8DBI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dbi by Molmil](/molmil-images/mine/8dbi) | Human PRPS1 with Phosphate, ATP, and R5P; Hexamer | 分子名称: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Hvorecny, K.L, Kollman, J.M. | 登録日 | 2022-06-14 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | Human PRPS1 filaments stabilize allosteric sites to regulate activity. Nat.Struct.Mol.Biol., 30, 2023
|
|
8DBH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dbh by Molmil](/molmil-images/mine/8dbh) | |
1XMI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xmi by Molmil](/molmil-images/mine/1xmi) | Crystal structure of human F508A NBD1 domain with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | 著者 | Lewis, H.A, Zhao, X, Wang, C, Sauder, J.M, Rooney, I, Noland, B.W, Lorimer, D, Kearins, M.C, Conners, K, Condon, B, Maloney, P.C, Guggino, W.B, Hunt, J.F, Emtage, S, Structural GenomiX | 登録日 | 2004-10-02 | 公開日 | 2004-11-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure J.Biol.Chem., 280, 2005
|
|
2XWD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xwd by Molmil](/molmil-images/mine/2xwd) | X-RAY STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH 5N,6O-(N'-(N-OCTYL)IMINO)NOJIRIMYCIN IN THE ACTIVE SITE | 分子名称: | (3Z,5S,6R,7S,8R,8aR)-3-(octylimino)hexahydro[1,3]oxazolo[3,4-a]pyridine-5,6,7,8-tetrol, GLUCOSYLCERAMIDASE, SULFATE ION, ... | 著者 | Brumshtein, B, Aguilar-Moncayo, M, Benito, J.M, Ortiz Mellet, C, Garcia Fernandez, J.M, Silman, I, Shaaltiel, Y, Sussman, J.L, Futerman, A.H. | 登録日 | 2010-11-01 | 公開日 | 2011-09-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Cyclodextrin-Mediated Crystallization of Acid Beta-Glucosidase in Complex with Amphiphilic Bicyclic Nojirimycin Analogues. Org.Biomol.Chem., 9, 2011
|
|
1X8E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x8e by Molmil](/molmil-images/mine/1x8e) | Crystal structure of Pyrococcus furiosus phosphoglucose isomerase free enzyme | 分子名称: | Glucose-6-phosphate isomerase | 著者 | Berrisford, J.M, Akerboom, J, Brouns, S, Sedelnikova, S.E, Turnbull, A.P, van der Oost, J, Salmon, L, Hardre, R, Murray, I.A, Blackburn, G.M, Rice, D.W, Baker, P.J. | 登録日 | 2004-08-18 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis. J.Mol.Biol., 343, 2004
|
|
1XOD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xod by Molmil](/molmil-images/mine/1xod) | Crystal structure of X. tropicalis Spred1 EVH-1 domain | 分子名称: | GLYCEROL, Spred1 | 著者 | Harmer, N.J, Sivak, J.M, Amaya, E, Blundell, T.L. | 登録日 | 2004-10-06 | 公開日 | 2005-01-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | 1.15A Crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family Febs Lett., 579, 2005
|
|
1XOK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xok by Molmil](/molmil-images/mine/1xok) | crystal structure of alfalfa mosaic virus RNA 3'UTR in complex with coat protein N terminal peptide | 分子名称: | BROMIDE ION, Coat protein, alfalfa mosaic virus RNA 3' UTR | 著者 | Guogas, L.M, Filman, D.J, Hogle, J.M, Gehrke, L. | 登録日 | 2004-10-06 | 公開日 | 2005-01-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Cofolding organizes alfalfa mosaic virus RNA and coat protein for replication. Science, 306, 2004
|
|
1XGD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xgd by Molmil](/molmil-images/mine/1xgd) | Apo R268A human aldose reductase | 分子名称: | Aldose reductase | 著者 | Brownlee, J.M, Bohren, K.M, Milne, A.C, Gabbay, K.H, Harrison, D.H.T. | 登録日 | 2004-09-16 | 公開日 | 2005-03-29 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The structure of Apo R268A human aldose reductase: Hinges and latches that control the kinetic mechanism Biochim.Biophys.Acta, 1748, 2005
|
|
8CTQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ctq by Molmil](/molmil-images/mine/8ctq) | Crystal structure of engineered phospholipase D mutant superPLD 2-48 | 分子名称: | PHOSPHATE ION, Phospholipase D | 著者 | Tei, R, Bagde, S.R, Fromme, J.C, Baskin, J.M. | 登録日 | 2022-05-16 | 公開日 | 2023-04-26 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Activity-based directed evolution of a membrane editor in mammalian cells. Nat.Chem., 15, 2023
|
|
1XPR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xpr by Molmil](/molmil-images/mine/1xpr) | Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic 5a-formylbicyclomycin (FB) | 分子名称: | 5'-R(*CP*UP*CP*UP*CP*UP*CP*U)-3', 5A-FORMYLBICYCLOMYCIN, MAGNESIUM ION, ... | 著者 | Skordalakes, E, Brogan, A.P, Park, B.S, Kohn, H, Berger, J.M. | 登録日 | 2004-10-09 | 公開日 | 2004-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural mechanism of inhibition of the rho transcription termination factor by the antibiotic bicyclomycin Structure, 13, 2005
|
|
1XQ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xq9 by Molmil](/molmil-images/mine/1xq9) | |
5OTG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5otg by Molmil](/molmil-images/mine/5otg) | |
8ERN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ern by Molmil](/molmil-images/mine/8ern) | Cyclin-free CDK2 in complex with Cpd21 | 分子名称: | Cyclin-dependent kinase 2, GLYCEROL, N,3-dimethyl-4-({7-[(2S)-2-methylpyrrolidine-1-carbonyl]quinazolin-2-yl}amino)benzene-1-sulfonamide | 著者 | Murray, J.M, Oh, A. | 登録日 | 2022-10-12 | 公開日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Cyclin-free CDK2 in complex with Cpd21 To Be Published
|
|
1UVI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uvi by Molmil](/molmil-images/mine/1uvi) | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 6nt RNA | 分子名称: | 5'-R(*UP*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | 登録日 | 2004-01-21 | 公開日 | 2004-02-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
|
|
8ERD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8erd by Molmil](/molmil-images/mine/8erd) | Cyclin-free CDK2 in complex with Cpd17 | 分子名称: | (2-{[1-(methanesulfonyl)piperidin-4-yl]amino}quinazolin-7-yl)[(2S)-2-methylpyrrolidin-1-yl]methanone, Cyclin-dependent kinase 2 | 著者 | Murray, J.M, Oh, A. | 登録日 | 2022-10-11 | 公開日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Cyclin-free CDK2 in complex with Cpd17 To Be Published
|
|
1UUZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uuz by Molmil](/molmil-images/mine/1uuz) | IVY:A NEW FAMILY OF PROTEIN | 分子名称: | INHIBITOR OF VERTEBRATE LYSOZYME, LYSOZYME C | 著者 | Abergel, C, Lembo, F, Byrne, D, Maza, C, Claverie, J.M. | 登録日 | 2004-01-12 | 公開日 | 2004-01-14 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and Evolution of the Ivy Protein Family, Unexpected Lysozyme Inhibitors in Gram-Negative Bacteria. Proc.Natl.Acad.Sci.USA, 104, 2007
|
|
2PLV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2plv by Molmil](/molmil-images/mine/2plv) | |
1XQ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xq7 by Molmil](/molmil-images/mine/1xq7) | |
1XUJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xuj by Molmil](/molmil-images/mine/1xuj) | TRYPSIN-KETO-BABIM-ZN+2, PH 8.2 | 分子名称: | BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANONE ZINC, CALCIUM ION, SULFATE ION, ... | 著者 | Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M. | 登録日 | 1997-10-10 | 公開日 | 1998-11-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Design of potent selective zinc-mediated serine protease inhibitors. Nature, 391, 1998
|
|
1XIP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xip by Molmil](/molmil-images/mine/1xip) | |
1XUH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xuh by Molmil](/molmil-images/mine/1xuh) | TRYPSIN-KETO-BABIM-CO+2, PH 8.2 | 分子名称: | BIS(5-AMIDINO-2-BENZIMIDAZOLYL)METHANONE, CALCIUM ION, COBALT (II) ION, ... | 著者 | Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M. | 登録日 | 1997-10-10 | 公開日 | 1998-11-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Design of potent selective zinc-mediated serine protease inhibitors. Nature, 391, 1998
|
|
1YH5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yh5 by Molmil](/molmil-images/mine/1yh5) | Solution NMR Structure of Protein yggU from Escherichia coli. Northeast Structural Genomics Consortium Target ER14. | 分子名称: | ORF, HYPOTHETICAL PROTEIN | 著者 | Aramini, J.M, Xiao, R, Huang, Y.J, Acton, T.B, Wu, M.J, Mills, J.L, Tejero, R.T, Szyperski, T, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2005-01-06 | 公開日 | 2005-02-01 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Hypothetical Protein Yggu from E. Coli. Northeast Structural Genomics Consortium Target Er14. To be Published
|
|
1Y50
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y50 by Molmil](/molmil-images/mine/1y50) | X-ray crystal structure of Bacillus stearothermophilus Histidine phosphocarrier protein (Hpr) F29W mutant domain_swapped dimer | 分子名称: | Phosphocarrier protein HPr, SULFATE ION | 著者 | Sridharan, S, Razvi, A, Scholtz, J.M, Sacchettini, J.C. | 登録日 | 2004-12-01 | 公開日 | 2005-02-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers. J.Mol.Biol., 346, 2005
|
|
1Y5R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y5r by Molmil](/molmil-images/mine/1y5r) | The crystal structure of murine 11b-hydroxysteroid dehydrogenase complexed with corticosterone | 分子名称: | CORTICOSTERONE, Corticosteroid 11-beta-dehydrogenase, isozyme 1, ... | 著者 | Zhang, J, Osslund, T.D, Plant, M.H, Clogston, C.L, Nybo, R.E, Xiong, F, Delaney, J.M, Jordan, S. | 登録日 | 2004-12-02 | 公開日 | 2005-05-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of Murine 11-Hydroxysteroid Dehydrogenase 1: An Important Therapeutic Target for Diabetes Biochemistry, 44, 2005
|
|
8P9T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p9t by Molmil](/molmil-images/mine/8p9t) | Crystal structure of the metallo-beta-lactamase VIM1 with 2483 | 分子名称: | 7-[(1~{S})-1-(4-azanylbutanoyloxy)ethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION | 著者 | Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J. | 登録日 | 2023-06-06 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Crystal structure of the metallo-beta-lactamase VIM1 with 2483 To Be Published
|
|