1YE3
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6OWP
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![BU of 6owp by Molmil](/molmil-images/mine/6owp) | Horse liver F93W alcohol dehydrogenase complexed with NAD and trifluoroethanol | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Alcohol dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... | 著者 | Plapp, B.V. | 登録日 | 2019-05-10 | 公開日 | 2019-05-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Substitutions of Amino Acid Residues in the Substrate Binding Site of Horse Liver Alcohol Dehydrogenase Have Small Effects on the Structures but Significantly Affect Catalysis of Hydrogen Transfer. Biochemistry, 59, 2020
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4W6Z
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![BU of 4w6z by Molmil](/molmil-images/mine/4w6z) | YEAST ALCOHOL DEHYDROGENASE I, SACCHAROMYCES CEREVISIAE FERMENTATIVE ENZYME | 分子名称: | Alcohol dehydrogenase 1, NICOTINAMIDE-8-IODO-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL, ... | 著者 | plapp, B.v, savarimuthu, b.r, ramaswamy, s. | 登録日 | 2014-08-21 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Yeast alcohol dehydrogenase structure and catalysis. Biochemistry, 53, 2014
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6XT2
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![BU of 6xt2 by Molmil](/molmil-images/mine/6xt2) | EQADH-NADH-HEPTAFLUOROBUTANOL, P21 | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2,2,3,3,4,4,4-heptafluorobutan-1-ol, ... | 著者 | Plapp, B.V, Ramaswamy, S. | 登録日 | 2020-07-16 | 公開日 | 2020-08-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Alternative binding modes in abortive NADH-alcohol complexes of horse liver alcohol dehydrogenase. Arch.Biochem.Biophys., 701, 2021
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5ENV
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![BU of 5env by Molmil](/molmil-images/mine/5env) | YEAST ALCOHOL DEHYDROGENASE WITH BOUND COENZYME | 分子名称: | Alcohol dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL, ... | 著者 | Plapp, B.V, Charlier Jr, H.A, Ramaswamy, S. | 登録日 | 2015-11-09 | 公開日 | 2015-11-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Mechanistic implications from structures of yeast alcohol dehydrogenase complexed with coenzyme and an alcohol. Arch.Biochem.Biophys., 591, 2015
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3OQ6
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![BU of 3oq6 by Molmil](/molmil-images/mine/3oq6) | Horse liver alcohol dehydrogenase A317C mutant complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ... | 著者 | Plapp, B.V, Herdendorf, T.J. | 登録日 | 2010-09-02 | 公開日 | 2010-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Origins of the high catalytic activity of human alcohol dehydrogenase 4 studied with horse liver A317C alcohol dehydrogenase. Chem.Biol.Interact, 191, 2011
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4DWV
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![BU of 4dwv by Molmil](/molmil-images/mine/4dwv) | Horse alcohol dehydrogenase complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ... | 著者 | Plapp, B.V, Ramaswamy, S. | 登録日 | 2012-02-26 | 公開日 | 2012-04-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Atomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD(+) and Fluoroalcohols Define Strained Michaelis Complexes. Biochemistry, 51, 2012
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4DXH
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![BU of 4dxh by Molmil](/molmil-images/mine/4dxh) | Horse liver alcohol dehydrogenase complexed with NAD+ and 2,2,2-trifluoroethanol | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Alcohol dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... | 著者 | Plapp, B.V, Ramaswamy, S. | 登録日 | 2012-02-27 | 公開日 | 2012-04-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Atomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD(+) and Fluoroalcohols Define Strained Michaelis Complexes. Biochemistry, 51, 2012
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6OWM
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![BU of 6owm by Molmil](/molmil-images/mine/6owm) | Horse liver F93W alcohol dehydrogenase complexed with NAD and pentafluorobenzyl alcohol | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ... | 著者 | Plapp, B.V. | 登録日 | 2019-05-10 | 公開日 | 2019-05-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Substitutions of Amino Acid Residues in the Substrate Binding Site of Horse Liver Alcohol Dehydrogenase Have Small Effects on the Structures but Significantly Affect Catalysis of Hydrogen Transfer. Biochemistry, 59, 2020
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6O91
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![BU of 6o91 by Molmil](/molmil-images/mine/6o91) | Horse liver L57F alcohol dehydrogenase complexed with NAD and pentafluorobenzyl alcohol | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ... | 著者 | Plapp, B.V. | 登録日 | 2019-03-12 | 公開日 | 2019-04-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Substitutions of Amino Acid Residues in the Substrate Binding Site of Horse Liver Alcohol Dehydrogenase Have Small Effects on the Structures but Significantly Affect Catalysis of Hydrogen Transfer. Biochemistry, 59, 2020
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6OA7
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![BU of 6oa7 by Molmil](/molmil-images/mine/6oa7) | Horse liver L57F alcohol dehydrogenase E complexed with NAD and trifluoroethanol | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Alcohol dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... | 著者 | Plapp, B.V. | 登録日 | 2019-03-15 | 公開日 | 2019-04-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Substitutions of Amino Acid Residues in the Substrate Binding Site of Horse Liver Alcohol Dehydrogenase Have Small Effects on the Structures but Significantly Affect Catalysis of Hydrogen Transfer. Biochemistry, 59, 2020
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8G41
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![BU of 8g41 by Molmil](/molmil-images/mine/8g41) | Horse liver alcohol dehydrogense His-51-Gln form complexed with NADH | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Plapp, B.V. | 登録日 | 2023-02-08 | 公開日 | 2023-02-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Histidine-51 facilitates deprotonatation of the zinc-bound ligand during catalysis by horse liver alcohol dehydrogenase To Be Published
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8G2X
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4XD2
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![BU of 4xd2 by Molmil](/molmil-images/mine/4xd2) | Horse liver alcohol dehydrogenase-NADH complex | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Alcohol dehydrogenase E chain, ... | 著者 | Plapp, B.V, Baskar Raj, S, Ferraro, D.J. | 登録日 | 2014-12-18 | 公開日 | 2015-01-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Structure of Horse liver alcohol dehydrogenase complexed with NADH To Be Published
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5VN1
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![BU of 5vn1 by Molmil](/molmil-images/mine/5vn1) | horse liver alcohol dehydrogenae complexed with NADH (R,S)-N-1-methylhexylformamide | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (R)-N-(1-METHYL-HEXYL)-FORMAMIDE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Plapp, B.V, Ramaswamy, S, Ferraro, D.J, Baskar Raj, S. | 登録日 | 2017-04-28 | 公開日 | 2017-05-10 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis. Biochemistry, 56, 2017
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8G2L
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8G4V
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![BU of 8g4v by Molmil](/molmil-images/mine/8g4v) | Horse liver alcohol dehydrogense His-51-Gln form complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ... | 著者 | Plapp, B.V, Subramanian, R. | 登録日 | 2023-02-10 | 公開日 | 2023-02-22 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Histidine-51 facilitates deprotonation of the zinc-bound ligand during catalysis by horse liver alcohol dehydrogenase To Be Published
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8G2S
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8G39
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6CY3
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![BU of 6cy3 by Molmil](/molmil-images/mine/6cy3) | Horse liver E267N alcohol dehydrogenase complex with 3'-dephosphocoenzyme A | 分子名称: | DEPHOSPHO COENZYME A, ZINC ION, alcohol dehydrogenase | 著者 | Plapp, B.V. | 登録日 | 2018-04-04 | 公開日 | 2018-04-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Substitutions of a buried glutamate residue hinder the conformational change in horse liver alcohol dehydrogenase and yield a surprising complex with endogenous 3'-Dephosphocoenzyme A. Arch. Biochem. Biophys., 653, 2018
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6CXX
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![BU of 6cxx by Molmil](/molmil-images/mine/6cxx) | Horse liver E267H alcohol dehydrogenase complex with 3'-dephosphocoenzyme A | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Alcohol dehydrogenase E chain, ... | 著者 | Plapp, B.V. | 登録日 | 2018-04-04 | 公開日 | 2018-04-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Substitutions of a buried glutamate residue hinder the conformational change in horse liver alcohol dehydrogenase and yield a surprising complex with endogenous 3'-Dephosphocoenzyme A. Arch. Biochem. Biophys., 653, 2018
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7K35
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![BU of 7k35 by Molmil](/molmil-images/mine/7k35) | EQADH-NADH-4-METHYLBENZYL ALCOHOL, p21 | 分子名称: | (4-methylphenyl)methanol, (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Plapp, B.V, Ramaswamy, S. | 登録日 | 2020-09-10 | 公開日 | 2020-09-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Alternative binding modes in abortive NADH-alcohol complexes of horse liver alcohol dehydrogenase. Arch.Biochem.Biophys., 701, 2021
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4NFH
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![BU of 4nfh by Molmil](/molmil-images/mine/4nfh) | V207A Horse Liver Alcohol Dehydrogenase E complexed with NAD and 2,3,4,5,6-pentafluorobenzyl alcohol | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ... | 著者 | Plapp, B.V. | 登録日 | 2013-10-31 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Effects of cavities at the nicotinamide binding site of liver alcohol dehydrogenase on structure, dynamics and catalysis. Biochemistry, 53, 2014
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4NFS
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![BU of 4nfs by Molmil](/molmil-images/mine/4nfs) | V203A horse liver alcohol dehydrogenase E complexed with NAD and 2,2,2-trifluoroethanol | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Alcohol dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... | 著者 | Plapp, B.V. | 登録日 | 2013-10-31 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Effects of cavities at the nicotinamide binding site of liver alcohol dehydrogenase on structure, dynamics and catalysis. Biochemistry, 53, 2014
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7JQA
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![BU of 7jqa by Molmil](/molmil-images/mine/7jqa) | EQADH-NADH-4-BROMOBENZYL ALCOHOL, P21 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Alcohol dehydrogenase E chain, ... | 著者 | Plapp, B.V, Ramaswamy, S. | 登録日 | 2020-08-10 | 公開日 | 2020-08-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Alternative binding modes in abortive NADH-alcohol complexes of horse liver alcohol dehydrogenase. Arch.Biochem.Biophys., 701, 2021
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