4V5N
| tRNA translocation on the 70S ribosome: the post- translocational translocation intermediate TI(POST) | Descriptor: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Ratje, A.H, Loerke, J, Mikolajka, A, Bruenner, M, Hildebrand, P.W, Starosta, A.L, Doenhoefer, A, Connell, S.R, Fucini, P, Mielke, T, Whitford, P.C, Onuchic, J.N, Yu, Y, Sanbonmatsu, K.Y, Hartmann, R.K, Penczek, P.A, Wilson, D.N, Spahn, C.M.T. | Deposit date: | 2010-10-21 | Release date: | 2014-07-09 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites. Nature, 468, 2010
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5AJ0
| Cryo electron microscopy of actively translating human polysomes (POST state). | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T. | Deposit date: | 2015-02-19 | Release date: | 2015-05-20 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural Snapshots of Actively Translating Human Ribosomes Cell(Cambridge,Mass.), 161, 2015
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6YGC
| Crystal structure of the NatC complex bound to Arl3 peptide and CoA | Descriptor: | ADP-ribosylation factor-like protein 3, CHLORIDE ION, COENZYME A, ... | Authors: | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | Deposit date: | 2020-03-27 | Release date: | 2020-10-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.994 Å) | Cite: | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
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3DEG
| Complex of elongating Escherichia coli 70S ribosome and EF4(LepA)-GMPPNP | Descriptor: | 30S RNA helix 14, 30S RNA helix 8, 30S ribosomal protein S12, ... | Authors: | Connell, S.R, Topf, M, Qin, Y, Wilson, D.N, Mielke, T, Fucini, P, Nierhaus, K.H, Spahn, C.M.T. | Deposit date: | 2008-06-10 | Release date: | 2008-08-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (10.9 Å) | Cite: | A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation Nat.Struct.Mol.Biol., 15, 2008
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3CF5
| Thiopeptide antibiotic Thiostrepton bound to the large ribosomal subunit of Deinococcus radiodurans | Descriptor: | 50S RIBOSOMAL PROTEIN L11, 50S RIBOSOMAL PROTEIN L13, 50S RIBOSOMAL PROTEIN L14, ... | Authors: | Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. | Deposit date: | 2008-03-02 | Release date: | 2008-06-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin. Mol.Cell, 30, 2008
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5FLX
| Mammalian 40S HCV-IRES complex | Descriptor: | 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... | Authors: | Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T. | Deposit date: | 2015-10-28 | Release date: | 2015-12-23 | Last modified: | 2017-08-30 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA. Embo J., 34, 2015
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3RGW
| Crystal structure at 1.5 A resolution of an H2-reduced, O2-tolerant hydrogenase from Ralstonia eutropha unmasks a novel iron-sulfur cluster | Descriptor: | FE3-S4 CLUSTER, FE4-S3 CLUSTER, IRON/SULFUR CLUSTER, ... | Authors: | Scheerer, P, Fritsch, J, Frielingsdorf, S, Kroschinsky, S, Friedrich, B, Lenz, O, Spahn, C.M.T. | Deposit date: | 2011-04-10 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre. Nature, 479, 2011
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6GBZ
| 50S ribosomal subunit assembly intermediate state 5 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T. | Deposit date: | 2018-04-16 | Release date: | 2018-06-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution. Mol. Cell, 70, 2018
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6GC8
| 50S ribosomal subunit assembly intermediate - 50S rec* | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T. | Deposit date: | 2018-04-17 | Release date: | 2018-06-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution. Mol. Cell, 70, 2018
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7ZJX
| Rabbit 80S ribosome programmed with SECIS and SBP2 | Descriptor: | 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ... | Authors: | Hilal, T, Simonovic, M, Spahn, C.M.T. | Deposit date: | 2022-04-12 | Release date: | 2022-09-07 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Science, 376, 2022
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7ZJW
| Rabbit 80S ribosome as it decodes the Sec-UGA codon | Descriptor: | 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ... | Authors: | Hilal, T, Simonovic, M, Spahn, C.M.T. | Deposit date: | 2022-04-12 | Release date: | 2022-10-19 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Science, 376, 2022
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1EG0
| FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME | Descriptor: | FORMYL-METHIONYL-TRNA, FRAGMENT OF 16S RRNA HELIX 23, FRAGMENT OF 23S RRNA, ... | Authors: | Gabashvili, I.S, Agrawal, R.K, Spahn, C.M.T, Grassucci, R.A, Svergun, D.I, Frank, J, Penczek, P. | Deposit date: | 2000-02-11 | Release date: | 2000-03-06 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (11.5 Å) | Cite: | Solution structure of the E. coli 70S ribosome at 11.5 A resolution. Cell(Cambridge,Mass.), 100, 2000
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2NOQ
| Structure of ribosome-bound cricket paralysis virus IRES RNA | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S5, ... | Authors: | Schuler, M, Connell, S.R, Lescoute, A, Giesebrecht, J, Dabrowski, M, Schroeer, B, Mielke, T, Penczek, P.A, Westhof, E, Spahn, C.M.T. | Deposit date: | 2006-10-26 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Structure of the ribosome-bound cricket paralysis virus IRES RNA. Nat.Struct.Mol.Biol., 13, 2006
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2OM7
| Structural Basis for Interaction of the Ribosome with the Switch Regions of GTP-bound Elongation Factors | Descriptor: | 16S ribosomal RNA (H5), 30S ribosomal protein S12, 30S ribosomal protein S2, ... | Authors: | Connell, S.R, Wilson, D.N, Rost, M, Schueler, M, Giesebrecht, J, Dabrowski, M, Mielke, T, Fucini, P, Spahn, C.M.T. | Deposit date: | 2007-01-21 | Release date: | 2008-01-15 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors. Mol.Cell, 25, 2007
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1FCW
| TRNA POSITIONS DURING THE ELONGATION CYCLE | Descriptor: | TRNAPHE | Authors: | Agrawal, R.K, Spahn, C.M.T, Penczek, P, Grassucci, R.A, Nierhaus, K.H, Frank, J. | Deposit date: | 2000-07-19 | Release date: | 2000-08-11 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (17 Å) | Cite: | Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle. J.Cell Biol., 150, 2000
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2IX8
| MODEL FOR EEF3 BOUND TO AN 80S RIBOSOME | Descriptor: | ELONGATION FACTOR 3A | Authors: | Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R. | Deposit date: | 2006-07-07 | Release date: | 2007-07-10 | Last modified: | 2017-08-23 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site. Nature, 443, 2006
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2IWH
| Structure of yeast Elongation Factor 3 in complex with ADPNP | Descriptor: | ELONGATION FACTOR 3A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION | Authors: | Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R. | Deposit date: | 2006-06-30 | Release date: | 2006-08-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site. Nature, 443, 2006
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2IX3
| Structure of yeast Elongation Factor 3 | Descriptor: | ELONGATION FACTOR 3, SULFATE ION | Authors: | Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R. | Deposit date: | 2006-07-06 | Release date: | 2006-08-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site. Nature, 443, 2006
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2IW3
| Elongation Factor 3 in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ELONGATION FACTOR 3A, SULFATE ION | Authors: | Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R. | Deposit date: | 2006-06-26 | Release date: | 2006-08-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site. Nature, 443, 2006
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6YGB
| Crystal structure of the NatC complex bound to CoA | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ... | Authors: | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | Deposit date: | 2020-03-27 | Release date: | 2020-10-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.451 Å) | Cite: | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
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6YGA
| Crystal structure of the apo NatC complex | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | Deposit date: | 2020-03-27 | Release date: | 2020-10-28 | Last modified: | 2020-11-18 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
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6YGD
| Crystal structure of the NatC complex bound to Gag peptide and CoA | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ... | Authors: | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | Deposit date: | 2020-03-27 | Release date: | 2020-10-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.752 Å) | Cite: | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
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7BL6
| 50S-ObgE-GMPPNP particle | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T. | Deposit date: | 2021-01-18 | Release date: | 2021-05-12 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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7BL3
| pre-50S-ObgE particle state 2 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | Authors: | Hilal, T, Nikolay, R, Spahn, C.M.T. | Deposit date: | 2021-01-18 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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7BL2
| pre-50S-ObgE particle state 1 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | Authors: | Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T. | Deposit date: | 2021-01-18 | Release date: | 2021-05-12 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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