4NCV
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![BU of 4ncv by Molmil](/molmil-images/mine/4ncv) | Foldon domain wild type N-conjugate | 分子名称: | Fibritin | 著者 | Graewert, M.A, Berthelmann, A, Lach, J, Groll, M, Eichler, J. | 登録日 | 2013-10-25 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Versatile C(3)-symmetric scaffolds and their use for covalent stabilization of the foldon trimer. Org.Biomol.Chem., 12, 2014
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4NQS
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![BU of 4nqs by Molmil](/molmil-images/mine/4nqs) | Knob-into-hole IgG Fc | 分子名称: | Ig gamma-1 chain C region, miniZ | 著者 | Eigenbrot, C, Ultsch, M. | 登録日 | 2013-11-25 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2-CH3 Hydrophobic Interaction. J.Mol.Biol., 426, 2014
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4NVG
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4NZC
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![BU of 4nzc by Molmil](/molmil-images/mine/4nzc) | Crystal structure of Chitinase D from Serratia proteamaculans at 1.45 Angstrom resolution | 分子名称: | ACETATE ION, GLYCEROL, Glycoside hydrolase family 18 | 著者 | Madhuprakash, J, Singh, A, Kumar, S, Sinha, M, Kaur, P, Sharma, S, Podile, A.R, Singh, T.P. | 登録日 | 2013-12-12 | 公開日 | 2014-01-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of chitinase D from Serratia proteamaculans reveals the structural basis of its dual action of hydrolysis and transglycosylation Int J Biochem Mol Biol, 4, 2013
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4NNQ
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![BU of 4nnq by Molmil](/molmil-images/mine/4nnq) | Crystal structure of LnmF protein from Streptomyces amphibiosporus | 分子名称: | Putative enoyl-CoA hydratase, SULFATE ION | 著者 | Michalska, K, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2013-11-18 | 公開日 | 2014-01-15 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 |
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4O0J
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![BU of 4o0j by Molmil](/molmil-images/mine/4o0j) | HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[4-(4-chlorophenyl)-6-(3,4-dimethylphenyl)-2,5-dimethylpyridin-3-yl]ethanoic acid | 分子名称: | (2S)-tert-butoxy[4-(4-chlorophenyl)-6-(3,4-dimethylphenyl)-2,5-dimethylpyridin-3-yl]ethanoic acid, Integrase, SULFATE ION | 著者 | Feng, L, Kvaratskhelia, M. | 登録日 | 2013-12-13 | 公開日 | 2014-07-02 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase. Plos Pathog., 10, 2014
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4QKS
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![BU of 4qks by Molmil](/molmil-images/mine/4qks) | Crystal Structure of 6xTrp/PV2: de novo designed beta-trefoil architecture with symmetric primary structure (L22W/L44W/L64W/L85W/L108W/L132W his Primitive Version 2) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DE NOVO PROTEIN 6XTRP/PV2, SULFATE ION | 著者 | Longo, L.M, Tenorio, C.A, Blaber, M. | 登録日 | 2014-06-09 | 公開日 | 2015-01-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A single aromatic core mutation converts a designed "primitive" protein from halophile to mesophile folding. Protein Sci., 24, 2015
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4QHT
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![BU of 4qht by Molmil](/molmil-images/mine/4qht) | Crystal structure of AAA+/ sigma 54 activator domain of the flagellar regulatory protein FlrC from Vibrio cholerae in ATP analog bound state | 分子名称: | 1,2-ETHANEDIOL, Flagellar regulatory protein C, MAGNESIUM ION, ... | 著者 | Dey, S, Biswas, M, Sen, U, Dasgupta, J. | 登録日 | 2014-05-29 | 公開日 | 2014-07-16 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.559 Å) | 主引用文献 | Unique ATPase site architecture triggers cis-mediated synchronized ATP binding in heptameric AAA+-ATPase domain of flagellar regulatory protein FlrC J.Biol.Chem., 290, 2015
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4QG4
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![BU of 4qg4 by Molmil](/molmil-images/mine/4qg4) | Crystal structure of the tetrameric GTP/dATP/ATP-bound SAMHD1 (H210A) mutant catalytic core | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | 登録日 | 2014-05-22 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates. J.Biol.Chem., 289, 2014
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4QOI
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![BU of 4qoi by Molmil](/molmil-images/mine/4qoi) | Crystal structure of FMN quinone reductase 2 in complex with melatonin at 1.55A | 分子名称: | FLAVIN MONONUCLEOTIDE, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | 著者 | Serriere, J, Boutin, J.A, Isabet, T, Antoine, M, Ferry, G. | 登録日 | 2014-06-20 | 公開日 | 2015-07-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of FMN quinone reductase 2 in complex with melatonin at 1.55A To be Published
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4QHH
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![BU of 4qhh by Molmil](/molmil-images/mine/4qhh) | Crystal structure of Methanocaldococcus jannaschii tetrameric selecase | 分子名称: | GLYCEROL, SODIUM ION, Uncharacterized protein MJ1213, ... | 著者 | Lopez-pelegrin, M, Cerda-costa, N, Cintas-pedrola, A, Herranz-trillo, F, Bernado, P, Peinado, J.R, Arolas, J.L, Gomis-ruth, F.X. | 登録日 | 2014-05-28 | 公開日 | 2014-07-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Multiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidase Angew.Chem.Int.Ed.Engl., 53, 2014
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4QPB
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![BU of 4qpb by Molmil](/molmil-images/mine/4qpb) | Catalytic domain of the antimicrobial peptidase lysostaphin from Staphylococcus simulans crystallized in the absence of phosphate | 分子名称: | 1,2-ETHANEDIOL, Lysostaphin, ZINC ION | 著者 | Sabala, I, Jagielska, E, Bardelang, P.T, Czapinska, H, Dahms, S.O, Sharpe, J.A, James, R, Than, M.E, Thomas, N.R, Bochtler, M. | 登録日 | 2014-06-22 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans. Febs J., 281, 2014
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4QI0
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![BU of 4qi0 by Molmil](/molmil-images/mine/4qi0) | X-ray structure of the ROQ domain from murine Roquin-1 | 分子名称: | 1,2-ETHANEDIOL, Roquin-1 | 著者 | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | 登録日 | 2014-05-30 | 公開日 | 2014-07-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation. Nat.Struct.Mol.Biol., 21, 2014
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4QMC
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![BU of 4qmc by Molmil](/molmil-images/mine/4qmc) | Crystal structure of complex formed between phospholipase A2 and Biotin-sulfoxide at 1.09 A Resolution | 分子名称: | ACETATE ION, BIOTIN-D-SULFOXIDE, GLYCEROL, ... | 著者 | Shukla, P.K, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2014-06-16 | 公開日 | 2014-07-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Crystal structure of complex formed between phospholipase A2 and Biotin-sulfoxide at 1.09 A Resolution To be published
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4QO7
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4QOG
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![BU of 4qog by Molmil](/molmil-images/mine/4qog) | Crystal structure of fad quinone reductase 2 in complex with melatonin at 1.4A | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | 著者 | Serriere, J, Boutin, J.A, Isabet, T, Antoine, M, Ferry, G. | 登録日 | 2014-06-20 | 公開日 | 2015-07-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of fad quinone reductase 2 in complex with melatonin at 1.4A To be Published
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4QOE
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![BU of 4qoe by Molmil](/molmil-images/mine/4qoe) | The value 'crystal structure of fad quinone reductase 2 at 1.45A | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | 著者 | Serriere, J, Boutin, J.A, Isabet, T, Antoine, M, Ferry, G. | 登録日 | 2014-06-20 | 公開日 | 2015-07-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The value 'crystal structure of fad quinone reductase 2 at 1.45A To be Published
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4QNS
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![BU of 4qns by Molmil](/molmil-images/mine/4qns) | Crystal structure of bromodomain from Plasmodium faciparum GCN5, PF3D7_0823300 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Histone acetyltransferase GCN5, ... | 著者 | Fonseca, M, Tallant, C, Knapp, S, Loppnau, P, von Delft, F, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Structural Genomics Consortium (SGC) | 登録日 | 2014-06-18 | 公開日 | 2014-07-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.497 Å) | 主引用文献 | Crystal structure of bromodomain from Plasmodium faciparum GCN5, PF3D7_0823300 TO BE PUBLISHED
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4QOF
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![BU of 4qof by Molmil](/molmil-images/mine/4qof) | Crystal structure of fmn quinone reductase 2 AT 1.55A | 分子名称: | FLAVIN MONONUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION | 著者 | Serriere, J, Boutin, J.A, Isabet, T, Antoine, M, Ferry, G. | 登録日 | 2014-06-20 | 公開日 | 2015-07-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of FMN quinone reductase 2 at 1.55A To be Published
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4QPT
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![BU of 4qpt by Molmil](/molmil-images/mine/4qpt) | Structural Investigation of hnRNP L | 分子名称: | Heterogenous nuclear ribonucleoprotein L, PHOSPHATE ION | 著者 | Blatter, M, Allain, F.H.-T. | 登録日 | 2014-06-25 | 公開日 | 2015-05-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.351 Å) | 主引用文献 | The Signature of the Five-Stranded vRRM Fold Defined by Functional, Structural and Computational Analysis of the hnRNP L Protein. J.Mol.Biol., 427, 2015
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4QQ5
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![BU of 4qq5 by Molmil](/molmil-images/mine/4qq5) | Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex With FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations | 分子名称: | Fibroblast growth factor receptor 4, N-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)propanamide | 著者 | Huang, Z, Mohammadi, M. | 登録日 | 2014-06-26 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | 主引用文献 | DFG-out Mode of Inhibition by an Irreversible Type-1 Inhibitor Capable of Overcoming Gate-Keeper Mutations in FGF Receptors. Acs Chem.Biol., 10, 2015
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2Z3A
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![BU of 2z3a by Molmil](/molmil-images/mine/2z3a) | Crystal Structure of Bacillus Subtilis CodW, a non-canonical HslV-like peptidase with an impaired catalytic apparatus | 分子名称: | ATP-dependent protease hslV | 著者 | Rho, S.H, Park, H.H, Kang, G.B, Lim, Y.J, Kang, M.S, Lim, B.K, Seong, I.S, Chung, C.H, Wang, J, Eom, S.H. | 登録日 | 2007-06-03 | 公開日 | 2008-03-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of Bacillus subtilis CodW, a noncanonical HslV-like peptidase with an impaired catalytic apparatus Proteins, 71, 2007
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4QPF
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![BU of 4qpf by Molmil](/molmil-images/mine/4qpf) | New lower bone affinity bisphosphonate drug design for effective use in diseases characterized by abnormal bone resorption | 分子名称: | Farnesyl pyrophosphate synthase, MAGNESIUM ION, [1-fluoro-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-diyl]bis(phosphonic acid) | 著者 | Ebetino, F.H, Lundy, M, Kwaasi, A.A, Dunford, J.E, Duan, Z, Triffitt, J, Mazur, A, Jeans, G, Barnett, B.L, Russell, R.G.G. | 登録日 | 2014-06-23 | 公開日 | 2015-06-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | New lower bone affinity bisphosphonate drug design for effective use in diseases characterized by abnormal bone resorption To be Published
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4N1L
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![BU of 4n1l by Molmil](/molmil-images/mine/4n1l) | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | 分子名称: | NACHT, LRR and PYD domains-containing protein 14 | 著者 | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | 登録日 | 2013-10-04 | 公開日 | 2014-07-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.986 Å) | 主引用文献 | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
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4MWF
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![BU of 4mwf by Molmil](/molmil-images/mine/4mwf) | Structure of Hepatitis C Virus Envelope Glycoprotein E2 core bound to broadly neutralizing antibody AR3C | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | 著者 | Kong, L, Wilson, I.A, Law, M. | 登録日 | 2013-09-24 | 公開日 | 2013-12-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.645 Å) | 主引用文献 | Hepatitis C virus e2 envelope glycoprotein core structure. Science, 342, 2013
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