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PDB: 36 results

7BPV
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BU of 7bpv by Molmil
r(GUGGGCCGAC)/d(GTCGGCCCAC) hybrid duplex structure
Descriptor: DNA (5'-D(P*GP*TP*CP*GP*GP*CP*CP*CP*AP*C)-3'), RNA (5'-R(P*GP*UP*GP*GP*GP*CP*CP*GP*AP*C)-3'), SULFATE ION
Authors:Wang, S.C, Satange, R.B, Hou, M.H.
Deposit date:2020-03-23
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.781 Å)
Cite:Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction.
Nucleic Acids Res., 49, 2021
5YZE
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BU of 5yze by Molmil
Crystal structure of the [Co2+-(chromomycin A3)2]-d(CCG)3 complex
Descriptor: (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ...
Authors:Hou, M.H, Chen, Y.W, Wu, P.C, Satange, R.B.
Deposit date:2017-12-14
Release date:2018-10-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:CoII(Chromomycin)2 Complex Induces a Conformational Change of CCG Repeats from i-Motif to Base-Extruded DNA Duplex
Int J Mol Sci, 19, 2018
7Y2P
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Crystal structure of CUG repeat RNA duplex containing A-U base pair and U-U mismatches
Descriptor: RNA (5'-R(P*UP*UP*CP*UP*GP*CP*AP*GP*CP*UP*GP*AP*A)-3'), RNA (5'-R(P*UP*UP*CP*UP*GP*CP*UP*GP*CP*UP*GP*AP*A)-3')
Authors:Wang, S.C, Satange, R.B, Hou, M.H.
Deposit date:2022-06-09
Release date:2023-05-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural basis for water modulating RNA duplex formation in the CUG repeats of myotonic dystrophy type 1.
J.Biol.Chem., 299, 2023
6L75
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BU of 6l75 by Molmil
Crystal structure of d(GTGGGCCGAC)2 DNA duplex
Descriptor: DNA (5'-D(P*GP*TP*GP*GP*GP*CP*CP*GP*AP*C)-3')
Authors:Hou, M.H, Satange, R.B, Zeng, J.Y.
Deposit date:2019-10-31
Release date:2021-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.578 Å)
Cite:Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction.
Nucleic Acids Res., 49, 2021
7Y2B
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BU of 7y2b by Molmil
Crystal structure of CUG repeat RNA duplex containing U-U mismatches
Descriptor: RNA (5'-R(P*UP*UP*CP*UP*GP*CP*UP*GP*CP*UP*GP*AP*A)-3')
Authors:Wang, S.C, Satange, R.B, Hou, M.H.
Deposit date:2022-06-09
Release date:2023-05-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural basis for water modulating RNA duplex formation in the CUG repeats of myotonic dystrophy type 1.
J.Biol.Chem., 299, 2023
7X97
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BU of 7x97 by Molmil
Crystal structure of actinomycin D-echinomycin-d(AGCCCGT/ACGGGCT) complex
Descriptor: 2-CARBOXYQUINOXALINE, Actinomycin D, CHLORIDE ION, ...
Authors:Kao, S.H, Satange, R.B, Hou, M.H.
Deposit date:2022-03-15
Release date:2022-12-14
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
7XDJ
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BU of 7xdj by Molmil
Crystal structure of actinomycin D-echinomycin-d(AGCGCGT/ACGAGCT) complex
Descriptor: 2-CARBOXYQUINOXALINE, CHLORIDE ION, DNA (5'-D(P*AP*CP*GP*AP*GP*CP*(BRU))-3'), ...
Authors:Chien, C.M, Satange, R.B, Hou, M.H.
Deposit date:2022-03-27
Release date:2022-12-14
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.435 Å)
Cite:Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
5ZT2
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BU of 5zt2 by Molmil
Crystal structure of CCG DNA repeats at 1.66 angstrom resolution
Descriptor: COBALT (II) ION, DNA (5'-D(*TP*CP*CP*GP*CP*CP*GP*CP*CP*GP*A)-3')
Authors:Hou, M.H, Wu, P.C, Satange, R.B, Chen, Y.W.
Deposit date:2018-05-01
Release date:2019-05-15
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.66002166 Å)
Cite:Crystallographic analysis of conformational change in CCG repeats into i-motif and unusual DNA duplex in presence and absence of CoII(Chro)2 complex
To Be Published
5XJW
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BU of 5xjw by Molmil
Crystal Structure of the [Co2+-(Chromomycin A3)2]-CCG repeats Complex
Descriptor: (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-4-O-acetyl-2,6-dideoxy-beta-D-galactopyranose, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-beta-D-Olivopyranose-(1-3)-beta-D-Olivopyranose, ...
Authors:Tseng, W.H, Wu, P.C, Satange, R.B, Hou, M.H.
Deposit date:2017-05-04
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Crystal Structure of the [Co2+-(Chromomycin A3)2]-CCG repeats Complex
To be published
7X9F
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BU of 7x9f by Molmil
Crystal structure of actinomycin D-echinomycin-d(AGCGCGT/ACGCGCT) complex
Descriptor: 2-CARBOXYQUINOXALINE, DNA (5'-D(P*AP*CP*GP*CP*GP*CP*T)-3'), DNA (5'-D(P*AP*GP*CP*GP*CP*GP*T)-3'), ...
Authors:Kao, S.H, Satange, R.B, Hou, M.H.
Deposit date:2022-03-15
Release date:2022-12-14
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
7X6R
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BU of 7x6r by Molmil
Crystal structure of actinomycin D-echinomycin-d(AGCACGT/ACGGGCT) complex
Descriptor: 2-CARBOXYQUINOXALINE, Actinomycin D, COBALT (II) ION, ...
Authors:Kao, S.H, Satange, R.B, Hou, M.H.
Deposit date:2022-03-08
Release date:2022-12-14
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism.
Nucleic Acids Res., 50, 2022
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