4NC9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nc9 by Molmil](/molmil-images/mine/4nc9) | Crystal structure of phosphatidyl mannosyltransferase PimA | 分子名称: | GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase | 著者 | Giganti, D, Albesa-Jove, D, Bellinzoni, M, Guerin, M.E, Alzari, P.M. | 登録日 | 2013-10-24 | 公開日 | 2014-11-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.192 Å) | 主引用文献 | Secondary structure reshuffling modulates glycosyltransferase function at the membrane. Nat.Chem.Biol., 11, 2015
|
|
4NCY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ncy by Molmil](/molmil-images/mine/4ncy) | In situ trypsin crystallized on a MiTeGen micromesh with imidazole ligand | 分子名称: | 1,2-ETHANEDIOL, BENZAMIDINE, CALCIUM ION, ... | 著者 | Yin, X, Scalia, A, Leroy, L, Cuttitta, C.M, Polizzo, G.M, Ericson, D.L, Roessler, C.G, Campos, O, Agarwal, R, Allaire, M, Orville, A.M, Jackimowicz, R, Ma, M.Y, Sweet, R.M, Soares, A.S. | 登録日 | 2013-10-25 | 公開日 | 2014-04-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes. Acta Crystallogr.,Sect.D, 70, 2014
|
|
4NE7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ne7 by Molmil](/molmil-images/mine/4ne7) | Crystal Structure of engineered Kumamolisin-As from Alicyclobacillus sendaiensis, Northeast Structural Genomics Consortium (NESG) Target OR367 | 分子名称: | Kumamolisin-As, ZINC ION | 著者 | Guan, R, Pultz, I.S, Siegel, J.B, Seetharaman, J, Kornhaber, G, Maglaqui, M, Mao, L, Xiao, R, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-10-28 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.497 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target OR367 To be Published
|
|
4NP6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4np6 by Molmil](/molmil-images/mine/4np6) | Crystal Structure of Adenylate Kinase from Vibrio cholerae O1 biovar eltor | 分子名称: | Adenylate kinase | 著者 | Kim, Y, Zhou, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2013-11-20 | 公開日 | 2013-12-18 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | 主引用文献 | Crystal Structure of Adenylate Kinase from Vibrio cholerae O1 biovar eltor To be Published
|
|
4NPP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4npp by Molmil](/molmil-images/mine/4npp) | The GLIC-His10 wild-type structure in equilibrium between the open and locally-closed (LC) forms | 分子名称: | NICKEL (II) ION, Proton-gated ion channel | 著者 | Sauguet, L, Shahsavar, A, Poitevin, F, Huon, C, Menny, A, Nemecz, A, Haouz, A, Changeux, J.P, Corringer, P.J, Delarue, M. | 登録日 | 2013-11-22 | 公開日 | 2013-12-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4NNN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nnn by Molmil](/molmil-images/mine/4nnn) | yCP in complex with MG132 | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]-L-leucinamide, Probable proteasome subunit alpha type-7, ... | 著者 | Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M. | 登録日 | 2013-11-18 | 公開日 | 2014-02-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
4NQT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nqt by Molmil](/molmil-images/mine/4nqt) | |
4NTC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ntc by Molmil](/molmil-images/mine/4ntc) | Crystal structure of GliT | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GliT | 著者 | Scharf, D.H, Groll, M, Habel, A, Heinekamp, T, Hertweck, C, Brakhage, A.A, Huber, E.M. | 登録日 | 2013-12-02 | 公開日 | 2014-03-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Flavoenzyme-Catalyzed Formation of Disulfide Bonds in Natural Products Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
4NTE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nte by Molmil](/molmil-images/mine/4nte) | Crystal structure of DepH | 分子名称: | CHLORIDE ION, DepH, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Scharf, D.H, Groll, M, Habel, A, Heinekamp, T, Hertweck, C, Brakhage, A.A, Huber, E.M. | 登録日 | 2013-12-02 | 公開日 | 2014-03-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Flavoenzyme-Catalyzed Formation of Disulfide Bonds in Natural Products Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
3UK3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uk3 by Molmil](/molmil-images/mine/3uk3) | Crystal structure of ZNF217 bound to DNA | 分子名称: | 5'-D(*AP*AP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', CHLORIDE ION, ... | 著者 | Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P. | 登録日 | 2011-11-08 | 公開日 | 2012-12-05 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Rediscovering DNA recognition by classical Zinc Fingers. To be Published
|
|
8GNG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gng by Molmil](/molmil-images/mine/8gng) | Crystal structure of human adenosine A2A receptor in complex with istradefylline. | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 8-[(~{E})-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6-dione, Adenosine receptor A2a, ... | 著者 | Suzuki, M, Saito, J, Miyagi, H, Yasunaga, M. | 登録日 | 2022-08-23 | 公開日 | 2023-03-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A 2A Receptor Antagonist/Inverse Agonist. Mol.Pharmacol., 103, 2023
|
|
5FHC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fhc by Molmil](/molmil-images/mine/5fhc) | |
8GNE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gne by Molmil](/molmil-images/mine/8gne) | Crystal structure of human adenosine A2A receptor in complex with an insurmountable inverse agonist, KW-6356. | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Adenosine receptor A2a,Soluble cytochrome b562, ... | 著者 | Suzuki, M, Saito, J, Miyagi, H, Yasunaga, M. | 登録日 | 2022-08-23 | 公開日 | 2023-03-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A 2A Receptor Antagonist/Inverse Agonist. Mol.Pharmacol., 103, 2023
|
|
4NXT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nxt by Molmil](/molmil-images/mine/4nxt) | Crystal structure of the cytosolic domain of human MiD51 | 分子名称: | GLYCEROL, Mitochondrial dynamic protein MID51, SULFATE ION | 著者 | Richter, V, Ryan, M.T, Kvansakul, M. | 登録日 | 2013-12-09 | 公開日 | 2013-12-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission. J.Cell Biol., 204, 2014
|
|
1A3S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1a3s by Molmil](/molmil-images/mine/1a3s) | HUMAN UBC9 | 分子名称: | UBC9 | 著者 | Naismith, J.H, Giraud, M. | 登録日 | 1998-01-23 | 公開日 | 1998-05-27 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of ubiquitin-conjugating enzyme 9 displays significant differences with other ubiquitin-conjugating enzymes which may reflect its specificity for sumo rather than ubiquitin. Acta Crystallogr.,Sect.D, 54, 1998
|
|
4NCU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ncu by Molmil](/molmil-images/mine/4ncu) | |
4O3P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o3p by Molmil](/molmil-images/mine/4o3p) | Crystal structure of human polymerase eta inserting dctp opposite an 8-oxog containing dna template | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | 著者 | Patra, A, Egli, M. | 登録日 | 2013-12-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
|
|
4PWG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pwg by Molmil](/molmil-images/mine/4pwg) | Crystal structure of V30M mutant human transthyretin complexed with caffeic acid ethyl ester | 分子名称: | CALCIUM ION, Transthyretin, ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate | 著者 | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | 登録日 | 2014-03-20 | 公開日 | 2014-11-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | 主引用文献 | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin J.Med.Chem., 57, 2014
|
|
4Q1U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q1u by Molmil](/molmil-images/mine/4q1u) | Serum paraoxonase-1 by directed evolution with the K192Q mutation | 分子名称: | BROMIDE ION, CALCIUM ION, CHLORIDE ION, ... | 著者 | Ben-David, M, Sussman, J.L, Tawfik, D.S. | 登録日 | 2014-04-04 | 公開日 | 2015-02-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | 主引用文献 | Catalytic stimulation by restrained active-site floppiness-the case of high density lipoprotein-bound serum paraoxonase-1. J.Mol.Biol., 427, 2015
|
|
4PXO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pxo by Molmil](/molmil-images/mine/4pxo) | Crystal structure of Maleylacetoacetate isomerase from Methylobacteriu extorquens AM1 WITH BOUND MALONATE AND GSH (TARGET EFI-507068) | 分子名称: | 1,2-ETHANEDIOL, GLUTATHIONE, MALONIC ACID, ... | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Imker, H.J, Al Obaidi, N, Stead, M, Love, J, Gerlt, J.A, Armstrong, R.N, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2014-03-24 | 公開日 | 2014-04-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of glutathione s-transferase zeta from Methylobacterium extorquens (TARGET EFI-507068) To be Published
|
|
4Q4J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q4j by Molmil](/molmil-images/mine/4q4j) | Structure of crosslinked TM287/288_S498C_S520C mutant | 分子名称: | ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288 | 著者 | Hohl, M, Schoeppe, J, Gruetter, M.G, Seeger, M.A. | 登録日 | 2014-04-14 | 公開日 | 2014-07-16 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4Q6M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q6m by Molmil](/molmil-images/mine/4q6m) | Structural analysis of the apo-form of Helicobacter pylori Csd4, a D,L-carboxypeptidase | 分子名称: | CALCIUM ION, Conserved hypothetical secreted protein, GLYCEROL | 著者 | Kim, H.S, Kim, J, Im, H.N, An, D.R, Lee, M, Hesek, D, Mobashery, S, Kim, J.Y, Cho, K, Yoon, H.J, Han, B.W, Lee, B.I, Suh, S.W. | 登録日 | 2014-04-23 | 公開日 | 2014-11-05 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the recognition of muramyltripeptide by Helicobacter pylori Csd4, a D,L-carboxypeptidase controlling the helical cell shape Acta Crystallogr.,Sect.D, 70, 2014
|
|
4Q1H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q1h by Molmil](/molmil-images/mine/4q1h) | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Polyketide biosynthesis enoyl-CoA isomerase PksI, ... | 著者 | Nair, A.V, Race, P.R, Till, M. | 登録日 | 2014-04-03 | 公開日 | 2015-05-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-methyl branch incorporation. Sci Rep, 10, 2020
|
|
4Q7K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q7k by Molmil](/molmil-images/mine/4q7k) | |
4Q7L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q7l by Molmil](/molmil-images/mine/4q7l) | Structure of NBD288 of TM287/288 | 分子名称: | NICKEL (II) ION, Uncharacterized ABC transporter ATP-binding protein TM_0288 | 著者 | Bukowska, M.A, Hohl, M, Gruetter, M.G, Seeger, M.A. | 登録日 | 2014-04-25 | 公開日 | 2015-05-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter. Biochemistry, 54, 2015
|
|