2P4V
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![BU of 2p4v by Molmil](/molmil-images/mine/2p4v) | Crystal structure of the transcript cleavage factor, GreB at 2.6A resolution | Descriptor: | Transcription elongation factor greB | Authors: | Vassylyeva, M.N, Svetlov, V, Dearborn, A.D, Klyuyev, S, Artsimovitch, I, Vassylyev, D.G. | Deposit date: | 2007-03-13 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The carboxy-terminal coiled-coil of the RNA polymerase beta'-subunit is the main binding site for Gre factors. Embo Rep., 8, 2007
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7QDF
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![BU of 7qdf by Molmil](/molmil-images/mine/7qdf) | Hexameric HIV-1 (M-group) CA R120 mutant | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Gag polyprotein, ... | Authors: | Govasli, M.A.L, Pinotsis, N, McAlpine-Scott, S. | Deposit date: | 2021-11-26 | Release date: | 2022-10-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Evasion of cGAS and TRIM5 defines pandemic HIV. Nat Microbiol, 7, 2022
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4H58
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![BU of 4h58 by Molmil](/molmil-images/mine/4h58) | BRAF in complex with compound 3 | Descriptor: | CHLORIDE ION, N-(4-{[(2-methoxyethyl)amino]methyl}phenyl)-6-(pyridin-4-yl)quinazolin-2-amine, Serine/threonine-protein kinase B-raf | Authors: | Vasbinder, M, Aquila, B, Augustin, M, Chueng, T, Cook, D, Drew, L, Fauber, B, Glossop, S, Godin, R, Grondine, M, Hennessy, E, Johannes, J, Lee, S, Lyne, P, Moertl, M, Omer, C, Palakurthi, S, Pontz, T, Read, J, Sha, L, Shen, M, Steinbacher, S, Wang, H, Wu, A, Ye, M, Bagal, B. | Deposit date: | 2012-09-18 | Release date: | 2013-02-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Discovery and Optimization of a Novel Series of Potent Mutant B-Raf(V600E) Selective Kinase Inhibitors. J.Med.Chem., 56, 2013
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1QSZ
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![BU of 1qsz by Molmil](/molmil-images/mine/1qsz) | THE VEGF-BINDING DOMAIN OF FLT-1 (MINIMIZED MEAN) | Descriptor: | VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 | Authors: | Starovasnik, M.A, Christinger, H.W, Wiesmann, C, Champe, M.A, de Vos, A.M, Skelton, N.J. | Deposit date: | 1999-06-24 | Release date: | 1999-11-10 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states. J.Mol.Biol., 293, 1999
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1QSV
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![BU of 1qsv by Molmil](/molmil-images/mine/1qsv) | THE VEGF-BINDING DOMAIN OF FLT-1, 20 NMR STRUCTURES | Descriptor: | VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 | Authors: | Starovasnik, M.A, Christinger, H.W, Wiesmann, C, Champe, M.A, de Vos, A.M, Skelton, N.J. | Deposit date: | 1999-06-23 | Release date: | 1999-11-10 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states. J.Mol.Biol., 293, 1999
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1EDK
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![BU of 1edk by Molmil](/molmil-images/mine/1edk) | |
1EDI
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1EDJ
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1EDL
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![BU of 1edl by Molmil](/molmil-images/mine/1edl) | |
1ZDB
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1ZDD
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![BU of 1zdd by Molmil](/molmil-images/mine/1zdd) | |
1ZDC
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![BU of 1zdc by Molmil](/molmil-images/mine/1zdc) | |
1ZDA
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4WUO
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![BU of 4wuo by Molmil](/molmil-images/mine/4wuo) | Structure of the E270A Mutant Isopropylmalate dehydrogenase from Thermus thermophilus in complex with IPM, Mn and NADH | Descriptor: | 3-ISOPROPYLMALIC ACID, 3-isopropylmalate dehydrogenase, ETHANOL, ... | Authors: | Pallo, A, Graczer, E, Olah, J, Szimler, T, Konarev, P.V, Svergun, D.I, Merli, A, Zavodszky, P, Vas, M, Weiss, M.S. | Deposit date: | 2014-11-03 | Release date: | 2014-11-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Glutamate 270 plays an essential role in K(+)-activation and domain closure of Thermus thermophilus isopropylmalate dehydrogenase. Febs Lett., 589, 2015
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4F7I
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![BU of 4f7i by Molmil](/molmil-images/mine/4f7i) | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus in complex with IPM, Mn and NADH | Descriptor: | 3-ISOPROPYLMALIC ACID, 3-isopropylmalate dehydrogenase, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | Authors: | Pallo, A, Graczer, E, Zavodszky, P, Weiss, M.S, Vas, M. | Deposit date: | 2012-05-16 | Release date: | 2012-06-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and energetic basis of isopropylmalate dehydrogenase enzyme catalysis. Febs J., 281, 2014
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1VJD
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![BU of 1vjd by Molmil](/molmil-images/mine/1vjd) | Structure of pig muscle PGK complexed with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, phosphoglycerate kinase | Authors: | Flachner, B, Kovari, Z, Varga, A, Gugolya, Z, Vonderviszt, F, Naray-Szabo, G, Vas, M. | Deposit date: | 2004-02-03 | Release date: | 2004-03-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Role of phosphate chain mobility of MgATP in completing the 3-phosphoglycerate kinase catalytic site: binding, kinetic, and crystallographic studies with ATP and MgATP. Biochemistry, 43, 2004
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1VJC
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![BU of 1vjc by Molmil](/molmil-images/mine/1vjc) | Structure of pig muscle PGK complexed with MgATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, phosphoglycerate kinase | Authors: | Flachner, B, Kovari, Z, Varga, A, Gugolya, Z, Vonderviszt, F, Naray-Szabo, G, Vas, M. | Deposit date: | 2004-02-03 | Release date: | 2004-03-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Role of phosphate chain mobility of MgATP in completing the 3-phosphoglycerate kinase catalytic site: binding, kinetic, and crystallographic studies with ATP and MgATP. Biochemistry, 43, 2004
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6UCT
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![BU of 6uct by Molmil](/molmil-images/mine/6uct) | Crystal structure of Mal de Rio Cuarto virus P9-1 viroplasm protein (C-arm deletion mutant) | Descriptor: | p9-1 | Authors: | Llauger, G, Klinke, S, Monti, D, Sycz, G, Cerutti, M.L, Goldbaum, F.A, del Vas, M, Otero, L.H. | Deposit date: | 2019-09-17 | Release date: | 2021-03-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.47 Å) | Cite: | Crystal structure of Mal de Rio Cuarto virus P9-1 viroplasm protein (C-arm deletion mutant) To Be Published
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1KF0
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![BU of 1kf0 by Molmil](/molmil-images/mine/1kf0) | Crystal Structure of Pig Muscle Phosphoglycerate Kinase Ternary Complex with AMP-PCP and 3PG | Descriptor: | 3-PHOSPHOGLYCERIC ACID, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | Authors: | Kovari, Z, Flachner, B, Naray-Szabo, G, Vas, M. | Deposit date: | 2001-11-19 | Release date: | 2002-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystallographic and thiol-reactivity studies on the complex of pig muscle phosphoglycerate kinase with ATP analogues: correlation between nucleotide binding mode and helix flexibility. Biochemistry, 41, 2002
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7KVD
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![BU of 7kvd by Molmil](/molmil-images/mine/7kvd) | Cryo-EM structure of Mal de Rio Cuarto virus P9-1 viroplasm protein (dodecamer) | Descriptor: | p9-1 | Authors: | Llauger, G, Melero, R, Monti, D, Sycz, G, Huck-Iriart, C, Cerutti, M.L, Klinke, S, Arranz, R, Carazo, J.M, Goldbaum, F.A, del Vas, M, Otero, L.H. | Deposit date: | 2020-11-27 | Release date: | 2022-06-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers. Mbio, 14, 2023
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7KVC
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![BU of 7kvc by Molmil](/molmil-images/mine/7kvc) | Cryo-EM structure of Mal de Rio Cuarto virus P9-1 viroplasm protein (decamer) | Descriptor: | p9-1 | Authors: | Llauger, G, Melero, R, Monti, D, Sycz, G, Huck-Iriart, C, Cerutti, M.L, Klinke, S, Arranz, R, Carazo, J.M, Goldbaum, F.A, del Vas, M, Otero, L.H. | Deposit date: | 2020-11-27 | Release date: | 2022-06-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers. Mbio, 14, 2023
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1HDI
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![BU of 1hdi by Molmil](/molmil-images/mine/1hdi) | Pig muscle 3-PHOSPHOGLYCERATE KINASE complexed with 3-PG and MgADP. | Descriptor: | 3-PHOSPHOGLYCERIC ACID, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... | Authors: | Szilagyi, A.N, Ghosh, M, Garman, E, Vas, M. | Deposit date: | 2000-11-16 | Release date: | 2001-02-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A 1.8 A resolution structure of pig muscle 3-phosphoglycerate kinase with bound MgADP and 3-phosphoglycerate in open conformation: new insight into the role of the nucleotide in domain closure. J. Mol. Biol., 306, 2001
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2Y41
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![BU of 2y41 by Molmil](/molmil-images/mine/2y41) | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with IPM and MN | Descriptor: | 3-ISOPROPYLMALATE DEHYDROGENASE, 3-ISOPROPYLMALIC ACID, MANGANESE (II) ION | Authors: | Graczer, E, merlin, A, Singh, R.K, Manikandan, K, Zavodsky, P, Weiss, M.S, Vas, M. | Deposit date: | 2011-01-04 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Atomic Level Description of the Domain Closure in a Dimeric Enzyme: Thermus Thermophilus 3-Isopropylmalate Dehydrogenase. Mol.Biosyst., 7, 2011
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2Y42
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![BU of 2y42 by Molmil](/molmil-images/mine/2y42) | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with NADH and Mn | Descriptor: | 3-ISOPROPYLMALATE DEHYDROGENASE, BICINE, MANGANESE (II) ION, ... | Authors: | Graczer, E, merlin, A, Singh, R.K, Manikandan, K, Zavodsky, P, Weiss, M.S, Vas, M. | Deposit date: | 2011-01-04 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Atomic Level Description of the Domain Closure in a Dimeric Enzyme: Thermus Thermophilus 3-Isopropylmalate Dehydrogenase. Mol.Biosyst., 7, 2011
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2Y3Z
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![BU of 2y3z by Molmil](/molmil-images/mine/2y3z) | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - apo enzyme | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-ISOPROPYLMALATE DEHYDROGENASE, GLYCEROL, ... | Authors: | Graczer, E, merlin, A, Singh, R.K, Manikandan, K, Zavodsky, P, Weiss, M.S, Vas, M. | Deposit date: | 2011-01-04 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Atomic Level Description of the Domain Closure in a Dimeric Enzyme: Thermus Thermophilus 3-Isopropylmalate Dehydrogenase. Mol.Biosyst., 7, 2011
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