6QB7
 
 | | Structure of the H1 domain of human KCTD16 | | 分子名称: | BTB/POZ domain-containing protein KCTD16, PHOSPHATE ION | | 著者 | Pinkas, D.M, Bufton, J.C, Williams, E.P, Strain-Damerell, C, Kupinska, K, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N, Structural Genomics Consortium (SGC) | | 登録日 | 2018-12-20 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Structure of the H1 domain of human KCTD16
To be published
|
|
7G8L
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1251207602 | | 分子名称: | 1-(5-methyl-1,3,4-thiadiazol-2-yl)piperidine, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
7G8N
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1262549981 | | 分子名称: | 1-anilinocyclopropane-1-carboxylic acid, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
7G8T
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1273312142 | | 分子名称: | 2-ethoxy-3-fluoro-N,N-dimethylbenzamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.385 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
7G8O
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1267800292 | | 分子名称: | DIMETHYL SULFOXIDE, FORMIC ACID, N-methyl-1H-indole-7-carboxamide, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.579 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
7G8W
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1416193393 | | 分子名称: | 4-(5-methyl-1H-pyrazol-4-yl)piperidine, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.939 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
7G92
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1545313172 | | 分子名称: | (2~{S})-~{N}-(4-aminocarbonylphenyl)oxolane-2-carboxamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.872 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
7G8Z
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1493056027 | | 分子名称: | 1-[(2R)-1-(methanesulfonyl)pyrrolidin-2-yl]methanamine, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.509 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
7G95
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z165170770 | | 分子名称: | DIMETHYL SULFOXIDE, FORMIC ACID, N-methyl-4-sulfamoylbenzamide, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.551 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
7G8Q
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1269220427 | | 分子名称: | 8-(methanesulfonyl)quinoline, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.561 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
6YCE
 | | Structure the bromelain protease from Ananas comosus with a thiomethylated active cysteine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FBSB, ISOPROPYL ALCOHOL, ... | | 著者 | Azarkan, M, Charlier, P, Herman, R, Delbrassine, F, Sauvage, E, M Rabet, N, Calvo Esposito, R, Kerff, F. | | 登録日 | 2020-03-18 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of the free and inhibitors-bound forms of bromelain and ananain from Ananas comosus stem and in vitro study of their cytotoxicity.
Sci Rep, 10, 2020
|
|
1HZG
 | | CRYSTAL STRUCTURE OF THE INACTIVE C866S MUTANT OF THE CATALYTIC DOMAIN OF E. COLI CYTOTOXIC NECROTIZING FACTOR 1 | | 分子名称: | CYTOTOXIC NECROTIZING FACTOR 1, PHOSPHATE ION | | 著者 | Buetow, L, Flatau, G, Chiu, K, Boquet, P, Ghosh, P. | | 登録日 | 2001-01-24 | | 公開日 | 2001-07-04 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structure of the Rho-activating domain of Escherichia coli cytotoxic necrotizing factor 1.
Nat.Struct.Biol., 8, 2001
|
|
7G8M
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1255459547 | | 分子名称: | DIMETHYL SULFOXIDE, FORMIC ACID, N-(1H-indol-7-yl)acetamide, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.029 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
7G8V
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z133716556 | | 分子名称: | DIMETHYL SULFOXIDE, FORMIC ACID, N-[(4R)-3,4-dihydro-2H-1-benzopyran-4-yl]methanesulfonamide, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.451 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
1ONF
 | | Crystal structure of Plasmodium falciparum Glutathione reductase | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Glutathione reductase | | 著者 | Sarma, G.N, Savvides, S.N, Becker, K, Schirmer, M, Schirmer, R.H, Karplus, P.A. | | 登録日 | 2003-02-27 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Glutathione reductase of the malarial parasite Plasmodium falciparum: Crystal structure and inhibitor development
J.Mol.Biol., 328, 2003
|
|
7G9C
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102141-001 | | 分子名称: | DIMETHYL SULFOXIDE, FORMIC ACID, N-[2-(methanesulfonyl)phenyl]acetamide, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.686 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
7G9D
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102179-001 | | 分子名称: | DIMETHYL SULFOXIDE, FORMIC ACID, N-[3-(2-oxopyrrolidin-1-yl)phenyl]acetamide, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.659 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
1HZS
 | | Crystal structure of a peptide nucleic acid duplex (BT-PNA) containing a bicyclic analogue of thymine | | 分子名称: | PEPTIDE NUCLEIC ACID | | 著者 | Eldrup, A.B, Nielsen, B.B, Haaima, G, Rasmussen, H, Kastrup, J.S, Christensen, C, Nielsen, P.E. | | 登録日 | 2001-01-26 | | 公開日 | 2001-07-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | 1,8-Naphthyridin-2(1H)-ones. Novel Bicyclic and Tricyclic Analogues of Thymine in Peptide Nucleic Acids (PNAs)
Eur.J.Org.Chem., 9, 2001
|
|
7G9G
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102236-001 | | 分子名称: | DIMETHYL SULFOXIDE, FORMIC ACID, N-(2-methoxyphenyl)acetamide, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.079 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
1VTD
 | | UNUSUAL HELICAL PACKING IN CRYSTALS OF DNA BEARING A MUTATION HOT SPOT | | 分子名称: | DNA (5'-D(*AP*CP*CP*GP*GP*CP*GP*CP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*GP*GP*CP*GP*CP*CP*GP*GP*T)-3') | | 著者 | Timsit, Y, Westhof, E, Fuchs, R.P.P, Moras, D. | | 登録日 | 1996-12-12 | | 公開日 | 2011-07-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Unusual helical packing in crystals of DNA bearing a mutation hot spot.
Nature, 341, 1989
|
|
5ZHL
 | | Crystal structure of TrmD from Mycobacterium tuberculosis in complex with active-site inhibitor | | 分子名称: | N-({4-[(octylamino)methyl]phenyl}methyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide, tRNA (guanine-N(1)-)-methyltransferase | | 著者 | Zhong, W, Pasunooti, K.K, Balamkundu, S, Wong, Y.W, Nah, Q, Liu, C.F, Lescar, J, Dedon, P.C. | | 登録日 | 2018-03-13 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
J.Med.Chem., 62, 2019
|
|
7SIC
 | | Human ATM Dimer | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine-protein kinase ATM | | 著者 | Warren, C, Pavletich, N.P. | | 登録日 | 2021-10-13 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | | 主引用文献 | Structure of the human ATM kinase and mechanism of Nbs1 binding.
Elife, 11, 2022
|
|
1ADV
 | | EARLY E2A DNA-BINDING PROTEIN | | 分子名称: | ADENOVIRUS SINGLE-STRANDED DNA-BINDING PROTEIN, ZINC ION | | 著者 | Kanellopoulos, P.N, Tsernoglou, D, Van Der Vliet, P.C, Tucker, P.A. | | 登録日 | 1995-05-12 | | 公開日 | 1996-06-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Alternative arrangements of the protein chain are possible for the adenovirus single-stranded DNA binding protein.
J.Mol.Biol., 257, 1996
|
|
7G82
 | | ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1079512010 | | 分子名称: | 6-methyl-2-[(3-methyl-1,2-oxazol-5-yl)methyl]pyridazin-3(2H)-one, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-06-22 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.409 Å) | | 主引用文献 | ARHGEF2 PanDDA analysis group deposition
To Be Published
|
|
4MOT
 | |
