure, 26, 2018
6CLJ
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1.01 A MicroED structure of GSNQNNF at 0.50 e- / A^2
分子名称: ACETATE ION, GSNQNNF, ZINC ION
著者Hattne, J, Shi, D, Glynn, C, Zee, C.-T, Gallagher-Jones, M, Martynowycz, M.W, Rodriguez, J.A, Gonen, T.
登録日2018-03-02
公開日2018-05-16
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (1.01 Å)
主引用文献Analysis of Global and Site-Specific Radiation Damage in Cryo-EM.
Structure, 26, 2018
6CLQ
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1.21 A MicroED structure of GSNQNNF at 2.8 e- / A^2
分子名称: ACETATE ION, GSNQNNF, ZINC ION
著者Hattne, J, Shi, D, Glynn, C, Zee, C.-T, Gallagher-Jones, M, Martynowycz, M.W, Rodriguez, J.A, Gonen, T.
登録日2018-03-02
公開日2018-05-16
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (1.21 Å)
主引用文献Analysis of Global and Site-Specific Radiation Damage in Cryo-EM.
Structure, 26, 2018
9BRS
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BU of 9brs by Molmil
Intact V-ATPase State 2 in synaptophysin knock-out isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRU
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Intact V-ATPase State 1 in synaptophysin knock-out isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
6CMO
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BU of 6cmo by Molmil
Rhodopsin-Gi complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab light chain, ...
著者Kang, Y, Kuybeda, O, de Waal, P.W, Mukherjee, S, Van Eps, N, Dutka, P, Zhou, X.E, Bartesaghi, A, Erramilli, S, Morizumi, T, Gu, X, Yin, Y, Liu, P, Jiang, Y, Meng, X, Zhao, G, Melcher, K, Earnst, O.P, Kossiakoff, A.A, Subramaniam, S, Xu, H.E.
登録日2018-03-05
公開日2018-06-20
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Nature, 558, 2018
6CL9
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2.20 A MicroED structure of proteinase K at 4.3 e- / A^2
分子名称: Proteinase K
著者Hattne, J, Shi, D, Glynn, C, Zee, C.-T, Gallagher-Jones, M, Martynowycz, M.W, Rodriguez, J.A, Gonen, T.
登録日2018-03-02
公開日2018-05-16
最終更新日2023-10-04
実験手法ELECTRON CRYSTALLOGRAPHY (2.2 Å)
主引用文献Analysis of Global and Site-Specific Radiation Damage in Cryo-EM.
Structure, 26, 2018
6CLG
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1.35 A MicroED structure of GSNQNNF at 2.4 e- / A^2
分子名称: ACETATE ION, GSNQNNF, ZINC ION
著者Hattne, J, Shi, D, Glynn, C, Zee, C.-T, Gallagher-Jones, M, Martynowycz, M.W, Rodriguez, J.A, Gonen, T.
登録日2018-03-02
公開日2018-05-16
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (1.35 Å)
主引用文献Analysis of Global and Site-Specific Radiation Damage in Cryo-EM.
Structure, 26, 2018
6CLN
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1.15 A MicroED structure of GSNQNNF at 1.8 e- / A^2
分子名称: ACETATE ION, GSNQNNF, ZINC ION
著者Hattne, J, Shi, D, Glynn, C, Zee, C.-T, Gallagher-Jones, M, Martynowycz, M.W, Rodriguez, J.A, Gonen, T.
登録日2018-03-02
公開日2018-05-16
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (1.15 Å)
主引用文献Analysis of Global and Site-Specific Radiation Damage in Cryo-EM.
Structure, 26, 2018
6CQD
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BU of 6cqd by Molmil
Crystal structure of HPK1 in complex with ATP analogue (AMPPNP)
分子名称: MAGNESIUM ION, Mitogen-activated protein kinase kinase kinase kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Wu, P, Lehoux, I, Franke, Y, Mortara, K, Wang, W.
登録日2018-03-14
公開日2018-12-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer.
Structure, 27, 2019
4W8Q
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Crystal structure of truncated hemolysin A from P. mirabilis at 1.4 Angstroms resolution
分子名称: Hemolysin
著者Novak, W.R.P, Glasgow, E, Thompson, J.R, Weaver, T.M.
登録日2014-08-26
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.428 Å)
主引用文献Proteolysis of truncated hemolysin A yields a stable dimerization interface.
Acta Crystallogr F Struct Biol Commun, 73, 2017
9BRQ
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Intact V-ATPase State 3 and synaptophysin complex in mouse brain isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRY
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BU of 9bry by Molmil
V0-only V-ATPase in synaptophysin gene knock-out mouse brain isolated synaptic vesicles
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-12
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
4WED
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BU of 4wed by Molmil
Crystal structure of ABC transporter substrate-binding protein from Sinorhizobium meliloti
分子名称: ABC transporter, periplasmic solute-binding protein, FORMIC ACID, ...
著者Shabalin, I.G, Otwinowski, Z, Bacal, P, Cymborowski, M.T, Handing, K.B, Stead, M, Hammonds, J, Ahmed, M, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2014-09-09
公開日2014-09-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of ABC transporter substrate-binding protein from Sinorhizobium meliloti
to be published
9BRR
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Intact V-ATPase State 3 in synaptophysin knock-out isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
6CF6
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RNF146 TBM-Tankyrase ARC2-3 complex
分子名称: RNF146, Tankyrase-1
著者Da Rosa, P.A, Xu, W.
登録日2018-02-13
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural basis for tankyrase-RNF146 interaction reveals noncanonical tankyrase-binding motifs.
Protein Sci., 27, 2018
5WCM
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Crystal structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide - new refinement
分子名称: 4-nitrobenzenesulfonamide, Blr6230 protein, ZINC ION
著者Docquier, J.D, Benvenuti, M, Calderone, V, Menciassi, N, Shabalin, I.G, Raczynska, J.E, Wlodawer, A, Jaskolski, M, Minor, W, Mangani, S.
登録日2017-06-30
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides.
Antimicrob. Agents Chemother., 54, 2010

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