4NXU
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![BU of 4nxu by Molmil](/molmil-images/mine/4nxu) | Crystal structure of the cytosolic domain of human MiD51 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Mitochondrial dynamic protein MID51, ... | 著者 | Richter, V, Kvansakul, M, Ryan, M.T. | 登録日 | 2013-12-09 | 公開日 | 2013-12-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission. J.Cell Biol., 204, 2014
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4O3R
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![BU of 4o3r by Molmil](/molmil-images/mine/4o3r) | Crystal structure of human polymerase eta extending an 8-oxog dna lesion: post insertion of 8-oxog-da pair | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), DNA (5'-D(*CP*AP*TP*GP*(8OG)P*TP*GP*AP*CP*GP*CP*T)-3'), ... | 著者 | Patra, A, Egli, M. | 登録日 | 2013-12-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
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4O4I
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![BU of 4o4i by Molmil](/molmil-images/mine/4o4i) | Tubulin-Laulimalide-Epothilone A complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, EPOTHILONE A, ... | 著者 | Prota, A.E, Bargsten, K, Northcote, P.T, Marsh, M, Altmann, K.H, Miller, J.H, Diaz, J.F, Steinmetz, M.O. | 登録日 | 2013-12-18 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of microtubule stabilization by laulimalide and peloruside a. Angew.Chem.Int.Ed.Engl., 53, 2014
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4NVI
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4NXX
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4NY6
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![BU of 4ny6 by Molmil](/molmil-images/mine/4ny6) | Neutron structure of leucine and valine methyl protonated type III antifreeze | 分子名称: | Type-3 ice-structuring protein HPLC 12 | 著者 | Fisher, S.J, Blakeley, M.P, Howard, E.I, Petite-Haertlein, I, Haertlein, M, Mitschler, A, Cousido-Siah, A, Salvaya, A.G, Popov, A, Muller-Dieckmann, C, Petrova, T, Podjarny, A.D. | 登録日 | 2013-12-10 | 公開日 | 2014-12-24 | 最終更新日 | 2024-02-28 | 実験手法 | NEUTRON DIFFRACTION (1.05 Å), X-RAY DIFFRACTION | 主引用文献 | Perdeuteration: improved visualization of solvent structure in neutron macromolecular crystallography. Acta Crystallogr.,Sect.D, 70, 2014
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4O25
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![BU of 4o25 by Molmil](/molmil-images/mine/4o25) | Structure of Wild Type Mus musculus Rheb bound to GTP | 分子名称: | GTP-binding protein Rheb, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | 著者 | Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M. | 登録日 | 2013-12-16 | 公開日 | 2014-03-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR). J.Biol.Chem., 289, 2014
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1SAU
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![BU of 1sau by Molmil](/molmil-images/mine/1sau) | The Gamma subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus at 1.1 A resolution | 分子名称: | sulfite reductase, desulfoviridin-type subunit gamma | 著者 | Mander, G.J, Weiss, M.S, Hedderich, R, Kahnt, J, Ermler, U, Warkentin, E. | 登録日 | 2004-02-09 | 公開日 | 2005-02-15 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Determination of a novel structure by a combination of long-wavelength sulfur phasing and radiation-damage-induced phasing. Acta Crystallogr.,Sect.D, 60, 2004
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4O2C
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![BU of 4o2c by Molmil](/molmil-images/mine/4o2c) | An Nt-acetylated peptide complexed with HLA-B*3901 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ... | 著者 | Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F. | 登録日 | 2013-12-17 | 公開日 | 2014-07-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation J.Immunol., 192, 2014
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4O2L
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![BU of 4o2l by Molmil](/molmil-images/mine/4o2l) | Structure of Mus musculus Rheb G63A mutant bound to GTP | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GTP-binding protein Rheb, ... | 著者 | Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M. | 登録日 | 2013-12-17 | 公開日 | 2014-03-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR). J.Biol.Chem., 289, 2014
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4O32
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![BU of 4o32 by Molmil](/molmil-images/mine/4o32) | Structure of a malarial protein | 分子名称: | CHLORIDE ION, Thioredoxin | 著者 | Egea, P.F, Koehl, A, Peng, M, Cascio, D. | 登録日 | 2013-12-17 | 公開日 | 2014-12-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.196 Å) | 主引用文献 | Crystal structure and solution characterization of the thioredoxin-2 from Plasmodium falciparum, a constituent of an essential parasitic protein export complex. Biochem.Biophys.Res.Commun., 456, 2015
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4O5X
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![BU of 4o5x by Molmil](/molmil-images/mine/4o5x) | O6-carboxymethylguanine in DNA forms a sequence context dependent wobble base pair structure with thymine. | 分子名称: | 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*(C6G)P*AP*AP*TP*TP*TP*GP*CP*G)-3'), MAGNESIUM ION | 著者 | Zhang, F, Tsunoda, M, Suzuki, K, Kikuchi, Y, Wilkinson, O, Millington, C.L, Margison, G.P, Williams, D.M, Takenaka, A. | 登録日 | 2013-12-20 | 公開日 | 2014-07-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | O(6)-Carboxymethylguanine in DNA forms a sequence context-dependent wobble base-pair structure with thymine Acta Crystallogr.,Sect.D, 70, 2014
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4NVA
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4NVL
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4NVH
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4NWX
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![BU of 4nwx by Molmil](/molmil-images/mine/4nwx) | Crystal structure of phosphoglycerate mutase from Staphylococcus aureus in 2-phosphoglyceric acid bound form | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, 2-PHOSPHOGLYCERIC ACID, ... | 著者 | Roychowdhury, A, Kundu, A, Bose, M, Gujar, A, Das, A.K. | 登録日 | 2013-12-07 | 公開日 | 2015-01-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism Febs J., 282, 2015
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4NZB
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![BU of 4nzb by Molmil](/molmil-images/mine/4nzb) | NS9283 bound to Ls-AChBP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl]benzonitrile, ACETATE ION, ... | 著者 | Olsen, J.A, Kastrup, J.S, Gajhede, M. | 登録日 | 2013-12-11 | 公開日 | 2014-07-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at alpha 4 beta 2 nicotinic acetylcholine receptors. J.Biol.Chem., 289, 2014
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4O26
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3Q31
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![BU of 3q31 by Molmil](/molmil-images/mine/3q31) | Structure of fungal alpha Carbonic Anhydrase from Aspergillus oryzae | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carbonic anhydrase, D-MALATE, ... | 著者 | Cuesta-Seijo, J.A, Borchert, M.S, Navarro-Poulsen, J.C, Schnorr, K.M, Leggio, L.L. | 登録日 | 2010-12-21 | 公開日 | 2011-03-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | 主引用文献 | Structure of fungal alpha Carbonic Anhydrase from Aspergillus oryzae To be Published
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4NVK
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![BU of 4nvk by Molmil](/molmil-images/mine/4nvk) | Predicting protein conformational response in prospective ligand discovery. | 分子名称: | Cytochrome c peroxidase, N~2~,N~2~-diethylquinazoline-2,4-diamine, PHOSPHATE ION, ... | 著者 | Fischer, M, Fraser, J.S. | 登録日 | 2013-12-05 | 公開日 | 2013-12-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery. Nat Chem, 6, 2014
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4NXW
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4NPV
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![BU of 4npv by Molmil](/molmil-images/mine/4npv) | Crystal structure of human PDE1B bound to inhibitor 7A (6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine) | 分子名称: | 6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine, Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, MAGNESIUM ION, ... | 著者 | Pandit, J, Evdomikov, A, Mansour, M, Simons, S. | 登録日 | 2013-11-22 | 公開日 | 2014-07-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Small-molecule phosphodiesterase probes: discovery of potent and selective CNS-penetrable quinazoline inhibitors of PDE1 MEDCHEMCOMM, 2014
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4NQU
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![BU of 4nqu by Molmil](/molmil-images/mine/4nqu) | anti-parallel Fc-knob (T366W) homodimer | 分子名称: | Ig gamma-1 chain C region, SULFATE ION | 著者 | Eigenbrot, C, Ultsch, M. | 登録日 | 2013-11-25 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2-CH3 Hydrophobic Interaction. J.Mol.Biol., 426, 2014
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3UWK
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![BU of 3uwk by Molmil](/molmil-images/mine/3uwk) | Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation | 分子名称: | 1-methyl-6-phenyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one, MAGNESIUM ION, Thymidylate kinase | 著者 | Choi, J.Y, Plummer, M.S, Starr, J, Desbonnet, C.R, Soutter, H.H, Chang, J, Miller, J.R, Dillman, K, Miller, A.A, Roush, W.R. | 登録日 | 2011-12-02 | 公開日 | 2012-02-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation. J.Med.Chem., 55, 2012
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4NBZ
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![BU of 4nbz by Molmil](/molmil-images/mine/4nbz) | Crystal Structure of TcdA-A1 Bound to A26.8 VHH | 分子名称: | A26.8 VHH, TcdA | 著者 | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | 登録日 | 2013-10-23 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. J.Biol.Chem., 289, 2014
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