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PDB: 46226 件

1IH6
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Multi-Conformation Crystal Structure of GGBr5CGCC
分子名称: 5'-D(*GP*GP*(CBR)P*GP*CP*C)-3'
著者Vargason, J.M, Henderson, K, Ho, P.S.
登録日2001-04-18
公開日2001-06-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A crystallographic map of the transition from B-DNA to A-DNA.
Proc.Natl.Acad.Sci.USA, 98, 2001
1F7Y
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THE CRYSTAL STRUCTURE OF TWO UUCG LOOPS HIGHLIGHTS THE ROLE PLAYED BY 2'-HYDROXYL GROUPS IN ITS UNUSUAL STABILITY
分子名称: 16S RIBOSOMAL RNA FRAGMENT, 30S RIBOSOMAL PROTEIN S15, MAGNESIUM ION, ...
著者Ennifar, E, Nikouline, A, Serganov, A, Tishchenko, S, Nevskaya, N, Garber, M, Ehresmann, B, Ehresmann, C, Nikonov, S, Dumas, P.
登録日2000-06-28
公開日2000-11-22
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of UUCG tetraloop.
J.Mol.Biol., 304, 2000
4MDG
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Closo Carborane Carbonic Anhydrase Inhibitor
分子名称: 1-(sulfamoylamino)methyl-1,2-dicarba-closo-dodecaborane, Carbonic anhydrase 2, ZINC ION
著者Brynda, J, Mader, P, Rezacova, P.
登録日2013-08-22
公開日2014-01-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Carborane-based carbonic anhydrase inhibitors.
Angew.Chem.Int.Ed.Engl., 52, 2013
4CFY
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SAVINASE CRYSTAL STRUCTURES FOR COMBINED SINGLE CRYSTAL DIFFRACTION AND POWDER DIFFRACTION ANALYSIS
分子名称: CALCIUM ION, SODIUM ION, SUBTILISIN SAVINASE
著者Frankaer, C.G, Moroz, O.V, Turkenburg, J.P, Aspmo, S.I, Thymark, M, Friis, E.P, Stahla, K, Nielsen, J.E, Wilson, K.S, Harris, P.
登録日2013-11-19
公開日2014-04-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Analysis of an Industrial Production Suspension of Bacillus Lentus Subtilisin Crystals by Powder Diffraction: A Powerful Quality-Control Tool.
Acta Crystallogr.,Sect.D, 70, 2014
2A2Q
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Complex of Active-site Inhibited Human Coagulation Factor VIIa with Human Soluble Tissue Factor in the Presence of Ca2+, Mg2+, Na+, and Zn2+
分子名称: CALCIUM ION, CHLORIDE ION, Coagulation factor VII, ...
著者Bajaj, S.P, Bajaj, M, Schmidt, A.E, Padmanabhan, K.
登録日2005-06-22
公開日2006-07-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa.
J.Biol.Chem., 281, 2006
2JAK
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Human PP2A regulatory subunit B56g
分子名称: SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM
著者Magnusdottir, A, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kotenyova, T, Lundgren, S, Moche, M, Nilsson, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Upsten, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Nordlund, P.
登録日2006-11-29
公開日2006-12-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Structure of the Pp2A Regulatory Subunit B56 Gamma: The Remaining Piece of the Pp2A Jigsaw Puzzle.
Proteins, 74, 2009
6MGN
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mouse Id1 (51-104) - human hE47 (348-399) complex
分子名称: DNA-binding protein inhibitor ID-1, Transcription factor E2-alpha
著者Benezra, R, Pavletich, N.P, Gall, A.-L, Goldgur, Y.
登録日2018-09-14
公開日2019-09-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Cell Rep, 29, 2019
1QWM
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Structure of Helicobacter pylori catalase with formic acid bound
分子名称: AZIDE ION, FORMIC ACID, KatA catalase, ...
著者Loewen, P.C, Carpena, X, Perez-Luque, R, Rovira, C, Haas, R, Odenbreit, S, Nicholls, P, Fita, I.
登録日2003-09-02
公開日2004-03-30
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of Helicobacter pylori Catalase, with and without Formic Acid Bound, at 1.6 A Resolution
Biochemistry, 43, 2004
3LGP
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Crystal structure of catalytic domain of tace with benzimidazolyl-thienyl-tartrate based inhibitor
分子名称: (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-{[2-(trifluoromethyl)-1H-benzimidazol-1-yl]methyl}thiophen-2-yl)methyl]butanamide, Disintegrin and metalloproteinase domain-containing protein 17, ZINC ION
著者Orth, P.
登録日2010-01-21
公開日2010-07-28
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and activity relationships of tartrate-based TACE inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
1QXR
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Crystal structure of phosphoglucose isomerase from Pyrococcus furiosus in complex with 5-phosphoarabinonate
分子名称: 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase, NICKEL (II) ION
著者Swan, M.K, Solomons, J.T.G, Beeson, C.C, Hansen, P, Schonheit, P, Davies, C.
登録日2003-09-08
公開日2003-12-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus
J.Biol.Chem., 278, 2003
5TQ5
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BU of 5tq5 by Molmil
Design and Synthesis of a pan-JAK Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin
分子名称: 6-(2-ethyl-4-hydroxyphenyl)-N-(6-methylpyridin-3-yl)-1H-indazole-3-carboxamide, Tyrosine-protein kinase JAK2
著者Chrencik, J, Jones, P.
登録日2016-10-23
公開日2017-01-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin.
J. Med. Chem., 60, 2017
3PP4
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BU of 3pp4 by Molmil
Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for the type I / type II distinction of anti- CD20 antibodies
分子名称: B-lymphocyte antigen CD20, CHLORIDE ION, GA101 Fab heavy chain, ...
著者Hopfner, K.-P, Lammens, A.
登録日2010-11-24
公開日2011-04-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies.
Blood, 118, 2011
1QY7
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The structure of the PII protein from the cyanobacteria Synechococcus sp. PCC 7942
分子名称: NICKEL (II) ION, Nitrogen regulatory protein P-II, SULFATE ION
著者Xu, Y, Carr, P.D, Clancy, P, Garcia-Dominguez, M, Forchhammer, K, Florencio, F, Tandeau de Marsac, N, Vasudevan, S.G, Ollis, D.L.
登録日2003-09-09
公開日2003-09-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structures of the PII proteins from the cyanobacteria Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803.
Acta Crystallogr.,Sect.D, 59, 2003
3LVE
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LEN Q38E MUTANT: A DOMAIN FLIP FROM A SINGLE AMINO ACID SUBSTITUTION
分子名称: LEN, ZINC ION
著者Schiffer, M, Pokkuluri, P.R.
登録日1998-05-12
公開日1999-05-18
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A domain flip as a result of a single amino-acid substitution.
Structure, 6, 1998
4KR6
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Crystal structure of a 4-thiouridine synthetase - RNA complex
分子名称: MERCURY (II) ION, Probable tRNA sulfurtransferase, RNA (39-MER)
著者Neumann, P, Ficner, R, Lakomek, K.
登録日2013-05-16
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of a 4-thiouridine synthetase-RNA complex reveals specificity of tRNA U8 modification.
Nucleic Acids Res., 42, 2014
6MGM
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BU of 6mgm by Molmil
Helix-Loop-helix motif of mouse DNA-binding protein inhibitor ID-1
分子名称: DNA-binding protein inhibitor ID-1
著者Benezra, R, Pavletich, N.P, Goldgur, Y, Gall, A.-L.
登録日2018-09-14
公開日2019-09-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.791 Å)
主引用文献A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Cell Rep, 29, 2019
2JHN
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3-methyladenine dna-glycosylase from Archaeoglobus fulgidus
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-METHYLADENINE DNA-GLYCOSYLASE, GLYCEROL, ...
著者Leiros, I, Nabong, M.P, Grosvik, K, Ringvoll, J, Haugland, G.T, Uldal, L, Reite, K, Olsbu, I.K, Knaevelsrud, I, Moe, E, Andersen, O.A, Birkeland, N.K, Ruoff, P, Klungland, A, Bjelland, S.
登録日2007-02-22
公開日2007-04-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Enzymatic Excision of N1-Methyladenine and N3-Methylcytosine from DNA
Embo J., 26, 2007
4BFQ
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Assembly of a triple pi-stack of ligands in the binding site of Aplysia californica acetylcholine binding protein (AChBP)
分子名称: 4,6-dimethyl-N'-(3-pyridin-2-ylisoquinolin-1-yl)pyrimidine-2-carboximidamide, GLYCEROL, SOLUBLE ACETYLCHOLINE RECEPTOR
著者Stornaiuolo, M, De Kloe, G.E, Rucktooa, P, Fish, A, van Elk, R, Edink, E.S, Bertrand, D, Smit, A.B, de Esch, I.J.P, Sixma, T.K.
登録日2013-03-21
公開日2013-05-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Assembly of a Pi-Pi Stack of Ligands in the Binding Site of an Acetylcholine Binding Protein
Nat.Commun., 4, 2013
3GZO
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HUMAN SOD1 G93A Variant
分子名称: COPPER (II) ION, GLYCEROL, MALONATE ION, ...
著者Galaleldeen, A, Taylor, A.B, Narayana, N, Whitson, L.J, Hart, P.J.
登録日2009-04-07
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A.
Arch.Biochem.Biophys., 492, 2009
3L6T
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Crystal Structure of an N-terminal Mutant of the Plasmid pCU1 TraI Relaxase Domain
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ...
著者Redinbo, M.R, Nash, R.P.
登録日2009-12-24
公開日2010-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献The mechanism and control of DNA transfer by the conjugative relaxase of resistance plasmid pCU1.
Nucleic Acids Res., 38, 2010
5W5F
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Cryo-EM structure of the T4 tail tube
分子名称: Tail tube protein gp19
著者Zheng, W, Wang, F, Taylor, N.M, Guerrero-Ferreira, R.C, Leiman, P.G, Egelman, E.H.
登録日2017-06-15
公開日2017-08-16
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Refined Cryo-EM Structure of the T4 Tail Tube: Exploring the Lowest Dose Limit.
Structure, 25, 2017
214D
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THE SOLUTION STRUCTURE OF A DNA DUPLEX CONTAINING A SINGLE 2'-O-METHYL-BETA-D-ARAT
分子名称: DNA (5'-D(*CP*GP*CP*AP*TP*AP*TP*AP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*AP*(T41)P*AP*TP*GP*CP*G)-3')
著者Gotfredsen, C.H, Spielmann, H.P, Wengel, J, Jacobsen, J.P.
登録日1995-07-07
公開日1995-10-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of a DNA duplex containing a single 2'-O-methyl-beta-D-araT: combined use of NMR, restrained molecular dynamics, and full relaxation matrix refinement.
Bioconjug.Chem., 7, 1996
4M1U
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The crystal structure of Stx2 and a disaccharide ligand
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-methyl beta-D-galactopyranoside, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Shiga toxin 2 A-subunit, ...
著者Yin, J, James, M.N.G, Jacobson, J.M, Kitov, P.I, Bundle, D.R, Mulvey, G, Armstrong, G.
登録日2013-08-04
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献The crystal structure of shiga toxin type 2 with bound disaccharide guides the design of a heterobifunctional toxin inhibitor.
J.Biol.Chem., 289, 2014
5WDO
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H-Ras bound to GMP-PNP at 277K
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Cofsky, J.C, Bandaru, P, Gee, C.L, Kuriyan, J.
登録日2017-07-05
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Deconstruction of the Ras switching cycle through saturation mutagenesis.
Elife, 6, 2017
1WRQ
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Crystal Structure of HutP-Antitermination complex
分子名称: 5'-R(*UP*UP*UP*AP*GP*UP*U)-3', HISTIDINE, Hut operon positive regulatory protein, ...
著者Kumarevel, T, Mizuno, H, Kumar, P.K.R.
登録日2004-10-25
公開日2005-08-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the HutP-antitermination complex
To be published

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