8EDK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8edk by Molmil](/molmil-images/mine/8edk) | Structure of C. elegans UNC-6 LamN and EGF domains | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Netrin unc-6, ... | Authors: | Priest, J.M, Ozkan, E. | Deposit date: | 2022-09-04 | Release date: | 2023-01-11 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into the formation of repulsive netrin guidance complexes. Sci Adv, 10, 2024
|
|
8EDC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8edc by Molmil](/molmil-images/mine/8edc) | Structure of C. elegans UNC-5 IG 1+2 Domains | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Netrin receptor unc-5, SULFATE ION | Authors: | Priest, J.M, Ozkan, E. | Deposit date: | 2022-09-04 | Release date: | 2023-01-11 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Structural insights into the formation of repulsive netrin guidance complexes. Sci Adv, 10, 2024
|
|
8ECO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8eco by Molmil](/molmil-images/mine/8eco) | Microbacterium phage Oxtober96 | Descriptor: | Major capsid protein | Authors: | Podgorski, J.M, White, S.J. | Deposit date: | 2022-09-02 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. Structure, 31, 2023
|
|
8EC2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ec2 by Molmil](/molmil-images/mine/8ec2) | Mycobacterium phage Adephagia | Descriptor: | Major capsid protein | Authors: | Podgorski, J.M, White, S.J. | Deposit date: | 2022-09-01 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. Structure, 31, 2023
|
|
8ECJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ecj by Molmil](/molmil-images/mine/8ecj) | Mycobacterium phage Cain | Descriptor: | Major capsid protein | Authors: | Podgorski, J.M, White, S.J. | Deposit date: | 2022-09-02 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. Structure, 31, 2023
|
|
8JOW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jow by Molmil](/molmil-images/mine/8jow) | |
8ECN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ecn by Molmil](/molmil-images/mine/8ecn) | Mycobacterium phage Ogopogo | Descriptor: | Major capsid protein | Authors: | Podgorski, J.M, White, S.J. | Deposit date: | 2022-09-02 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. Structure, 31, 2023
|
|
8EB4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8eb4 by Molmil](/molmil-images/mine/8eb4) | Gordonia phage Ziko | Descriptor: | Major capsid protein | Authors: | Podgorski, J.M, White, S.J. | Deposit date: | 2022-08-30 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. Structure, 31, 2023
|
|
8ECI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8eci by Molmil](/molmil-images/mine/8eci) | Arthrobacter phage Bridgette | Descriptor: | Decoration protein, Major capsid protein | Authors: | Podgorski, J.M, White, S.J. | Deposit date: | 2022-09-02 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. Structure, 31, 2023
|
|
8EC8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ec8 by Molmil](/molmil-images/mine/8ec8) | Mycobacterium phage Bobi | Descriptor: | Major capsid protein | Authors: | Podgorski, J.M, White, S.J. | Deposit date: | 2022-09-01 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. Structure, 31, 2023
|
|
8ECK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8eck by Molmil](/molmil-images/mine/8eck) | Gordonia phage Cozz | Descriptor: | Major capsid protein | Authors: | Podgorski, J.M, White, S.J. | Deposit date: | 2022-09-02 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. Structure, 31, 2023
|
|
8E16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e16 by Molmil](/molmil-images/mine/8e16) | Mycobacterium phage Che8 | Descriptor: | Major capsid protein, gp6 | Authors: | Podgorski, J.M, White, S.J. | Deposit date: | 2022-08-09 | Release date: | 2023-02-01 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. Structure, 31, 2023
|
|
1WO7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wo7 by Molmil](/molmil-images/mine/1wo7) | Solution structure of Designed Functional Finger 7 (DFF7): Designed mutant based on non-native CHANCE domain | Descriptor: | CREB Binding Protein, ZINC ION | Authors: | Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. | Deposit date: | 2004-08-12 | Release date: | 2005-03-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting Structure, 13, 2005
|
|
8E17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e17 by Molmil](/molmil-images/mine/8e17) | BRD4-D1 in complex with BET inhibitor | Descriptor: | (4P,6M)-6-[1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl]-4-[5-(methanesulfonyl)-2-methoxyphenyl]-2-methylisoquinolin-1(2H)-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | Authors: | Gorman, M.A, Fitzgerald, C.G.D, White, J.M, Parker, M.W. | Deposit date: | 2022-08-09 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography. Chem.Commun.(Camb.), 59, 2023
|
|
8E3W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e3w by Molmil](/molmil-images/mine/8e3w) | BRD4-D1 in complex with BET inhibitor | Descriptor: | (4P)-4-[2-(cyclopropylmethoxy)-5-(methanesulfonyl)phenyl]-2-methylisoquinolin-1(2H)-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | Authors: | Gorman, M.A, Fitzgerald, C.G.D, White, J.M, Parker, M.W. | Deposit date: | 2022-08-17 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography. Chem.Commun.(Camb.), 59, 2023
|
|
8DYR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dyr by Molmil](/molmil-images/mine/8dyr) | BRD4-D1 in complex with BET inhibitor | Descriptor: | (4P,6P)-4-[2-(cyclopropylmethoxy)-5-(methanesulfonyl)phenyl]-6-[1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl]-2-methylisoquinolin-1(2H)-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | Authors: | Gorman, M.A, Fitzgerald, C.G.D, White, J.M, Parker, M.W. | Deposit date: | 2022-08-04 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography. Chem.Commun.(Camb.), 59, 2023
|
|
1X5V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x5v by Molmil](/molmil-images/mine/1x5v) | NMR Structure of PcFK1 | Descriptor: | PcFK1 | Authors: | Pimentel, C, Choi, S.J, Chagot, B, Guette, C, Camadro, J.M, Darbon, H. | Deposit date: | 2005-05-17 | Release date: | 2006-04-04 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure of PcFK1, a spider peptide active against Plasmodium falciparum Protein Sci., 15, 2006
|
|
1WBQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wbq by Molmil](/molmil-images/mine/1wbq) | ZnMg substituted aminopeptidase P from E. coli | Descriptor: | CHLORIDE ION, MAGNESIUM ION, XAA-PRO AMINOPEPTIDASE, ... | Authors: | Graham, S.C, Bond, C.S, Freeman, H.C, Guss, J.M. | Deposit date: | 2004-11-05 | Release date: | 2005-09-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Functional Implications of Metal Ion Selection in Aminopeptidase P, a Metalloprotease with a Dinuclear Metal Center. Biochemistry, 44, 2005
|
|
1X8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x8b by Molmil](/molmil-images/mine/1x8b) | Structure of human Wee1A kinase: kinase domain complexed with inhibitor PD0407824 | Descriptor: | 9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE, MAGNESIUM ION, Wee1-like protein kinase | Authors: | Squire, C.J, Dickson, J.M, Ivanovic, I, Baker, E.N. | Deposit date: | 2004-08-17 | Release date: | 2005-06-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structure and inhibition of the human cell cycle checkpoint kinase, Wee1A kinase: an atypical tyrosine kinase with a key role in CDK1 regulation Structure, 13, 2005
|
|
1X9N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x9n by Molmil](/molmil-images/mine/1x9n) | Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA | Descriptor: | 5'-phosphorylated DNA, ADENOSINE MONOPHOSPHATE, DNA ligase I, ... | Authors: | Pascal, J.M, O'Brien, P.J, Tomkinson, A.E, Ellenberger, T. | Deposit date: | 2004-08-23 | Release date: | 2004-11-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Human DNA ligase I completely encircles and partially unwinds nicked DNA. Nature, 432, 2004
|
|
2XWE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xwe by Molmil](/molmil-images/mine/2xwe) | X-RAY STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH 5N,6S-(N'-(N-OCTYL)IMINO)-6-THIONOJIRIMYCIN IN THE ACTIVE SITE | Descriptor: | (3Z,5S,6R,7S,8R,8aS)-3-(octylimino)hexahydro[1,3]thiazolo[3,4-a]pyridine-5,6,7,8-tetrol, GLUCOSYLCERAMIDASE, PHOSPHATE ION, ... | Authors: | Brumshtein, B, Aguilar-Moncayo, M, Benito, J.M, Ortiz Mellet, C, Garcia Fernandez, J.M, Silman, I, Shaaltiel, Y, Sussman, J.L, Futerman, A.H. | Deposit date: | 2010-11-02 | Release date: | 2011-09-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Cyclodextrin-Mediated Crystallization of Acid Beta-Glucosidase in Complex with Amphiphilic Bicyclic Nojirimycin Analogues. Org.Biomol.Chem., 9, 2011
|
|
1XBA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xba by Molmil](/molmil-images/mine/1xba) | Crystal structure of apo syk tyrosine kinase domain | Descriptor: | Tyrosine-protein kinase SYK | Authors: | Atwell, S, Adams, J.M, Badger, J, Buchanan, M.D, Feil, I.K, Froning, K.J, Gao, X, Hendle, J, Keegan, K, Leon, B.C, Muller-Deickmann, H.J, Nienaber, V.L, Noland, B.W, Post, K, Rajashankar, K.R, Ramos, A, Russell, M, Burley, S.K, Buchanan, S.G. | Deposit date: | 2004-08-30 | Release date: | 2004-11-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase. J.Biol.Chem., 279, 2004
|
|
1XBO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xbo by Molmil](/molmil-images/mine/1xbo) | PTP1B complexed with Isoxazole Carboxylic Acid | Descriptor: | 5-(3-{3-[3-HYDROXY-2-(METHOXYCARBONYL)PHENOXY]PROPENYL}PHENYL)-4-(HYDROXYMETHYL)ISOXAZOLE-3-CARBOXYLIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | Authors: | Zhao, H, Liu, G, Xin, Z, Serby, M, Pei, Z, Szczepankiewicz, B.G, Hajduk, P.J, Abad-Zapatero, C, Hutchins, C.W, Lubben, T.H, Ballaron, S.J, Hassach, D.L, Kaszubska, W, Rondinone, C.M, Trevillyan, J.M, Jirousek, M.R. | Deposit date: | 2004-08-31 | Release date: | 2004-10-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors. Bioorg.Med.Chem.Lett., 14, 2004
|
|
8DZZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dzz by Molmil](/molmil-images/mine/8dzz) | Cryo-EM structure of chi dynein bound to Lis1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ... | Authors: | Reimer, J.M, Lahiri, I, Leschziner, A.E. | Deposit date: | 2022-08-08 | Release date: | 2023-08-30 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge. Nat.Struct.Mol.Biol., 30, 2023
|
|
8E06
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e06 by Molmil](/molmil-images/mine/8e06) | Symmetry expansion of dimeric LRRK1 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 1 | Authors: | Reimer, J.M, Lin, Y.X, Leschziner, A.E. | Deposit date: | 2022-08-08 | Release date: | 2023-08-30 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure of LRRK1 and mechanisms of autoinhibition and activation. Nat.Struct.Mol.Biol., 30, 2023
|
|