2Y9G
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![BU of 2y9g by Molmil](/molmil-images/mine/2y9g) | High-resolution Structural Insights on the Sugar-recognition and Fusion Tag Properties of a Versatile b-Trefoil Lectin Domain | Descriptor: | GLYCEROL, HEMOLYTIC LECTIN LSLA, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, ... | Authors: | Angulo, I, Acebron, I, de las Rivas, B, Munoz, R, Rodriguez, J.I, Menendez, M, Garcia, P, Tateno, H, Goldstein, I.J, Perez-Agote, B, Mancheno, J.M. | Deposit date: | 2011-02-14 | Release date: | 2011-10-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | High-Resolution Structural Insights on the Sugar-Recognition and Fusion Tag Properties of a Versatile Beta-Trefoil Lectin Domain from the Mushroom Laetiporus Sulphureus. Glycobiology, 21, 2011
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1BJT
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![BU of 1bjt by Molmil](/molmil-images/mine/1bjt) | TOPOISOMERASE II RESIDUES 409-1201 | Descriptor: | TOPOISOMERASE II | Authors: | Fass, D, Bogden, C.E, Berger, J.M. | Deposit date: | 1998-06-29 | Release date: | 1999-05-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands. Nat.Struct.Biol., 6, 1999
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2YGC
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![BU of 2ygc by Molmil](/molmil-images/mine/2ygc) | |
4GB9
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![BU of 4gb9 by Molmil](/molmil-images/mine/4gb9) | Potent and Highly Selective Benzimidazole Inhibitors of PI3K-delta | Descriptor: | 2-[1-({2-[2-(dimethylamino)-1H-benzimidazol-1-yl]-9-methyl-6-(morpholin-4-yl)-9H-purin-8-yl}methyl)piperidin-4-yl]propan-2-ol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Authors: | Murray, J.M. | Deposit date: | 2012-07-26 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.438 Å) | Cite: | Potent and highly selective benzimidazole inhibitors of PI3-kinase delta. J.Med.Chem., 55, 2012
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2WC4
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![BU of 2wc4 by Molmil](/molmil-images/mine/2wc4) | Structure of family 1 beta-glucosidase from Thermotoga maritima in complex with 3-imino-2-thia-(+)-castanospermine | Descriptor: | (3Z,5S,6R,7S,8R,8aS)-3-(octylimino)hexahydro[1,3]thiazolo[3,4-a]pyridine-5,6,7,8-tetrol, 1,2-ETHANEDIOL, ACETATE ION, ... | Authors: | Aguilar, M, Gloster, T.M, Turkenburg, J.P, Garcia-Moreno, M.I, Ortiz Mellet, C, Davies, G.J, Garcia Fernandez, J.M. | Deposit date: | 2009-03-08 | Release date: | 2009-04-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Glycosidase Inhibition by Ring-Modified Castanospermine Analogues: Tackling Enzyme Selectivity by Inhibitor Tailoring. Org.Biomol.Chem., 7, 2009
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3L26
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![BU of 3l26 by Molmil](/molmil-images/mine/3l26) | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Polymerase cofactor VP35, ... | Authors: | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | Deposit date: | 2009-12-14 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat.Struct.Mol.Biol., 17, 2010
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4G31
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![BU of 4g31 by Molmil](/molmil-images/mine/4g31) | Crystal Structure of GSK6414 Bound to PERK (R587-R1092, delete A660-T867) at 2.28 A Resolution | Descriptor: | 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone, Eukaryotic translation initiation factor 2-alpha kinase 3, GLYCEROL | Authors: | Gampe, R.T, Axten, J.M. | Deposit date: | 2012-07-13 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK). J.Med.Chem., 55, 2012
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3L27
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![BU of 3l27 by Molmil](/molmil-images/mine/3l27) | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain R312A mutant | Descriptor: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | Authors: | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | Deposit date: | 2009-12-14 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat.Struct.Mol.Biol., 17, 2010
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1BL8
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![BU of 1bl8 by Molmil](/molmil-images/mine/1bl8) | POTASSIUM CHANNEL (KCSA) FROM STREPTOMYCES LIVIDANS | Descriptor: | POTASSIUM ION, PROTEIN (POTASSIUM CHANNEL PROTEIN) | Authors: | Doyle, D.A, Cabral, J.M, Pfuetzner, R.A, Kuo, A, Gulbis, J.M, Cohen, S.L, Chait, B.T, Mackinnon, R. | Deposit date: | 1998-07-23 | Release date: | 1998-07-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science, 280, 1998
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7T71
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![BU of 7t71 by Molmil](/molmil-images/mine/7t71) | Crystal Structure of Mevalonate 3,5-Bisphosphate Decarboxylase from Picrophilus Torridus | Descriptor: | Mevalonate 3,5-bisphosphate decarboxylase, OLEIC ACID | Authors: | Vinokur, J.M, Sawaya, M.R, Cascio, D, Collazo, M, Bowie, J.U. | Deposit date: | 2021-12-14 | Release date: | 2021-12-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystal structure of mevalonate 3,5-bisphosphate decarboxylase reveals insight into the evolution of decarboxylases in the mevalonate metabolic pathways. J.Biol.Chem., 298, 2022
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2WD1
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![BU of 2wd1 by Molmil](/molmil-images/mine/2wd1) | Human c-Met Kinase in complex with azaindole inhibitor | Descriptor: | 1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE, GAMMA-BUTYROLACTONE, HEPATOCYTE GROWTH FACTOR RECEPTOR | Authors: | Porter, J, Lumb, S, Franklin, R.J, Gascon-Simorte, J.M, Calmiano, M, Le Riche, K, Lallemand, B, Keyaerts, J, Edwards, H, Maloney, A, Delgado, J, King, L, Foley, A, Lecomte, F, Reuberson, J, Meier, C, Batchelor, M. | Deposit date: | 2009-03-19 | Release date: | 2009-04-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of 4-Azaindoles as Novel Inhibitors of C- met Kinase. Bioorg.Med.Chem.Lett., 19, 2009
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1MEY
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![BU of 1mey by Molmil](/molmil-images/mine/1mey) | CRYSTAL STRUCTURE OF A DESIGNED ZINC FINGER PROTEIN BOUND TO DNA | Descriptor: | CHLORIDE ION, CONSENSUS ZINC FINGER, DNA (5'-D(*AP*TP*GP*AP*GP*GP*CP*AP*GP*AP*AP*CP*T)-3'), ... | Authors: | Kim, C.A, Berg, J.M. | Deposit date: | 1996-09-27 | Release date: | 1997-03-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A 2.2 A Resolution Crystal Structure of a Designed Zinc Finger Protein Bound to DNA Nat.Struct.Biol., 3, 1996
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2X7P
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![BU of 2x7p by Molmil](/molmil-images/mine/2x7p) | The Conserved Candida albicans CA3427 Gene Product Defines a New Family of Proteins Exhibiting the Generic Periplasmic Binding Protein Structural Fold | Descriptor: | 2-(2-ETHOXYETHOXY)ETHANOL, ACETIC ACID, CALCIUM ION, ... | Authors: | Santini, S, Monchois, V, Mouz, N, Rousselle, T, Claverie, J.M, Abergel, C. | Deposit date: | 2010-03-03 | Release date: | 2011-03-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | The Conserved Candida Albicans Ca3427 Gene Product Defines a New Family of Proteins Exhibiting the Generic Periplasmic Binding Protein Structural Fold Plos One, 6, 2011
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2X6B
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![BU of 2x6b by Molmil](/molmil-images/mine/2x6b) | Potassium Channel from Magnetospirillum Magnetotacticum | Descriptor: | ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, BARIUM ION, PHOSPHOCHOLINE, ... | Authors: | Clarke, O.B, Caputo, A.T, Hill, A.P, Vandenberg, J.I, Smith, B.J, Gulbis, J.M. | Deposit date: | 2010-02-15 | Release date: | 2010-06-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels. Cell(Cambridge,Mass.), 141, 2010
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4GDO
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![BU of 4gdo by Molmil](/molmil-images/mine/4gdo) | Structure of a fragment of the rod domain of plectin | Descriptor: | Plectin | Authors: | De Pereda, J.M, Buey, R.M, Uson, I, Sammito, M.D, De Marino, I. | Deposit date: | 2012-08-01 | Release date: | 2013-09-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Exploiting tertiary structure through local folds for crystallographic phasing. Nat.Methods, 10, 2013
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4GET
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![BU of 4get by Molmil](/molmil-images/mine/4get) | Crystal structure of biogenic amine binding protein from Rhodnius prolixus | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Biogenic amine-binding protein | Authors: | Andersen, J.F, Chang, B.W, Xu, X, Mans, B.J, Ribeiro, J.M. | Deposit date: | 2012-08-02 | Release date: | 2013-01-02 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structure and ligand-binding properties of the biogenic amine-binding protein from the saliva of a blood-feeding insect vector of Trypanosoma cruzi. Acta Crystallogr.,Sect.D, 69, 2013
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4GE1
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![BU of 4ge1 by Molmil](/molmil-images/mine/4ge1) | Structure of the tryptamine complex of the amine binding protein of Rhodnius prolixus | Descriptor: | 2-(1H-INDOL-3-YL)ETHANAMINE, Biogenic amine-binding protein, GLYCEROL | Authors: | Andersen, J.F, Chang, B.W, Xu, X, Mans, B.J, Ribeiro, J.M. | Deposit date: | 2012-08-01 | Release date: | 2013-01-02 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure and ligand-binding properties of the biogenic amine-binding protein from the saliva of a blood-feeding insect vector of Trypanosoma cruzi. Acta Crystallogr.,Sect.D, 69, 2013
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2X1C
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![BU of 2x1c by Molmil](/molmil-images/mine/2x1c) | The crystal structure of precursor acyl coenzyme A:isopenicillin N acyltransferase from Penicillium chrysogenum | Descriptor: | ACYL-COENZYME, CHLORIDE ION, GLYCEROL, ... | Authors: | Bokhove, M, Yoshida, H, Hensgens, C.M.H, van der Laan, J.M, Sutherland, J.D, Dijkstra, B.W. | Deposit date: | 2009-12-23 | Release date: | 2010-03-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structures of an Isopenicillin N Converting Ntn-Hydrolase Reveal Different Catalytic Roles for the Active Site Residues of Precursor and Mature Enzyme. Structure, 18, 2010
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1HIX
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![BU of 1hix by Molmil](/molmil-images/mine/1hix) | CRYSTALLOGRAPHIC ANALYSES OF FAMILY 11 ENDO-BETA-1,4-XYLANASE XYL1 FROM STREPTOMYCES SP. S38 | Descriptor: | ENDO-1,4-BETA-XYLANASE | Authors: | Wouters, J, Georis, J, Dusart, J, Frere, J.M, Depiereux, E, Charlier, P. | Deposit date: | 2001-01-05 | Release date: | 2001-11-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystallographic Analysis of Family 11 Endo-[Beta]-1,4-Xylanase Xyl1 from Streptomyces Sp. S38 Acta Crystallogr.,Sect.D, 57, 2001
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4GLQ
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![BU of 4glq by Molmil](/molmil-images/mine/4glq) | Crystal Structure of the blue-light absorbing form of the Thermosynechococcus elongatus PixJ GAF-domain | Descriptor: | Methyl-accepting chemotaxis protein, Phycoviolobilin, blue light-absorbing form | Authors: | Burgie, E.S, Walker, J.M, Phillips Jr, G.N, Vierstra, R.D. | Deposit date: | 2012-08-14 | Release date: | 2013-01-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.772 Å) | Cite: | A Photo-Labile Thioether Linkage to Phycoviolobilin Provides the Foundation for the Blue/Green Photocycles in DXCF-Cyanobacteriochromes. Structure, 21, 2013
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4FX7
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![BU of 4fx7 by Molmil](/molmil-images/mine/4fx7) | |
4FYT
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![BU of 4fyt by Molmil](/molmil-images/mine/4fyt) | Human aminopeptidase N (CD13) in complex with amastatin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMASTATIN, ... | Authors: | Wong, A.H, Rini, J.M. | Deposit date: | 2012-07-05 | Release date: | 2012-09-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing. J.Biol.Chem., 287, 2012
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2MBR
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![BU of 2mbr by Molmil](/molmil-images/mine/2mbr) | MURB WILD TYPE, COMPLEX WITH ENOLPYRUVYL-UDP-N-ACETYLGLUCOSAMINE | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, URIDINE DIPHOSPHO-N-ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE, URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID | Authors: | Benson, T.E, Walsh, C.T, Hogle, J.M. | Deposit date: | 1996-11-08 | Release date: | 1997-04-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution. Biochemistry, 36, 1997
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4AE2
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![BU of 4ae2 by Molmil](/molmil-images/mine/4ae2) | Crystal structure of Human fibrillar procollagen type III C- propeptide trimer | Descriptor: | CALCIUM ION, COLLAGEN ALPHA-1(III) CHAIN, NITRATE ION | Authors: | Bourhis, J.M, Mariano, N, Zhao, Y, Harlos, K, Jones, E.Y, Moali, C, Aghajari, N, Hulmes, D.J. | Deposit date: | 2012-01-05 | Release date: | 2012-09-12 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural Basis of Fibrillar Collagen Trimerization and Related Genetic Disorders. Nat.Struct.Mol.Biol., 19, 2012
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6JB8
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![BU of 6jb8 by Molmil](/molmil-images/mine/6jb8) | Crystal structure of nanobody D3-L11 in complex with hen egg-white lysozyme | Descriptor: | CHLORIDE ION, GLYCEROL, Lysozyme C, ... | Authors: | Caaveiro, J.M.M, Tamura, H, Akiba, H, Tsumoto, K. | Deposit date: | 2019-01-25 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody. Sci Rep, 9, 2019
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