4KCV
 
 | | Pyruvate kinase (PYK) from Trypanosoma brucei soaked with 2-oxoglutaric acid | | 分子名称: | 2,6-di-O-phosphono-beta-D-fructofuranose, 2-OXOGLUTARIC ACID, GLYCEROL, ... | | 著者 | Zhong, W, Morgan, H.P, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | | 登録日 | 2013-04-24 | | 公開日 | 2014-01-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Pyruvate kinases have an intrinsic and conserved decarboxylase activity.
Biochem.J., 458, 2014
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4DBH
 | | Crystal structure of Cg1458 with inhibitor | | 分子名称: | 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE, MAGNESIUM ION, OXALATE ION | | 著者 | Ran, T.T, Wang, W.W, Xu, D.Q, Gao, Y.Y. | | 登録日 | 2012-01-15 | | 公開日 | 2012-11-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Crystal structures of Cg1458 reveal a catalytic lid domain and a common catalytic mechanism for FAH family.
Biochem.J., 449, 2013
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6C6K
 | | Structural basis for preferential recognition of cap 0 RNA by a human IFIT1-IFIT3 protein complex | | 分子名称: | Interferon-induced protein with tetratricopeptide repeats 1, Interferon-induced protein with tetratricopeptide repeats 3, MAGNESIUM ION, ... | | 著者 | Amarasinghe, G.K, Leung, D.W, Johnson, B, Xu, W. | | 登録日 | 2018-01-18 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability.
Immunity, 48, 2018
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2FZ1
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6LRS
 | | Cryo-EM structure of RbcL8-RbcS4 from Anabaena sp. PCC 7120 | | 分子名称: | Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain | | 著者 | Xia, L.Y, Jiang, Y.L, Kong, W.W, Sun, H, Li, W.F, Chen, Y, Zhou, C.Z. | | 登録日 | 2020-01-16 | | 公開日 | 2020-07-15 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Molecular basis for the assembly of RuBisCO assisted by the chaperone Raf1.
Nat.Plants, 6, 2020
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3ARQ
 | | Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with IDARUBICIN | | 分子名称: | Chitinase A, GLYCEROL, IDARUBICIN | | 著者 | Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. | | 登録日 | 2010-12-09 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms
J.Biol.Chem., 286, 2011
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3AS3
 | | Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with 2-(imidazolin-2-yl)-5-isothiocyanatobenzofuran | | 分子名称: | 2-(5-isothiocyanato-1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole, Chitinase A, GLYCEROL | | 著者 | Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. | | 登録日 | 2010-12-09 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms
J.Biol.Chem., 286, 2011
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484D
 | | SOLUTION STRUCTURE OF HIV-1 REV PEPTIDE-RNA APTAMER COMPLEX | | 分子名称: | BASIC REV PEPTIDE, RNA APTAMER | | 著者 | Ye, X, Gorin, A.A, Frederick, R, Hu, W, Majumdar, A, Xu, W, Mclendon, G, Ellington, A, Patel, D.J. | | 登録日 | 1999-08-02 | | 公開日 | 1999-10-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | RNA architecture dictates the conformations of a bound peptide.
Chem.Biol., 6, 1999
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1BJZ
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4ZFK
 | | Ergothioneine-biosynthetic Ntn hydrolase EgtC with glutamine | | 分子名称: | 1,2-ETHANEDIOL, Amidohydrolase EgtC, GLUTAMINE | | 著者 | Vit, A, Seebeck, F.P, Blankenfeldt, W. | | 登録日 | 2015-04-21 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC.
Chembiochem, 16, 2015
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1LWH
 | | CRYSTAL STRUCTURE OF T. MARITIMA 4-ALPHA-GLUCANOTRANSFERASE | | 分子名称: | 4-alpha-glucanotransferase, CALCIUM ION | | 著者 | Roujeinikova, A, Raasch, C, Sedelnikova, S, Liebl, W, Rice, D.W. | | 登録日 | 2002-05-31 | | 公開日 | 2002-07-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA 4-ALPHA-GLUCANOTRANSFERASE AND ITS ACARBOSE COMPLEX:
IMPLICATIONS FOR SUBSTRATE SPECIFICITY AND CATALYSIS
J.Mol.Biol., 321, 2002
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3DMX
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3DN3
 | | Iodopentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant | | 分子名称: | 1,2,3,4,5-pentafluoro-6-iodobenzene, 2-HYDROXYETHYL DISULFIDE, Lysozyme, ... | | 著者 | Liu, L, Matthews, B.W. | | 登録日 | 2008-07-01 | | 公開日 | 2008-11-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding.
J.Mol.Biol., 385, 2009
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4AFU
 | | Human Chymase - Fynomer Complex | | 分子名称: | CHYMASE, FYNOMER | | 著者 | Schlatter, D, Brack, S, Banner, D.W, Batey, S, Benz, J, Bertschinger, J, Huber, W, Joseph, C, Rufer, A, Van Der Kloosters, A, Weber, M, Grabulovski, D, Hennig, M. | | 登録日 | 2012-01-23 | | 公開日 | 2012-07-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain.
Mabs, 4, 2012
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6B0G
 | | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245 | | 分子名称: | 1245 Antibody, Heavy Chain, Light Chain, ... | | 著者 | McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P. | | 登録日 | 2017-09-14 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
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6ME3
 | | XFEL crystal structure of human melatonin receptor MT1 in complex with 2-phenylmelatonin | | 分子名称: | DI(HYDROXYETHYL)ETHER, N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide, OLEIC ACID, ... | | 著者 | Stauch, B, Johansson, L.C, McCorvy, J.D, Patel, N, Han, G.W, Gati, C, Batyuk, A, Ishchenko, A, Brehm, W, White, T.A, Michaelian, N, Madsen, C, Zhu, L, Grant, T.D, Grandner, J.M, Olsen, R.H.J, Tribo, A.R, Weierstall, U, Roth, B.L, Katritch, V, Liu, W, Cherezov, V. | | 登録日 | 2018-09-05 | | 公開日 | 2019-04-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis of ligand recognition at the human MT1melatonin receptor.
Nature, 569, 2019
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2QAA
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3DZ5
 | | Human AdoMetDC with covalently bound 5'-[(2-aminooxyethyl)methylamino]-5'-deoxy-8-methyladenosine | | 分子名称: | 1,4-DIAMINOBUTANE, 5'-{[2-(aminooxy)ethyl](methyl)amino}-5'-deoxy-8-methyladenosine, S-adenosylmethionine decarboxylase alpha chain, ... | | 著者 | Bale, S, McCloskey, D.E, Pegg, A.E, Secrist III, J.A, Guida, W.C, Ealick, S.E. | | 登録日 | 2008-07-29 | | 公開日 | 2009-03-10 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | New Insights into the Design of Inhibitors of Human S-Adenosylmethionine Decarboxylase: Studies of Adenine C8 Substitution in Structural Analogues of S-Adenosylmethionine
J.Med.Chem., 52, 2009
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2F0X
 | | Crystal structure and function of human thioesterase superfamily member 2(THEM2) | | 分子名称: | SULFATE ION, Thioesterase superfamily member 2 | | 著者 | Cheng, Z, Song, F, Shan, X, Wang, Y, Wei, Z, Gong, W. | | 登録日 | 2005-11-14 | | 公開日 | 2006-10-10 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of human thioesterase superfamily member 2
Biochem.Biophys.Res.Commun., 349, 2006
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8PEJ
 | | CjGH35 with a Galactosidase Activity-Based Probe | | 分子名称: | (1~{S},2~{S},4~{S},5~{R})-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol, ACETATE ION, Beta-galactosidase, ... | | 著者 | Offen, W.A, Davies, G.J. | | 登録日 | 2023-06-14 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The development of a broad-spectrum retaining beta-exo-galactosidase activity-based probe.
Org.Biomol.Chem., 21, 2023
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6B3J
 | | 3.3 angstrom phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex | | 分子名称: | Exendin-P5, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Liang, Y.L, Khoshouei, M, Glukhova, A, Furness, S.G.B, Koole, C, Zhao, P, Clydesdale, L, Thal, D.M, Radjainia, M, Danev, R, Baumeister, W, Wang, M.W, Miller, L.J, Christopoulos, A, Sexton, P.M, Wootten, D. | | 登録日 | 2017-09-22 | | 公開日 | 2018-02-21 | | 最終更新日 | 2020-01-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex.
Nature, 555, 2018
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4I6P
 | | Crystal structure of Par3-NTD domain | | 分子名称: | Partitioning defective 3 homolog | | 著者 | Wang, W, Gao, F, Gong, W, Sun, F, Feng, W. | | 登録日 | 2012-11-29 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural insights into the intrinsic self-assembly of par-3 N-terminal domain.
Structure, 21, 2013
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1CLA
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4AUO
 | | Crystal structure of MMP-1(E200A) in complex with a triple-helical collagen peptide | | 分子名称: | CALCIUM ION, INTERSTITIAL COLLAGENASE, TRIPLE-HELICAL COLLAGEN PEPTIDE, ... | | 著者 | Manka, S.W, Carafoli, F, Visse, R, Bihan, D, Raynal, N, Farndale, R.W, Murphy, G, Enghild, J.J, Hohenester, E, Nagase, H. | | 登録日 | 2012-05-18 | | 公開日 | 2012-07-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Insights Into Triple-Helical Collagen Cleavage by Matrix Metalloproteinase 1
Proc.Natl.Acad.Sci.USA, 109, 2012
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6ID4
 | | Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01 | | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Lescar, J, Wong, Y.H, Liew, C.W, Gu, Y, MacAry, P.A. | | 登録日 | 2018-09-08 | | 公開日 | 2019-02-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01.
Nat Commun, 10, 2019
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