4NIB
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4XST
| Structure of the endoglycosidase-H treated L1-CR domains of the human insulin receptor in complex with residues 697-719 of the human insulin receptor (A-isoform) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, SULFATE ION, ... | 著者 | Menting, J.G, Lawrence, C.F, Kong, G.K.-W, Lawrence, M.C. | 登録日 | 2015-01-22 | 公開日 | 2015-06-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors. Structure, 23, 2015
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6VER
| Human insulin analog: [GluB10,TyrB20]-DOI | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Menting, J.G, Chou, D.H.-C, Lawrence, M.C, Xiong, X. | 登録日 | 2020-01-02 | 公開日 | 2020-11-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.047 Å) | 主引用文献 | Mini-Ins: A minimal, bioactive insulin analog with alternative binding modes not published
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6VES
| Human insulin analog: [GluB10,HisA8,ArgA9]-DOI | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Menting, J.G, Chou, D.H.-C, Lawrence, M.C, Xiong, X. | 登録日 | 2020-01-02 | 公開日 | 2020-11-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Mini-Ins: A Minimal, Bioactive Insulin Analog with Alternative Binding Modes To Be Published
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5T7R
| A6-A11 trans-dicarba human insulin | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Menting, J.G, Lawrence, M.C, Robinson, A.J, Forbes, B.E. | 登録日 | 2016-09-05 | 公開日 | 2017-12-06 | 最終更新日 | 2019-06-19 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity. Sci Rep, 7, 2017
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6VET
| Human insulin analog: [GluB10,HisA8,ArgA9,TyrB20]-DOI | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Menting, J.G, Chou, D.H.-C, Lawrence, M.C, Xiong, X. | 登録日 | 2020-01-02 | 公開日 | 2020-06-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | A structurally minimized yet fully active insulin based on cone-snail venom insulin principles. Nat.Struct.Mol.Biol., 27, 2020
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6VEQ
| Con-Ins G1 in complex with the human insulin microreceptor in turn in complex with Fv 83-7 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Con-Ins G1 B chain, Con-Ins G1a A chain, ... | 著者 | Menting, J.G, Chou, D.H.-C, Lawrence, M.C, Xiong, X. | 登録日 | 2020-01-02 | 公開日 | 2020-06-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | A structurally minimized yet fully active insulin based on cone-snail venom insulin principles. Nat.Struct.Mol.Biol., 27, 2020
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7KD6
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4XSS
| Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ... | 著者 | Lawrence, C, Kong, G.K.-W, Menting, J.G, Lawrence, M.C. | 登録日 | 2015-01-22 | 公開日 | 2015-06-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors. Structure, 23, 2015
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6HN4
| Leucine-zippered human insulin receptor ectodomain with single bound insulin - "lower" membrane-proximal part | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor,Insulin receptor,General control protein GCN4 | 著者 | Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. | 登録日 | 2018-09-14 | 公開日 | 2018-11-21 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | The signalling conformation of the insulin receptor ectodomain. Nat Commun, 9, 2018
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6HN5
| Leucine-zippered human insulin receptor ectodomain with single bound insulin - "upper" membrane-distal part | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ... | 著者 | Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. | 登録日 | 2018-09-14 | 公開日 | 2018-11-21 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The signalling conformation of the insulin receptor ectodomain. Nat Commun, 9, 2018
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4OGA
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6VEP
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