8ADG
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![BU of 8adg by Molmil](/molmil-images/mine/8adg) | Cryo-EM structure of Darobactin 22 bound BAM complex | Descriptor: | Darobactin 22, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | Authors: | Yuan, B, Marlovits, T.C. | Deposit date: | 2022-07-08 | Release date: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Darobactins Exhibiting Superior Antibiotic Activity by Cryo-EM Structure Guided Biosynthetic Engineering. Angew.Chem.Int.Ed.Engl., 62, 2023
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8ADI
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![BU of 8adi by Molmil](/molmil-images/mine/8adi) | Cryo-EM structure of Darobactin 9 bound BAM complex | Descriptor: | Darobactin 9, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | Authors: | Yuan, B, Marlovits, T.C. | Deposit date: | 2022-07-08 | Release date: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Darobactins Exhibiting Superior Antibiotic Activity by Cryo-EM Structure Guided Biosynthetic Engineering. Angew.Chem.Int.Ed.Engl., 62, 2023
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8C4E
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![BU of 8c4e by Molmil](/molmil-images/mine/8c4e) | F-actin decorated by SipA426-685 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Yuan, B, Wald, J, Marlovits, T.C. | Deposit date: | 2023-01-03 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis for subversion of host cell actin cytoskeleton during Salmonella infection. Sci Adv, 9, 2023
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8CRB
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![BU of 8crb by Molmil](/molmil-images/mine/8crb) | Cryo-EM structure of PcrV/Fab(11-E5) | Descriptor: | Heavy chain, Light chain, Maltose/maltodextrin-binding periplasmic protein,Type III secretion protein PcrV | Authors: | Yuan, B, Simonis, A, Marlovits, T.C. | Deposit date: | 2023-03-08 | Release date: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa. Cell, 186, 2023
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8C4C
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![BU of 8c4c by Molmil](/molmil-images/mine/8c4c) | F-actin decorated by SipA497-669 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Yuan, B, Wald, J, Marlovits, T.C. | Deposit date: | 2023-01-03 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for subversion of host cell actin cytoskeleton during Salmonella infection. Sci Adv, 9, 2023
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2Y9J
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![BU of 2y9j by Molmil](/molmil-images/mine/2y9j) | |
2Y9K
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![BU of 2y9k by Molmil](/molmil-images/mine/2y9k) | |
8CR9
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![BU of 8cr9 by Molmil](/molmil-images/mine/8cr9) | Cryo-EM structure of PcrV/Fab(30-B8) | Descriptor: | Heavy chain, Maltose/maltodextrin-binding periplasmic protein,Type III secretion protein PcrV, light chain | Authors: | Yuan, B, Simonis, A, Marlovits, T.C. | Deposit date: | 2023-03-08 | Release date: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa. Cell, 186, 2023
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7PMW
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![BU of 7pmw by Molmil](/molmil-images/mine/7pmw) | HsPepT1 bound to Ala-Phe in the outward facing occluded conformation | Descriptor: | ALA-PHE, Solute carrier family 15 member 1 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-03 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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7PMX
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![BU of 7pmx by Molmil](/molmil-images/mine/7pmx) | HsPepT1 bound to Ala-Phe in the outward facing open conformation | Descriptor: | ALA-PHE, Solute carrier family 15 member 1 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-03 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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7PMY
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![BU of 7pmy by Molmil](/molmil-images/mine/7pmy) | HsPepT2 bound to Ala-Phe in the inward facing partially occluded conformation | Descriptor: | ALA-PHE, Solute carrier family 15 member 2 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-04 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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7PN1
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![BU of 7pn1 by Molmil](/molmil-images/mine/7pn1) | Apo HsPepT1 in the outward facing open conformation | Descriptor: | Solute carrier family 15 member 1 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-04 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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6ZNI
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![BU of 6zni by Molmil](/molmil-images/mine/6zni) | |
6ZNH
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![BU of 6znh by Molmil](/molmil-images/mine/6znh) | Structure of the Salmonella PrgI needle filament attached to the basal body | Descriptor: | PrgI | Authors: | Lunelli, M, Kotov, V, Wald, J, Kolbe, M, Marlovits, T.C. | Deposit date: | 2020-07-06 | Release date: | 2021-07-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Helical reconstruction of Salmonella and Shigella needle filaments attached to type 3 basal bodies. Biochem Biophys Rep, 27, 2021
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7NPT
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![BU of 7npt by Molmil](/molmil-images/mine/7npt) | Cytosolic bridge of an intact ESX-5 inner membrane complex | Descriptor: | ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5 | Authors: | Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C. | Deposit date: | 2021-02-28 | Release date: | 2021-05-26 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Structure and dynamics of a mycobacterial type VII secretion system. Nature, 593, 2021
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7NPS
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![BU of 7nps by Molmil](/molmil-images/mine/7nps) | Structure of the periplasmic assembly from the ESX-5 inner membrane complex, C1 model | Descriptor: | ESX-5 secretion system ATPase EccB5, Mycosin-5 | Authors: | Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C. | Deposit date: | 2021-02-28 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | Structure and dynamics of a mycobacterial type VII secretion system. Nature, 593, 2021
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7NP7
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![BU of 7np7 by Molmil](/molmil-images/mine/7np7) | Structure of an intact ESX-5 inner membrane complex, Composite C1 model | Descriptor: | ESX-5 secretion system ATPase EccB5, ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5, ... | Authors: | Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C. | Deposit date: | 2021-02-26 | Release date: | 2021-06-02 | Method: | ELECTRON MICROSCOPY (4.03 Å) | Cite: | Structure and dynamics of a mycobacterial type VII secretion system. Nature, 593, 2021
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7NPU
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![BU of 7npu by Molmil](/molmil-images/mine/7npu) | MycP5-free ESX-5 inner membrane complex, state I | Descriptor: | ESX-5 secretion system ATPase EccB5, ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5 | Authors: | Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C. | Deposit date: | 2021-02-28 | Release date: | 2021-06-02 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.48 Å) | Cite: | Structure and dynamics of a mycobacterial type VII secretion system. Nature, 593, 2021
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7NPR
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![BU of 7npr by Molmil](/molmil-images/mine/7npr) | Structure of an intact ESX-5 inner membrane complex, Composite C3 model | Descriptor: | ESX-5 secretion system ATPase EccB5, ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5, ... | Authors: | Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C. | Deposit date: | 2021-02-28 | Release date: | 2021-06-02 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Structure and dynamics of a mycobacterial type VII secretion system. Nature, 593, 2021
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7NPV
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![BU of 7npv by Molmil](/molmil-images/mine/7npv) | MycP5-free ESX-5 inner membrane complex, State II | Descriptor: | ESX-5 secretion system ATPase EccB5, ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5 | Authors: | Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C. | Deposit date: | 2021-02-28 | Release date: | 2021-06-02 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (6.66 Å) | Cite: | Structure and dynamics of a mycobacterial type VII secretion system. Nature, 593, 2021
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7OSL
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![BU of 7osl by Molmil](/molmil-images/mine/7osl) | |
7PBU
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![BU of 7pbu by Molmil](/molmil-images/mine/7pbu) | RuvAB branch migration motor complexed to the Holliday junction - RuvA-HJ core [t2 dataset] | Descriptor: | Holliday junction, Holliday junction ATP-dependent DNA helicase RuvA | Authors: | Goessweiner-Mohr, N, Fahrenkamp, D, Wald, J, Marlovits, T.C. | Deposit date: | 2021-08-02 | Release date: | 2022-09-14 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Mechanism of AAA+ ATPase-mediated RuvAB-Holliday junction branch migration. Nature, 609, 2022
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7PBL
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![BU of 7pbl by Molmil](/molmil-images/mine/7pbl) | RuvAB branch migration motor complexed to the Holliday junction - RuvB AAA+ state s1 [t2 dataset] | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Holliday junction ATP-dependent DNA helicase RuvA, Holliday junction ATP-dependent DNA helicase RuvB, ... | Authors: | Fahrenkamp, D, Goessweiner-Mohr, N, Wald, J, Marlovits, T.C. | Deposit date: | 2021-08-02 | Release date: | 2022-09-14 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanism of AAA+ ATPase-mediated RuvAB-Holliday junction branch migration. Nature, 609, 2022
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7PBO
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![BU of 7pbo by Molmil](/molmil-images/mine/7pbo) | RuvAB branch migration motor complexed to the Holliday junction - RuvB AAA+ state s4 [t2 dataset] | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Holliday junction ATP-dependent DNA helicase RuvA, Holliday junction ATP-dependent DNA helicase RuvB, ... | Authors: | Fahrenkamp, D, Goessweiner-Mohr, N, Wald, J, Marlovits, T.C. | Deposit date: | 2021-08-02 | Release date: | 2022-09-14 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Mechanism of AAA+ ATPase-mediated RuvAB-Holliday junction branch migration. Nature, 609, 2022
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7PBT
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![BU of 7pbt by Molmil](/molmil-images/mine/7pbt) | RuvAB branch migration motor complexed to the Holliday junction - RuvB AAA+ state s1 [t1 dataset] | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Holliday junction ATP-dependent DNA helicase RuvA, Holliday junction ATP-dependent DNA helicase RuvB, ... | Authors: | Wald, J, Fahrenkamp, D, Goessweiner-Mohr, N, Marlovits, T.C. | Deposit date: | 2021-08-02 | Release date: | 2022-09-14 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Mechanism of AAA+ ATPase-mediated RuvAB-Holliday junction branch migration. Nature, 609, 2022
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