4J1R
| Crystal Structure of GSK3b in complex with inhibitor 15R | Descriptor: | (2R)-2-(1H-indol-3-ylmethyl)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, Glycogen synthase kinase-3 beta, PHOSPHATE ION, ... | Authors: | Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-02-01 | Release date: | 2013-03-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor To be Published
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6WWU
| KIF14[391-735] - ADP-AlFx in complex with a microtubule | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Benoit, M.P.M.H, Asenjo, A.B, Paydar, M, Dhakal, S, Kwok, B, Sosa, H. | Deposit date: | 2020-05-09 | Release date: | 2021-05-05 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14. Nat Commun, 12, 2021
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2W97
| Crystal Structure of eIF4E Bound to Glycerol and eIF4G1 peptide | Descriptor: | EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, GLYCEROL, ... | Authors: | Brown, C.J, Verma, C.S, Walkinshaw, M.D, Lane, D.P. | Deposit date: | 2009-01-22 | Release date: | 2010-03-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the cap-binding site. Cell Cycle, 8, 2009
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4DDZ
| Crystal structure of glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis | Descriptor: | GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE (GpgS), GLYCEROL | Authors: | Albesa-Jove, D, Urresti, S, Gest, P.M, van der Woerd, M, Jackson, M, Guerin, M.E. | Deposit date: | 2012-01-19 | Release date: | 2012-06-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria. J.Biol.Chem., 287, 2012
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7QSC
| GTPase IN COMPLEX WITH GDP.MGF3- | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 1, ... | Authors: | Baumann, P, Jin, Y. | Deposit date: | 2022-01-13 | Release date: | 2023-01-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | GTPase IN COMPLEX WITH GDP.MGF3- To Be Published
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7QTM
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6QU8
| Adenovirus Serotype 26 (Ad26) in complex with sialic acid, pH8.0 | Descriptor: | 1,2-ETHANEDIOL, Fiber, N-acetyl-alpha-neuraminic acid, ... | Authors: | Baker, A.T, Rizkallah, P.J, Parker, A.L, Mundy, R.M. | Deposit date: | 2019-02-26 | Release date: | 2019-09-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Human adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor. Sci Adv, 5, 2019
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1YOW
| human Steroidogenic Factor 1 LBD with bound Co-factor Peptide | Descriptor: | PHOSPHATIDYL ETHANOL, Steroidogenic factor 1, TIF2 peptide | Authors: | Krylova, I.N, Sablin, E.P, Xu, R.X, Waitt, G.M, Juzumiene, D, Williams, J.D, Ingraham, H.A, Willson, T.M, Williams, S.P, Montana, V, Madauss, K.P, Moore, J, Bynum, J.M, Lebedeva, L, MacKay, J.A, Suzawa, M, Guy, R.K, Thornton, J.W. | Deposit date: | 2005-01-28 | Release date: | 2005-05-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1 Cell(Cambridge,Mass.), 120, 2005
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4LSP
| Crystal structure of broadly and potently neutralizing antibody VRC-CH31 in complex with HIV-1 clade A/E gp120 93TH057 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | Authors: | Zhou, T, Moquin, S, Kwong, P.D. | Deposit date: | 2013-07-23 | Release date: | 2013-09-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies. Immunity, 39, 2013
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4LSR
| Crystal structure of broadly and potently neutralizing antibody VRC-CH31 in complex with HIV-1 clade A/E stran 93TH057 gp120 with LOOP D and Loop V5 from clade A strain KER_2018_11 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP120 WITH LOOP D AND V5 FROM STRAIN ker_2018_11, HEAVY CHAIN OF ANTIBODY VRC-CH31, ... | Authors: | Zhou, T, Moquin, S, Kwong, P.D. | Deposit date: | 2013-07-23 | Release date: | 2013-08-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies. Immunity, 39, 2013
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2N2O
| Structure of murine tumour necrosis factor alpha CDE RNA | Descriptor: | RNA (5'-R(P*GP*CP*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*UP*U)-3') | Authors: | Codutti, L, Leppek, K, Zalesak, J, Windeisen, V, Masiewicz, P, Stoecklin, G, Carlomagno, T. | Deposit date: | 2015-05-11 | Release date: | 2015-08-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A Distinct, Sequence-Induced Conformation Is Required for Recognition of the Constitutive Decay Element RNA by Roquin. Structure, 23, 2015
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1V4J
| Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima V73Y mutant | Descriptor: | SULFATE ION, octoprenyl-diphosphate synthase | Authors: | Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. | Deposit date: | 2003-11-14 | Release date: | 2004-03-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
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2IY3
| Structure of the E. Coli Signal Regognition Particle | Descriptor: | 4.5S RNA, SIGNAL SEQUENCE, Signal recognition particle protein,Signal recognition particle 54 kDa protein | Authors: | Schaffitzel, C, Oswald, M, Berger, I, Ishikawa, T, Abrahams, J.P, Koerten, H.K, Koning, R.I, Ban, N. | Deposit date: | 2006-07-12 | Release date: | 2006-11-02 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (16 Å) | Cite: | Structure of the E. Coli Signal Recognition Particle Bound to a Translating Ribosome Nature, 444, 2006
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4ILA
| The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium | Descriptor: | ACETATE ION, CESIUM ION, CHLORIDE ION, ... | Authors: | Sauguet, L, Corringer, P.J, Delarue, M. | Deposit date: | 2012-12-29 | Release date: | 2013-02-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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1VAM
| CONCANAVALIN A COMPLEX WITH 4'-NITROPHENYL-ALPHA-D-MANNOPYRANOSIDE | Descriptor: | 4-nitrophenyl alpha-D-mannopyranoside, CALCIUM ION, CONCANAVALIN A, ... | Authors: | Kanellopoulos, P.N, Tucker, P.A, Hamodrakas, S.J. | Deposit date: | 1996-01-08 | Release date: | 1997-01-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The crystal structure of the complexes of concanavalin A with 4'-nitrophenyl-alpha-D-mannopyranoside and 4'-nitrophenyl-alpha-D-glucopyranoside. J.Struct.Biol., 116, 1996
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7YEZ
| In situ structure of polymerase complex of mammalian reovirus in the reloaded state | Descriptor: | Lambda-2 protein, Mu-2 protein, RNA helicase, ... | Authors: | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | Deposit date: | 2022-07-06 | Release date: | 2023-03-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7QUM
| ATAD2 in complex with FragLite2 | Descriptor: | 1,2-ETHANEDIOL, 4-IODOPYRAZOLE, ATPase family AAA domain-containing protein 2, ... | Authors: | Turberville, S, Martin, M.P, Hope, I, Noble, M.E.M. | Deposit date: | 2022-01-18 | Release date: | 2023-03-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions. J.Med.Chem., 65, 2022
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7QCU
| Structure of the MUCIN-2 Cterminal domains partially deglycosylated. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-2, ... | Authors: | Gallego, P, Hansson, G.C. | Deposit date: | 2021-11-25 | Release date: | 2023-03-08 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins. Nat Commun, 14, 2023
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7QCN
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7XR9
| Crystal structure of DgpA with glucose | Descriptor: | DgpA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, beta-D-glucopyranose | Authors: | Ma, W, He, P. | Deposit date: | 2022-05-09 | Release date: | 2023-04-05 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C -glycoside cleaving enzyme and an O - to C -glycoside isomerase. Acta Pharm Sin B, 13, 2023
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1AUD
| U1A-UTRRNA, NMR, 31 STRUCTURES | Descriptor: | RNA 3UTR, U1A 102 | Authors: | Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. | Deposit date: | 1997-08-22 | Release date: | 1998-02-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural basis of the RNA-binding specificity of human U1A protein. EMBO J., 16, 1997
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7FSV
| SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1454310449 | Descriptor: | 1,2-ETHANEDIOL, ALANINE, D-GLUTAMIC ACID, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-01-24 | Release date: | 2023-02-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | SDCBP PanDDA analysis group deposition To Be Published
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7YF0
| In situ structure of polymerase complex of mammalian reovirus in the core | Descriptor: | Lambda-2 protein, Mu-2 protein, RNA helicase, ... | Authors: | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | Deposit date: | 2022-07-07 | Release date: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7QOG
| Portal protein assembly of the phicrAss001 virion with C12 symmetry imposed | Descriptor: | Cargo protein 1 gp45, Portal protein gp20, Ring protein 1 gp43, ... | Authors: | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | Deposit date: | 2021-12-24 | Release date: | 2023-03-29 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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7FT9
| SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z45636695 | Descriptor: | 1,2-ETHANEDIOL, 4-[(METHYLSULFONYL)AMINO]BENZOIC ACID, ALANINE, ... | Authors: | Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. | Deposit date: | 2023-01-24 | Release date: | 2023-02-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | SDCBP PanDDA analysis group deposition To Be Published
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