5JTK
 
 | |
8THR
 | | Structure of the human vesicular monoamine transporter 2 (VMAT2) bound to tetrabenazine in an occluded conformation | | 分子名称: | (3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one, fluorescent protein mVenus,Synaptic vesicular amine transporter,GFP nano body,Synaptic vesicular amine transporter,Synaptic vesicular amine transporter | | 著者 | Dalton, M.P, Coleman, J.A. | | 登録日 | 2023-07-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Structural mechanisms for VMAT2 inhibition by tetrabenazine.
Elife, 12, 2024
|
|
4O5Q
 | | Crystal Structure of the Alkylhydroperoxide Reductase AhpF from Escherichia coli | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alkyl hydroperoxide reductase subunit F, CADMIUM ION, ... | | 著者 | Dip, P.V, Kamariah, N, Manimekalai, M.S.S, Balakrishna, A.M, Gruber, G. | | 登録日 | 2013-12-20 | | 公開日 | 2014-11-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure, mechanism and ensemble formation of the alkylhydroperoxide reductase subunits AhpC and AhpF from Escherichia coli
Acta Crystallogr.,Sect.D, 70, 2014
|
|
1Y6S
 | | HIV-1 DIS(Mal) duplex Ba-soaked | | 分子名称: | 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', BARIUM ION | | 著者 | Ennifar, E, Walter, P, Dumas, P. | | 登録日 | 2004-12-07 | | 公開日 | 2004-12-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A crystallographic study of the binding of 13 metal ions to two related RNA duplexes
Nucleic Acids Res., 31, 2003
|
|
3HKE
 | | Tubulin-T138067: RB3 stathmin-like domain complex | | 分子名称: | 2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)benzenesulfonamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M. | | 登録日 | 2009-05-23 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
5NF1
 | |
6IAT
 | | Icosahedrally averaged capsid of bacteriophage P68 | | 分子名称: | Arstotzka protein, Major head protein | | 著者 | Hrebik, D, Skubnik, K, Fuzik, T, Plevka, P. | | 登録日 | 2018-11-27 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure and genome ejection mechanism ofStaphylococcus aureusphage P68.
Sci Adv, 5, 2019
|
|
2VH4
 | | Structure of a loop C-sheet serpin polymer | | 分子名称: | TENGPIN | | 著者 | Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M. | | 登録日 | 2007-11-19 | | 公開日 | 2008-01-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A Structural Basis for Loop C-Sheet Polymerization in Serpins.
J.Mol.Biol., 376, 2008
|
|
5OQJ
 | | STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH | | 分子名称: | DNA repair helicase RAD25, DNA repair helicase RAD3, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Henning, U, Cramer, P. | | 登録日 | 2017-08-11 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structures of transcription pre-initiation complex with TFIIH and Mediator.
Nature, 551, 2017
|
|
5NGT
 | | Crystal structure of human MTH1 in complex with inhibitor 7-(furan-2-yl)-5-methyl-1,3-benzoxazol-2-amine | | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, 7-(furan-2-yl)-5-methyl-1,3-benzoxazol-2-amine, SULFATE ION | | 著者 | Gustafsson, R, Rudling, A, Almlof, I, Homan, E, Scobie, M, Warpman Berglund, U, Helleday, T, Carlsson, J, Stenmark, P. | | 登録日 | 2017-03-20 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space.
J. Med. Chem., 60, 2017
|
|
5OPN
 | | Crystal structure of R39Q cN-II mutant | | 分子名称: | Cytosolic purine 5'-nucleotidase, GLYCEROL | | 著者 | Hnizda, A, Pachl, P, Rezacova, P. | | 登録日 | 2017-08-10 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
|
|
6JT7
 | | Crystal structure of 452-453_deletion mutant of FGAM Synthetase | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | | 著者 | Sharma, N, Ahalawat, N, Sandhu, P, Mondal, J, Anand, R. | | 登録日 | 2019-04-10 | | 公開日 | 2020-03-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation.
Sci Adv, 6, 2020
|
|
3BLW
 | | Yeast Isocitrate Dehydrogenase with Citrate and AMP Bound in the Regulatory Subunits | | 分子名称: | ADENOSINE MONOPHOSPHATE, CITRATE ANION, Isocitrate dehydrogenase [NAD] subunit 1, ... | | 著者 | Taylor, A.B, Hu, G, Hart, P.J, McAlister-Henn, L. | | 登録日 | 2007-12-11 | | 公開日 | 2008-02-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Allosteric Motions in Structures of Yeast NAD+-specific Isocitrate Dehydrogenase.
J.Biol.Chem., 283, 2008
|
|
1D5W
 | | PHOSPHORYLATED FIXJ RECEIVER DOMAIN | | 分子名称: | SULFATE ION, TRANSCRIPTIONAL REGULATORY PROTEIN FIXJ | | 著者 | Birck, C, Mourey, L, Gouet, P, Fabry, B, Schumacher, J, Rousseau, P, Kahn, D, Samama, J.P. | | 登録日 | 1999-10-12 | | 公開日 | 2000-10-11 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Conformational changes induced by phosphorylation of the FixJ receiver domain.
Structure Fold.Des., 7, 1999
|
|
5KUH
 | | GluK2EM with LY466195 | | 分子名称: | (3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid, Glutamate receptor ionotropic, kainate 2 | | 著者 | Meyerson, J.R, Chittori, S, Merk, A, Rao, P, Han, T.H, Serpe, M, Mayer, M.L, Subramaniam, S. | | 登録日 | 2016-07-13 | | 公開日 | 2016-09-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (11.6 Å) | | 主引用文献 | Structural basis of kainate subtype glutamate receptor desensitization.
Nature, 537, 2016
|
|
6M0C
 | |
5KWD
 | |
5NJ3
 | | Structure of an ABC transporter: complete structure | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ... | | 著者 | Taylor, N.M.I, Manolaridis, I, Jackson, S.M, Kowal, J, Stahlberg, H, Locher, K.P. | | 登録日 | 2017-03-28 | | 公開日 | 2017-06-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | Structure of the human multidrug transporter ABCG2.
Nature, 546, 2017
|
|
6HN5
 | | Leucine-zippered human insulin receptor ectodomain with single bound insulin - "upper" membrane-distal part | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ... | | 著者 | Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. | | 登録日 | 2018-09-14 | | 公開日 | 2018-11-21 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The signalling conformation of the insulin receptor ectodomain.
Nat Commun, 9, 2018
|
|
2XSH
 | | CRYSTAL STRUCTURE OF P4 VARIANT OF BIPHENYL DIOXYGENASE FROM BURKHOLDERIA XENOVORANS LB400 IN COMPLEX WITH 2,6 DI CHLOROBIPHENYL | | 分子名称: | 2,6-DICHLOROBIPHENYL, BIPHENYL DIOXYGENASE SUBUNIT ALPHA, BIPHENYL DIOXYGENASE SUBUNIT BETA, ... | | 著者 | Kumar, P, Bolin, J.T. | | 登録日 | 2010-09-29 | | 公開日 | 2010-11-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Structural Insight Into the Expanded Pcb-Degrading Abilities of a Biphenyl Dioxygenase Obtained by Directed Evolution.
J.Mol.Biol., 405, 2011
|
|
2ZJQ
 | | Interaction of L7 with L11 induced by Microccocin binding to the Deinococcus radiodurans 50S subunit | | 分子名称: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. | | 登録日 | 2008-03-08 | | 公開日 | 2008-06-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
|
|
2Y2Y
 | | Oxidised form of E. coli CsgC | | 分子名称: | ACETATE ION, CURLI PRODUCTION PROTEIN CSGC | | 著者 | Taylor, J.D, Salgado, P.S, Constable, S.C, Cota, E, Mathews, S.J. | | 登録日 | 2010-12-16 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Atomic Resolution Insights Into Curli Fiber Biogenesis.
Structure, 19, 2011
|
|
5TL4
 | | Crystal structure of Sphingomonas paucimobilis aryl O-demethylase LigM | | 分子名称: | AMMONIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Kohler, A.C, Adams, P.D, Simmons, B.A, Sale, K.L. | | 登録日 | 2016-10-10 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | | 主引用文献 | Structure of aryl O-demethylase offers molecular insight into a catalytic tyrosine-dependent mechanism.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4MPK
 | | Crystal structure of the complex of buffalo signaling protein SPB-40 with N-acetylglucosamine at 2.65 A resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1, GLYCEROL | | 著者 | Yamini, S, Chaudhary, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2013-09-13 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal structure of the complex of buffalo signaling protein SPB-40 with N-acetylglucosamine at 2.65 A resolution
To be Published
|
|
3HMF
 | | Crystal Structure of the second Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Protein polybromo-1, ... | | 著者 | Filippakopoulos, P, Picaud, S, Keates, T, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2009-05-29 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
|
|
