8I9R
| Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State 5S RNP | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, 60S ribosomal protein L16-like protein, ... | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | Deposit date: | 2023-02-07 | Release date: | 2023-05-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Embo Rep., 24, 2023
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1I0V
| Ribonuclease T1 in complex with 2'GMP (form I crystal) | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1 | Authors: | De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R. | Deposit date: | 2001-01-30 | Release date: | 2001-02-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.234 Å) | Cite: | The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution. Eur.J.Biochem., 268, 2001
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7EF0
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7XO2
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7AJU
| Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2020-09-29 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome. Mol.Cell, 81, 2021
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1I0X
| RIBONUCLEASE T1 IN COMPLEX WITH 2'GMP (FORM II CRYSTAL) | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1 | Authors: | De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R. | Deposit date: | 2001-01-30 | Release date: | 2001-02-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution. Eur.J.Biochem., 268, 2001
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7XO1
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8I9V
| Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-2 | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | Deposit date: | 2023-02-07 | Release date: | 2023-05-17 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Embo Rep., 24, 2023
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7XO0
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7B08
| TgoT apo | Descriptor: | DNA polymerase, THYMIDINE-5'-TRIPHOSPHATE, TRIETHYLENE GLYCOL | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-18 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.394 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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7XO3
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2Q5L
| X-ray structure of phenylpyruvate decarboxylase in complex with 2-(1-hydroxyethyl)-3-deaza-ThDP | Descriptor: | 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-[(1R)-1-HYDROXYETHYL]-3-METHYL-2-THIENYL}ETHYL TRIHYDROGEN DIPHOSPHATE, 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-[(1S)-1-HYDROXYETHYL]-3-METHYL-2-THIENYL}ETHYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Versees, W, Spaepen, S, Wood, M.D, Leeper, F.J, Vanderleyden, J, Steyaert, J. | Deposit date: | 2007-06-01 | Release date: | 2007-10-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase. J.Biol.Chem., 282, 2007
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7XN4
| Cryo-EM structure of CopC-CaM-caspase-3 with NAD+ | Descriptor: | Arginine ADP-riboxanase CopC, Calmodulin-1, Caspase-3, ... | Authors: | Zhang, K, Peng, T, Tao, X.Y, Tian, M, Li, Y.X, Wang, Z, Ma, S.F, Hu, S.F, Pan, X, Xue, J, Luo, J.W, Wu, Q.L, Fu, Y, Li, S. | Deposit date: | 2022-04-28 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin. Mol.Cell, 82, 2022
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7AHC
| OpuA apo inward-facing | Descriptor: | ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component | Authors: | Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B. | Deposit date: | 2020-09-24 | Release date: | 2020-11-25 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA. Sci Adv, 6, 2020
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8I9W
| Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Dbp10-3 | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | Deposit date: | 2023-02-07 | Release date: | 2023-05-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Embo Rep., 24, 2023
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3KNG
| Crystal structure of SnoaB, a cofactor-independent oxygenase from Streptomyces nogalater, determined to 1.9 resolution | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... | Authors: | Koskiniemi, H, Grocholski, T, Lindqvist, Y, Mantsala, P, Niemi, J, Schneider, G. | Deposit date: | 2009-11-12 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the cofactor-independent monooxygenase SnoaB from Streptomyces nogalater: implications for the reaction mechanism Biochemistry, 49, 2010
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2IAS
| Crystal structure of squid ganglion DFPase W244F mutant | Descriptor: | CALCIUM ION, Diisopropylfluorophosphatase | Authors: | Scharff, E.I, Koepke, J, Fritzsch, G, Luecke, C, Rueterjans, H. | Deposit date: | 2006-09-08 | Release date: | 2006-09-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris Structure, 9, 2001
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8I9Y
| Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-2 | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | Deposit date: | 2023-02-07 | Release date: | 2023-05-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Embo Rep., 24, 2023
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7XNK
| human KCNQ1-CaM in complex with ML277 | Descriptor: | (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide, Calmodulin-3, POTASSIUM ION, ... | Authors: | Ma, D, Guo, J. | Deposit date: | 2022-04-29 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers. Proc.Natl.Acad.Sci.USA, 119, 2022
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2Q82
| Crystal structure of core protein P7 from Pseudomonas phage phi12. Northeast Structural Genomics Target OC1 | Descriptor: | Core protein P7 | Authors: | Benach, J, Eryilmaz, E, Su, M, Seetharaman, J, Wei, H, Gottlieb, P, Hunt, J.F, Ghose, R, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-06-08 | Release date: | 2007-08-07 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structure and dynamics of the P7 protein from the bacteriophage phi 12. J.Mol.Biol., 382, 2008
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7AJT
| Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2020-09-29 | Release date: | 2020-12-30 | Last modified: | 2021-02-03 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome. Mol.Cell, 81, 2021
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7XNI
| human KCNQ1-CaM in apo state | Descriptor: | Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 1 | Authors: | Ma, D, Guo, J. | Deposit date: | 2022-04-28 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers. Proc.Natl.Acad.Sci.USA, 119, 2022
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8HZW
| The NMR structure of noursinH11W peptide | Descriptor: | noursinH11W | Authors: | Yao, H, Li, Y, Zhang, T, Gao, J, Wang, H. | Deposit date: | 2023-01-09 | Release date: | 2023-05-31 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks. Nat Commun, 14, 2023
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7B3B
| Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with Remdesivir at position -3 (structure 1) | Descriptor: | DNA/RNA (5'-R(P*CP*UP*AP*CP*GP*CP*G)-D(P*(RMP))-R(P*UP*G)-3'), Non-structural protein 7, Non-structural protein 8, ... | Authors: | Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. | Deposit date: | 2020-11-30 | Release date: | 2020-12-23 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nat Commun, 12, 2021
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7XNL
| human KCNQ1-CaM-ML277-PIP2 complex in state A | Descriptor: | (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide, Calmodulin-3, POTASSIUM ION, ... | Authors: | Ma, D, Guo, J. | Deposit date: | 2022-04-29 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers. Proc.Natl.Acad.Sci.USA, 119, 2022
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