6EJK
 
 | | Structure of a glycosyltransferase | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-glucopyranose, NerylNeryl pyrophosphate, Uridine-Diphosphate-Methylene-N-acetyl-galactosamine, ... | | 著者 | Ramirez, A.S, Boilevin, J, Mehdipour, A.R, Hummer, G, Darbre, T, Reymond, J.L, Locher, K.P. | | 登録日 | 2017-09-21 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis of the molecular ruler mechanism of a bacterial glycosyltransferase.
Nat Commun, 9, 2018
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6SZY
 | | Crystal structure of YTHDC1 with fragment 12 (DHU_DC1_150) | | 分子名称: | 4-propan-2-yl-5,6,7,8-tetrahydro-4~{a}~{H}-quinazolin-2-one, SULFATE ION, YTHDC1 | | 著者 | Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. | | 登録日 | 2019-10-02 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
Acs Chem.Biol., 15, 2020
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6T04
 | | Crystal structure of YTHDC1 with fragment 17 (DHU_DC1_042) | | 分子名称: | 2-phenyl-4,5-dihydro-1~{H}-imidazole, SULFATE ION, YTH domain-containing protein 1 | | 著者 | Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. | | 登録日 | 2019-10-02 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
Acs Chem.Biol., 15, 2020
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7YJ2
 | | Cryo-EM structure of SPT-ORMDL3 (ORMDL3-N13A) complex | | 分子名称: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-19 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
Nat Commun, 14, 2023
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6T12
 | | Crystal structure of YTHDC1 with fragment 30 (DHU_DC1_220) | | 分子名称: | SULFATE ION, YTHDC1, ~{N},2,3-trimethyl-1~{H}-indole-5-carboxamide | | 著者 | Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. | | 登録日 | 2019-10-03 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
Acs Chem.Biol., 15, 2020
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7V6H
 | | Crystal Structure of the SpnL | | 分子名称: | Cyclopropane fatty-acyl-phospholipid synthase-like methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Wu, H.-H, Ko, T.-P, Liu, H.-W, Tsai, M.-D. | | 登録日 | 2021-08-20 | | 公開日 | 2021-12-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.054 Å) | | 主引用文献 | Evidence for an Enzyme-Catalyzed Rauhut-Currier Reaction during the Biosynthesis of Spinosyn A.
J.Am.Chem.Soc., 143, 2021
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7YIU
 | | Cryo-EM structure of the C6-ceramide-bound SPT-ORMDL3 complex | | 分子名称: | HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)HEXANAMIDE, ORM1-like protein 3, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-18 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
Nat Commun, 14, 2023
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6SZ3
 | | Crystal structure of YTHDC1 with fragment 4 (DHU_DC1_158) | | 分子名称: | SULFATE ION, YTH domain-containing protein 1, ~{N}-methyl-5,6,7,8-tetrahydroquinolin-4-amine | | 著者 | Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. | | 登録日 | 2019-10-01 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
Acs Chem.Biol., 15, 2020
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6EI6
 | | CC2D1B coordinates ESRCT-III activity during the mitotic reformation of the nuclear envelope | | 分子名称: | Coiled-coil and C2 domain-containing protein 1-like, DI(HYDROXYETHYL)ETHER, SULFATE ION | | 著者 | Ventimiglia, L.N, Cuesta-Geijo, M.A, Martinelli, N, Caballe, A, Macheboeuf, P, Miguet, N, Parnham, I.M, Olmos, Y, Carlton, J.G, Weissehorn, W, martin-Serrano, J. | | 登録日 | 2017-09-18 | | 公開日 | 2018-10-10 | | 最終更新日 | 2018-12-19 | | 実験手法 | X-RAY DIFFRACTION (2.461 Å) | | 主引用文献 | CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope.
Dev. Cell, 47, 2018
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4DVE
 | | Crystal structure at 2.1 A of the S-component for biotin from an ECF-type ABC transporter | | 分子名称: | BIOTIN, Biotin transporter BioY, nonyl beta-D-glucopyranoside | | 著者 | Berntsson, R.P.-A, ter Beek, J, Majsnerowska, M, Duurkens, R, Puri, P, Poolman, B, Slotboom, D.J. | | 登録日 | 2012-02-23 | | 公開日 | 2012-08-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural divergence of paralogous S components from ECF-type ABC transporters.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2EF9
 | | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P synthase | | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, ARABINOSE-5-PHOSPHATE, PHOSPHOENOLPYRUVATE | | 著者 | Kona, F, Xu, X, Martin, P, Kuzmic, P, Gatti, D.L. | | 登録日 | 2007-02-22 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Mechanistic Changes along an Engineered Path from Metallo to Nonmetallo 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthases
Biochemistry, 46, 2007
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6EIW
 | | Sacbrood virus of honeybee empty particle | | 分子名称: | minor capsid protein MiCP, structural protein VP1, structural protein VP2, ... | | 著者 | Plevka, P, Prochazkova, M. | | 登録日 | 2017-09-19 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Virion structure and genome delivery mechanism of sacbrood honeybee virus.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BC1
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7YIY
 | | Cryo-EM structure of SPT-ORMDL3 complex | | 分子名称: | N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Xie, T, Liu, P, Gong, X. | | 登録日 | 2022-07-18 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
Nat Commun, 14, 2023
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2OWI
 | | Solution structure of the RGS domain from human RGS18 | | 分子名称: | Regulator of G-protein signaling 18 | | 著者 | Higman, V.A, Leidert, M, Bray, J, Elkins, J, Soundararajan, M, Doyle, D.A, Gileadi, C, Phillips, C, Schoch, G, Yang, X, Brockmann, C, Schmieder, P, Diehl, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC) | | 登録日 | 2007-02-16 | | 公開日 | 2007-02-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2J7V
 | | Structure of PBP-A | | 分子名称: | TLL2115 PROTEIN | | 著者 | Evrard, C, Declercq, J.P. | | 登録日 | 2006-10-17 | | 公開日 | 2007-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of Pbp-A from Thermosynechococcus Elongatus, a Penicillin-Binding Protein Closely Related to Class a Beta-Lactamases.
J.Mol.Biol., 386, 2009
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4DJI
 | | Structure of glutamate-GABA antiporter GadC | | 分子名称: | Probable glutamate/gamma-aminobutyrate antiporter | | 著者 | Ma, D, Lu, P.L, Yan, C.Y, Fan, C, Yin, P, Wang, J.W, Shi, Y.G. | | 登録日 | 2012-02-02 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.187 Å) | | 主引用文献 | Structure and mechanism of a glutamate-GABA antiporter
Nature, 483, 2012
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5CLP
 | | Crystal Structure of CK2alpha with 3,4-dichlorophenethylamine bound | | 分子名称: | 2-(3,4-dichlorophenyl)ethanamine, ACETATE ION, Casein kinase II subunit alpha | | 著者 | Brear, P, De Fusco, C, Georgiou, K.H, Spring, D, Hyvonen, M. | | 登録日 | 2015-07-16 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.684 Å) | | 主引用文献 | Specific inhibition of CK2 alpha from an anchor outside the active site.
Chem Sci, 7, 2016
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6T03
 | | Crystal structure of YTHDC1 with fragment 16 (DHU_DC1_017) | | 分子名称: | 1,3-dihydroimidazole-2-thione, SULFATE ION, YTHDC1 | | 著者 | Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. | | 登録日 | 2019-10-02 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
Acs Chem.Biol., 15, 2020
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6ELW
 | | High resolution structure of selenocysteine containing human GPX4 | | 分子名称: | CHLORIDE ION, Phospholipid hydroperoxide glutathione peroxidase, mitochondrial | | 著者 | Kalms, J, Borchert, A, Kuhn, H, Scheerer, P. | | 登録日 | 2017-09-29 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal structure and functional characterization of selenocysteine-containing glutathione peroxidase 4 suggests an alternative mechanism of peroxide reduction.
Biochim. Biophys. Acta, 1863, 2018
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6EO4
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1D6S
 | | CRYSTAL STRUCTURE OF THE K41A MUTANT OF O-ACETYLSERINE SULFHYDRYLASE COMPLEXED IN EXTERNAL ALDIMINE LINKAGE WITH METHIONINE | | 分子名称: | METHIONINE, O-ACETYLSERINE SULFHYDRYLASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Burkhard, P, Tai, C.H, Ristroph, C.M, Cook, P.F, Jansonius, J.N. | | 登録日 | 1999-10-15 | | 公開日 | 2000-04-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Ligand binding induces a large conformational change in O-acetylserine sulfhydrylase from Salmonella typhimurium.
J.Mol.Biol., 291, 1999
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6EPU
 | | The ATAD2 bromodomain in complex with compound 2 | | 分子名称: | (2~{S})-~{N}-(4-ethanoyl-1,3-thiazol-2-yl)piperazine-2-carboxamide, ATPase family AAA domain-containing protein 2, SULFATE ION | | 著者 | Sledz, P, Caflisch, A. | | 登録日 | 2017-10-12 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers.
Acs Med.Chem.Lett., 11, 2020
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6EOY
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6SZ7
 | | Crystal structure of YTHDC1 with fragment 5 (DHU_DC1_066) | | 分子名称: | 5,6,7,8-tetrahydro-4~{a}~{H}-quinazoline-2,4-dione, SULFATE ION, YTH domain-containing protein 1 | | 著者 | Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. | | 登録日 | 2019-10-02 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
Acs Chem.Biol., 15, 2020
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