Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 167 results

6IAF
DownloadVisualize
BU of 6iaf by Molmil
Fifteen minutes iron loaded Rana Catesbeiana H' ferritin variant H54N
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S.
Deposit date:2018-11-26
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H' ferritin.
J.Inorg.Biochem., 197, 2019
6IAJ
DownloadVisualize
BU of 6iaj by Molmil
Sixty minutes iron loaded Rana Catesbeiana H' ferritin variant H54N
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S.
Deposit date:2018-11-26
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H' ferritin.
J.Inorg.Biochem., 197, 2019
4O1X
DownloadVisualize
BU of 4o1x by Molmil
Crystal structure of human thymidylate synthase double mutant C195S-Y202C
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ...
Authors:Pozzi, C, Mangani, S.
Deposit date:2013-12-16
Release date:2015-01-21
Last modified:2023-03-01
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Elife, 11, 2022
4O1U
DownloadVisualize
BU of 4o1u by Molmil
Crystal structure of human thymidylate synthase mutant Y202C
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ...
Authors:Pozzi, C, Mangani, S.
Deposit date:2013-12-16
Release date:2015-01-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Elife, 11, 2022
5J93
DownloadVisualize
BU of 5j93 by Molmil
Five minutes iron loaded Rana Catesbeiana H' ferritin variant E57A/E136A/D140A
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S, Bernacchioni, C, Turano, P.
Deposit date:2016-04-08
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity.
Chemistry, 22, 2016
5J8S
DownloadVisualize
BU of 5j8s by Molmil
Iron-free state of Rana Catesbeiana H' ferritin variant E57A/E136A/D140A
Descriptor: CHLORIDE ION, Ferritin, middle subunit, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S, Bernacchioni, C, Turano, P.
Deposit date:2016-04-08
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity.
Chemistry, 22, 2016
5J9V
DownloadVisualize
BU of 5j9v by Molmil
Ten minutes iron loaded Rana Catesbeiana H' ferritin variant E57A/E136A/D140A
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S, Bernacchioni, C, Turano, P.
Deposit date:2016-04-11
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity.
Chemistry, 22, 2016
5J8W
DownloadVisualize
BU of 5j8w by Molmil
One minute iron loaded Rana Catesbeiana H' ferritin variant E57A/E136A/D140A
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S, Bernacchioni, C, Turano, P.
Deposit date:2016-04-08
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity.
Chemistry, 22, 2016
5JAC
DownloadVisualize
BU of 5jac by Molmil
Sixty minutes iron loaded Rana Catesbeiana H' ferritin variant E57A/E136A/D140A
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S, Bernacchioni, C, Turano, P.
Deposit date:2016-04-12
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity.
Chemistry, 22, 2016
4KPW
DownloadVisualize
BU of 4kpw by Molmil
Crystal structure of His-tagged human thymidylate synthase R175A mutant
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase
Authors:Pozzi, C, Mangani, S.
Deposit date:2013-05-14
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase.
J.Med.Chem., 58, 2015
5LG2
DownloadVisualize
BU of 5lg2 by Molmil
Horse L type ferritin iron loaded for 60 minutes
Descriptor: CADMIUM ION, CHLORIDE ION, FE (III) ION, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S.
Deposit date:2016-07-05
Release date:2017-02-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Chemistry at the protein-mineral interface in L-ferritin assists the assembly of a functional ( mu (3)-oxo)Tris[( mu (2)-peroxo)] triiron(III) cluster.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LG8
DownloadVisualize
BU of 5lg8 by Molmil
Human L-type ferritin iron loaded for 60 minutes
Descriptor: CADMIUM ION, FE (III) ION, Ferritin light chain, ...
Authors:Pozzi, C, Di Pisa, F, Mangani, S.
Deposit date:2016-07-06
Release date:2017-02-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Chemistry at the protein-mineral interface in L-ferritin assists the assembly of a functional ( mu (3)-oxo)Tris[( mu (2)-peroxo)] triiron(III) cluster.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ZXO
DownloadVisualize
BU of 6zxo by Molmil
Crystal structure of His-tagged human thymidylate synthase (HT-hTS) in complex with FdUMP and Raltitrexed (Tomudex)
Descriptor: 1,2-ETHANEDIOL, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, TOMUDEX, ...
Authors:Pozzi, C, Mangani, S.
Deposit date:2020-07-30
Release date:2021-05-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations.
Cancers (Basel), 13, 2021
5IZC
DownloadVisualize
BU of 5izc by Molmil
Trypanosoma brucei PTR1 in complex with inhibitor F032
Descriptor: ACETATE ION, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Pozzi, C, Landi, G, Di Pisa, F, Mangani, S.
Deposit date:2016-03-25
Release date:2017-04-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery.
ACS Omega, 2, 2017
7O66
DownloadVisualize
BU of 7o66 by Molmil
Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 60 minutes showing either a dioxygen or a superoxide anion coordinated to iron ions in the ferroxidase site
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S.
Deposit date:2021-04-09
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021
7O65
DownloadVisualize
BU of 7o65 by Molmil
Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 90 minutes showing either a dioxygen or a superoxide anion coordinated to iron ions in the ferroxidase site
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S.
Deposit date:2021-04-09
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021
7O64
DownloadVisualize
BU of 7o64 by Molmil
Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 1 minute.
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S.
Deposit date:2021-04-09
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021
7O6C
DownloadVisualize
BU of 7o6c by Molmil
Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 15 minutes under anaerobic environment
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S.
Deposit date:2021-04-09
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021
7O63
DownloadVisualize
BU of 7o63 by Molmil
High resolution crystal structure of human mitochondrial ferritin (hMTF)
Descriptor: CHLORIDE ION, Ferritin, mitochondrial, ...
Authors:Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S.
Deposit date:2021-04-09
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021
7O68
DownloadVisualize
BU of 7o68 by Molmil
Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 120 minutes showing either a dioxygen or a superoxide anion coordinated to iron ions in the ferroxidase site.
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S.
Deposit date:2021-04-09
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021
7O6A
DownloadVisualize
BU of 7o6a by Molmil
Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 5 minutes under anaerobic environment
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S.
Deposit date:2021-04-09
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021
7O6D
DownloadVisualize
BU of 7o6d by Molmil
Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 3 minutes under anaerobic environment
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S.
Deposit date:2021-04-09
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021
7O69
DownloadVisualize
BU of 7o69 by Molmil
Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 5 minutes showing a peroxide anion as bridging species of iron ions in the ferroxidase site
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S.
Deposit date:2021-04-09
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021
7O67
DownloadVisualize
BU of 7o67 by Molmil
Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 15 minutes showing either a dioxygen or a superoxide anion coordinated to iron ions in the ferroxidase site
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S.
Deposit date:2021-04-09
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021
7OWY
DownloadVisualize
BU of 7owy by Molmil
Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 3 minutes showing a peroxide anion as bridging species of iron ions in the ferroxidase site
Descriptor: CHLORIDE ION, FE (II) ION, Ferritin, ...
Authors:Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S.
Deposit date:2021-06-21
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Chemistry, 27, 2021

224201

PDB entries from 2024-08-28

PDB statisticsPDBj update infoContact PDBjnumon