3QGA
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6XRG
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2VPE
| Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | Descriptor: | B-CELL CLL/LYMPHOMA 9 PROTEIN, GLYCEROL, HISTONE H3 TAIL, ... | Authors: | Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M. | Deposit date: | 2008-02-27 | Release date: | 2008-06-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex. Mol.Cell, 30, 2008
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5YUF
| Crystal Structure of PML RING tetramer | Descriptor: | Protein PML, ZINC ION | Authors: | Wang, P, Benhend, S, Wu, H, Breitenbach, V, Zhen, T, Jollivet, F, Peres, L, Li, Y, Chen, S, Chen, Z, de THE, H, Meng, G. | Deposit date: | 2017-11-22 | Release date: | 2018-04-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | RING tetramerization is required for nuclear body biogenesis and PML sumoylation. Nat Commun, 9, 2018
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7RUO
| Crystal structure of human UTP15 | Descriptor: | U3 small nucleolar RNA-associated protein 15 homolog, UNKNOWN ATOM OR ION | Authors: | Dehghani-Tafti, S, Dong, A, Zeng, H, Hutchinson, A, Seitova, A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | Deposit date: | 2021-08-17 | Release date: | 2021-11-10 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of human UTP15 To Be Published
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5Z18
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2PNJ
| Crystal structure of human ferrochelatase mutant with Phe 337 replaced by Ala | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | Authors: | Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, W, Burden, A.E, Dailey, T.A, Rose, J.P. | Deposit date: | 2007-04-24 | Release date: | 2007-10-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis Biochemistry, 46, 2007
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7XU2
| Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | Deposit date: | 2022-05-18 | Release date: | 2022-07-20 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. Plos Pathog., 18, 2022
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2PPS
| PHOTOSYNTHETIC REACTION CENTER AND CORE ANTENNA SYSTEM (TRIMERIC), ALPHA CARBON ONLY | Descriptor: | CHLOROPHYLL A, IRON/SULFUR CLUSTER, PHOTOSYSTEM I, ... | Authors: | Krauss, N, Schubert, W.-D, Klukas, O, Fromme, P, Witt, H.T, Saenger, W. | Deposit date: | 1997-05-27 | Release date: | 1998-05-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Photosystem I at 4 A resolution represents the first structural model of a joint photosynthetic reaction centre and core antenna system. Nat.Struct.Biol., 3, 1996
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5Z6H
| Structure of periplasmic trehalase from Diamondback moth gut bacteria in the apo form | Descriptor: | GLYCEROL, Periplasmic trehalase, SULFATE ION | Authors: | Harne, S.R, Adhav, A.S, Joshi, R.S, Gayathri, P. | Deposit date: | 2018-01-22 | Release date: | 2019-01-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mechanistic insights into enzymatic catalysis by trehalase from the insect gut endosymbiont Enterobacter cloacae. Febs J., 286, 2019
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2WXI
| The crystal structure of the murine class IA PI 3-kinase p110delta in complex with SW30. | Descriptor: | 2-{[4-amino-3-(3-hydroxyprop-1-yn-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-5-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one, GLYCEROL, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | Authors: | Berndt, A, Miller, S, Williams, O, Lee, D.D, Houseman, B.T, Pacold, J.I, Gorrec, F, Hon, W.-C, Liu, Y, Rommel, C, Gaillard, P, Ruckle, T, Schwarz, M.K, Shokat, K.M, Shaw, J.P, Williams, R.L. | Deposit date: | 2009-11-09 | Release date: | 2010-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors Nat.Chem.Biol., 6, 2010
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2WXN
| The crystal structure of the murine class IA PI 3-kinase p110delta in complex with DL07. | Descriptor: | 3-{[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl}phenol, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | Authors: | Berndt, A, Miller, S, Williams, O, Lee, D.D, Houseman, B.T, Pacold, J.I, Gorrec, F, Hon, W.-C, Liu, Y, Rommel, C, Gaillard, P, Ruckle, T, Schwarz, M.K, Shokat, K.M, Shaw, J.P, Williams, R.L. | Deposit date: | 2009-11-09 | Release date: | 2010-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors Nat.Chem.Biol., 6, 2010
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4NWR
| Computationally Designed Two-Component Self-Assembling Tetrahedral Cage T33-28 | Descriptor: | Macrophage migration inhibitory factor-like protein, integron gene cassette protein | Authors: | McNamara, D.E, King, N.P, Bale, J.B, Sheffler, W, Baker, D, Yeates, T.O. | Deposit date: | 2013-12-06 | Release date: | 2014-05-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Accurate design of co-assembling multi-component protein nanomaterials. Nature, 510, 2014
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1YCE
| Structure of the rotor ring of F-type Na+-ATPase from Ilyobacter tartaricus | Descriptor: | NONAN-1-OL, SODIUM ION, subunit c | Authors: | Meier, T, Polzer, P, Diederichs, K, Welte, W, Dimroth, P. | Deposit date: | 2004-12-22 | Release date: | 2005-04-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the rotor ring of F-Type Na+-ATPase from Ilyobacter tartaricus. Science, 308, 2005
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8OQW
| Crystal structure of Tannerella forsythia MurNAc kinase MurK | Descriptor: | ATPase, GLYCEROL, SULFATE ION | Authors: | Gogler, K, Fink, P, Stasiak, A.C, Stehle, T, Zocher, G. | Deposit date: | 2023-04-12 | Release date: | 2023-08-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | N-acetylmuramic acid recognition by MurK kinase from the MurNAc auxotrophic oral pathogen Tannerella forsythia. J.Biol.Chem., 299, 2023
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6YB7
| SARS-CoV-2 main protease with unliganded active site (2019-nCoV, coronavirus disease 2019, COVID-19). | Descriptor: | 3C-like proteinase, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE | Authors: | Owen, C.D, Lukacik, P, Strain-Damerell, C.M, Douangamath, A, Powell, A.J, Fearon, D, Brandao-Neto, J, Crawshaw, A.D, Aragao, D, Williams, M, Flaig, R, Hall, D.R, McAuley, K.E, Mazzorana, M, Stuart, D.I, von Delft, F, Walsh, M.A. | Deposit date: | 2020-03-16 | Release date: | 2020-03-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | COVID-19 main protease with unliganded active site To Be Published
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6RW7
| An AA10 LPMO from the shipworm symbiont Teredinibacter turnerae | Descriptor: | COPPER (I) ION, COPPER (II) ION, Carbohydrate binding module family 33 and 10 domain protein, ... | Authors: | Fowler, C.A, Sabbadin, F, Ciano, L, Hemsworth, G.R, Elias, L, Bruce, N.C, McQueen-Mason, S, Walton, P, Davies, G.J. | Deposit date: | 2019-06-04 | Release date: | 2019-10-09 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Discovery, activity and characterisation of an AA10 lytic polysaccharide oxygenase from the shipworm symbiontTeredinibacter turnerae. Biotechnol Biofuels, 12, 2019
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8P5P
| Structure of TECPR1 N-terminal DysF domain | Descriptor: | GLYCEROL, Tectonin beta-propeller repeat-containing protein 1 | Authors: | Boyle, K.B, Elliott, P.R, Randow, F. | Deposit date: | 2023-05-24 | Release date: | 2023-07-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | TECPR1 conjugates LC3 to damaged endomembranes upon detection of sphingomyelin exposure. Embo J., 42, 2023
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1MEU
| HIV-1 MUTANT (V82F, I84V) PROTEASE COMPLEXED WITH DMP323 | Descriptor: | HIV-1 PROTEASE, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHEN YLMETHYL)]-2H-1,3-DIAZEPINONE | Authors: | Ala, P, Chang, C.-H. | Deposit date: | 1997-04-11 | Release date: | 1998-04-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors. Biochemistry, 36, 1997
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6RP6
| Fragment AZ-019 binding at the TAZpS89/14-3-3 sigma interface | Descriptor: | 14-3-3 protein sigma, 4-phenyl-5-(piperidin-4-ylmethyl)thiophene-2-carboximidamide, CALCIUM ION, ... | Authors: | Genet, S, Wolter, M, Guillory, X, Somsen, B, Leysen, S, Patel, J, Castaldi, P, Ottmann, C. | Deposit date: | 2019-05-14 | Release date: | 2020-06-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.885 Å) | Cite: | Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
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2WXK
| The crystal structure of the murine class IA PI 3-kinase p110delta in complex with INK666. | Descriptor: | 3-(2-amino-1,3-benzothiazol-6-yl)-1-{[2-(4-methylpiperazin-1-yl)quinolin-3-yl]methyl}-1H-pyrazolo[3,4-d]pyrimidin-4-amine, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | Authors: | Berndt, A, Miller, S, Williams, O, Lee, D.D, Houseman, B.T, Pacold, J.I, Gorrec, F, Hon, W.-C, Liu, Y, Rommel, C, Gaillard, P, Ruckle, T, Schwarz, M.K, Shokat, K.M, Shaw, J.P, Williams, R.L. | Deposit date: | 2009-11-09 | Release date: | 2010-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors Nat.Chem.Biol., 6, 2010
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2WXM
| The crystal structure of the murine class IA PI 3-kinase p110delta in complex with DL06. | Descriptor: | 1-(1-METHYLETHYL)-3-(PYRIDIN-3-YLETHYNYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | Authors: | Berndt, A, Miller, S, Williams, O, Lee, D.D, Houseman, B.T, Pacold, J.I, Gorrec, F, Hon, W.-C, Liu, Y, Rommel, C, Gaillard, P, Ruckle, T, Schwarz, M.K, Shokat, K.M, Shaw, J.P, Williams, R.L. | Deposit date: | 2009-11-09 | Release date: | 2010-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors Nat.Chem.Biol., 6, 2010
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4F3U
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7XU4
| Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | Deposit date: | 2022-05-18 | Release date: | 2022-07-20 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. Plos Pathog., 18, 2022
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8OJR
| Solution NMR Structure of Alpha-Synuclein 1-25 Peptide in 50% TFE. | Descriptor: | Alpha-synuclein | Authors: | Allen, S.G, Williams, C, Meade, R.M, Tang, T.M.S, Crump, M.P, Mason, J.M. | Deposit date: | 2023-03-24 | Release date: | 2023-08-09 | Method: | SOLUTION NMR | Cite: | An N-terminal alpha-Synuclein fragment binds lipid vesicles to modulate lipid induced aggregation Cell Rep Phys Sci, 2023
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