7W66
 
 | | Crystal structure of a PSH1 mutant in complex with ligand | | 分子名称: | PSH1, bis(2-hydroxyethyl) benzene-1,4-dicarboxylate | | 著者 | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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7W6C
 | | Crystal structure of a PSH1 in complex with ligand J1K | | 分子名称: | 4-(2-hydroxyethylcarbamoyl)benzoic acid, PSH1 | | 著者 | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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1OYB
 | | OLD YELLOW ENZYME AT 2 ANGSTROMS RESOLUTION: OVERALL STRUCTURE, LIGAND BINDING AND COMPARISON WITH RELATED FLAVOPROTEINS | | 分子名称: | FLAVIN MONONUCLEOTIDE, OLD YELLOW ENZYME, P-HYDROXYBENZALDEHYDE | | 著者 | Fox, K.M, Karplus, P.A. | | 登録日 | 1994-08-25 | | 公開日 | 1994-11-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Old yellow enzyme at 2 A resolution: overall structure, ligand binding, and comparison with related flavoproteins.
Structure, 2, 1994
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6D80
 | | Cryo-EM structure of the mitochondrial calcium uniporter from N. fischeri bound to saposin | | 分子名称: | CALCIUM ION, Mitochondrial calcium uniporter, Saposin A | | 著者 | Nguyen, N.X, Armache, J.-P, Cheng, Y, Bai, X.C. | | 登録日 | 2018-04-25 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5 Å) | | 主引用文献 | Cryo-EM structure of a fungal mitochondrial calcium uniporter.
Nature, 559, 2018
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3EIF
 | | 1.9 angstrom crystal structure of the active form of the C5a peptidase from Streptococcus pyogenes (ScpA) | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, C5a peptidase, CALCIUM ION, ... | | 著者 | Cooney, J.C, Kagawa, T.F, O'Connell, M.R, Paoli, M, Mouat, P, O'Toole, P.W. | | 登録日 | 2008-09-15 | | 公開日 | 2009-02-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Model for Substrate Interactions in C5a Peptidase from Streptococcus pyogenes: A 1.9 A Crystal Structure of the Active Form of ScpA
J.Mol.Biol., 386, 2009
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5E5Q
 | | Racemic snakin-1 in P21/c | | 分子名称: | Snakin-1 | | 著者 | Yeung, H, Squire, C.J, Yosaatmadja, Y, Panjikar, S, Baker, E.N, Harris, P.W.R, Brimble, M.A. | | 登録日 | 2015-10-09 | | 公開日 | 2016-05-18 | | 最終更新日 | 2016-07-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily.
Angew.Chem.Int.Ed.Engl., 55, 2016
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2IU7
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7W6O
 | | Crystal structure of a PSH1 in complex with J1K | | 分子名称: | 4-(2-hydroxyethylcarbamoyl)benzoic acid, PSH1 | | 著者 | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | 登録日 | 2021-12-02 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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7T3S
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7W6Q
 | | Crystal structure of a PSH1 in complex with ligand J1K | | 分子名称: | 4-(2-hydroxyethylcarbamoyl)benzoic acid, PSH1 | | 著者 | Gao, J, Lara, P, Li, Z.S, Han, X, Wei, R, Liu, W.D. | | 登録日 | 2021-12-02 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
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6DAW
 | | X-ray crystal structure of NapI L-arginine desaturase bound to Fe(II), L-arginine, and acetate | | 分子名称: | ACETATE ION, ARGININE, FE (II) ION, ... | | 著者 | Mitchell, A.J, Dunham, N.P, Boal, A.K. | | 登録日 | 2018-05-02 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of alpha-Heteroatom Assistance.
J. Am. Chem. Soc., 140, 2018
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1SVX
 | | Crystal structure of a designed selected Ankyrin Repeat protein in complex with the Maltose Binding Protein | | 分子名称: | Ankyrin Repeat Protein off7, Maltose-binding periplasmic protein | | 著者 | Binz, H.K, Amstutz, P, Kohl, A, Stumpp, M.T, Briand, C, Forrer, P, Gruetter, M.G, Plueckthun, A. | | 登録日 | 2004-03-30 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | High-affinity binders selected from designed ankyrin repeat protein libraries
NAT.BIOTECHNOL., 22, 2004
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7T0L
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1T8D
 | | Structure of the C-type lectin domain of CD23 | | 分子名称: | Low affinity immunoglobulin epsilon Fc receptor | | 著者 | Hibbert, R.G, Teriete, P, Grundy, G.J, Sutton, B.J, Gould, H.J, McDonnell, J.M. | | 登録日 | 2004-05-12 | | 公開日 | 2005-07-26 | | 最終更新日 | 2021-10-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of human CD23 and its interactions with IgE and CD21
J.Exp.Med., 202, 2005
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6SWX
 | | Leishmania major methionyl-tRNA synthetase in complex with an allosteric inhibitor | | 分子名称: | METHIONINE, Putative methionyl-tRNA synthetase, methyl 2-[[6-[[3,4-bis(fluoranyl)phenyl]amino]-1-methyl-pyrazolo[3,4-d]pyrimidin-4-yl]amino]ethanoate | | 著者 | Robinson, D.A, Torrie, L.S, Shepherd, S.M, De Rycker, M, Thomas, M.G, Wyatt, P.G. | | 登録日 | 2019-09-24 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase.
Acs Infect Dis., 6, 2020
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2IW9
 | | STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR | | 分子名称: | CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, MAGNESIUM ION, ... | | 著者 | Pratt, D.J, Bentley, J, Jewsbury, P, Boyle, F.T, Endicott, J.A, Noble, M.E.M. | | 登録日 | 2006-06-27 | | 公開日 | 2006-09-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Dissecting the Determinants of Cyclin-Dependent Kinase 2 and Cyclin-Dependent Kinase 4 Inhibitor Selectivity.
J.Med.Chem., 49, 2006
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2IW8
 | | STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A F82H-L83V-H84D MUTANT WITH AN O6-CYCLOHEXYLMETHYLGUANINE INHIBITOR | | 分子名称: | CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, MONOTHIOGLYCEROL, ... | | 著者 | Pratt, D.J, Bentley, J, Jewsbury, P, Boyle, F.T, Endicott, J.A, Noble, M.E.M. | | 登録日 | 2006-06-27 | | 公開日 | 2006-09-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Dissecting the Determinants of Cyclin-Dependent Kinase 2 and Cyclin-Dependent Kinase 4 Inhibitor Selectivity.
J.Med.Chem., 49, 2006
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2IVG
 | | SITE DIRECTED MUTAGENESIS OF KEY RESIDUES INVOLVED IN THE CATALYTIC MECHANISM OF CYANASE | | 分子名称: | AZIDE ION, CHLORIDE ION, CYANATE LYASE, ... | | 著者 | Guilloton, M, Walsh, M.A, Joachimiak, A, Anderson, P.M. | | 登録日 | 2006-06-13 | | 公開日 | 2008-10-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | A Twin Set of Low Pka Arginines Ensures the Concerted Acid Base Catalytic Mechanism of Cyanase
To be Published
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3N7B
 | | SgrAI bound to secondary site DNA and Ca(II) | | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*AP*CP*CP*GP*GP*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*CP*CP*CP*CP*CP*GP*GP*TP*GP*GP*AP*CP*T)-3'), ... | | 著者 | Horton, N.C, Little, E.J, Dunten, P.W. | | 登録日 | 2010-05-26 | | 公開日 | 2010-11-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA.
Acta Crystallogr.,Sect.D, 67, 2011
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5ZQ4
 | | PDE-Ubi-ADPr | | 分子名称: | ADENOSINE MONOPHOSPHATE, SidE, ubiquitin | | 著者 | Wang, Y, Gao, A, Gao, P. | | 登録日 | 2018-04-17 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.217 Å) | | 主引用文献 | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
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5AHO
 | | Crystal structure of human 5' exonuclease Apollo | | 分子名称: | 1,2-ETHANEDIOL, 5' EXONUCLEASE APOLLO, L(+)-TARTARIC ACID, ... | | 著者 | Allerston, C.K, Vollmar, M, Krojer, T, Pike, A.C.W, Newman, J.A, Carpenter, E, Quigley, A, Mahajan, P, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Gileadi, O. | | 登録日 | 2015-02-06 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | The Structures of the Snm1A and Snm1B/Apollo Nuclease Domains Reveal a Potential Basis for Their Distinct DNA Processing Activities.
Nucleic Acids Res., 43, 2015
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6IY5
 | | NMR solution structures of 5'-ATTCTATTCT-3 | | 分子名称: | DNA (5'-D(*AP*TP*TP*CP*TP*AP*TP*TP*CP*T)-3'), SODIUM ION | | 著者 | Lam, S.L, Guo, P. | | 登録日 | 2018-12-13 | | 公開日 | 2020-06-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Minidumbbell structures formed by ATTCT pentanucleotide repeats in spinocerebellar ataxia type 10.
Nucleic Acids Res., 48, 2020
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1JJT
 | | IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH A BIARYL SUCCINIC ACID INHIBITOR (1) | | 分子名称: | 2,3-BIS-BENZO[1,3]DIOXOL-5-YLMETHYL-SUCCINIC ACID, ACETATE ION, IMP-1 METALLO BETA-LACTAMASE, ... | | 著者 | Fitzgerald, P.M.D, Sharma, N. | | 登録日 | 2001-07-09 | | 公開日 | 2001-07-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase.
J.Biol.Chem., 276, 2001
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1TC8
 | | Crystal structure of Krait-venom phospholipase A2 in a complex with a natural fatty acid tridecanoic acid | | 分子名称: | N-TRIDECANOIC ACID, SODIUM ION, phospholipase A2 isoform 1 | | 著者 | Singh, G, Jasti, J, Saravanan, K, Sharma, S, Kaur, P, Srinivasan, A, Singh, T.P. | | 登録日 | 2004-05-21 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the complex formed between a group I phospholipase A2 and a naturally occurring fatty acid at 2.7 A resolution
PROTEIN SCI., 14, 2005
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6J9Q
 | | Crystal structure of Trypanosoma brucei gambiense glycerol kinase complex with AMP-PNP. | | 分子名称: | GLYCEROL, Glycerol kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Balogun, E.O, Chishima, T, Ichinose, M, Inaoka, D.K, Kido, Y, Ibrahim, B, de Koning, H, McKerrow, J.H, Watanabe, Y, Nozaki, T, Michels, P.A.M, Harada, S, Kita, K, Shiba, T. | | 登録日 | 2019-01-24 | | 公開日 | 2020-01-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Reaction mechanism of the reverse reaction of African human trypanosomes glycerol kinase.
To Be Published
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