3MJH
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![BU of 3mjh by Molmil](/molmil-images/mine/3mjh) | Crystal Structure of Human Rab5A in complex with the C2H2 Zinc Finger of EEA1 | Descriptor: | Early endosome antigen 1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Mishra, A.K, Eathiraj, S, Lambright, D.G. | Deposit date: | 2010-04-12 | Release date: | 2010-05-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1). Proc.Natl.Acad.Sci.USA, 107, 2010
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6VKF
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![BU of 6vkf by Molmil](/molmil-images/mine/6vkf) | CCHFV GP38 (IbAr10200) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GP38 | Authors: | Mishra, A.K, McLellan, J.S. | Deposit date: | 2020-01-20 | Release date: | 2020-02-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.524 Å) | Cite: | Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38. J.Virol., 94, 2020
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5GO1
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![BU of 5go1 by Molmil](/molmil-images/mine/5go1) | Structural, Functional characterization and discovery of novel inhibitors of Leishmania amazonensis Nucleoside Diphosphatase Kinase (NDK) | Descriptor: | Nucleoside diphosphate kinase | Authors: | Mishra, A.K, Agnihotri, P, Singh, S.P, Pratap, J.V. | Deposit date: | 2016-07-26 | Release date: | 2017-07-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Discovery of novel inhibitors for Leishmania nucleoside diphosphatase kinase (NDK) based on its structural and functional characterization. J. Comput. Aided Mol. Des., 31, 2017
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8FWH
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![BU of 8fwh by Molmil](/molmil-images/mine/8fwh) | Crystal structure of bivalent antibody Fab fragment of Anti-human LAG3 (22D2) | Descriptor: | 1,2-ETHANEDIOL, Anti-human LAG3 (22D2) heavy chain, Anti-human LAG3 (22D2) light chain | Authors: | Mishra, A.K, Agnihotri, P, Mariuzza, R.A. | Deposit date: | 2023-01-22 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.833 Å) | Cite: | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker. Structure, 31, 2023
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2QKD
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![BU of 2qkd by Molmil](/molmil-images/mine/2qkd) | Crystal structure of tandem ZPR1 domains | Descriptor: | FORMIC ACID, ZINC ION, Zinc finger protein ZPR1 | Authors: | Mishra, A.K. | Deposit date: | 2007-07-10 | Release date: | 2007-08-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes. Proc.Natl.Acad.Sci.Usa, 104, 2007
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8SO3
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![BU of 8so3 by Molmil](/molmil-images/mine/8so3) | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, favezelimab Fab heavy chain, ... | Authors: | Mishra, A.K, Shahid, S, Karade, S.S, Mariuzza, R.A. | Deposit date: | 2023-04-28 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker. Structure, 31, 2023
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8SR0
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![BU of 8sr0 by Molmil](/molmil-images/mine/8sr0) | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 local refined | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, favezelimab Fab heavy chain, ... | Authors: | Mishra, A.K, Shahid, S, Karade, S.S, Mariuzza, R.A. | Deposit date: | 2023-05-05 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker. Structure, 31, 2023
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7L7R
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![BU of 7l7r by Molmil](/molmil-images/mine/7l7r) | |
7KX4
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![BU of 7kx4 by Molmil](/molmil-images/mine/7kx4) | Anti-CCHFV ADI-36121 Fab | Descriptor: | ADI-36121 Fab heavy chain, ADI-36121 Fab light chain | Authors: | Mishra, A.K, McLellan, J.S. | Deposit date: | 2020-12-03 | Release date: | 2021-12-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies. Science, 375, 2022
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4IRU
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![BU of 4iru by Molmil](/molmil-images/mine/4iru) | Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3 | Descriptor: | ACETATE ION, ALUMINUM FLUORIDE, GLYCEROL, ... | Authors: | Mishra, A.K, Delcampo, C.M, Collins, R.E, Roy, C.R, Lambright, D.G. | Deposit date: | 2013-01-15 | Release date: | 2013-07-10 | Last modified: | 2013-09-04 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism. J.Biol.Chem., 288, 2013
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6WKM
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![BU of 6wkm by Molmil](/molmil-images/mine/6wkm) | |
2HV8
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![BU of 2hv8 by Molmil](/molmil-images/mine/2hv8) | Crystal structure of GTP-bound Rab11 in complex with FIP3 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Eathiraj, S, Mishra, A, Prekeris, R, Lambright, D.G. | Deposit date: | 2006-07-27 | Release date: | 2006-11-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural Basis for Rab11-mediated Recruitment of FIP3 to Recycling Endosomes. J.Mol.Biol., 364, 2006
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8VVL
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![BU of 8vvl by Molmil](/molmil-images/mine/8vvl) | CCHFV GP38 bound to c13G8 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Hjorth, C.K, Mishra, A.K, McLellan, J.S. | Deposit date: | 2024-01-31 | Release date: | 2024-07-17 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38. Cell Rep, 43, 2024
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6WJU
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![BU of 6wju by Molmil](/molmil-images/mine/6wju) | |
6WK4
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![BU of 6wk4 by Molmil](/molmil-images/mine/6wk4) | |
6WKL
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![BU of 6wkl by Molmil](/molmil-images/mine/6wkl) | |
5X00
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![BU of 5x00 by Molmil](/molmil-images/mine/5x00) | |
6IEM
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![BU of 6iem by Molmil](/molmil-images/mine/6iem) | Argininosuccinate lyase from Mycobacterium tuberculosis | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15-PENTAOXAHEPTADECANE, Argininosuccinate lyase, ... | Authors: | Paul, A, Mishra, A, Surolia, A, Vijayan, M. | Deposit date: | 2018-09-14 | Release date: | 2019-02-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural studies on M. tuberculosis argininosuccinate lyase and its liganded complex: Insights into catalytic mechanism. IUBMB Life, 71, 2019
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6JCH
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![BU of 6jch by Molmil](/molmil-images/mine/6jch) | Crystal structure of SpaE basal pilin from Lactobacillus rhamnosus GG - Orthorhombic form | Descriptor: | Pilus assembly protein, SODIUM ION | Authors: | Megta, A.K, Mishra, A.K, Palva, A, von Ossowski, I, Krishnan, V. | Deposit date: | 2019-01-28 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.536 Å) | Cite: | Crystal structure of basal pilin SpaE reveals the molecular basis of its incorporation in the lactobacillar SpaFED pilus. J.Struct.Biol., 207, 2019
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6IEN
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![BU of 6ien by Molmil](/molmil-images/mine/6ien) | Substrate/product bound Argininosuccinate lyase from Mycobacterium tuberculosis | Descriptor: | 1,2-ETHANEDIOL, ARGININE, ARGININOSUCCINATE, ... | Authors: | Paul, A, Mishra, A, Surolia, A, Vijayan, M. | Deposit date: | 2018-09-14 | Release date: | 2019-02-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural studies on M. tuberculosis argininosuccinate lyase and its liganded complex: Insights into catalytic mechanism. IUBMB Life, 71, 2019
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6JBV
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![BU of 6jbv by Molmil](/molmil-images/mine/6jbv) | Crystal structure of SpaE basal pilin from Lactobacillus rhamnosus GG - Selenium derivative | Descriptor: | Pilus assembly protein, SODIUM ION | Authors: | Megta, A.K, Mishra, A.K, Palva, A, von Ossowski, I, Krishnan, V. | Deposit date: | 2019-01-26 | Release date: | 2019-06-26 | Last modified: | 2021-09-15 | Method: | X-RAY DIFFRACTION (1.712 Å) | Cite: | Crystal structure of basal pilin SpaE reveals the molecular basis of its incorporation in the lactobacillar SpaFED pilus. J.Struct.Biol., 207, 2019
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6JK7
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![BU of 6jk7 by Molmil](/molmil-images/mine/6jk7) | Crystal structure of SpaE basal pilin from Lactobacillus rhamnosus GG - Trigonal form | Descriptor: | Pilus assembly protein | Authors: | Megta, A.K, Mishra, A.K, Palva, A, von Ossowski, I, Krishnan, V. | Deposit date: | 2019-02-27 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.204 Å) | Cite: | Crystal structure of basal pilin SpaE reveals the molecular basis of its incorporation in the lactobacillar SpaFED pilus. J.Struct.Biol., 207, 2019
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8E1B
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![BU of 8e1b by Molmil](/molmil-images/mine/8e1b) | |
4LQ6
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![BU of 4lq6 by Molmil](/molmil-images/mine/4lq6) | Crystal structure of Rv3717 reveals a novel amidase from M. tuberculosis | Descriptor: | CHLORIDE ION, N-acetymuramyl-L-alanine amidase-related protein, PLATINUM (II) ION, ... | Authors: | Kumar, A, Kumar, S, Kumar, D, Mishra, A, Dewangan, R.P, Shrivastava, P, Ramachandran, S, Taneja, B. | Deposit date: | 2013-07-17 | Release date: | 2013-12-04 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | The structure of Rv3717 reveals a novel amidase from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 69, 2013
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4MXP
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![BU of 4mxp by Molmil](/molmil-images/mine/4mxp) | Structural Basis for PI(4)P-Specific Membrane Recruitment of the Legionella pneumophila Effector DrrA/SidM | Descriptor: | (2R)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, Defects in Rab1 recruitment protein A, SODIUM ION | Authors: | Del Campo, C.M, Mishra, A.K, Wang, Y.H, Roy, C.R, Janmey, P.A, Lambright, D.G. | Deposit date: | 2013-09-26 | Release date: | 2014-03-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural Basis for PI(4)P-Specific Membrane Recruitment of the Legionella pneumophila Effector DrrA/SidM. Structure, 22, 2014
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