6B0V
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![BU of 6b0v by Molmil](/molmil-images/mine/6b0v) | Crystal Structure of small molecule ARS-107 covalently bound to K-Ras G12C | 分子名称: | 1-[3-(4-{[(4,5-dichloro-2-hydroxyphenyl)amino]acetyl}piperazin-1-yl)azetidin-1-yl]propan-1-one, CALCIUM ION, GTPase KRas, ... | 著者 | Hansen, R, Peters, U, Babbar, A, Chen, Y, Feng, J, Janes, M.R, Li, L.-S, Ren, P, Liu, Y, Zarrinkar, P.P. | 登録日 | 2017-09-15 | 公開日 | 2018-05-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | The reactivity-driven biochemical mechanism of covalent KRASG12Cinhibitors. Nat. Struct. Mol. Biol., 25, 2018
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3UA3
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![BU of 3ua3 by Molmil](/molmil-images/mine/3ua3) | Crystal Structure of Protein Arginine Methyltransferase PRMT5 in complex with SAH | 分子名称: | Protein arginine N-methyltransferase 5, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Sun, L, Wang, M, Lv, Z, Yang, N, Liu, Y, Bao, S, Gong, W, Xu, R.M. | 登録日 | 2011-10-20 | 公開日 | 2011-12-14 | 最終更新日 | 2011-12-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural insights into protein arginine symmetric dimethylation by PRMT5 Proc.Natl.Acad.Sci.USA, 108, 2011
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4NRS
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![BU of 4nrs by Molmil](/molmil-images/mine/4nrs) | Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase (E202A mutant) from Rhizomucor miehei in complex with mannobiose | 分子名称: | Exo-beta-1,4-mannosidase, beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose | 著者 | Jiang, Z.Q, Zhou, P, Yang, S.Q, Liu, Y, Yan, Q.J. | 登録日 | 2013-11-27 | 公開日 | 2014-11-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase. Acta Crystallogr.,Sect.D, 70, 2014
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4QP0
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![BU of 4qp0 by Molmil](/molmil-images/mine/4qp0) | Crystal Structure Analysis of the Endo-1,4-beta-mannanase from Rhizomucor miehei | 分子名称: | Endo-beta-mannanase, SULFATE ION | 著者 | Zheng, Q.J, Peng, Z, Liu, Y, Yan, Q.J, Chen, Z.Z, Qin, Z. | 登録日 | 2014-06-22 | 公開日 | 2014-11-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase. Acta Crystallogr.,Sect.D, 70, 2014
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7E29
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![BU of 7e29 by Molmil](/molmil-images/mine/7e29) | Crystal Structure of Saccharomyces cerevisiae Ioc4 PWWP domain fused with MBP | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,ISWI one complex protein 4, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Li, J, Smolle, M, Liang, H, Liu, Y. | 登録日 | 2021-02-05 | 公開日 | 2022-02-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | 主引用文献 | H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function. Nucleic Acids Res., 50, 2022
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1WP8
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![BU of 1wp8 by Molmil](/molmil-images/mine/1wp8) | crystal structure of Hendra Virus fusion core | 分子名称: | Fusion glycoprotein F0,Fusion glycoprotein F0 | 著者 | Xu, Y, Liu, Y, Lou, Z, Su, N, Bai, Z, Gao, G.F, Rao, Z. | 登録日 | 2004-08-31 | 公開日 | 2005-11-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of Nipah and Hendra virus fusion core proteins FEBS J., 273, 2006
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8TXQ
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![BU of 8txq by Molmil](/molmil-images/mine/8txq) | CryoEM structure of non-neutralizing antibody CBH-4B in complex with Hepatitis C virus envelope glycoprotein E2 | 分子名称: | CBH-4B Heavy chain, CBH-4B Light chain, envelope glycoprotein E2 | 著者 | Shahid, S, Liqun, J, Liu, Y, Hasan, S.S, Mariuzza, R.A. | 登録日 | 2023-08-24 | 公開日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | CryoEM structure of non-neutralizing antibody CBH-4B in complex with Hepatitis C virus envelope glycoprotein E2 To Be Published
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7D3X
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7D3W
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2LQ9
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![BU of 2lq9 by Molmil](/molmil-images/mine/2lq9) | |
2JVC
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2N3J
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![BU of 2n3j by Molmil](/molmil-images/mine/2n3j) | Solution Structure of the alpha-crystallin domain from the redox-sensitive chaperone, HSPB1 | 分子名称: | Heat shock protein beta-1 | 著者 | Rajagopal, P, Liu, Y, Shi, L, Klevit, R.E. | 登録日 | 2015-06-03 | 公開日 | 2015-08-19 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the alpha-crystallin domain from the redox-sensitive chaperone, HSPB1. J.Biomol.Nmr, 63, 2015
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2OIG
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![BU of 2oig by Molmil](/molmil-images/mine/2oig) | Crystal structure of RS21-C6 core segment and dm5CTP complex | 分子名称: | 2'-DEOXY-5-METHYLCYTIDINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), RS21-C6 | 著者 | Wu, B, Liu, Y, Zhao, Q, Liao, S, Zhang, J, Bartlam, M, Chen, W, Rao, Z. | 登録日 | 2007-01-11 | 公開日 | 2007-03-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal Structure of RS21-C6, Involved in Nucleoside Triphosphate Pyrophosphohydrolysis J.Mol.Biol., 367, 2007
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2OIE
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![BU of 2oie by Molmil](/molmil-images/mine/2oie) | Crystal structure of RS21-C6 core segment RSCUT | 分子名称: | RS21-C6, SULFATE ION | 著者 | Wu, B, Liu, Y, Zhao, Q, Liao, S, Zhang, J, Bartlam, M, Chen, W, Rao, Z. | 登録日 | 2007-01-10 | 公開日 | 2007-03-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of RS21-C6, Involved in Nucleoside Triphosphate Pyrophosphohydrolysis J.Mol.Biol., 367, 2007
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2O0F
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![BU of 2o0f by Molmil](/molmil-images/mine/2o0f) | Docking of the modified RF3 X-ray structure into cryo-EM map of E.coli 70S ribosome bound with RF3 | 分子名称: | Peptide chain release factor 3 | 著者 | Gao, H, Zhou, Z, Rawat, U, Huang, C, Bouakaz, L, Wang, C, Liu, Y, Zavialov, A, Gursky, R, Sanyal, S, Ehrenberg, M, Frank, J, Song, H. | 登録日 | 2006-11-27 | 公開日 | 2007-07-24 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (15.5 Å) | 主引用文献 | RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors Cell(Cambridge,Mass.), 129, 2007
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2K5U
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7W7P
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5YDE
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![BU of 5yde by Molmil](/molmil-images/mine/5yde) | Crystal structure of a disease-related gene, hCDC73(1-111) | 分子名称: | Parafibromin | 著者 | Sun, W, Kuang, X.L, Liu, Y.P, Tian, L.F, Yan, X.X, Xu, W.Q. | 登録日 | 2017-09-13 | 公開日 | 2017-12-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.023 Å) | 主引用文献 | Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome Sci Rep, 7, 2017
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5YDF
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![BU of 5ydf by Molmil](/molmil-images/mine/5ydf) | Crystal structure of a disease-related gene, hCDC73(1-100) | 分子名称: | Parafibromin | 著者 | Sun, W, Kuang, X.L, Liu, Y.P, Tian, L.F, Yan, X.X, Xu, W.Q. | 登録日 | 2017-09-13 | 公開日 | 2017-12-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome Sci Rep, 7, 2017
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7XC4
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![BU of 7xc4 by Molmil](/molmil-images/mine/7xc4) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain 3 (SARS-unique domain-M) in complex with Oxaprozin | 分子名称: | 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid, Papain-like protease nsp3 | 著者 | Li, J, Liu, Y, Gao, J, Ruan, K. | 登録日 | 2022-03-22 | 公開日 | 2022-11-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Two Binding Sites of SARS-CoV-2 Macrodomain 3 Probed by Oxaprozin and Meclomen. J.Med.Chem., 65, 2022
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5YY8
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2K6S
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8JIF
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7WI7
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7X8M
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![BU of 7x8m by Molmil](/molmil-images/mine/7x8m) | NMR Solution Structure of the 2:1 Berberine-KRAS-G4 Complex | 分子名称: | BERBERINE, DNA (24-MER) | 著者 | Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y. | 登録日 | 2022-03-14 | 公開日 | 2022-09-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine. Nat Commun, 13, 2022
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