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PDB: 46226 件

1LCI
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FIREFLY LUCIFERASE
分子名称: LUCIFERASE
著者Conti, E, Franks, N.P, Brick, P.
登録日1996-06-01
公開日1997-03-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes.
Structure, 4, 1996
8B5W
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Crystal structure of the E3 module from UBR4
分子名称: 1,2-ETHANEDIOL, ZINC ION, cDNA FLJ12511 fis, ...
著者Virdee, S, Mabbitt, P.D, Barnsby-Greer, L.
登録日2022-09-24
公開日2023-10-04
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.
Nat.Struct.Mol.Biol., 31, 2024
2HZM
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Structure of the Mediator head subcomplex Med18/20
分子名称: PHOSPHATE ION, RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20
著者Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P.
登録日2006-08-09
公開日2006-09-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
4DJH
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Structure of the human kappa opioid receptor in complex with JDTic
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, CITRIC ACID, ...
著者Wu, H, Wacker, D, Katritch, V, Mileni, M, Han, G.W, Vardy, E, Liu, W, Thompson, A.A, Huang, X.P, Carroll, F.I, Mascarella, S.W, Westkaemper, R.B, Mosier, P.D, Roth, B.L, Cherezov, V, Stevens, R.C, GPCR Network (GPCR)
登録日2012-02-01
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献tructure of the human kappa-opioid receptor in complex with JDTic
Nature, 485, 2012
7WXM
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Crystal Structure of PL-5 family polysaccharide lyase PanPL from Pandoraea apista at pH6.5 in apo form
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, poly(beta-D-mannuronate) lyase
著者Dash, P, Acharya, R.
登録日2022-02-15
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Distinct Modes of Hidden Structural Dynamics in the Functioning of an Allosteric Polysaccharide Lyase.
Acs Cent.Sci., 8, 2022
6UEK
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Structure of Urocanate Hydratase from Trypanosoma cruzi in complex with NAD+
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Urocanate hydratase
著者Boreiko, S, Silva, M, Melo, R.F.P, Silber, A.M, Iulek, J.
登録日2019-09-21
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structure of Urocanate Hydratase from the protozoan Trypanosoma cruzi.
Int.J.Biol.Macromol., 146, 2019
7WXN
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Crystal Structure of PL-5 family polysaccharide lyase PanPL from Pandoraea apista at pH7.5 in apo form
分子名称: poly(beta-D-mannuronate) lyase
著者Dash, P, Acharya, R.
登録日2022-02-15
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Distinct Modes of Hidden Structural Dynamics in the Functioning of an Allosteric Polysaccharide Lyase.
Acs Cent.Sci., 8, 2022
1LSM
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THERMAL STABILITY DETERMINANTS OF CHICKEN EGG-WHITE LYSOZYME CORE MUTANTS: HYDROPHOBICITY, PACKING VOLUME AND CONSERVED BURIED WATER MOLECULES
分子名称: HEN EGG WHITE LYSOZYME
著者Holland, D.R, Shih, P.
登録日1994-09-13
公開日1994-11-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Thermal stability determinants of chicken egg-white lysozyme core mutants: hydrophobicity, packing volume, and conserved buried water molecules.
Protein Sci., 4, 1995
2YOX
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Bacillus amyloliquefaciens CBM33 in complex with Cu(I) after photoreduction
分子名称: COPPER (I) ION, RBAM17540
著者Hemsworth, G.R, Taylor, E.J, Kim, R.Q, Lewis, S.J, Turkenburg, J.P, Davies, G.J, Walton, P.H.
登録日2012-10-29
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Copper Active Site of Cbm33 Polysaccharide Oxygenases.
J.Am.Chem.Soc., 135, 2013
6LD8
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Crystal structure of cystathionine gamma synthase from Xanthomonas oryzae pv. oryzae in complex with aminoacrylate and cysteine
分子名称: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, CYSTEINE, Cystathionine gamma-synthase
著者Ngo, H.P.T, Nguyen, T.D.Q, Kang, L.W.
登録日2019-11-20
公開日2020-11-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of cystathionine gamma synthase from Xanthomonas oryzae pv. oryzae in complex with aminoacrylate and cysteine
To Be Published
2I59
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Solution structure of RGS10
分子名称: Regulator of G-protein signaling 10
著者Fedorov, O, Higman, V.A, Diehl, A, Leidert, M, Lemak, A, Schmieder, P, Oschkinat, H, Elkins, J, Soundarajan, M, Doyle, D.A, Arrowsmith, C, Sundstrom, M, Weigelt, J, Edwards, A, Ball, L.J, Structural Genomics Consortium (SGC)
登録日2006-08-24
公開日2006-10-31
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2E8U
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S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and IPP (P21)
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION
著者Guo, R.T, Chen, C.K.-M, Ko, T.P, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-23
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
6F6R
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Crystal structure of human Caspase-1 with N-{3-[1-((S)-2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-ethyl]-1-methyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl}-4-(quinoxalin-2-ylamino)-benzamide
分子名称: (3~{S})-3-[[(2~{R})-2-[3-methyl-2,6-bis(oxidanylidene)-5-[[4-(quinoxalin-2-ylamino)phenyl]carbonylamino]pyrimidin-1-yl]propanoyl]amino]-4-oxidanyl-butanoic acid, Caspase-1, SULFATE ION
著者Fournier, J.F, Clary, L, Chambon, S, Dumais, L, Harris, C.S, Millois-Barbuis, C, Pierre, R, Talano, S, Thoreau, E, Aubert, J, Aurelly, M, Bouix-Peter, C, Brethon, A, Chantalat, L, Christin, O, Comino, C, El-Bazbouz, G, Ghilini, A.L, Isabet, T, Lardy, C, Luzy, A.P, Mathieu, C, Mebrouk, K, Orfila, D, Pascau, J, Reverse, K, Roche, D, Rodeschini, V, Hennequin, L.F.
登録日2017-12-06
公開日2018-05-02
最終更新日2018-05-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory Acne.
J. Med. Chem., 61, 2018
6F79
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Carboxypeptidase T mutant L211Q with Sulphamoil Arginine
分子名称: CALCIUM ION, Carboxypeptidase T, N~2~-sulfamoyl-L-arginine, ...
著者Timofeev, V.I, Akparov, V.K, Kuranova, I.P.
登録日2017-12-07
公開日2018-08-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Carboxypeptidase T mutant L211Q with Sulphamoil Arginine
To Be Published
2E91
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S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-91
分子名称: Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, ZOLEDRONIC ACID
著者Guo, R.T, Ko, T.P, Cao, R, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
4DOR
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Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, in its apo State Bound to a Fragment of Human SHP Box1
分子名称: L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, Nuclear receptor subfamily 0 group B member 2, Nuclear receptor subfamily 5 group A member 2
著者Musille, P.M, Ortlund, E.A.
登録日2012-02-10
公開日2012-04-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation.
Nat.Struct.Mol.Biol., 19, 2012
6F7T
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Crystal Structure of an Fab fragment in complex with a peptide from Bacillus subtilis RNase Y
分子名称: FAB RY79-90, HEAVY CHAIN, LIGHT CHAIN, ...
著者Golinelli-Pimpaneau, B, Hardouin, P.
登録日2017-12-11
公開日2018-10-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Dissociation of the Dimer of the Intrinsically Disordered Domain of RNase Y upon Antibody Binding.
Biophys. J., 115, 2018
6F6O
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Structure of Adenovirus 3 fiber head V239D mutant
分子名称: Fiber protein
著者Zubieta, C, Fender, P, Stermann, E, Lieber, A.
登録日2017-12-05
公開日2018-12-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Preclinical safety and efficacy studies with an affinity-enhanced epithelial junction opener and PEGylated liposomal doxorubicin.
Mol Ther Methods Clin Dev, 2, 2015
7Y6T
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Cryo-EM map of IPEC-J2 cell-derived PEDV PT52 S protein one D0-down and two D0-up
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hsu, S.T.D, Draczkowski, P, Wang, Y.S.
登録日2022-06-21
公開日2022-08-03
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
2YOW
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Bacillus amyloliquefaciens CBM33
分子名称: RBAM17540
著者Hemsworth, G.R, Taylor, E.J, Kim, R.Q, Lewis, S.J, Turkenburg, J.P, Davies, G.J, Walton, P.H.
登録日2012-10-29
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Copper Active Site of Cbm33 Polysaccharide Oxygenases.
J.Am.Chem.Soc., 135, 2013
6TRN
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Crystal structure of HLA A2*01-AVYDGREHTV
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239) variant, ...
著者Coles, C.H, McMurran, C, Lloyd, A, Hibbert, L, Lupardus, P.J, Cole, D.K, Harper, S.
登録日2019-12-19
公開日2020-06-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4.
J.Biol.Chem., 295, 2020
1LSN
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THERMAL STABILITY DETERMINANTS OF CHICKEN EGG-WHITE LYSOZYME CORE MUTANTS: HYDROPHOBICITY, PACKING VOLUME AND CONSERVED BURIED WATER MOLECULES
分子名称: HEN EGG WHITE LYSOZYME
著者Holland, D.R, Shih, P.
登録日1994-09-13
公開日1994-11-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Thermal stability determinants of chicken egg-white lysozyme core mutants: hydrophobicity, packing volume, and conserved buried water molecules.
Protein Sci., 4, 1995
6TSA
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BU of 6tsa by Molmil
Crystal structure of human L ferritin (HuLf) Fe(III)-loaded for 30 minutes
分子名称: CADMIUM ION, FE (III) ION, Ferritin light chain, ...
著者Pozzi, C, Ciambellotti, S, Turano, P, Mangani, S.
登録日2019-12-20
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin.
Chemistry, 26, 2020
7UH4
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LXG-associated alpha-helical protein D2 (LapD2)
分子名称: LXG-associated alpha-helical protein D2, SULFATE ION
著者Klein, T.A, Grebenc, D.W, Shah, P.Y, McArthur, O.D, Surette, M.G, Kim, Y, Whitney, J.C.
登録日2022-03-25
公開日2022-08-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System.
Mbio, 13, 2022
6TSF
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Crystal structure of human L ferritin (HuLf) Fe(III)-loaded for 60 minutes
分子名称: CADMIUM ION, FE (III) ION, Ferritin light chain, ...
著者Pozzi, C, Ciambellotti, S, Turano, P, Mangani, S.
登録日2019-12-20
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin.
Chemistry, 26, 2020

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