2A3C
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![BU of 2a3c by Molmil](/molmil-images/mine/2a3c) | Crystal structure of Aspergillus fumigatus chitinase B1 in complex with pentoxifylline | 分子名称: | 3,7-DIMETHYL-1-(5-OXOHEXYL)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE, SULFATE ION, chitinase | 著者 | Rao, F.V, Andersen, O.A, Vora, K.A, DeMartino, J.A, van Aalten, D.M.F. | 登録日 | 2005-06-24 | 公開日 | 2005-09-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Methylxanthine drugs are chitinase inhibitors: investigation of inhibition and binding modes. Chem.Biol., 12, 2005
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2CBJ
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![BU of 2cbj by Molmil](/molmil-images/mine/2cbj) | Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc | 分子名称: | CHLORIDE ION, HYALURONIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE | 著者 | Rao, F.V, Dorfmueller, H.C, Villa, F, Allwood, M, Eggleston, I.M, van Aalten, D.M.F. | 登録日 | 2006-01-05 | 公開日 | 2006-02-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis. EMBO J., 25, 2006
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2CLO
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![BU of 2clo by Molmil](/molmil-images/mine/2clo) | Tryptophan Synthase (external aldimine state) in complex with (naphthalene-2'-sulfonyl)-2-amino-1-ethylphosphate (F19) | 分子名称: | 2-[(2-NAPHTHYLSULFONYL)AMINO]ETHYL DIHYDROGEN PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ... | 著者 | Ngo, H, Kimmich, N, Harris, R, Niks, D, Blumenstein, L, Kulik, V, Barends, T.R, Schlichting, I, Dunn, M.F. | 登録日 | 2006-04-28 | 公開日 | 2007-06-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Allosteric Regulation of Substrate Channeling in Tryptophan Synthase: Modulation of the L-Serine Reaction in Stage I of the Beta-Reaction by Alpha-Site Ligands. Biochemistry, 46, 2007
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2CLM
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![BU of 2clm by Molmil](/molmil-images/mine/2clm) | Tryptophan Synthase (external aldimine state) in complex with N-(4'- trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) | 分子名称: | 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ... | 著者 | Ngo, H, Kimmich, N, Harris, R, Niks, D, Blumenstein, L, Kulik, V, Barends, T.R, Schlichting, I, Dunn, M.F. | 登録日 | 2006-04-28 | 公開日 | 2007-06-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Allosteric Regulation of Substrate Channeling in Tryptophan Synthase: Modulation of the L-Serine Reaction in Stage I of the Beta-Reaction by Alpha-Site Ligands. Biochemistry, 46, 2007
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1PFT
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![BU of 1pft by Molmil](/molmil-images/mine/1pft) | N-TERMINAL DOMAIN OF TFIIB, NMR | 分子名称: | TFIIB, ZINC ION | 著者 | Zhu, W, Zeng, Q, Colangelo, C.M, Lewis, L.M, Summers, M.F, Scott, R.A. | 登録日 | 1996-03-27 | 公開日 | 1996-08-17 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The N-terminal domain of TFIIB from Pyrococcus furiosus forms a zinc ribbon. Nat.Struct.Biol., 3, 1996
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456C
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![BU of 456c by Molmil](/molmil-images/mine/456c) | CRYSTAL STRUCTURE OF COLLAGENASE-3 (MMP-13) COMPLEXED TO A DIPHENYL-ETHER SULPHONE BASED HYDROXAMIC ACID | 分子名称: | 2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO-PYRAN-4-YL}-N-HYDROXY-ACETAMIDE, CALCIUM ION, MMP-13, ... | 著者 | Lovejoy, B, Welch, A, Carr, S, Luong, C, Broka, C, Hendricks, R.T, Campbell, J, Walker, K, Martin, R, Van Wart, H, Browner, M.F. | 登録日 | 1998-08-06 | 公開日 | 1999-08-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of MMP-1 and -13 reveal the structural basis for selectivity of collagenase inhibitors. Nat.Struct.Biol., 6, 1999
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4AEH
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![BU of 4aeh by Molmil](/molmil-images/mine/4aeh) | Crystal structure of the anti-AaHI Fab9C2 antibody | 分子名称: | FAB ANTIBODY, HEAVY CHAIN, LIGHT CHAIN | 著者 | Fabrichny, I.P, Mondielli, G, Conrod, S, Martin-Eauclaire, M.F, Bourne, Y, Marchot, P. | 登録日 | 2012-01-10 | 公開日 | 2012-03-07 | 最終更新日 | 2012-05-02 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Insights Into Antibody Sequestering and Neutralizing of Na+-Channel & [Alpha]-Type Modulator from Old-World Scorpion Venom J.Biol.Chem., 287, 2012
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1PI7
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![BU of 1pi7 by Molmil](/molmil-images/mine/1pi7) | Structure of the channel-forming trans-membrane domain of Virus protein "u" (Vpu) from HIV-1 | 分子名称: | VPU protein | 著者 | Park, S.H, Mrse, A.A, Nevzorov, A.A, Mesleh, M.F, Oblatt-Montal, M, Montal, M, Opella, S.J. | 登録日 | 2003-05-29 | 公開日 | 2003-11-11 | 最終更新日 | 2024-05-22 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Three-dimensional structure of the channel-forming trans-membrane domain of virus protein "u" (Vpu) from HIV-1 J.Mol.Biol., 333, 2003
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3FDR
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![BU of 3fdr by Molmil](/molmil-images/mine/3fdr) | Crystal structure of TDRD2 | 分子名称: | Tudor and KH domain-containing protein | 著者 | Amaya, M.F, Adams, M.A, Guo, Y, Li, Y, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2008-11-26 | 公開日 | 2009-01-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi Proc.Natl.Acad.Sci.USA, 106, 2009
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4BEX
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![BU of 4bex by Molmil](/molmil-images/mine/4bex) | Structure of human Cofilin1 | 分子名称: | COFILIN-1 | 著者 | Klejnot, M, Gabrielsen, M, Cameron, J, Mleczak, A, Talapatra, S.K, Kozielski, F, Pannifer, A, Olson, M.F. | 登録日 | 2013-03-12 | 公開日 | 2013-08-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Analysis of the Human Cofilin1 Structure Reveals Conformational Changes Required for Actin-Binding Acta Crystallogr.,Sect.D, 69, 2013
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3FFE
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![BU of 3ffe by Molmil](/molmil-images/mine/3ffe) | Structure of Achromobactin Synthetase Protein D, (AcsD) | 分子名称: | AcsD | 著者 | McMahon, S.A, Liu, H, Carter, L, Oke, M, Johnson, K.A, Schmelz, S, Challis, G.L, White, M.F, Naismith, J.H, Scottish Structural Proteomics Facility (SSPF) | 登録日 | 2008-12-03 | 公開日 | 2009-02-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis Nat.Chem.Biol., 5, 2009
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4BHL
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![BU of 4bhl by Molmil](/molmil-images/mine/4bhl) | Crystal structure of Litopenaeus vannamei arginine kinase in binary complex with arginine | 分子名称: | ARGININE, ARGININE KINASE, BETA-MERCAPTOETHANOL | 著者 | Lopez-Zavala, A.A, Garcia-Orozco, K.D, Carrasco-Miranda, J.S, Hernandez-Flores, J.M, Sugich-Miranda, R, Velazquez-Contreras, E.F, Criscitiello, M.F, Brieba, L.G, Rudino-Pinera, E, Sotelo-Mundo, R.R. | 登録日 | 2013-04-03 | 公開日 | 2013-09-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of Shrimp Arginine Kinase in Binary Complex with Arginine-A Molecular View of the Phosphagen Precursor Binding to the Enzyme. J.Bioenerg.Biomembr., 45, 2013
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4BJU
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![BU of 4bju by Molmil](/molmil-images/mine/4bju) | Genetic and structural validation of Aspergillus fumigatus N- acetylphosphoglucosamine mutase as an antifungal target | 分子名称: | MAGNESIUM ION, N-ACETYLGLUCOSAMINE-PHOSPHATE MUTASE | 著者 | Fang, W, Raimi, O.G, Hurtado Guerrero, R, van Aalten, D.M.F. | 登録日 | 2013-04-19 | 公開日 | 2013-05-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Genetic and Structural Validation of Aspergillus Fumigatus N-Acetylphosphoglucosamine Mutase as an Antifungal Target. Biosci.Rep, 33, 2013
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4B8T
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![BU of 4b8t by Molmil](/molmil-images/mine/4b8t) | RNA BINDING PROTEIN Solution structure of the third KH domain of KSRP in complex with the G-rich target sequence. | 分子名称: | 5'-R(*AP*GP*GP*GP*UP)-3', KH-TYPE SPLICING REGULATORY PROTEIN | 著者 | Nicastro, G, Garcia-Mayoral, M.F, Hollingworth, D, Kelly, G, Martin, S.R, Briata, P, Gherzi, R, Ramos, A. | 登録日 | 2012-08-30 | 公開日 | 2012-11-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Noncanonical G Recognition Mediates Ksrp Regulation of Let-7 Biogenesis Nat.Struct.Mol.Biol., 19, 2012
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1OKZ
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![BU of 1okz by Molmil](/molmil-images/mine/1okz) | Structure of human PDK1 kinase domain in complex with UCN-01 | 分子名称: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1, 7-HYDROXYSTAUROSPORINE, GLYCEROL, ... | 著者 | Komander, D, Kular, G.S, Alessi, D.R, Van Aalten, D.M.F. | 登録日 | 2003-08-01 | 公開日 | 2004-07-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structural Basis for Ucn-01 (7-Hydroxystaurosporine) Specificity and Pdk1 (3-Phosphoinositide-Dependent Protein Kinase-1) Inhibition Biochem.J., 375, 2003
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1OKY
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![BU of 1oky by Molmil](/molmil-images/mine/1oky) | Structure of human PDK1 kinase domain in complex with staurosporine | 分子名称: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1, GLYCEROL, STAUROSPORINE, ... | 著者 | Komander, D, Kular, G.S, Alessi, D.R, Van Aalten, D.M.F. | 登録日 | 2003-08-01 | 公開日 | 2004-07-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis for Ucn-01 (7-Hydroxystaurosporine) Specificity and Pdk1 (3-Phosphoinositide-Dependent Protein Kinase-1) Inhibition Biochem.J., 375, 2003
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4BOJ
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1OGB
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![BU of 1ogb by Molmil](/molmil-images/mine/1ogb) | Chitinase b from Serratia marcescens mutant D142N | 分子名称: | CHITINASE B, GLYCEROL, SULFATE ION | 著者 | Vaaje-Kolstad, G, Houston, D.R, Rao, F.V, Peter, M.G, Synstad, B, van Aalten, D.M.F, Eijsink, V.G.H. | 登録日 | 2003-04-29 | 公開日 | 2004-04-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of the D142N Mutant of the Family 18 Chitinase Chib from Serratia Marcescens and its Complex with Allosamidin Biochim.Biophys.Acta, 1696, 2004
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4BV4
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![BU of 4bv4 by Molmil](/molmil-images/mine/4bv4) | Structure and allostery in Toll-Spatzle recognition | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN SPAETZLE C-106, PROTEIN TOLL, ... | 著者 | Lewis, M.F, Arnot, C.J, Beeston, H, McCoy, A, Ashcroft, A.E, Gay, N.J, Gangloff, M. | 登録日 | 2013-06-24 | 公開日 | 2013-12-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Cytokine Spatzle Binds to the Drosophila Immunoreceptor Toll with a Neurotrophin-Like Specificity and Couples Receptor Activation. Proc.Natl.Acad.Sci.USA, 110, 2013
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1QRJ
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![BU of 1qrj by Molmil](/molmil-images/mine/1qrj) | Solution structure of htlv-i capsid protein | 分子名称: | HTLV-I CAPSID PROTEIN | 著者 | Khorasanizadeh, S, Campos-Olivas, R, Clark, C.A, Summers, M.F. | 登録日 | 1999-06-14 | 公開日 | 1999-07-13 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Sequence-specific 1H, 13C and 15N chemical shift assignment and secondary structure of the HTLV-I capsid protein. J.Biomol.NMR, 14, 1999
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1QI9
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![BU of 1qi9 by Molmil](/molmil-images/mine/1qi9) | X-RAY SIRAS STRUCTURE DETERMINATION OF A VANADIUM-DEPENDENT HALOPEROXIDASE FROM ASCOPHYLLUM NODOSUM AT 2.0 A RESOLUTION | 分子名称: | VANADATE ION, Vanadium-dependent bromoperoxidase | 著者 | Weyand, M, Hecht, H.-J, Kiess, M, Liaud, M.F, Vilter, H, Schomburg, D. | 登録日 | 1999-06-10 | 公開日 | 2000-06-10 | 最終更新日 | 2023-06-07 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | X-ray structure determination of a vanadium-dependent haloperoxidase from Ascophyllum nodosum at 2.0 A resolution. J.Mol.Biol., 293, 1999
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4C3W
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![BU of 4c3w by Molmil](/molmil-images/mine/4c3w) | Vanadium(IV)-Picolinate Complexed with Lysozyme | 分子名称: | ACETATE ION, CHLORIDE ION, LYSOZYME C, ... | 著者 | Santos, M.F.A, Correia, I, Oliveira, A.R, Garribba, E, Pessoa, J.C, Romao, M.J, Santos-Silva, T. | 登録日 | 2013-08-28 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Vanadium Complexes as Prospective Therapeutics: Structural Characterization of a V(Iv) Lysozyme Adduct Eur.J.Inorg.Chem., 21, 2014
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3HHT
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![BU of 3hht by Molmil](/molmil-images/mine/3hht) | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability | 分子名称: | CHLORIDE ION, COBALT (III) ION, Nitrile hydratase alpha subunit, ... | 著者 | Van Wyk, J.C, Sewell, B.T, Cowan, D.A, Sayed, M.F, Tsekoa, T.L, Tastan Bishop, A.O. | 登録日 | 2009-05-17 | 公開日 | 2009-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | The high-resolution structure of a Cobalt containing nitrile hydratase To be published
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4BMA
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![BU of 4bma by Molmil](/molmil-images/mine/4bma) | structural of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase | 分子名称: | GLYCEROL, UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE | 著者 | Fang, W, Raimi, O.G, HurtadoGuerrero, R, vanAalten, D.M.F. | 登録日 | 2013-05-07 | 公開日 | 2013-05-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Genetic and Structural Validation of Aspergillus Fumigatus Udp-N-Acetylglucosamine Pyrophosphorylase as an Antifungal Target. Mol.Microbiol., 89, 2013
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1QL1
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