1AOL
 
 | | FRIEND MURINE LEUKEMIA VIRUS RECEPTOR-BINDING DOMAIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GP70, ZINC ION | | 著者 | Fass, D, Davey, R.A, Hamson, C.A, Kim, P.S, Cunningham, J.M, Berger, J.M. | | 登録日 | 1997-07-08 | | 公開日 | 1997-10-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution.
Science, 277, 1997
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1W8X
 | | Structural analysis of PRD1 | | 分子名称: | MAJOR CAPSID PROTEIN (PROTEIN P3), PROTEIN P16, PROTEIN P30, ... | | 著者 | Abrescia, N.G.A, Cockburn, J.J.B, Grimes, J.M, Sutton, G.C, Diprose, J.M, Butcher, S.J, Fuller, S.D, San Martin, C, Burnett, R.M, Stuart, D.I, Bamford, D.H, Bamford, J.K.H. | | 登録日 | 2004-10-01 | | 公開日 | 2004-11-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Insights Into Assembly from Structural Analysis of Bacteriophage Prd1.
Nature, 432, 2004
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1BYL
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3MWS
 | | Crystal Structure of Group N HIV-1 Protease | | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, HIV-1 Protease | | 著者 | Sayer, J.M, Agniswamy, J, Weber, I.T, Louis, J.M. | | 登録日 | 2010-05-06 | | 公開日 | 2011-03-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Autocatalytic maturation, physical/chemical properties, and crystal structure of group N HIV-1 protease: relevance to drug resistance.
Protein Sci., 19, 2010
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3RTP
 | | Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration | | 分子名称: | Mitogen-activated protein kinase 10, N-[4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide | | 著者 | Bowers, S, Truong, A.P, Neitz, R.J, Hom, R.K, Sealy, J.M, Probst, G.D, Quincy, Q, Peterson, B, Chan, W, Galemmo Jr, R.A, Konradi, A.W, Sham, H.L, Pan, H, Lin, M, Yao, N, Artis, D.R, Zhang, H, Chen, L, Dryer, M, Samant, B, Zmolek, W, Wong, K, Lorentzen, C, Goldbach, E, Tonn, G, Quinn, K.P, Sauer, J, Wright, S, Powell, K, Ruslim, L, Ren, Z, Bard, F, Yednock, T.A, Griswold-Prenne, I. | | 登録日 | 2011-05-03 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration.
Bioorg.Med.Chem.Lett., 21, 2011
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1DAZ
 | | Structural and kinetic analysis of drug resistant mutants of HIV-1 protease | | 分子名称: | HIV-1 PROTEASE (RETROPEPSIN), N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide | | 著者 | Mahalingam, B, Louis, J.M, Reed, C.C, Adomat, J.M, Krouse, J, Wang, Y.F, Harrison, R.W, Weber, I.T. | | 登録日 | 1999-11-01 | | 公開日 | 2000-05-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural and kinetic analysis of drug resistant mutants of HIV-1 protease.
Eur.J.Biochem., 263, 1999
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1BAI
 | | Crystal structure of Rous sarcoma virus protease in complex with inhibitor | | 分子名称: | N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE | | 著者 | Wu, J, Adomat, J.M, Ridky, T.W, Louis, J.M, Leis, J, Harrison, R.W, Weber, I.T. | | 登録日 | 1998-04-17 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for specificity of retroviral proteases.
Biochemistry, 37, 1998
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1DW6
 | | Structural and kinetic analysis of drug resistant mutants of HIV-1 protease | | 分子名称: | HIV-1 PROTEASE, N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide | | 著者 | Mahalingam, B, Louis, J.M, Reed, C.C, Adomat, J.M, Krouse, J, Wang, Y.F, Harrison, R.W, Weber, I.T. | | 登録日 | 2000-01-24 | | 公開日 | 2000-07-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Structural and kinetic analysis of drug resistant mutants of HIV-1 protease.
Eur.J.Biochem., 263, 1999
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1ERI
 | | X-RAY STRUCTURE OF THE DNA-ECO RI ENDONUCLEASE-DNA RECOGNITION COMPLEX: THE RECOGNITION NETWORK AND THE INTEGRATION OF RECOGNITION AND CLEAVAGE | | 分子名称: | DNA (5'-D(*TP*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), PROTEIN (ECO RI ENDONUCLEASE (E.C.3.1.21.4)) | | 著者 | Kim, Y, Grable, J.C, Love, R, Greene, P.J, Rosenberg, J.M. | | 登録日 | 1994-05-18 | | 公開日 | 1995-02-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Refinement of Eco RI endonuclease crystal structure: a revised protein chain tracing.
Science, 249, 1990
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3E4C
 | | Procaspase-1 zymogen domain crystal structure | | 分子名称: | Caspase-1, MAGNESIUM ION | | 著者 | Elliott, J.M, Rouge, L, Wiesmann, C, Scheer, J.M. | | 登録日 | 2008-08-11 | | 公開日 | 2008-12-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of procaspase-1 zymogen domain reveals insight into inflammatory caspase autoactivation
J.Biol.Chem., 284, 2009
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6G4U
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6G4I
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6G4K
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6G4V
 | | The solution NMR structure of [C18S,C24S]brevinin-1BYa in 33% trifluoroethanol | | 分子名称: | [C18S,C24S]brevinin-1BYa | | 著者 | Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M. | | 登録日 | 2018-03-28 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides.
Eur.Biophys.J., 48, 2019
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6G4X
 | | The solution NMR structure of [C18S,C24S]brevinin-1BYa in sodium dodecyl sulphate micelles | | 分子名称: | [C18S,C24S]brevinin-1BYa | | 著者 | Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M. | | 登録日 | 2018-03-28 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides.
Eur.Biophys.J., 48, 2019
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1PNC
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3FK3
 | | Structure of the Yeats Domain, Yaf9 | | 分子名称: | Protein AF-9 homolog | | 著者 | Wang, A.Y, Schulze, J.M, Skordalakes, E, Berger, J.M, Rine, J, Kobor, M.S. | | 登録日 | 2008-12-15 | | 公開日 | 2009-10-27 | | 最終更新日 | 2021-03-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation
Proc.Natl.Acad.Sci.USA, 106, 2009
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1PND
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3G7C
 | | Structure of the Phosphorylation Mimetic of Occludin C-term Tail | | 分子名称: | Occludin | | 著者 | Tash, B.R, Sundstrom, J.M, Murakami, T, Flanagan, J.M, Bewley, M.C, Antonetii, D.A. | | 登録日 | 2009-02-09 | | 公開日 | 2009-05-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification and analysis of occludin phosphosites: a combined mass spectrometry and bioinformatics approach.
J.PROTEOME RES., 8, 2009
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2CHY
 | | THREE-DIMENSIONAL STRUCTURE OF CHEY, THE RESPONSE REGULATOR OF BACTERIAL CHEMOTAXIS | | 分子名称: | CHEY | | 著者 | Mottonen, J.M, Stock, A.M, Stock, J.B, Schutt, C.E. | | 登録日 | 1990-05-17 | | 公開日 | 1990-07-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Three-dimensional structure of CheY, the response regulator of bacterial chemotaxis.
Nature, 337, 1989
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6I50
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2CPK
 | | CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF CYCLIC ADENOSINE MONOPHOSPHATE-DEPENDENT PROTEIN KINASE | | 分子名称: | PEPTIDE INHIBITOR 20-MER, cAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT | | 著者 | Knighton, D.R, Zheng, J, Teneyck, L.F, Ashford, V.A, Xuong, N.-H, Taylor, S.S, Sowadski, J.M. | | 登録日 | 1992-10-21 | | 公開日 | 1993-01-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase.
Science, 253, 1991
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6I2I
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2FDN
 | | 2[4FE-4S] FERREDOXIN FROM CLOSTRIDIUM ACIDI-URICI | | 分子名称: | FERREDOXIN, IRON/SULFUR CLUSTER | | 著者 | Dauter, Z, Wilson, K.S, Sieker, L.C, Meyer, J, Moulis, J.M. | | 登録日 | 1997-10-01 | | 公開日 | 1998-04-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (0.94 Å) | | 主引用文献 | Atomic resolution (0.94 A) structure of Clostridium acidurici ferredoxin. Detailed geometry of [4Fe-4S] clusters in a protein.
Biochemistry, 36, 1997
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1PYN
 | | DUAL-SITE POTENT, SELECTIVE PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR USING A LINKED FRAGMENT STRATEGY AND A MALONATE HEAD ON THE FIRST SITE | | 分子名称: | 2-(4-{2-TERT-BUTOXYCARBONYLAMINO-2-[4-(3-HYDROXY-2-METHOXYCARBONYL-PHENOXY)-BUTYLCARBAMOYL]-ETHYL}-PHENOXY)-MALONIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | | 著者 | Szczepankiewicz, B.G, Liu, G, Hajduk, P.J, Abad-Zapatero, C, Zhonghua, P, Lubben, T, Trevillyan, J.M, Stashko, M, Ballaron, S.J, Liang, H. | | 登録日 | 2003-07-09 | | 公開日 | 2003-09-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors.
Bioorg.Med.Chem.Lett., 13, 2003
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