7ZRI
| Cryo-EM structure of the KdpFABC complex in a nucleotide-free E1 conformation loaded with K+ | Descriptor: | CARDIOLIPIN, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ... | Authors: | Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Stansfeld, P.J, Haenelt, I, Paulino, C. | Deposit date: | 2022-05-04 | Release date: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Inhibited KdpFABC transitions into an E1 off-cycle state. Elife, 11, 2022
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1AMM
| 1.2 ANGSTROM STRUCTURE OF GAMMA-B CRYSTALLIN AT 150K | Descriptor: | GAMMA B-CRYSTALLIN | Authors: | Kumaraswamy, V.S, Lindley, P.F, Slingsby, C, Glover, I.D. | Deposit date: | 1996-03-20 | Release date: | 1996-11-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | An eye lens protein-water structure: 1.2 A resolution structure of gammaB-crystallin at 150 K. Acta Crystallogr.,Sect.D, 52, 1996
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8BTM
| Structural and functional studies of geldanamycin amide synthase ShGdmF | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, GdmF | Authors: | Ewert, W, Zeilinger, C, Kirschning, A, Preller, M. | Deposit date: | 2022-11-29 | Release date: | 2024-06-12 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural and functional studies of geldanamycin amide synthase ShGdmF To Be Published
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8OSV
| Structural and functional studies of geldanamycin amide synthase ShGdmF | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Ewert, W, Zeilinger, C, Kirschning, A, Preller, M. | Deposit date: | 2023-04-20 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Structural and functional studies of geldanamycin amide synthase ShGdmF To Be Published
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8OSZ
| Structural and functional studies of geldanamycin amide synthase ShGdmF | Descriptor: | 3-aminophenol, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Ewert, W, Zeilinger, C, Kirschning, A, Preller, M. | Deposit date: | 2023-04-20 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Structural and functional studies of geldanamycin amide synthase ShGdmF To Be Published
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8OT2
| Structural and functional studies of geldanamycin amide synthase ShGdmF | Descriptor: | 1,2-ETHANEDIOL, 3-azanyl-5-methyl-phenol, ACETATE ION, ... | Authors: | Ewert, W, Zeilinger, C, Kirschning, A, Preller, M. | Deposit date: | 2023-04-20 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural and functional studies of geldanamycin amide synthase ShGdmF To Be Published
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3MQP
| Crystal Structure of human BFL-1 in complex with NOXA BH3 peptide, Northeast Structural Genomics Consortium Target HR2930 | Descriptor: | Bcl-2-related protein A1, Phorbol-12-myristate-13-acetate-induced protein 1 | Authors: | Guan, R, Xiao, R, Zhao, L, Acton, T.B, Gelinas, C, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-04-28 | Release date: | 2010-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Crystal Structure of human BFL-1 in complex with NOXA BH3 peptide To be Published
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4Y0Y
| Trypsin in complex with with BPTI | Descriptor: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | Authors: | Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. | Deposit date: | 2015-02-06 | Release date: | 2015-06-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chem Sci, 6, 2015
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4Y0Z
| Trypsin in complex with with BPTI mutant AMINOBUTYRIC ACID | Descriptor: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | Authors: | Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. | Deposit date: | 2015-02-06 | Release date: | 2015-06-24 | Last modified: | 2018-04-18 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chem Sci, 6, 2015
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7AHD
| OpuA (E190Q) occluded | Descriptor: | ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B. | Deposit date: | 2020-09-24 | Release date: | 2020-11-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA. Sci Adv, 6, 2020
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7AHH
| OpuA inhibited inward-facing, SBD docked | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, ... | Authors: | Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B. | Deposit date: | 2020-09-24 | Release date: | 2020-11-25 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA. Sci Adv, 6, 2020
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7AHE
| OpuA inhibited inward facing | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component | Authors: | Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B. | Deposit date: | 2020-09-24 | Release date: | 2020-11-25 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA. Sci Adv, 6, 2020
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7B5D
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7B5E
| Structure of calcium-bound mTMEM16A(ac)-I551A chloride channel at 4.1 A resolution | Descriptor: | Anoctamin-1, CALCIUM ION | Authors: | Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R. | Deposit date: | 2020-12-03 | Release date: | 2021-02-10 | Last modified: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Gating the pore of the calcium-activated chloride channel TMEM16A. Nat Commun, 12, 2021
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7B5C
| Structure of calcium-bound mTMEM16A(ac) chloride channel at 3.7 A resolution | Descriptor: | Anoctamin-1, CALCIUM ION | Authors: | Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R. | Deposit date: | 2020-12-03 | Release date: | 2021-02-10 | Last modified: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Gating the pore of the calcium-activated chloride channel TMEM16A. Nat Commun, 12, 2021
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7AHC
| OpuA apo inward-facing | Descriptor: | ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component | Authors: | Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B. | Deposit date: | 2020-09-24 | Release date: | 2020-11-25 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA. Sci Adv, 6, 2020
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4Y11
| Trypsin in complex with with BPTI mutant (2S)-2-amino-4,4,4-trifluorobutanoic acid | Descriptor: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | Authors: | Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. | Deposit date: | 2015-02-06 | Release date: | 2015-06-24 | Last modified: | 2018-04-18 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chem Sci, 6, 2015
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4Y10
| Trypsin in complex with with BPTI mutant (2S)-2-amino-4,4-difluorobutanoic acid | Descriptor: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | Authors: | Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. | Deposit date: | 2015-02-06 | Release date: | 2015-06-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Fluorine teams up with water to restore inhibitor activity to mutant BPTI. Chem Sci, 6, 2015
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8ON8
| Apo Malacoceros FaNaC1 in lipid nanodiscs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FMRFamide-gated sodium channel 1 | Authors: | Kalienkova, V, Dandamudi, M, Paulino, C, Lynagh, T. | Deposit date: | 2023-04-01 | Release date: | 2024-02-14 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for excitatory neuropeptide signaling. Nat.Struct.Mol.Biol., 31, 2024
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8ON9
| ASSFVRIa-bound Malacoceros FaNaC1 in lipid nanodiscs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ASSFVRIamide, ... | Authors: | Kalienkova, V, Dandamudi, M, Paulino, C, Lynagh, T. | Deposit date: | 2023-04-01 | Release date: | 2024-02-14 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis for excitatory neuropeptide signaling. Nat.Struct.Mol.Biol., 31, 2024
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8ON7
| FMRFa-bound Malacoceros FaNaC1 in lipid nanodiscs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FMRFamide, ... | Authors: | Kalienkova, V, Dandamudi, M, Paulino, C, Lynagh, T. | Deposit date: | 2023-04-01 | Release date: | 2024-02-14 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural basis for excitatory neuropeptide signaling. Nat.Struct.Mol.Biol., 31, 2024
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8ONA
| FMRFa-bound Malacoceros FaNaC1 in lipid nanodiscs in presence of diminazene | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FMRFamide, neuropeptide, ... | Authors: | Kalienkova, V, Dandamudi, M, Paulino, C, Lynagh, T. | Deposit date: | 2023-04-01 | Release date: | 2024-02-14 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for excitatory neuropeptide signaling. Nat.Struct.Mol.Biol., 31, 2024
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1AFE
| HUMAN ALPHA-THROMBIN INHIBITION BY CBZ-PRO-AZALYS-ONP | Descriptor: | 2-[N'-(4-AMINO-BUTYL)-HYDRAZINOCARBONYL]-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER, 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ... | Authors: | De Simone, G, Balliano, G, Milla, P, Gallina, C, Giordano, C, Tarricone, C, Rizzi, M, Bolognesi, M, Ascenzi, P. | Deposit date: | 1997-03-06 | Release date: | 1997-12-03 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study. J.Mol.Biol., 269, 1997
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1W72
| Crystal structure of HLA-A1:MAGE-A1 in complex with Fab-Hyb3 | Descriptor: | BETA-2-MICROGLOBULIN, GLYCEROL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | Authors: | Hulsmeyer, M, Chames, P, Hillig, R.C, Stanfield, R.L, Held, G, Coulie, P.G, Alings, C, Wille, G, Saenger, W, Uchanska-Ziegler, B, Hoogenboom, H.R, Ziegler, A. | Deposit date: | 2004-08-27 | Release date: | 2004-11-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A Major Histocompatibility Complex.Peptide- Restricted Antibody and T Cell Receptor Molecules Recognize Their Target by Distinct Binding Modes: Crystal Structure of Human Leukocyte Antigen (Hla)-A1.Mage-A1 in Complex with Fab-Hyb3 J.Biol.Chem., 280, 2005
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1AE8
| HUMAN ALPHA-THROMBIN INHIBITION BY EOC-D-PHE-PRO-AZALYS-ONP | Descriptor: | 1-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ... | Authors: | De Simone, G, Balliano, G, Milla, P, Gallina, C, Giordano, C, Tarricone, C, Rizzi, M, Bolognesi, M, Ascenzi, P. | Deposit date: | 1997-03-06 | Release date: | 1997-12-03 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study. J.Mol.Biol., 269, 1997
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