6XAK
| Crystal structure of NzeB in complex with cyclo-(L-Trp-L-Pro) and cyclo-(L-Trp-L-Trp) | 分子名称: | (3S,6S)-3,6-bis[(1H-indol-3-yl)methyl]piperazine-2,5-dione, (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, 1,2-ETHANEDIOL, ... | 著者 | Shende, V.V, Khatri, Y, Newmister, S.A, Sanders, J.N, Lindovska, P, Yu, F, Doyon, T.J, Kim, J, Movassaghi, M, Houk, K.N, Sherman, D.H. | 登録日 | 2020-06-04 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.479 Å) | 主引用文献 | Structure and Function of NzeB, a Versatile C-C and C-N Bond-Forming Diketopiperazine Dimerase. J.Am.Chem.Soc., 142, 2020
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5AJP
| Crystal structure of the active form of GalNAc-T2 in complex with UDP and the glycopeptide MUC5AC-13 | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, MANGANESE (II) ION, MUCIN, ... | 著者 | Lira-Navarrete, E, delasRivas, M, Companon, I, Pallares, M.C, Kong, Y, Iglesias-Fernandez, J, Bernardes, G.J.L, Peregrina, J.M, Rovira, C, Bernado, P, Bruscolini, P, Clausen, H, Lostao, A, Corzana, F, Hurtado-Guerrero, R. | 登録日 | 2015-02-26 | 公開日 | 2015-03-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Dynamic Interplay between Catalytic and Lectin Domains of Galnac-Transferases Modulates Protein O-Glycosylation. Nat.Commun., 6, 2015
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5AJN
| Crystal structure of the inactive form of GalNAc-T2 in complex with the glycopeptide MUC5AC-Cys13 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUCIN, ... | 著者 | Lira-Navarrete, E, delasRivas, M, Companon, I, Pallares, M.C, Kong, Y, Iglesias-Fernandez, J, Bernardes, G.J.L, Peregrina, J.M, Rovira, C, Bernado, P, Bruscolini, P, Clausen, H, Lostao, A, Corzana, F, Hurtado-Guerrero, R. | 登録日 | 2015-02-26 | 公開日 | 2015-03-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Dynamic Interplay between Catalytic and Lectin Domains of Galnac-Transferases Modulates Protein O-Glycosylation. Nat.Commun., 6, 2015
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5AJO
| Crystal structure of the inactive form of GalNAc-T2 in complex with the glycopeptide MUC5AC-3,13 | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUCIN, POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2, ... | 著者 | Lira-Navarrete, E, delasRivas, M, Companon, I, Pallares, M.C, Kong, Y, Iglesias-Fernandez, J, Bernardes, G.J.L, Peregrina, J.M, Rovira, C, Bernado, P, Bruscolini, P, Clausen, H, Lostao, A, Corzana, F, Hurtado-Guerrero, R. | 登録日 | 2015-02-26 | 公開日 | 2015-03-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Dynamic Interplay between Catalytic and Lectin Domains of Galnac-Transferases Modulates Protein O-Glycosylation. Nat.Commun., 6, 2015
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1OSG
| Complex between BAFF and a BR3 derived peptide presented in a beta-hairpin scaffold | 分子名称: | BR3 derived PEPTIDE, MAGNESIUM ION, Tumor necrosis factor ligand superfamily member 13B | 著者 | Gordon, N.C, Pan, B, Hymowitz, S.G, Yin, J.P, Kelley, R.F, Cochran, A.G, Yan, M, Dixit, V.M, Fairbrother, W.J, Starovasnik, M.A. | 登録日 | 2003-03-19 | 公開日 | 2003-05-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site Biochemistry, 42, 2003
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4EUU
| Structure of BX-795 Complexed with Human TBK1 Kinase Domain Phosphorylated on Ser172 | 分子名称: | GLYCEROL, IODIDE ION, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, ... | 著者 | Ma, X, Helgason, E, Phung, Q.T, Quan, C.L, Iyer, R.S, Lee, M.W, Bowman, K.K, Starovasnik, M.A, Dueber, E.C. | 登録日 | 2012-04-25 | 公開日 | 2012-05-23 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation. Proc.Natl.Acad.Sci.USA, 109, 2012
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1MPV
| Structure of bhpBR3, the BAFF-binding loop of BR3 embedded in a beta-hairpin peptide | 分子名称: | BLyS Receptor 3 | 著者 | Kayagaki, N, Yan, M, Seshasayee, D, Wang, H, Lee, W, French, D.M, Grewal, I.S, Cochran, A.G, Gordon, N.C, Yin, J, Starovasnik, M.A, Dixit, V.M. | 登録日 | 2002-09-12 | 公開日 | 2002-10-30 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. Immunity, 17, 2002
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6H0B
| Crystal structure of the human GalNAc-T4 in complex with UDP, manganese and the diglycopeptide 6. | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-galactopyranose, ALA-THR-GLY-ALA-GLY-ALA-GLY-ALA-GLY-THR-THR-PRO-GLY-PRO-GLY, ... | 著者 | de las Rivas, M, Daniel, E.J.P, Coelho, H, Lira-Navarrete, E, Raich, L, Companon, I, Diniz, A, Lagartera, L, Jimenez-Barbero, J, Clausen, H, Rovira, C, Marcelo, F, Corzana, F, Gerken, T.A, Hurtado-Guerrero, R. | 登録日 | 2018-07-08 | 公開日 | 2018-10-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4. ACS Cent Sci, 4, 2018
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4K3J
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1XU1
| The crystal structure of APRIL bound to TACI | 分子名称: | NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 13B | 著者 | Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A. | 登録日 | 2004-10-25 | 公開日 | 2004-11-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding J.Biol.Chem., 280, 2005
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4EUT
| Structure of BX-795 Complexed with Unphosphorylated Human TBK1 Kinase-ULD Domain | 分子名称: | IODIDE ION, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, SULFATE ION, ... | 著者 | Ma, X, Helgason, E, Phung, Q.T, Quan, C.L, Iyer, R.S, Lee, M.W, Bowman, K.K, Starovasnik, M.A, Dueber, E.C. | 登録日 | 2012-04-25 | 公開日 | 2012-05-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation. Proc.Natl.Acad.Sci.USA, 109, 2012
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5FV9
| Crystal structure of GalNAc-T2 in complex with compound 16d | 分子名称: | 1,2-ETHANEDIOL, GALNAC-T2, GLYCEROL, ... | 著者 | Ghirardello, M, Rivas, M, Lacetera, A, Delso, I, Lira-Navarrete, E, Tejero, T, Martin-Santamaria, S, Hurtado-Guerrero, R, Merino, P. | 登録日 | 2016-02-03 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Glycomimetics Targeting Glycosyltransferases: Synthetic, Computational and Structural Studies of Less-Polar Conjugates. Chemistry, 22, 2016
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5NDF
| Small-molecule inhibition of ppGalNAc-Ts selectively reduces mucin-type O-glycosylation | 分子名称: | 1,2-ETHANEDIOL, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, MANGANESE (II) ION, ... | 著者 | Hurtado-Guerrero, R, De las Rivas, M. | 登録日 | 2017-03-08 | 公開日 | 2017-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The small molecule luteolin inhibits N-acetyl-alpha-galactosaminyltransferases and reduces mucin-type O-glycosylation of amyloid precursor protein. J. Biol. Chem., 292, 2017
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5WDA
| Structure of the PulG pseudopilus | 分子名称: | CALCIUM ION, General secretion pathway protein G | 著者 | Lopez-Castilla, A, Thomassin, J.L, Bardiaux, B, Zheng, W, Nivaskumar, M, Yu, X, Nilges, M, Egelman, E.H, Izadi-Pruneyre, N, Francetic, O. | 登録日 | 2017-07-04 | 公開日 | 2017-10-25 | 最終更新日 | 2020-01-01 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Structure of the calcium-dependent type 2 secretion pseudopilus. Nat Microbiol, 2, 2017
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1MRB
| THREE-DIMENSIONAL STRUCTURE OF RABBIT LIVER CD7 METALLOTHIONEIN-2A IN AQUEOUS SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE | 分子名称: | CADMIUM ION, CD7 METALLOTHIONEIN-2A | 著者 | Braun, W, Arseniev, A, Schultze, P, Woergoetter, E, Wagner, G, Vasak, M, Kaegi, J.H.R, Wuthrich, K. | 登録日 | 1990-05-14 | 公開日 | 1991-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance. J.Mol.Biol., 201, 1988
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2IPC
| Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals a parallel, head-to-head dimer | 分子名称: | Preprotein translocase SecA subunit | 著者 | Vassylyev, D.G, Mori, H, Vassylyeva, M.N, Tsukazaki, T, Kimura, Y, Tahirov, T.H, Ito, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-10-12 | 公開日 | 2006-11-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of the Translocation ATPase SecA from Thermus thermophilus Reveals a Parallel, Head-to-Head Dimer. J.Mol.Biol., 364, 2006
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6S24
| Crystal structure of the TgGalNAc-T3 in complex with UDP, manganese and the peptide 3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ALA-THR-GLY-ALA-GLY-ALA-GLY-ALA-GLY-THR-THR-PRO-GLY-PRO, ... | 著者 | de las Rivas, M, Daniel, E.J.P, Narimatsu, Y, Companon, I, Kato, K, Hermosilla, P, Thureau, A, Ceballos-Laita, L, Coelho, H, Bernado, P, Marcelo, F, Hansen, L, Lostao, A, Corzana, F, Clausen, H, Gerken, T.A, Hurtado-Guerrero, R. | 登録日 | 2019-06-20 | 公開日 | 2019-12-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3. Nat.Chem.Biol., 16, 2020
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1CED
| THE STRUCTURE OF CYTOCHROME C6 FROM MONORAPHIDIUM BRAUNII, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | CYTOCHROME C6, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Banci, L, Bertini, I, Quacquarini, G, Walter, O, Diaz, A, Hervas, M, De La Rosa, M.A. | 登録日 | 1996-03-06 | 公開日 | 1996-08-17 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of cytochrome c6 from the green alga Monoraphidium braunii J.Biol.Inorg.Chem., 1, 1996
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1VGH
| HEPARIN-BINDING DOMAIN FROM VASCULAR ENDOTHELIAL GROWTH FACTOR, NMR, 20 STRUCTURES | 分子名称: | VASCULAR ENDOTHELIAL GROWTH FACTOR-165 | 著者 | Fairbrother, W.J, Champe, M.A, Christinger, H.W, Keyt, B.A, Starovasnik, M.A. | 登録日 | 1997-12-17 | 公開日 | 1998-04-08 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the heparin-binding domain of vascular endothelial growth factor. Structure, 6, 1998
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6S22
| Crystal structure of the TgGalNAc-T3 in complex with UDP, manganese and FGF23c | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | de las Rivas, M, Daniel, E.J.P, Narimatsu, Y, Companon, I, Kato, K, Hermosilla, P, Thureau, A, Ceballos-Laita, L, Coelho, H, Bernado, P, Marcelo, F, Hansen, L, Lostao, A, Corzana, F, Clausen, H, Gerken, T.A, Hurtado-Guerrero, R. | 登録日 | 2019-06-20 | 公開日 | 2019-12-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3. Nat.Chem.Biol., 16, 2020
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1XU2
| The crystal structure of APRIL bound to BCMA | 分子名称: | NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 17 | 著者 | Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A. | 登録日 | 2004-10-25 | 公開日 | 2004-11-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding J.Biol.Chem., 280, 2005
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1XUT
| Solution structure of TACI-CRD2 | 分子名称: | Tumor necrosis factor receptor superfamily member 13B | 著者 | Hymowitz, S.G, Patel, D.R, Wallweber, H.J, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A. | 登録日 | 2004-10-26 | 公開日 | 2004-11-09 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding. J.Biol.Chem., 280, 2005
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1RJ8
| The crystal structure of TNF family member EDA-A2 | 分子名称: | ectodysplasin-A isoform EDA-A2 | 著者 | Hymowitz, S.G, Compaan, D.M, Yan, M, Ackerly, H, Dixit, V.M, Starovasnik, M.A, de Vos, A.M. | 登録日 | 2003-11-18 | 公開日 | 2003-12-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | The Crystal Structure of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity STRUCTURE, 11, 2003
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1RJ7
| Crystal structure of EDA-A1 | 分子名称: | Ectodysplasin A | 著者 | Hymowitz, S.G, Compaan, D.M, Yan, M, Ackerly, H, Dixit, V.M, Starovasnik, M.A, de Vos, A.M. | 登録日 | 2003-11-18 | 公開日 | 2003-12-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity. Structure, 11, 2003
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4DSO
| Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, BENZAMIDINE, GLYCEROL, ... | 著者 | Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. | 登録日 | 2012-02-19 | 公開日 | 2012-04-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc.Natl.Acad.Sci.USA, 109, 2012
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