4F0R
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![BU of 4f0r by Molmil](/molmil-images/mine/4f0r) | Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) bound Zn and 5'-Methylthioadenosine (unproductive complex) | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, 5-methylthioadenosine/S-adenosylhomocysteine deaminase, GLYCEROL, ... | 著者 | Kim, J, Vetting, M.W, Sauder, J.M, Burley, S.K, Raushel, F.M, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2012-05-04 | 公開日 | 2012-06-06 | 最終更新日 | 2021-02-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) bound Zn and 5'-Methylthioadenosine (unproductive complex) To be Published
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2YMD
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![BU of 2ymd by Molmil](/molmil-images/mine/2ymd) | Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with serotonin (5-hydroxytryptamine) | 分子名称: | GLYCEROL, PHOSPHATE ION, SEROTONIN, ... | 著者 | Kesters, D, Thompson, A.J, Brams, M, Elk, R.v, Spurny, R, Geitmann, M, Villalgordo, J.M, Guskov, A, Danielson, U.H, Lummis, S.C.R, Smit, A.B, Ulens, C. | 登録日 | 2012-10-09 | 公開日 | 2012-12-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural Basis of Ligand Recognition in 5-Ht(3) Receptors. Embo Rep., 14, 2013
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1G6Q
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![BU of 1g6q by Molmil](/molmil-images/mine/1g6q) | CRYSTAL STRUCTURE OF YEAST ARGININE METHYLTRANSFERASE, HMT1 | 分子名称: | HNRNP ARGININE N-METHYLTRANSFERASE | 著者 | Weiss, V.H, McBride, A.E, Soriano, M.A, Filman, D.J, Silver, P.A, Hogle, J.M. | 登録日 | 2000-11-07 | 公開日 | 2000-12-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The structure and oligomerization of the yeast arginine methyltransferase, Hmt1. Nat.Struct.Biol., 7, 2000
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2Y9F
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![BU of 2y9f by Molmil](/molmil-images/mine/2y9f) | High-resolution Structural Insights on the Sugar-recognition and Fusion Tag Properties of a Versatile b-Trefoil Lectin Domain | 分子名称: | HEMOLYTIC LECTIN LSLA | 著者 | Angulo, I, Acebron, I, de las Rivas, B, Munoz, R, Rodriguez, J.I, Menendez, M, Garcia, P, Tateno, H, Goldstein, I.J, Perez-Agote, B, Mancheno, J.M. | 登録日 | 2011-02-14 | 公開日 | 2011-10-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | High-Resolution Structural Insights on the Sugar-Recognition and Fusion Tag Properties of a Versatile Beta-Trefoil Lectin Domain from the Mushroom Laetiporus Sulphureus. Glycobiology, 21, 2011
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4EZ1
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![BU of 4ez1 by Molmil](/molmil-images/mine/4ez1) | Crystal structure of acetylcholine binding protein (AChBP) from Aplysia Californica in complex with alpha-conotoxin BuIA | 分子名称: | Alpha-conotoxin BuIA, MANGANESE (II) ION, Soluble acetylcholine receptor | 著者 | Talley, T.T, Reger, A.S, Kim, C, Sankaran, B, Ho, K, Taylor, P, McIntosh, J.M. | 登録日 | 2012-05-02 | 公開日 | 2013-05-08 | 最終更新日 | 2013-06-19 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Pairwise interaction of alpha-conotoxin BuIA Pro6 with the beta subunit of nicotinic acetylcholine receptor To be Published
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1JR5
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![BU of 1jr5 by Molmil](/molmil-images/mine/1jr5) | Solution Structure of the Anti-Sigma Factor AsiA Homodimer | 分子名称: | 10 KDA Anti-Sigma Factor | 著者 | Urbauer, J.L, Simeonov, M.F, Bieber Urbauer, R.J, Adelman, K, Gilmore, J.M, Brody, E.N. | 登録日 | 2001-08-10 | 公開日 | 2002-02-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and stability of the anti-sigma factor AsiA: implications for novel functions. Proc.Natl.Acad.Sci.USA, 99, 2002
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4F09
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![BU of 4f09 by Molmil](/molmil-images/mine/4f09) | |
4HPT
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![BU of 4hpt by Molmil](/molmil-images/mine/4hpt) | Crystal structure of the catalytic subunit of cAMP-dependent protein kinase displaying complete phosphoryl transfer of AMP-PNP onto a substrate peptide | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... | 著者 | Bastidas, A.C, Steichen, J.M, Wu, J, Taylor, S.S. | 登録日 | 2012-10-24 | 公開日 | 2013-03-20 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Phosphoryl transfer by protein kinase a is captured in a crystal lattice. J.Am.Chem.Soc., 135, 2013
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5I7X
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![BU of 5i7x by Molmil](/molmil-images/mine/5i7x) | BRD9 in complex with Cpd2 (N,N-dimethyl-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamide) | 分子名称: | Bromodomain-containing protein 9, N,N-dimethyl-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamide | 著者 | Murray, J.M. | 登録日 | 2016-02-18 | 公開日 | 2016-10-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.1752 Å) | 主引用文献 | Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains. J.Med.Chem., 59, 2016
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5I8G
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![BU of 5i8g by Molmil](/molmil-images/mine/5i8g) | CBP in complex with Cpd637 ((R)-4-methyl-6-(1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl)-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one) | 分子名称: | (4R)-4-methyl-6-[1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl]-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one, 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Murray, J.M. | 登録日 | 2016-02-18 | 公開日 | 2016-04-20 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637). Acs Med.Chem.Lett., 7, 2016
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4HPU
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![BU of 4hpu by Molmil](/molmil-images/mine/4hpu) | Crystal structure of the catalytic subunit of cAMP-dependent protein kinase displaying partial phosphoryl transfer of AMP-PNP onto a substrate peptide | 分子名称: | MAGNESIUM ION, MYRISTIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Bastidas, A.C, Steichen, J.M, Wu, J, Taylor, S.S. | 登録日 | 2012-10-24 | 公開日 | 2013-03-20 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Phosphoryl transfer by protein kinase a is captured in a crystal lattice. J.Am.Chem.Soc., 135, 2013
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4HKQ
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![BU of 4hkq by Molmil](/molmil-images/mine/4hkq) | XMRV reverse transcriptase in complex with RNA/DNA hybrid | 分子名称: | DNA (5'-D(*TP*GP*GP*AP*AP*TP*CP*A*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), RNA (5'-R(*AP*AP*CP*AP*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*CP*AP*U)-3'), Reverse transcriptase/ribonuclease H p80 | 著者 | Nowak, E, Potrzebowski, W, Konarev, P.V, Rausch, J.W, Bona, M.K, Svergun, D.I, Bujnicki, J.M, Le Grice, S.F.J, Nowotny, M. | 登録日 | 2012-10-15 | 公開日 | 2013-02-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | 主引用文献 | Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid Nucleic Acids Res., 41, 2013
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2ZCG
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![BU of 2zcg by Molmil](/molmil-images/mine/2zcg) | |
2ZIW
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![BU of 2ziw by Molmil](/molmil-images/mine/2ziw) | Crystal structure of the Mus81-Eme1 complex | 分子名称: | Crossover junction endonuclease EME1, Mus81 protein | 著者 | Chang, J.H, Kim, J.J, Choi, J.M, Lee, J.H, Cho, Y. | 登録日 | 2008-02-25 | 公開日 | 2008-04-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the Mus81-Eme1 complex Genes Dev., 22, 2008
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2ZL6
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![BU of 2zl6 by Molmil](/molmil-images/mine/2zl6) | Atomic resolution structural characterization of recognition of histo-blood group antigens by Norwalk virus | 分子名称: | 58 kd capsid protein, ACETATE ION, MAGNESIUM ION, ... | 著者 | Choi, J.M, Huston, A.M, Estes, M.K, Prasad, B.V.V. | 登録日 | 2008-04-02 | 公開日 | 2008-07-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Atomic resolution structural characterization of recognition of histo-blood group antigens by Norwalk virus Proc.Natl.Acad.Sci.Usa, 105, 2008
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2ZJP
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![BU of 2zjp by Molmil](/molmil-images/mine/2zjp) | Thiopeptide antibiotic Nosiheptide bound to the large ribosomal subunit of Deinococcus radiodurans | 分子名称: | 4-(hydroxymethyl)-3-methyl-1H-indole-2-carboxylic acid, 50S RIBOSOMAL PROTEIN L11, 50S RIBOSOMAL PROTEIN L13, ... | 著者 | Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. | 登録日 | 2008-03-07 | 公開日 | 2008-06-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin. Mol.Cell, 30, 2008
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1ONZ
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![BU of 1onz by Molmil](/molmil-images/mine/1onz) | Oxalyl-aryl-Amino Benzoic acid Inhibitors of PTP1B, compound 8b | 分子名称: | 2-[(7-HYDROXY-NAPHTHALEN-1-YL)-OXALYL-AMINO]-BENZOIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | 著者 | Liu, G, Szczepankiewicz, B.G, Pei, Z, Janowich, D.A, Xin, Z, Hadjuk, P.J, Abad-Zapatero, C, Liang, H, Hutchins, C.W, Fesik, S.W, Ballaron, S.J, Stashko, M.A, Lubben, T, Mika, A.K, Zinker, B.A, Trevillyan, J.M, Jirousek, M.R. | 登録日 | 2003-03-02 | 公開日 | 2003-05-20 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery and Structure-Activity Relationship of Oxalylarylaminobenzoic
Acids as Inhibitors of Protein Tyrosine Phosphatase 1B J.Med.Chem., 46, 2003
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5I88
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![BU of 5i88 by Molmil](/molmil-images/mine/5i88) | BRD4 in complex with Cpd4 ((E)-3-(6-(but-2-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,N-dimethylbenzamide) | 分子名称: | 1,2-ETHANEDIOL, 3-{6-[(2E)-but-2-en-1-yl]-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl}-N,N-dimethylbenzamide, Bromodomain-containing protein 4, ... | 著者 | Murray, J.M. | 登録日 | 2016-02-18 | 公開日 | 2016-10-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains. J.Med.Chem., 59, 2016
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2IO6
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![BU of 2io6 by Molmil](/molmil-images/mine/2io6) | Wee1 kinase complexed with inhibitor PD330961 | 分子名称: | 9-HYDROXY-6-(3-HYDROXYPROPYL)-4-(2-METHOXYPHENYL)PYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE, Wee1-like protein kinase | 著者 | Squire, C.J, Dickson, J.M, Ivanovic, I, Baker, E.N. | 登録日 | 2006-10-10 | 公開日 | 2007-09-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases. Eur.J.Med.Chem., 43, 2008
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1N32
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![BU of 1n32 by Molmil](/molmil-images/mine/1n32) | Structure of the Thermus thermophilus 30S ribosomal subunit bound to codon and near-cognate transfer RNA anticodon stem-loop mismatched at the first codon position at the a site with paromomycin | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Ogle, J.M, Murphy IV, F.V, Tarry, M.J, Ramakrishnan, V. | 登録日 | 2002-10-25 | 公開日 | 2002-11-29 | 最終更新日 | 2019-11-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form Cell(Cambridge,Mass.), 111, 2002
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1P69
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![BU of 1p69 by Molmil](/molmil-images/mine/1p69) | STRUCTURAL BASIS FOR VARIATION IN ADENOVIRUS AFFINITY FOR THE CELLULAR RECEPTOR CAR (P417S MUTANT) | 分子名称: | Coxsackievirus and adenovirus receptor, Fiber protein | 著者 | Howitt, J, Bewley, M.C, Graziano, V, Flanagan, J.M, Freimuth, P. | 登録日 | 2003-04-29 | 公開日 | 2004-05-11 | 最終更新日 | 2018-08-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for variation in adenovirus affinity for the cellular coxsackievirus and adenovirus receptor. J.Biol.Chem., 278, 2003
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2IN6
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![BU of 2in6 by Molmil](/molmil-images/mine/2in6) | Wee1 kinase complex with inhibitor PD311839 | 分子名称: | 3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID, Wee1-like protein kinase | 著者 | Squire, C.J, Dickson, J.M, Ivanovic, I, Baker, E.N. | 登録日 | 2006-10-05 | 公開日 | 2007-09-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases. Eur.J.Med.Chem., 43, 2008
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2Z2A
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![BU of 2z2a by Molmil](/molmil-images/mine/2z2a) | Thr109Gly dihydroorotase from E. coli | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | 著者 | Lee, M, Maher, M.J, Guss, J.M. | 登録日 | 2007-05-17 | 公開日 | 2007-10-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
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4G28
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![BU of 4g28 by Molmil](/molmil-images/mine/4g28) | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and EBIO-1 | 分子名称: | 1-ethyl-1,3-dihydro-2H-benzimidazol-2-one, CALCIUM ION, Calmodulin, ... | 著者 | Zhang, M, Pascal, J.M, Zhang, J.-F. | 登録日 | 2012-07-11 | 公開日 | 2012-09-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Identification of the functional binding pocket for compounds targeting small-conductance Ca(2+)-activated potassium channels. Nat Commun, 3, 2012
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4GDM
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![BU of 4gdm by Molmil](/molmil-images/mine/4gdm) | Crystal Structure of E.coli MenH | 分子名称: | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, CHLORIDE ION, GLYCEROL, ... | 著者 | Johnston, J.M, Baker, E.N, Guo, Z, Jiang, M. | 登録日 | 2012-07-31 | 公開日 | 2013-05-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal Structures of E. coli Native MenH and Two Active Site Mutants. Plos One, 8, 2013
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