4MXF
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![BU of 4mxf by Molmil](/molmil-images/mine/4mxf) | |
4RTE
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5L4R
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![BU of 5l4r by Molmil](/molmil-images/mine/5l4r) | X-ray structure of the adduct between thaumatin and cisplatin | Descriptor: | Cisplatin, GLYCEROL, L(+)-TARTARIC ACID, ... | Authors: | Russo Krauss, I, Ferraro, G, Merlino, A. | Deposit date: | 2016-05-26 | Release date: | 2016-12-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Cisplatin-Protein Interactions: Unexpected Drug Binding to N-Terminal Amine and Lysine Side Chains. Inorg.Chem., 55, 2016
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4DIH
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![BU of 4dih by Molmil](/molmil-images/mine/4dih) | X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of sodium ions | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | Authors: | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2012-01-31 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity. Nucleic Acids Res., 40, 2012
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5DWW
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5CMX
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![BU of 5cmx by Molmil](/molmil-images/mine/5cmx) | X-ray structure of the complex between human alpha thrombin and a duplex/quadruplex 31-mer DNA aptamer | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, RE31, ... | Authors: | Russo Krauss, I, Pica, A, Napolitano, V, Sica, F. | Deposit date: | 2015-07-17 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Different duplex/quadruplex junctions determine the properties of anti-thrombin aptamers with mixed folding. Nucleic Acids Res., 44, 2016
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4DII
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![BU of 4dii by Molmil](/molmil-images/mine/4dii) | X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of potassium ions | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | Authors: | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2012-01-31 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity. Nucleic Acids Res., 40, 2012
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3QLP
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![BU of 3qlp by Molmil](/molmil-images/mine/3qlp) | X-ray structure of the complex between human alpha thrombin and a modified thrombin binding aptamer (mTBA) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ... | Authors: | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2011-02-03 | Release date: | 2011-10-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Thrombin-aptamer recognition: a revealed ambiguity. Nucleic Acids Res., 39, 2011
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4YIO
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![BU of 4yio by Molmil](/molmil-images/mine/4yio) | X-ray structure of the iron/manganese cambialistic superoxide dismutase from Streptococcus thermophilus | Descriptor: | FE (III) ION, GLYCEROL, SULFATE ION, ... | Authors: | Russo Krauss, I, Merlino, A, Pica, A, Sica, F. | Deposit date: | 2015-03-02 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Fine tuning of metal-specific activity in the Mn-like group of cambialistic superoxide dismutases Rsc Adv, 5, 2015
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4YIP
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![BU of 4yip by Molmil](/molmil-images/mine/4yip) | X-ray structure of the iron/manganese cambialistic superoxide dismutase from Streptococcus mutans | Descriptor: | FE (III) ION, Superoxide dismutase [Mn/Fe] | Authors: | Russo Krauss, I, Merlino, A, Pica, A, Sica, F. | Deposit date: | 2015-03-02 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Fine tuning of metal-specific activity in the Mn-like group of cambialistic superoxide dismutases Rsc Adv, 5, 2015
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3LN8
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![BU of 3ln8 by Molmil](/molmil-images/mine/3ln8) | The X-ray structure of Zf-RNase-1 from a new crystal form at pH 7.3 | Descriptor: | HYDROLASE, SULFATE ION | Authors: | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2010-02-02 | Release date: | 2010-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish. Biochem.J., 433, 2010
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3LJD
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![BU of 3ljd by Molmil](/molmil-images/mine/3ljd) | The X-ray structure of zebrafish RNase1 from a new crystal form at pH 4.5 | Descriptor: | ACETATE ION, SULFATE ION, Zebrafish RNase1 | Authors: | Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2010-01-26 | Release date: | 2010-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish. Biochem.J., 433, 2010
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5F9U
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![BU of 5f9u by Molmil](/molmil-images/mine/5f9u) | X-RAY STRUCTURE OF THE ADDUCT BETWEEN HEN EGG WHITE LYSOZYME AND CISPLATIN UPON 24 HOURS OF INCUBATION AT 20 DEGREES | Descriptor: | Cisplatin, GLYCEROL, Lysozyme C | Authors: | Russo Krauss, I, Ferraro, G, Pica, A, Merlino, A. | Deposit date: | 2015-12-10 | Release date: | 2016-04-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Effect of temperature on the interaction of cisplatin with the model protein hen egg white lysozyme. J.Biol.Inorg.Chem., 21, 2016
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5FCP
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![BU of 5fcp by Molmil](/molmil-images/mine/5fcp) | X-RAY STRUCTURE OF THE ADDUCT BETWEEN HEN EGG WHITE LYSOZYME AND CISPLATIN AT LONG INCUBATION TIMES | Descriptor: | CHLORIDE ION, Cisplatin, GLYCEROL, ... | Authors: | Russo Krauss, I, Ferraro, G, Pica, A, Merlino, A. | Deposit date: | 2015-12-15 | Release date: | 2016-04-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Effect of temperature on the interaction of cisplatin with the model protein hen egg white lysozyme. J.Biol.Inorg.Chem., 21, 2016
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5F9X
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![BU of 5f9x by Molmil](/molmil-images/mine/5f9x) | X-RAY STRUCTURE OF THE ADDUCT BETWEEN HEN EGG WHITE LYSOZYME AND CISPLATIN UPON 24 HOURS OF INCUBATION AT 55 DEGREES | Descriptor: | Cisplatin, GLYCEROL, Lysozyme C | Authors: | Russo Krauss, I, Ferraro, G, Pica, A, Merlino, A. | Deposit date: | 2015-12-10 | Release date: | 2016-04-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Effect of temperature on the interaction of cisplatin with the model protein hen egg white lysozyme. J.Biol.Inorg.Chem., 21, 2016
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3LJE
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![BU of 3lje by Molmil](/molmil-images/mine/3lje) | The X-ray structure of zebrafish RNase5 | Descriptor: | ACETATE ION, SULFATE ION, Zebrafish RNase5 | Authors: | Russo Krauss, I, Merlino, A, Coscia, F, Mazzarella, L, Sica, F. | Deposit date: | 2010-01-26 | Release date: | 2010-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish. Biochem.J., 433, 2010
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4QH3
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![BU of 4qh3 by Molmil](/molmil-images/mine/4qh3) | |
4QY9
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![BU of 4qy9 by Molmil](/molmil-images/mine/4qy9) | X-ray structure of the adduct between hen egg white lysozyme and Auoxo3, a cytotoxic gold(III) compound | Descriptor: | 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ... | Authors: | Russo Krauss, I, Merlino, A. | Deposit date: | 2014-07-24 | Release date: | 2014-11-05 | Last modified: | 2014-11-19 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Interactions of gold-based drugs with proteins: the structure and stability of the adduct formed in the reaction between lysozyme and the cytotoxic gold(iii) compound Auoxo3. Dalton Trans, 43, 2014
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4QGZ
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![BU of 4qgz by Molmil](/molmil-images/mine/4qgz) | |
4L2C
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![BU of 4l2c by Molmil](/molmil-images/mine/4l2c) | |
4L2D
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4L0A
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![BU of 4l0a by Molmil](/molmil-images/mine/4l0a) | X-ray structure of an all LNA quadruplex | Descriptor: | DNA/RNA (5'-R(*(TLN)P*(LCG)P*(LCG)P*(LCG)P*(TLN))-3'), GLYCEROL, POTASSIUM ION | Authors: | Russo Krauss, I, Parkinson, G, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2013-05-31 | Release date: | 2014-03-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A regular thymine tetrad and a peculiar supramolecular assembly in the first crystal structure of an all-LNA G-quadruplex. Acta Crystallogr.,Sect.D, 70, 2014
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4I7Y
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![BU of 4i7y by Molmil](/molmil-images/mine/4i7y) | Crystal Structure of Human Alpha Thrombin in Complex with a 27-mer Aptamer Bound to Exosite II | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, DNA (27-MER), ... | Authors: | Pica, A, Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2012-12-01 | Release date: | 2013-10-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Duplex-quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer. Acta Crystallogr.,Sect.D, 69, 2013
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5EW1
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![BU of 5ew1 by Molmil](/molmil-images/mine/5ew1) | Human thrombin sandwiched between two DNA aptamers: HD22 and HD1-deltaT3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, HD1-deltaT3, ... | Authors: | Pica, A, Russo Krauss, I, Parente, V, Sica, F. | Deposit date: | 2015-11-20 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers. Nucleic Acids Res., 45, 2017
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5EW2
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![BU of 5ew2 by Molmil](/molmil-images/mine/5ew2) | Human thrombin sandwiched between two DNA aptamers: HD22 and HD1-deltaT12 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, HD1-deltaT12, ... | Authors: | Pica, A, Russo Krauss, I, Parente, V, Sica, F. | Deposit date: | 2015-11-20 | Release date: | 2016-11-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers. Nucleic Acids Res., 45, 2017
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